Immune System Day 4

"Treasure the love you receive above all. It will survive long after your good health has vanished." -Og Mandino

Today’s Agenda

Finish Non-specific immunity notesQuizSpecific immunity notes—obj. 9, 10

Bacterial leprosy infection just under skin.

“border line leprosy—numb centers

2. Phagocytic cells--macrophages

i. Phagocytes include macrophages and neutrophils

ii. Phagocytes engulf and destroy pathogensiii. Phagocytosis is enhanced when pathogens

surface is altered by antibodies or complement proteins

iv. Cell killing is enhanced by respiratory burst

Obj. 6

3. Natural killer cells – attack and lyse body cells infected by viruses or that are cancerous.

Obj. 7 Inflammatory response1. Skin & mucous membranes2. Phagocytic cells3. Natural killer cells

4. Inflammatory response– damaged tissues release histamines–Histamines make vessels leaky, releasing

phagocytes & clotting factors–Phagocytes engulf bacteria–Platelets form clots

Obj. 7

Obj. 5 Nonspecific Defenses: things your body uses to defend against ANYTHING

5. Antimicrobial substances–Interferon–Complement proteins

Obj. 8 Fever1. Skin & mucous membranes2. Phagocytic cells3. Natural killer cells4. Inflammatory response5. Antimicrobial substances

6. Fever–Macrophages release pyrogens–Hypothalamus elevates temperature–Liver & spleen supply less iron–Bacteria don’t grow well without iron–Metabolism increases speeding repair.

105

98.6

Ready for a Quiz???

Objective 9

B & T cells come from bone marrow.B’s mature in bursa (bone)T’s mature in thymus

Objective 10

Antigens are substances capable of causing an immune response.

variable region