Inside Cover: Improved 2,4-Diarylthiazole-Based Antiprion Agents: Switching the Sense of the Amide...
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The inside cover picture shows the development of thiazole-based antiprion agents from 5-amino compounds (top left) towards the discovery of a new lead compound bearing a 5-carboxamide sub- stituent (bottom left). The background depicts spongiotic brain tissue from a case of variant CJD, as a reminder of the pressing need for progress in treating these devastating neurological disorders (Photo source: Public Image Health Library; Photo credit: S. Zaki, W.-J. Shieh). For more information, see the Full Paper by M. J. Thompson et al. on p. 1476 ff.
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Transcript of Inside Cover: Improved 2,4-Diarylthiazole-Based Antiprion Agents: Switching the Sense of the Amide...
The inside cover picture shows the development of thiazole-based antiprion agents from 5-aminocompounds (top left) towards the discovery of a new lead compound bearing a 5-carboxamide sub-stituent (bottom left). The background depicts spongiotic brain tissue from a case of variant CJD, as areminder of the pressing need for progress in treating these devastating neurological disorders (Photosource: Public Image Health Library; Photo credit: S. Zaki, W.-J. Shieh). For more information, see theFull Paper by M. J. Thompson et al. on p. 1476 ff.
Inside Cover
Mark J. Thompson*, Jennifer C. Louth, Gemma K. Greenwood,Fiona J. Sorrell, Sandra G. Knight, Nathan B. P. Adams, andBeining Chen
The inside cover picture shows the development of thiazole-based antiprion agentsfrom 5-amino compounds (top left) towards the discovery of a new lead compoundbearing a 5-carboxamide substituent (bottom left). The background depicts spongioticbrain tissue from a case of variant CJD, as a reminder of the pressing need for progressin treating these devastating neurological disorders (Photo source: Public Image HealthLibrary; Photo credit : S. Zaki, W.-J. Shieh). For more information, see the Full Paper byM. J. Thompson et al. on p. 1476 ff.
