NEUROPHARMACO LOGY REVIEW LINA PIECH, PHARM.D., BCPS ADVOCATE CHRIST MEDICAL CENTER MARCH 13, 2015.
Interdisciplinary Collaboration for Problem Solving: the pathway to better patient care Molly Adams,...
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Transcript of Interdisciplinary Collaboration for Problem Solving: the pathway to better patient care Molly Adams,...
![Page 1: Interdisciplinary Collaboration for Problem Solving: the pathway to better patient care Molly Adams, Pharm.D., BCPS Brad Wright, Pharm.D., BCPS Greg Rutecki,](https://reader035.fdocuments.us/reader035/viewer/2022080916/56649e735503460f94b72da8/html5/thumbnails/1.jpg)
Interdisciplinary Collaboration for Problem Solving: the pathway to
better patient care
Molly Adams, Pharm.D., BCPSBrad Wright, Pharm.D., BCPS
Greg Rutecki, MD
![Page 2: Interdisciplinary Collaboration for Problem Solving: the pathway to better patient care Molly Adams, Pharm.D., BCPS Brad Wright, Pharm.D., BCPS Greg Rutecki,](https://reader035.fdocuments.us/reader035/viewer/2022080916/56649e735503460f94b72da8/html5/thumbnails/2.jpg)
Objectives Provide an example Define Collaboration Describe hypertensive crises Examine treatment options Explain Problem Solving via Quality Assurance Evaluate Stakeholder Perspectives
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Our Example Identification of a problem
Hospital management of hypertensive crises Problem 1: Identifying patients experiencing
hypertensive urgencies/emergencies Problem 2: Choice of agent to treat the hypertensive
emergency/urgency appropriately
Team approach Put together a team to research the problem and
solution Pharmacist-physician collaboration
Diagnosis – Dr. Rutecki Treatment – Drs. Adams, Karwa, and Wright
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Our Example Literature evaluation
Use evidence-based medicine to determine best diagnosis and treatment strategies
Pharmacy team Looked at guidelines, reviews, as well as trials
comparing drugs used in the treatment of hypertensive crises
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Hypertensive Crises - Background Chronic hypertension is one of the most
common medical conditions in the United States Affects ~30% of the population Significant risk factor for cardiovascular,
cerebrovascular and renal problems Acute elevations in BP may result in acute
damage to organs and significant morbidity or mortality
Patients with acutely elevated blood pressure (BP) are considered to be experiencing a hypertensive crisis
Usually defined as a BP >179/109
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End Organ Damage The Heart:
Acute myocardial infarction, acute coronary syndrome , acute heart failure.
During Pregnancy: Pre-eclampsia, eclampsia, or “HELLP” syndrome (Hemolytic Anemia,
Elevated Liver Enzymes & Low Platelets).
Blood vessels: Injury to the aorta - aortic dissection.
The Brain/Central Nervous System: Strokes, subarachnoid hemorrhage, and hypertensive encephalopathy
The kidneys: Acute renal failure
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Emergency vs. Urgency Hypertensive crises can be further classified
into hypertensive emergencies or urgencies. Hypertensive emergency – severe elevation in
BP accompanied by end organ damage Damage to the brain, heart, eyes, or kidnes
Hypertensive urgency – severe elevation in BP not accompanied by end organ damage
Distinguishing between urgency and emergency is important Treatment differs for the two conditions and
therefore the most appropriate treatment plan is based on diagnosis
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Emergency vs. Urgency treatment Urgency
Goal of treatment - reduce BP gradually over 24-48 hours
Significant morbidity is associated with too rapid a reduction in BP
Select oral combination medications to lower BP Most optimal agent should have:
A rapid onset Few adverse effects Absence of excessive hypotension Be able to be monitored
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Emergency vs urgency treatment Emergency -
Goal of treatment – decrease BP immediately Slow and controlled decrease need to prevent organ
hypoperfusion, morbidity or mortality The patient should be admitted to the Intensive
Care Unit (ICU) Treat with an intravenous continuous infusion of
an antihypertensive agent that is titratable, short-acting and able to be monitored Drug of choice depends on the clinical scenario Avoid oral, sublingual, and intramuscular (IM) routes
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Causes Majority of patients have been diagnosed with
chronic hypertension Many are poorly controlled on current therapy Many are non-adherent to current regimen
>50% of patients
Drug Use Prescription drugs
Drug interactions Clonidine withdrawal
OTC Herbal Illicit drugs
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Other causes Endocrine disorders Kidney disorders CNS injury Unknown
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Diagnosis Should be prompt to avoid end-organ damage Thorough medical and medication history Confirmation of BP in both arms Identify end-organ damage
Pulse in extremeties Auscultate lungs and hear Neurologic exam Fundoscopic exam Cardiac exam
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Management - Hypertensive urgency Optimal agents should have a rapid onset, few
adverse effects, absence of excessive hypotension, and be able to be monitored
Oral drugs used to treat hypertensive urgencies Clonidine Captopril Patient’s home regimen
Oral drugs not used to treat hypertensive urgencies Nifedipine
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Management – Hypertensive Emergency Same basic treatment principles as hypertensive urgency
Added goal is to prevent progression of end organ damage Intravenous medications for treatment of hypertensive
crisis Clevidipine Nicardipine Esmolol Labetolol fenoldapam Phentolamine Enalaprilat
Intravenous Medications that should be used with caution Nitroprusside Nitroglycerin Hydralazine
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Quality Assurance Steps Identify the Problem Collect information for analysis Evaluate literature for comparison and
suggestions on improvement Select a method for improvement
Education Order sets and protocols System changes
Re-evaluate after a time to verify improvements effective
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Problem Recognition Identify through anecdotal reports Care provider questions Case reports and series Barriers to optimal patient care
Ineffective results in patient outcomes Time management issues Adverse outcomes
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Inpatient Improvement Methods Drug Utilization Evaluations (DUEs) Pharmacy and Therapeutics Committees
Protocols Order Sets
Teaching In-services Nursing Pharmacy Physician
Workflow adjustments
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Collaboration Definition
To work, one with another; cooperate To work with another or others on a joint project
Collaboration occurs when no one profession or organization can achieve its goals without building upon its interdependence with others
Requires that all team members want to work together to accomplish a common goal Each team member brings a unique perspective or
expertise All work together to improve a problem
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Collaboration – Our example A problem with was noted with the pharmaceutical
and medical management of sever hypertension A team was formed with each team member
focused on one goal Goal – Improve the management of hypertensive crises
Each team member brought unique expertise Physicians – Diagnosis of hypertensive crises Pharmacy – Medications used in the inpatient and
outpatient settings In the end each team member brought specific info
that when combined improved the treatment of hypertensive crises
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Collaboration – Other examples Diabetes Management
University of Buffalo Hypertension Management
Inpatient - Midwest Veterans Affairs Medical Center
Outpatient – Iowa City, Iowa Heart Failure Management
PHARM Study