Internet-based surveillance of illness: the FluSurvey platform
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Internet-based surveillance of illness: the FluSurvey platform Sebastian Funk Centre for the Mathematical Modelling of Infectious Diseases London School of Hygiene & Tropical Medicine v (} Z uZuo u}oo]vP of ]v(} ]
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Transcript of Internet-based surveillance of illness: the FluSurvey platform
Internet-based surveillance of illness: theFluSurvey platform
Sebastian Funk
Centre for the Mathematical Modelling of Infectious DiseasesLondon School of Hygiene & Tropical Medicine
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The flu pyramid
Infections
Cases
GP
The flu pyramid
≈70%
Infections
Cases
GP
The flu pyramid
?
≈70%
Infections
Cases
GP
Web-based community surveillance
FluSurvey
Beginning of the flu season
Weekly symptom survey
Other surveys
Results page
FluSurvey participants
0
2000
4000
6000
2010 2011 2012 2013 2014 2015
Num
ber
of p
artic
ipan
ts
Science: school holidays and the H1N1 pandemic
Term time School holidays
Par
ticip
ant a
ge
Contact age Contact age
Science: school holidays and the H1N1 pandemic
Case estimates Model fit
Science: risk factors
Variable OR PFemale 1.52 0.03Unvaccinated 1.94 <0.00118-24 0.95 0.8025-34 1.12 0.5035-44 1.42 0.0345-64 1.51 0.00765+ 0.95 0.79Contact with children 1.47 <0.001Live with children 1.10 0.305Smoker 1.32 0.01Take public transport 0.91 0.183Underlying health condition 1.53 <0.001Employment status 0.92 0.066
Science: QALY loss
0-17 18-44 45-64 65+
n = 106
n = 69
n = 64
n = 651
n = 525
n = 437
n = 411
n = 319
n = 311
n = 152
n = 88
n = 52
75
50
25
0
75
50
25
0
100
75
50
25
0
AR
IIL
I no
feve
rIL
I feve
r
0 5 10 15 0 5 10 15 0 5 10 15 0 5 10 15
days since symptom onset
dro
p in
he
alth
sco
re
data confidence IQR 95%
Science: QALY loss
0.0
0.5
1.0
1.5
2.0
ARI ILIno fever ILIfever
symptom severity
me
dia
n Q
AL
D lo
ss
Science: vaccine efficacy
0.2
.4.6
2011-12 2012-13 2013-14 2014-15Season
Visit total Time in study
Time until March end
With 95% confidence interval
Science: severity
ARI ILI no fever ILI fever
n = 196 n = 1169 n = 730 n = 280 n = 112 n = 809 n = 473 n = 125 n = 85 n = 610 n = 391 n = 64
0
2
4
6
0
10
20
0
2
4
6
8
AE
GP
ho
sp
0-17 18-44 45-64 65+ 0-17 18-44 45-64 65+ 0-17 18-44 45-64 65+
age group
pe
rce
nta
ge
of
the
n c
ase
s
The future
▶ Virological confirmation▶ Other diseases▶ Mobile phone app
Other projects elsewhere
