Information session: SUMMER RESEARCH OPPORTUNITIES in … · Jodi Schottenfeld-Roames I am...
Transcript of Information session: SUMMER RESEARCH OPPORTUNITIES in … · Jodi Schottenfeld-Roames I am...
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Information session: SUMMER RESEARCH OPPORTUNITIES
in BIOLOGY • on- and off-campus
• funding sources • application procedures
Mon, Nov 16th 4:30 – 5:30pm
SC101 Please consult individual programs for
deadlines: Deadlines are as early as January and, at the latest, early March
Swarthmore deadline: February 10, 2016 http://www.swarthmore.edu/student-life/summer-research-opportunities.xml
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!!
SUMMER!RESEARCH!OPPORTUNITIES!
Deadline!February!10,!2016!!• ApplicaBon!period!opens!January!19!!
• Apply!through!mySwarthmore.!• ApplicaBon!informaBon!at!link!below.!• Link!can!be!found!on!The!Dash.!• Deadline!Weds!Feb!10!at!11:59:59!pm.!
OnTcampus!or!!OffTcampus!!funding!available!
www.swarthmore.edu/studentTlife/summerTresearchTopportuniBes.xml!
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Summer fellowships for research projects with NSE faculty members: deadline Feb 10, 2016 • Division of Natural Sciences & Engineering (NSE)
• Howard Hughes Medical Institute (HHMI) grant – Including some fellowships for 1st-year or 2nd-year students
who are either first-generation college students or members of groups that are underrepresented in science.
• Biology Department Funds for Field Research
• Individual faculty research grants Contact faculty members whom you admire to explore
your interests! !
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Summer fellowships for projects at another university or research institute:
deadline Feb 10, 2016 • Many summer research programs at universities
across the country – see Biology Dept website > Opportunities for Students > Research
Opportunities > Summer Research Elsewhere
• Biology Department Funds for Field Research
• Howard Hughes Medical Institute (HHMI) grant – Applicants must explain and justify the project. Applications must be
accompanied by two letters: one from the off-campus researcher who will directly mentor the student's project and one from a Swarthmore faculty member in the NSE Division who knows the student, has reviewed the proposal, and will serve as on-campus liaison. VERY COMPETITIVE
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How to apply? Talk to faculty EARLY – before the end of fall semester
• How to find a faculty research mentor – Someone who has taught you in course/lab Are their interests compatible with your own, e.g.,
biological questions posed techniques / experimental approaches
• Consider your qualifications
experience (and performance) in courses interest – how is that demonstrated? initiative and commitment
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Timeline: start early, don’t procrastinate
• Meet with faculty before you leave for winter break • Line up people who will write letters of
recommendation • Give each recommender a copy of your resume • Apply as soon as you return for 2016
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Handout • FAQs
http://www.swarthmore.edu/summer-research-opportunities/frequently-asked-questions
• IRB: Human Subject Research – extra paperwork – allow for extra time!!!!!
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http://www.swarthmore.edu/irb!!IRB= institutional Review Board!
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Student Research Panel Ask STUDENT RESEARCHERS about their
experiences in an informal setting!
Hosted by the Swarthmore Biology Club Interested but can’t attend or have questions? email kpalmqu1
Tuesday, November 24th 4:30-5:30PM Science Center 105
What%is%the%difference%between%independent%research%and%research%through%a%program?%
What%are%good%ways%of%choosing%research%labs?%
What%kind%of%future%is%a%summer%in%research%
se:ng%me%up%for?%
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Some students who did research on or off campus – how did they find opportunities?
• Karl Palmquist • Shaina Lu • Casey Simon-Plumb • Maxine Annoh • Chris Bourne • Gurrein Madan • Jonathan White
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Research experience – with Biology faculty
• Biology faculty who stay here on campus
• Biology faculty who go elsewhere for the summer (field work)
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Biology Faculty Baugh Davidson Formica Hiebert Burch Mayack Nichols Schottenfeld-Roames Siwicki Vallen
Will help students find opportunities elsewhere:
Kaplinsky Machado Merz Vollmer
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Alex Baugh Animal communication
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endocrinology%development%
ecology%
of%varia<on%
percep<on%
Baugh%Lab%
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96%%4%%
quesBon:%why%are%[some]%females%so%choosy?%method:%female%frog%phonotaxis%mate%choice%tes<ng%
%%%%%%%%%20Ipulse%call%%%%%%%%%%%%%%%%%%%%%%35Ipulse%call%%%%%%%%%%%%%
hypothesis:%differences%in%acute%reproduc<ve%status%of%females%generates%individual%differences%in%choosiness%
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18!
• development%of%individual%differences%in%
physiology,%%behavior%and%life%history%
• real%<me%decision%making%
%%%
decision
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Brad Davidson
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Davidson Lab: Heart development in a simple chordate
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+%Mesp%%%%%%%%%%GFP%
FoxF%5�% RFP%
Visual!readout!of!heart!cell!idenBty!+!targeted!manipulaBons…!
2 heart precursors +%Mesp%%%%%%%%%%dnFGFR%
No heart cells
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Davidson Lab: Heart development in a simple chordate Cell Behavior
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Comparative approach (Swarthmore Genomes)!!Ciona intestinalis !
2. FoxF-RFP + Esc-GFP!Corella: Esc-GFP + FoxF-RFP!
Corella willmeriana!
~200!mya!
Ciona savignyi!
Phallusia mammillata!
Corella inflata!
Phallusia fumigata!
Halocynthia roretzi!Halocynthia aurantium!Oikopleura dioica!
~300 mya!
~500 mya!
Boltenia villosa!Boltenia echinata !
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Vince Formica – The evolution of social networks
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Undisturbed DisturbedTime Period 1 Time Period 2 Time Period 1 Time Period 2
Population 1
Population 3
Population 4
Population 2
Population 5
Population 7
Population 8
Population 6
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Students working with Vince live at 4000ft at the Mountain Lake Biology Station from Early June – Mid August.
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Rufous%hummingbird%
Hummingbird gut microbes Amy Vollmer Sara Hiebert Burch
summer/breeding!winter!migration!
Rufous hummingbirds migrate long distances every spring and fall
~2500%miles%
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Rufous hummingbird
Hummingbird gut microbes Amy Vollmer Sara Hiebert Burch
• To accomplish these long flights, rufous hummingbirds fatten
• During the fall migration, they may almost double their body mass by putting on fat!
• At the end of migration, they return to the lean state even if given unlimited food
migratory pre-migratory post-migratory
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Hummingbird gut microbes Amy Vollmer Sara Hiebert Burch
• In mammals (including humans), obese individuals have different gut microbes than lean individuals
• Microbes transplanted from the gut of an obese individual make a lean individual obese
hUps://srxa.files.wordpress.com/2012/04/obeseImouse.jpg%hUp://www.drfranklipman.com/images/2013/06/Microbiome.jpg%%
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Hummingbird gut microbes Amy Vollmer Sara Hiebert Burch
QUESTION: Are changes in gut microbes also involved in the natural fattening cycle of rufous hummingbirds?
Field work • Capturing hummingbirds • Collecting anatomical and physiological data • Collecting urine and fecal samples (they’re small!)
Lab work: • Using new techniques to identify bacteria • Determining relative abundance
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Nick Kaplinsky Plant developmental genetics
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Structure ! function
hUp://www.autoblog.com/2012/04/09/mythbustersItestsItheIsquareIwheelItheory/%
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http://upload.wikimedia.org/wikipedia/commons/a/a9/Protein_folding.png
Proteins unfold at high temperatures ! loss of function
Normal temperature Folded correctly
Functional
High temperature Unfolded
Non- functional
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Small Heat Shock Protein (sHSP) function
http://dx.doi.org/10.1016/j.tibs.2011.11.005
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Regulation of the heat shock response
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• 1.%Understanding%the%regulatory%mechanisms%involved%in%the%evolu<on%of%social%behavior%
• How%is%appe<te%and%energe<c%state%of%the%honeybee%regulated?%
• How%does%the%response%of%hunger%vary%across%levels%of%sociality%and%does%it%play%a%role%in%the%evolu<on%of%social%behavior?%
Main%research%themes%
Osmia%bee%(solitary)%
Bumble%bee%(semiIsocial)%
S<ngless%bee%(social)%
Orchid%bee%
(solitary)%
Asian%honeybee%(social)%
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Main%research%themes%
2.%Improve%honeybee%health%
• Understand%the%behavioral%and%physiological%effects%of%honeybee%diseases%(Nosema)%
• Establish%indicators%of%healthy%and%diseased%honeybee%hives%by%the%vola<les%they%produce%
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The%Liz%Nichols%Lab%%Environmental%Change%and%Conserva<on%
Project!1.!InfecBon!and!!biodiversityTecosystem!funcBon!(BEF)!
• ObjecBves:!– Study%how%infec<on%shapes%biodiversityIecosystem%func<on%(BEF)%
rela<onships%through%quan<fy%varia<on%in%ecological%func<ons%aUributed%to%altered%behavior%due%to%helminth%infec<ons.%
• Data:!Exis<ng%data%from%Brazil’s%Atlan<c%Forest%• AcBviBes:%
– Address%conceptually%important%ques<ons%using%preIexis<ng%field%data.%
– Pursue%methodological%and%analy<cal%advances%in%BEF%research.%
– Collect%new%experimental%data%if%need%be.%%
• AddiBonal!collaborators:!!– Universidade%de%São%Paulo’s%Landscape%Ecology%and%Conserva<on%
Lab,%Lancaster%University’s%Insect%Parasite%and%Ecology%Group%
• Recent!example:!%– Gregory,%N.,%Gómez,%A.,%Oliveira,%T.,%Nichols,%E.%(2015).%Big%dung%
beetles%dig%deeper:%traitIbased%consequences%for%faecal%parasite%transmission.%Int.%J.%Parasitology.%45:101I105%
Project!2.!Cascading!impacts!of!mammal!hunBng:!a!metaTanalysis!!
• ObjecBve:!– Conduct%a%global%metaIanalysis%on%cascading%impacts%of%
mammal%hun<ng%on%dung%beetles.%
• Data:!Exis<ng%data%from%Brazil,%Peru,%Panama%&%West%Africa%
• AcBviBes:!– Address%conceptually%important%ques<ons%using%preIexis<ng%
field%data%%– Pursue%conceptual%and%analy<cal%advances%in%trophic%cascade%
research%
• AddiBonal!collaborators:!!– Universidade%Estadual%de%São%Paulo%(UNESP),%Conserva<on%
Interna<onal%(Washington%DC),%University%of%East%Anglia%(UK).%
• Recent!example:!%– Nichols,%E,%et%al.%(2013).%HumanIinduced%trophic%cascades%
along%the%fecal%detritus%pathway.%PLOS%ONE%8:e75819%
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Jodi Schottenfeld-Roames I am interested in understanding how branched, tubular organs (such as our vascular system) form. To study this, I utilize the Drosophila tracheal system, the respiratory organ of the fruit fly, as a model system.
I analyze mutant flies to learn about the genes required for tube formation This is a SINGLE
tracheal terminal cell. (just one cell !) It forms beautiful branched extensions, like neurons, but with each branch hollowing out to form a tube that carries oxygen throughout the fly.
So far my has found roles for: The cytoskeleton Polarity complexes Membrane trafficking during tubulogenesis.
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Neurobiology of Drosophila Courtship Behavior!
" Genetically programmed XX = females
XY = males
" Modified by experience – Short-term memory - males become less active courters
after repeated experience with unreceptive females.
What brain structures and molecules are responsible for this memory?!
How do genes produce sexually dimorphic wiring of brain circuits?!
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Opportuni<es%elsewhere:%%NSF%REU%sites%hUps://www.nsf.gov/crssprgm/reu/reu_search.jsp%
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Systems%Biology%at%Harvard%hUp://sysbio.harvard.edu/summerIinternship%%
Agreat%way%for%undergrads%to%get%research%experience%and%learn%a%bit%more%about%different%graduate%schools.%%%%
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Searched%for%“Biology%summer%internships”%
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Every%email%Biology%chair%receives%regarding%summer%internships%
• Sent%to%Career%Services%• Posted%on%Biology%site%
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Mo<va<on%for%Research%• Authen<c%(not%just%‘checking%a%box’)%• Investment%of%<me,%resources,%effort%• Being%part%of%a%culture%of%research%
– Summer%mee<ngs,%social%events%• Outcomes%–%results%to%present/publish,%enrichment%of%your%research%experience,%mentor,%leUer%of%recommenda<on%
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Research requires a strong and sustained commitment
• It’s not graded, but….it requires responsibility, initiative, maturity:
• Experience • Results, records • Posters, papers • Letter of recommendation (give us good
material)
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Talk to faculty before your leave for the holidays • about letters of recommendation • about a research project in his/her lab
Some faculty require that you take a course with them
prior to considering you for a position in the research lab • faculty�s familiarity with you, your work ethic • your familiarity with basic techniques, etc.
E-mail and suggest 3 possible 30 minute meeting times
DEADLINES – they are your responsibility
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Requesting letters of recommendation
• Ask the appropriate person – Someone who has experience teaching you or
working with you in a laboratory situation • Give the person at least 3 weeks for the first letter;
as much time as possible for subsequent letters – a spreadsheet with all programs, deadlines,
whether the letter should be submitted online or sent through the mail, or email attachment
– To whom letter should be addressed