Rosalind Marie Curie Franklin · Marie Curie Rosalind Franklin Lise Meitner Ada Lovelace
Introducing ROSALIND
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Transcript of Introducing ROSALIND
When it comes to
cancer chemotherapy,
“one size does not fit all.”
Ideally, an individual’s
chemotherapy should be
tailored to the gene mutation
of the tumor in question
There are hundreds of cancer drugs
and hundreds of thousands of drug
combinations
Too much for any doctor, or
team of doctors, to consider
Developed to determine better
personalized treatment options
based on a patient’s genetic profile
ROSALINDTM
a smart
data
platform
ROSALIND’s scientific premise
Gene mutations found in a tumor
lead to mutations in proteins
Mutated proteins result in abnormal
cell signaling and can lead to cancer
To be effective cancer therapy must
aim to restore normal cell signaling
ROSALIND evaluates data
from a tumor’s gene
mutation profile and
recommends treatments
most likely to restore
normal cell signaling
1
2
3
An input vector composed of the genetic
profile of the tumor to be simulated
A dynamic representation of positive &
negative interactions between cell
signaling proteins
An output vector identifying potential
remission inducing drug combinations
3 basic components to ROSALIND
Step 1: Obtain a gene mutation
profile from a biopsy of the patient’s
tumor
Step 2: A physician must send a
confidential copy of the gene
mutation profile to COTI*
Our 5 step process
* Critical Outcome Technologies Inc.
Step 4: COTI reviews and interprets
the simulation output
Step 5: COTI sends the simulation
output to the ordering physician for
treatment consideration
NOTE: The simulation output drug combinations only include drugs currently approved or in clinical trials
If you have cancer, you want the best
treatment for your specific tumor.
Ask your doctor about
ROSALIND today
Visit our website
www.ROSALINDonline.com
Share our story online:
Follow ROSALINDonline
on Facebook and
#ROSALIND
#Personalized
CancerCare
Disclaimer:
ROSALIND is a patent pending computational research and personalized cancer caretool that continues to undergo development and real world validation.
ROSALIND is not intended to replace or supersede the assessments or decisions ofany experienced physician or group of physicians.
The ROSALIND information is NOT a prescription for any treatment(s) and in no wayobligates any physician or group of physicians to use any part of the informationprovided in any way.
The sole purpose of ROSALIND is to provide information only regarding treatmentoptions that might otherwise not have been considered.
ROSALIND only considers drugs that have been approved for the treatment of cancer.
ROSALIND should not be used without the express and informed consent of thepatient. By using ROSALIND, the physician acknowledges that he or she has obtainedthis consent.
ROSALIND does not warrant or guarantee the effectiveness of its informational outputto the physician.