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![Page 1: Interventional MRI Magnetoencephalography Verification of Functional Imaging with Interventional MRI: Mapping of Epilepsy and Eloquent Cortex.](https://reader035.fdocuments.us/reader035/viewer/2022062322/56649e4f5503460f94b4661d/html5/thumbnails/1.jpg)
Interventional MRIMagnetoencephalography
Verification of Functional Imaging with Interventional MRI: Mapping of Epilepsy and Eloquent Cortex
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Steven Stufflebeam, M.D. (MGH)Ronald Kikinis, M.D. (BWH)
Partners Radiology Research Award
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Interictal Spike Localization
MEG
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Greg Sorensen
Structural Connectivity: DTI Tractography
Functional Connectivity:BOLD fMRI
Vincent & Buckner, 2006
Effective Connectivity:MEG dynamic SEM
Fa-Hsuan Lin
Brain Connectivity
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Combining Advanced Imaging Technologies: Sum is greater than the Parts
Tumor, MEG, MRAngo, DTI fMRI
Stephen Piper, Ph.D.
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DTI
T2 MRI Tumor
Isopoential Field Maps (MEG)
MEG Dipole For Language Stimuli
Language Mapping in Temporal Lobe Tumor
CDr. Alexandra Golby Dr. Ralph SuarezDr. Ronald Kikinis.Dr. Stufflebeam
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Dr. Alex Golby Dr. Ralph Suarez.Dr. Stufflebeam
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Why is this research important?
• Translational research: bench to bedside.• Multidisciplinary and cross-institutional: Physics, software
engineering, mathematics, neurosurgery, neurology.• Leverages the resources of the BWH & MGH to advance
researchdirectly to patients/physicians.– 250 epilepsy & brain tumor patients from MGH/BWH
– Awards at ISCAMEG, HBM, ISB
– HST.583 Imaging Biophysics & Clin Apps
– Grants R01, P41, K08, K25, CIMIT
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Thanks
BWH
• Ron Kikikis
• Stephen Piper
• Ferenc Jolesz
• Ralph Suarez
• Alexandra Golby
• Joseph Madsen
• Ed Bromfield
• Barabara Dworetzky
• Jong Lee
MGH/Martinos Center• Emad Eskandar• Reese Cosgrove• Andy Cole• Ronan Kilbride• Matti Hamalainen• Fa-Hsuan Lin• Greg Sorensen• Randy Buckner• Gordon Harris• Giorgio Bonmassar