Integumentary Systeggggggggggggfgvhhhhhhhhhhhhhm W-o Quiz

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    Integumentary System

    CMM News

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    Functions Of The IntegumentCushionsand insulates deeper organs

    Protectsbody from abrasion, trauma, chemicapathogens, temperature extremes and UV rays

    Excretion and secretion

    Contains sensory receptorsassociated with n

    endingsSynthesis and storage of nutrients (vitamin D3)

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    Integumen

    System Largest bo

    Skin Hair

    Nails

    Glands

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    Integumentar

    Epidermis

    Outermost laye

    the skin Dermis

    Contains collag

    Supports nervevascular netwo

    Subcutaneous

    Fat and loose

    connective tiss

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    Structure Epidermis: Thin avascular

    superficial laye

    Nourished bloovessels (dermi

    Replaced ever

    days

    Types of cells:

    Melanocyt

    keratinocy

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    Integumentary StructuresComponents of the Integumentary S

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    Skin Structures

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    The Epidermis- Four Main Cell Melanocytes - found in basal

    layer, manufacture and secrete

    pigment Merkel cells - basal layer,attached to sensory nerveendings

    Keratinocytes Arise fromdeepest layer of epidermis to

    stratum spinosum Produce keratin a toughfibrous protein

    Produce antibodiesandenzymes

    Keratinocytes are dead at skin'ssurface

    Langerhans cells - stratum

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    Stratified squamous epithelium

    Several distinct cell layers

    Thick skinfive layers on palms and soles

    Thin skinfour layers on rest of body

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    Layers of The Epidermis

    Stratum corneum Most superficial layer

    Dead, flattened(squamous) cells

    Abundant keratin -Keratinized(cornified)tough, water-resistantprotein

    Protects skin againstabrasion andpenetration

    Stratum lucidum(clearlayer) Occurs only in thick skin

    palms and soles

    Composed of a few

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    Layers of The Epidermis

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    Layers of the Epidermis

    Stratum basale

    Deepest layer of epidermis Attached to underlying

    dermis

    Stem cells actively divide

    Merkel cells associated

    with sensory nerve ending Melanocytes secrete the

    pigment melanin

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    Epidermal Cells and Layers of the Epiderm

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    Sources of Skin Color

    Melanocytes Make melanin from tyrosine

    Melanin provides UVprotection

    Gives reddish-brown tobrown-black color

    Carotene Contributes orange-yellow

    color Provided from diet (carrots

    and tomatoes)

    Hemoglobin - bloodpigment Caucasian skin contains

    little melanin

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    Dermis

    Richly supplied with nerves (sensory receptors), blood vessels, lymphatic vessels,

    sebaceous glands derived from the epidermis. Contains two layers: papillary and

    Papillary regionis composed of loose areolar connective tissue. This is n

    fingerlike projections called papillae, that extend toward the epidermis and c

    terminal networks of blood capillaries or tactile Meissner's corpuscles.

    Reticular layeris the deep layer of the dermis and consists of the dense irre

    tissue. Within the reticular region are the roots of the hair, sebaceous glands

    receptors, nails, and blood vessels.

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    Dermal Components

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    Subcutaneous Layer - Hypodermis

    Composed of loose connective tissue - areolar and adipose

    Stabilizes skin position

    Loosely attached to dermis

    Loosely attached to muscle

    Contains many fat cells

    Provides thermal insulation

    Cushions underlying organs

    Safely receives hypodermicneedles

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    Hair Filamentous strands of dead

    keratinized cellsproduced by hairfollicles

    Contains hard keratin which is tougherand more durable than soft keratin ofthe skin

    Chief parts of a hair

    Root imbedded in the skin

    Shaft projects above skin's surface

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    Hair Function and Distribution Functions of hair include:

    Helping to maintain warmth

    Alerting the body to presence of insects on the skin

    Guarding the scalp against physical trauma, heat loss, and su

    Hair is distributed over the entire skin surface except

    Palms, soles, and lips

    Nipples and portions of the external genitalia

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    Glands

    There are there exocrine (conts ducts) glands: sebaceous,

    sudoriferous and;

    These glands secrete their contents to the exterior unlike end

    secrete their contents directly into blood.

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    Sebaceous Glands (oil glands) Occur over entire body - Except palms and soles

    Simple alveolar glands

    Holocrine secretion entire cell breaks up to form secretion

    Secretes an oily substance called sebum

    Most are associated with a hair follicle

    Functions of sebum

    Softens and lubricates hair and skin

    Skin waterproofing

    Collects dirt

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    Sudoriferous Glands (Sweat) Two types:

    Eccrine (Merocrine) Most abundant sweat gland

    True sweat

    99% water with some salts

    Contains traces of metabolic wastes ~ 2%

    urea

    Role in thermoregulation

    Widely present in skin (up to 500/cm2)

    Apocrine

    Odorous secretion

    Absent before puberty

    Present in axillary, areolar, anal and genital

    areas

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    Ceruminous Gland

    specialized sudoriferous glands

    found only in the external auditory canal where they secrete

    (earwax)

    Cerumenis also an insect repellant and keeps the eardrum f

    out.

    However, an excess of this may cause blockage.

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    Nails Scalelike modification of epidermis

    made of hard keratin

    Parts of the nail

    Free edge

    Body - dense mass of keratinizedcells

    Root

    Nail folds

    Eponychium cuticle

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    Skin Injury and Repair

    Four Stages in Skin Healing1. Hemostasis

    a. Blood flow increases

    b. Phagocytes attracted

    2. Inflammation

    3. Proliferative Stage4. Remodeling

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    Hemostasis

    This process is the stoppage of bleeding

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    Hemostasis

    A special protein known as Fibrincross links on top of

    which prevents blood from flowing out and pathogen

    coming in

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    Inflammation

    Shows sign of redness and swelling

    Phagocytosis

    Vasodilation

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    Inflammation: Phagocytosis

    Occurs when the white blood cells known as Macroph

    consume and destroy bacteria

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    Inflammation: Vasodilation

    Expansion of the blood vessels

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    Proliferative Stage

    Entry of Fibroblast Cells

    Collagen Deposition

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    Proliferative Stage: Collagen Deposition

    The fibroblast cell release collagen which forms conne

    tissue to replace fibrin

    Dermis contacts to close the wound

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    Remodeling

    Collagen is then rearranged and converted to spe

    Skin slowly return to its original state as best as it

    Wound may then just end up as a scar

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    Burns

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    Effects of UV Radiation

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    Types and Growth of Hair

    Vellus hairs

    Body hairs of women and children

    Terminal hairs

    Hair of scalp

    Axillary and pubic area (at puberty)

    Hair thinning and baldness Due to aging

    Male pattern baldness

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    Skin Cancer

    Melanocytesare the

    skin cells that have

    clustered thus

    forming a mole. They

    are also melanin

    producing cells

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    Skin throughout life

    Fetal skin

    Well formed after the fourth month At 5-6 months the fetus is covered with lanugo (downy h

    Fetal sebaceous glands produce vernix caseosa

    Middle to old age

    Skin thins and becomes less elastic

    Shows harmful effects of environmental damage Skin inflammations become more common

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    QUIZ!