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Based on working documents – refer to final published call text

International Cooperationin Health Research and Life Sciences

Modalities and Topics of next Call

Open Information Day – Brussels, 8 June 2010

Dr Gianpietro van de GoorDirectorate Health, DG Research

European Commission

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Based on working documents – refer to final published call text

International Research Collaborations

Priority for the EU - Opportunity for Researchers

Diseases do not respect political or cultural borders, and affect both poor and rich countriesHealth is a political priority for most countries(rich and poor) “Rich world” diseases (cancer, diabetes, cardivascular diseases, …) also affect developing countries and vice-versa (Malaria, TB, …)Treatments and cures are universal (public good)

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Based on working documents – refer to final published call text

International Research Collaborations

Priority for the EU - Opportunity for Researchers

Access and integration of expertise (people) and know-how (methodologies and technologies)Networking, Division of Tasks, Pooling of resources(knowledge, infrastructures, investments)

Improving health of European citizens and/or increasing competitiveness of European health-related companies

Alignment of efforts on common goals with mutual benefits

Addressing common global health threats (communicable diseases, (re)emerging epidemics, public health systems in disease-endemic countries) and health challenges (MDGs, non-communicable diseases, global health)

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Based on working documents – refer to final published call text

The European Research Area (ERA)

27 EU Member States

+7 Outermost RegionsGuadeloupe, French Guiana, Martinique and Réunion (the four French overseas departments), the Canaries (Spain), and the Azores and Madeira (Portugal)

+12 Associated Countries(the EU neighbourhood countries)Albania, Bosnia and Herzegovina, Croatia, Iceland , Israel, Liechtenstein, FYR of Macedonia, Norway, Republic of Montenegro, Serbia, Switzerland, Turkey

+FP7 Third CountriesOther countries worldwide- can participate in FP7 - some can receive funding(ICPC, incl. BRICS) and othersonly exceptionally (high-incomecountries)

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Based on working documents – refer to final published call text

• Many topics are quite broad / more bottom-up• All topics are open for Third Country Participation:

– An opportunity to involve partners from anywhere in the world– US participation is “unconditional” as in the previous calls

• Some topics targeting Specific World Regions• Some topics calling for Specific International

Cooperation Actions (so-called SICAs) Address specific issues that partner countries face or have a global

character, on the basis of mutual interest and benefit

• Programme-Level Cooperation with specific countries alignment & coordination, i.e. agreement of topics + synchronisation of

parallel calls + networking/collaboration between funded projects

International Research Collaborations

Health Topics & Funding Schemes

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Based on working documents – refer to final published call text

For most instruments (CP-IPs, small/medium CP-FPs):Minimum number of participants: 3 from MS/ASAverage Size: large CP-IPs – €10.7 Mio /17 partners, medium CP-FP - €3.5 Mio / 10 partners, small CP-TP – €3.2 Mio / 8 partnersAverage Third Country Participation: 30% of grants, 8% of participationsAll topics are open for Third Country Participation

But: Specific International Cooperation ActionsMinimum number of participants: 2+2 (2 from MS/AS + 2 from ICPCs)Average Size: CP-SICA - €3.4 Mio / 9 partners (5+4)Third Country Participation: up to 9 from third countries! (4 in average)Third Country Participation is not limited to countries of a target region (if any)!

International Research Collaborations

Minimum requirements & funding

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Based on working documents – refer to final published call text

e.g.: a small- or medium-scale Collaborative Project with a €6m ceiling can involve just 3 or 4 partners for only two years with a budget of €4m.

Flexibility

Some basic rules and guidelines, but:

The size of consortium (beyond min. 3)

The composition of the consortium is for the applicants to decide

The duration of the project (bottom-up)}

International Research Collaborations

Excellence driven research

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Based on working documents – refer to final published call text

Peer Review

Equality, Fairness, Transparency

Excellence - only the bestwill get funded

International Research Collaborations

Evaluation and SelectionBasic Principles

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Based on working documents – refer to final published call text

Bilateral Programme-level Cooperation

EU-NIH Funding Reciprocity

« European Union and NIH collaborate »published by SCIENCE on 14 Nov 2008, Vol 322, page 1048http://www.sciencemag.org/cgi/reprint/322/5904/1049b.pdf

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Based on working documents – refer to final published call text

International Knockout Mouse Consortium(IKMC, 2007) with US, EU, Canada; http://www.knockoutmouse.org/

International Human Microbiome Consortium(IHMC, 2008) with EU, US, Japan, France, Gambia, Australia, Canada (Korea, Ireland); http://www.human-microbiome.org/

International Cancer Genomics Consortium(ICGC, 2008) with US, EU, DE, UK, FR, ES, IT, Canada, China, India, Japan, Australia, http://www.icgc.org/

International Human Epigenome Consortium(IHEC, 2010) with EU, US, Australia, possibly Canada, Japan, China, Singapore, South Koreahttp://www.epigenome-noe.net/, see also the "Human Epigenom Project" at http://www.epigenome.org/index.php

Multilateral/global Programme-level Cooperations

International Research Consortia

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Based on working documents – refer to final published call text

All FP7 areas All Countries Third Countries(Non-EU, Non-AC)

Proposals received(N° of participations)

42’248(237’662)

6’997(14’466)

17%(6%)

Grant Agreements(N° of participations)

6’833(40’729)

958(2117)

14%(5%)

EU funding €12’701 Mio

FP7 HEALTHProposals received(N° of participations)

2315(21’829)

591(1464)

26%(7%)

Grant Agreements(N° of participations)

405(4241)

123(327)

30%(8%)

EU funding €1’606 Mio

International Research Collaborations

Some FP7 Facts & Figures

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Based on working documents – refer to final published call text

International Research Collaborations

Third Country ProjectsAll thematic areas

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Based on working documents – refer to final published call text

International Research Collaborations

Third Country ParticipationFP7 COOPERATION in HEALTH

239

164152

131 136

6243

5847 38 33

4975 75

5832

1734

21 22 1829 22 31

11

6647

33 31 22 20 17 16 15 12 12 11 10 9 8 8 8 7 7 6 6 6 5 5 50

50

100

150

200

250

300Evaluated

Short listed

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Based on working documents – refer to final published call text

• Programme-Level Cooperation with:– Russia: 1.1-3 HTP Proteomics– Brazil: 1.1.4-5 Inflammatory and Autoimmune diseases– India: 2.2.1-4 Neurodegenerative paediatric diseases– India: 2.4.1-3 Cancer from Infectious Agents– Brazil: 3.4-3 Multilateral cooperation in Public Health

• Specific International Cooperation Actions: – 2.1.1-4 Pop. Genetics on Cardio-Metabolic Disorders– 2.3.3-2 Control of Dengue Fever– 2.4.3-4 Obesity and/or Diabetes in Specific Populations– 3.4-1 Reproductive Health and Health Equity

• Other topics of particular international nature: – 2.3.3-1 Zoonotic Viruses– 2.3.3-3 Major Epidemic Outbreaks– 2.3.1-2 Evolution/transfer of AMDR– 3.3-1 Determinants of Health– 3.4-2 Research Capacity

International Research Collaborations

Opportunities in the next Call (WP2011)

2.1.1-1 Human Epigenomics (IHEC) 2.1.1-3 host aspects of inf.diseases 4.1.3- Research Capacity 4.2-1 Paediatric Medicines

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Based on working documents – refer to final published call text

Calls for Proposals, Work Programme (Topics)http://cordis.europa.eu/fp7/health/

National Contact Points (NCPs) - Information & support for applicantshttp://cordis.europa.eu/fp7/health/support_en.html

FP6/FP7 projects databaseshttp://www.lifecompetence.eu/; http://www.healthcompetence.eu/

Partner search toolshttp://www.smesgohealth.org/, http://cordis.europa.eu/fp7/partners_en.html

EU health research websitehttp://ec.europa.eu/research/health/

International Research Collaborations

Information & Support

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Based on working documents – refer to final published call text

Other FP7 opportunitiesfor international cooperation

RTD Career, Training, MobilityMarie Curie International Incoming Fellowships (MC-IIF)http://cordis.europa.eu/fp7/mariecurieactions/iif_en.html

Marie Curie International Outgoing Fellowships (MC-IOF)http://cordis.europa.eu/fp7/mariecurieactions/iof_en.html

International Research Staff Exchange Scheme (IRSES)http://cordis.europa.eu/fp7/mariecurieactions/irses_en.html

Euraxess - Researchers in Motion, One-stop shop for researchers seeking to move to other countries (Job Portal, Mobility Services, Networks)http://ec.europa.eu/euraxess/index.cfm

RTD CapacitiesAccess to Research Infrastructureshttp://ec.europa.eu/research/infrastructures/index_en.cfm?pg=ri_projects_fp7

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Based on working documents – refer to final published call text

Proposed topics for 2011 WPwith an

international dimension or focus

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Based on working documents – refer to final published call text

Biotech, tools & technologies

1.1 – High-throughput research

1.1-3 High-throughput proteomics for human health and disease.Funding scheme: collab. project, max €3m, single-stage, one or more proposals.Target Regions: EU, Eastern Europe & Central Asia (EECA), esp RussiaProgramme-level Cooperation with Russia

1.4-5 New therapeutic approaches in chronic inflammatory and autoimmune diseases. Funding scheme: collab. project, max €3m, single-stage, one or more proposalsProgramme-level Cooperation with Brazil

Int

1.4 – Innovative therapeutic approaches and interventions

Int

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Based on working documents – refer to final published call text

Translating research for health

2.1.1 – large-scale data-gathering:

2.1.1-1 High impact initiative on the human epigenome. Funding scheme: collab. project, max €30m, single-stage, max one proposal.Cooperation with Int. Human Epigenomics Consortium (IHEC)

2.1.1-3 Large-scale genomics approaches to identify host determinants of infectious diseases. Funding scheme: collab. project, max €12m, single-stage, max one proposal.

2.1.1-4 Population genetic studies on cardio-metabolic disorders in EU/AC and EECA populations. Funding scheme: Specific International Cooperation Action (SICA), collab. project, max €6m, single-stage, max one proposal.Target Regions: EU/AC, Eastern European & Central Asian Countries (EECA)

Int

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Based on working documents – refer to final published call text

Translating research for health

2.2.1 – Research on the Brain and related diseases, human development and ageing:

2.2.1-4 Creating clinical and molecular tools for experi-mental therapy of paediatric neurodegenerative disorders causing childhood dementia in Europe and India. Funding scheme: collab. project, max €3m, single-stage, one or more proposals.Target Regions: EU & IndiaProgramme-level cooperation with India

2.3-1 Anti-microbial drug resistance

2.3.1-2 Multi-disciplinary research on the evolution and transfer of antibiotic resistance. Funding scheme: collab. project, max €12m, single-stage, max one proposal.

Int

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Based on working documents – refer to final published call text

Translating research for health

2.3.3 – Potentially new and re-emerging epidemics

2.3.3-1 Identification of factors promoting the emergence of pathogens with human pandemic potential from pathogens with a zoonotic background and related prevention strategies. Funding scheme: collab. project, max €12m, two-stage, max one proposal.

2.3.3-2 Comprehensive control of Dengue fever under changing climatic conditions.Funding scheme: SICA - collab. project, max €6m, single-stage, one or more proposalsTarget regions: Latin America & Asia

2.3.3-3 Development of an evidence-based behavioural and communication package to respond to major epidemic outbreaks.Funding scheme: collab. project, max €2m, 2-stage, one or more proposals.

Int

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Based on working documents – refer to final published call text

Translating research for health

2.4.1 – Cancer

2.4.1-3 Epidemiology and aetiology of infection-related cancersFunding scheme: collab. project, max €3m, 1-stage, one or more proposals.Programme-level cooperation with India

Int

2.4.3 – Diabetes and obesity

2.4.3-4 Genetic and environmental factors in obesity and/or diabetes in specific populations. Funding scheme: SICA – collab. project, max €3m, 2-stage, one or more proposals.Target regions: Africa, Asia, Latin America, Mediterranean countriesProgramme-level cooperation with Mexico, Australia, New Zealand

Int

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Based on working documents – refer to final published call text

Translating research for health

2.3.4 – Neglected infectious diseases

Closed in 2011

2.3.2 – HIV/AIDS, malaria and tuberculosis

Closed in 2011

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Based on working documents – refer to final published call text

Optimising delivery of healthcare

3.3 – Health promotion

3.3-1 Developing methodologies to reduce inequities in the determinants of health. Funding scheme: collab. project, max €3m, 2-stage, one or more proposals.

3.4 – International public health & health systems

3.4-1 Development and assessment of comprehensive and integrated interventions and programmes to improve repro-ductive health and health equity. Funding scheme: SICA - collab. project, max €3m, single-stage, one or more proposalsTarget Region: ICPC (low- & middle-income countries)

Int

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Based on working documents – refer to final published call text

Optimising delivery of healthcare

3.4 – International public health & health systems

3.4-2 Building sustainable capacity for research for health and its social determinants in low and & middle income countries. Funding scheme: CA, max €2m, single-stage, one or more proposals.Target Region: ICPC (low- & middle-income countries)

3.4-3 Multilateral cooperation between Europe, Africa and Latin America on public health and health services research. Funding scheme: CA, max €2m, single-stage, max one proposal.Target Regions: EU, Africa, BrazilProgramme-level cooperation with Brazil

Int

Int

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Based on working documents – refer to final published call text

Actions across the Health theme4.1 – Coordination and support actions across the theme

4.1-3 Linking EU and Latin American policy-making institutions in the field of health research.Funding scheme: CA, max €2m, single-stage, max one proposal.Target Region: EU & Latin America

4.2 – Responding to EU Policy needs

4.2-1 Investigator-driven clinical trials on off-patent medicines for children. Funding scheme: collab. project, max €6m, single-stage, one or more proposals.

CT

Int