Innovations in Healthcare - US Chamber of Commerce

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Innovations in Healthcare Key Drivers of Change October 18, 2016 US Chamber of Commerce Washington, DC 1 Contents are proprietary and confidential.

Transcript of Innovations in Healthcare - US Chamber of Commerce

Page 1: Innovations in Healthcare - US Chamber of Commerce

Innovations in Healthcare

Key Drivers of Change

October 18, 2016US Chamber of Commerce

Washington, DC

1 Contents are proprietary and confidential.

Page 2: Innovations in Healthcare - US Chamber of Commerce

Three Major Drivers of Innovation

SCIENCEBIG DATA AI, MACHINE LEARNING & NEURAL NETWORKS

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The Information Genome

Everything we do, inside or out, can be monitored

Our bodies and all we do are the next frontier for

search

Patterns = Products Personalization becomes mainstream

Our intellectual capital is magnified when we

enable software to learn on its own

Pattern-based learning will lead to more

personalized solutions

The combination of science and technology

opens up new thinking for treatment, services and

solutions

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And often require previously unrelated areas to merge

Innovation eras take time to develop

The WebFirst plan for WWW in 1989

The genome meets its match with AI

Precision of knowledge powers rare disease innovation

Health data attracts technology entrepreneurs

Tim

e

Artificial Intelligence1952-56 timeframe

Human Genome ProjectLaunched 1990Completed 2003

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A look at our future is forming……

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What if we combine high volume semiconductor and pharmaceutical

technology?

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An ingestible sensor the size of a grain of sand, a patch, an app and a provider portal are combined

We can track patients thousands of miles away, see if they took the medicine, what their

pharmacokinetics are and where it was made

This is Proteus Digital Health

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What if we could figure out how to edit disease?

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The CRISPR–Cas9 system

Treat and edit diseaseTarget and study particular DNA sequences

Send proteins to precise DNA targets to turn genes on or off

Bayer & CRISPR Therapeutics form JV

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What new medical disciplines will form as a result of technology and healthcare

converging?

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Bioelectronics medicineA new discipline combining molecular medicine, neurophysiology, biomedical

engineering, deciphering and manipulating the electrical signal produced by the nervous system to communicate information

Neural bypass technology allowed a paralyzed person, for the first time, to regain movement through the use of a brain implant. Therapies can be developed that work

by recording, stimulating, and blocking neural signaling

Chad Bouton and The Feinstein Institute for Medical Research

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What is the promise of virtual reality in health?

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Train physicians anywhere in the world Distract burn victims via VR and decrease their

painHelp veterans learn to deal with PTSD

It is a matter of our applied imagination

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What if we can unlock the power of our immune system to fight disease and replace more toxic therapies?

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The power of Immunotherapy

Anti PD-1 immunotherapy blocks the pathway so our immune system can do its job

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How can technology and machines improve what humans do?

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Robotic-assisted minimally invasive surgery guided by MDs

Intuitive Surgical

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What new minds are tackling health issues?

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Jeff Huber (Google) joins newly formed Grail, a joint venture of Illumina, Jeff Bezos, Bill Gates

& Google Ventures

Goal: develop a proactive cancer-detecting blood test to identify the tiny bits of cancer DNA that are hanging out in our blood but are currently

undetectable.

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What if all or most of our health data could be integrated?

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The equivalent of our data immune systemWill we unlock its power?

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Personalization is being redefined

Your body is an untapped data sourceData, AI and robotics are drivers of innovation

Any disease or disorder is fair game today

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The United States of America has an unprecedented opportunity to drive a new era

of innovation

Technology and Healthcare partnerships will lead to exponential advance for the next few

decades

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Innovation will accelerate at a greater pace in the years ahead

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Organizations will struggle to keep up…..Martec’s Law

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Political and business interests must align around improving the health of all people

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Our role in supporting innovatorsWill we create an environment that can accelerate innovation, transform health outcomes and drive our economy?

Clarity of Rules

How we regulate

Ambiguity stifles investment

Clarity of Payment

Return on investment

If payment is unclear, entrepreneurs find other things to innovate

Ability to Learn Together

The Role of FDA

FDA and innovators should commit to learn together, stay on top of what’s next and evolve thinking at the same pace

Ability to Evolve Together

New regulations

If we evolve together, we save years, even decades of misaligned regulatory standards and innovative advances

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Everyone is counting on us to succeed! The journey continues….

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