Impaired Consciousness in Focal Seizures: Network Mechanisms and Treatment … · 2017-01-17 ·...

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Hal Blumenfeld, MD, PhD Impaired Consciousness in Focal Seizures: Network Mechanisms and Treatment with Deep Brain Stimulation Tuesday, January 31, 2017 9.00-10:00 am The Chan Centre Auditorium, CFRI 938 West 28th Avenue, Vancouver, BC CURE (Citizens United for Research in Epilepsy) is a 501(c)3 dedicated to <inding a cure for epilepsy (www.CUREepilepsy.org). Professor, Neuroscience and Neurosurgery Director, Yale Clinical Neuroscience Imaging Center Yale University School of Medicine

Transcript of Impaired Consciousness in Focal Seizures: Network Mechanisms and Treatment … · 2017-01-17 ·...

Page 1: Impaired Consciousness in Focal Seizures: Network Mechanisms and Treatment … · 2017-01-17 · Impaired Consciousness in Focal Seizures: Network Mechanisms and Treatment with Deep

Hal Blumenfeld, MD, PhD

Impaired Consciousness in Focal Seizures:  Network Mechanisms and

Treatment with Deep Brain Stimulation

Tuesday, January 31, 2017 9.00-10:00 am

The Chan Centre Auditorium, CFRI938 West 28th Avenue, Vancouver, BC

CURE(CitizensUnitedforResearchinEpilepsy)isa501(c)3dedicatedto<indingacureforepilepsy(www.CUREepilepsy.org).

Professor, Neuroscience and Neurosurgery Director, Yale Clinical Neuroscience

Imaging Center Yale University School of Medicine

Seizures & Epilepsy: Neurosurgical Opons · 2015. 4. 21. · Treatment of Seizures • Provoked Seizures – Treatment directed to the provoking factor • Unprovoked Seizures –

Seizures & Epilepsy: Neurosurgical Opons · 2015. 4. 21. · Treatment of Seizures • Provoked Seizures – Treatment directed to the provoking factor • Unprovoked Seizures –

RESEARCH PAPER NMDA receptor binding in focal epilepsiesjnnp.bmj.com/content/jnnp/86/10/1150.full.pdf · RESEARCH PAPER NMDA receptor binding in focal epilepsies ... evidence of seizures

RESEARCH PAPER NMDA receptor binding in focal epilepsiesjnnp.bmj.com/content/jnnp/86/10/1150.full.pdf · RESEARCH PAPER NMDA receptor binding in focal epilepsies ... evidence of seizures

Seizures Causes Classifications Treatments2 11 15 .ppt ... · infection Devel. ILAE 2010 Revised ... Focal Seizures (formerly partial seizures) • More common in adults than children

Seizures Causes Classifications Treatments2 11 15 .ppt ... · infection Devel. ILAE 2010 Revised ... Focal Seizures (formerly partial seizures) • More common in adults than children

Attribute Ranking for Lateralizing Focal Epileptogenicity ... · Temporal Lobe Epilepsy (TLE) • Epilepsy is a brain disorder involving repeated, spontaneous seizures of any type.

Attribute Ranking for Lateralizing Focal Epileptogenicity ... · Temporal Lobe Epilepsy (TLE) • Epilepsy is a brain disorder involving repeated, spontaneous seizures of any type.

Elaine Wirrell MD Mayo Clinic - Dravet Syndrome Foundation · Treatment of break-through seizures and status epilepticus ... Focal dyscognitive, atypical absences and obtundation

Elaine Wirrell MD Mayo Clinic - Dravet Syndrome Foundation · Treatment of break-through seizures and status epilepticus ... Focal dyscognitive, atypical absences and obtundation

Viktor's Notes – Brain Anomaliesneurosurgeryresident.net/Dev. Developmental anomalies/…  · Web viewWilms' tumor of kidney! Clinical Features. intractable focal . seizures. or

Viktor's Notes – Brain Anomaliesneurosurgeryresident.net/Dev. Developmental anomalies/…  · Web viewWilms' tumor of kidney! Clinical Features. intractable focal . seizures. or

OMIM Phase 2 Phase 3 Disorder Inheritance (Haloplex) (TSCA ......22 KCNT1 het c.862G>A; p.(Gly288Ser) Unknown M Developmental delay with seizures Yes 3m Focal seizures with secondary

OMIM Phase 2 Phase 3 Disorder Inheritance (Haloplex) (TSCA ......22 KCNT1 het c.862G>A; p.(Gly288Ser) Unknown M Developmental delay with seizures Yes 3m Focal seizures with secondary

Vinay Puri M.D. - USMF › wp-content › blogs.dir › 106 › files › ... · 2019-03-04 · seizures children •Complex partial ... •Idiopathic focal epilepsies of infancy

Vinay Puri M.D. - USMF › wp-content › blogs.dir › 106 › files › ... · 2019-03-04 · seizures children •Complex partial ... •Idiopathic focal epilepsies of infancy

September - October 2017 Focus on Epilepsy€¦ · Complex Partial Seizure Focal Impaired Awareness Seizure Psychomotor Seizure Focal Impaired Awareness Seizure Atonic / “Drop Attack”

September - October 2017 Focus on Epilepsy€¦ · Complex Partial Seizure Focal Impaired Awareness Seizure Psychomotor Seizure Focal Impaired Awareness Seizure Atonic / “Drop Attack”

Research Article Identification of Common Bacterial ...downloads.hindawi.com/journals/ijmicro/2016/4197187.pdf · Brudzinski sign, altered conscious level, seizures, and focal neurologicalsigns

Research Article Identification of Common Bacterial ...downloads.hindawi.com/journals/ijmicro/2016/4197187.pdf · Brudzinski sign, altered conscious level, seizures, and focal neurologicalsigns

Ictal semiology, functional anatomy and multimodal ... · Semiology For the differentiation of insular seizures with nonepi-leptic psychogenic seizures or other focal epilepsies the

Ictal semiology, functional anatomy and multimodal ... · Semiology For the differentiation of insular seizures with nonepi-leptic psychogenic seizures or other focal epilepsies the

1. Focal epileptic seizures emanate from an epileptogenic focus anywhere within cortical and sometimes subcortical brain regions, leading to localisable.

1. Focal epileptic seizures emanate from an epileptogenic focus anywhere within cortical and sometimes subcortical brain regions, leading to localisable.

Epilepsy and Seizuresseizure activity remains confined to local area bilaterally symmetrical and without local onset A. Simple partial seizures (consciousness not impaired) 1. with

Epilepsy and Seizuresseizure activity remains confined to local area bilaterally symmetrical and without local onset A. Simple partial seizures (consciousness not impaired) 1. with

MOVEMENT DISORDERS AND CNS INFECTION/INFLAMMATION...CNS Toxoplasmosis Presenting symptoms Fever Headache Altered mental status Focal neurologic complaints or seizures Supporting laboratory

MOVEMENT DISORDERS AND CNS INFECTION/INFLAMMATION...CNS Toxoplasmosis Presenting symptoms Fever Headache Altered mental status Focal neurologic complaints or seizures Supporting laboratory

Neuroimaging of Focal Cortical Dysplasiaseradiology.bidmc.harvard.edu/LearningLab/central/Bernson.pdf · Neuroimaging of Seizures: ... some form of cortical dysplasia (and 1.7% of

Neuroimaging of Focal Cortical Dysplasiaseradiology.bidmc.harvard.edu/LearningLab/central/Bernson.pdf · Neuroimaging of Seizures: ... some form of cortical dysplasia (and 1.7% of

THE RNS® SYSTEM A patient’s guide. - NeuroPace, Inc · The RNS® System A patient’s guide. 06 FOCAL SEIZURES Start in one part of the brain NORMAL EEG GENERALIZED ONSET SEIZURES

THE RNS® SYSTEM A patient’s guide. - NeuroPace, Inc · The RNS® System A patient’s guide. 06 FOCAL SEIZURES Start in one part of the brain NORMAL EEG GENERALIZED ONSET SEIZURES

CNNM2 Mutations Cause Impaired Brain Development · PDF fileCNNM2 Mutations Cause Impaired Brain Development and Seizures in Patients with Hypomagnesemia Francisco J. Arjona1., Jeroen

CNNM2 Mutations Cause Impaired Brain Development · PDF fileCNNM2 Mutations Cause Impaired Brain Development and Seizures in Patients with Hypomagnesemia Francisco J. Arjona1., Jeroen

Seizures - Febrile Seizures

Seizures - Febrile Seizures

Ablation of D1 dopamine receptor-expressing cells generates ...Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired

Ablation of D1 dopamine receptor-expressing cells generates ...Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired

Safety in the Epilepsy Monitoring Unit hematoma, and fractures without falls ... nursing care to ensure safety . Seizure Classification • Focal seizures –With and without impaired

Safety in the Epilepsy Monitoring Unit hematoma, and fractures without falls ... nursing care to ensure safety . Seizure Classification • Focal seizures –With and without impaired