IL LASER A FIRENZEstatic.sif.it/SIF/resources/public/files/congr10/mc/masotti.pdf · aesthetical...

IL LASER A FIRENZE

Leonardo Masotti

Congresso Società Italiana di FisicaBologna 24 Settembre 2010

Premesse sul Laser a Firenze1941 Già scoperto il principio di interferenza inversa di G.

Toraldo1955-1958 Collaborazione di G. Toraldo con l’Istituto Nazionale di

Ottica e con il Centro Microonde del CNR.Tra i tanti risultati importanti, citiamo:-la previsione e dimostrazione sperimentale dell'esistenza delle onde evanescenti; e specialmente-lo studio del campo elettromagnetico di un elettrone relativistico, rappresentato in termini di onde evanescenti, di particolare valore per la raffinata analisi fisico-matematica e per le interessanti applicazioni alla classe degli effetti quasi-Cerenkhov;-il settore delle lenti geodetiche, ideate per le microonde e trasportate poi nel campo dell'ottica integrata;-gli studi sulle antenne.

1958 Libro La diffrazione della luce, Einaudi 1958 G. Toraldo di Francia professore di Ottica all’UNIFI

Cronologia del LASER a Firenze 1958 Articolo di Shawlow & Townes sul Physical Review1960 Primo Laser a rubino di T. Maiman1961 Primo Laser Elio-Neon di A. Javan1962 Primo Laser a semiconduttore di R. Hall1962 Missione in USA della Commissione CNR “Laser e

Maser” (con Arecchi, Sona e Gatti da Milano; Fagioli, Pratesi e Toraldo da Firenze; Bertolotti e Sette da Roma)

1963 Inizio ricerche al Centro Microonde su Laser1964 Primo Laser a CO2 di K. Patel1966 Sviluppo di Laser a Elio-Neon al Centro Microonde1967 Sviluppo di Laser a Rubino al Centro Microonde1970 Istituzione del Laboratorio di Elettronica Quantistica

del CNR1974 Studio fattibilità Progetto Finalizzato CNR Laser di

potenza

Alcuni risultati tecnologici al C.o Microonde e poi al Lab. Elettr. Quantistica di R. Pratesi, P. Burlamacchi, R. Salimbeni, P.

Mazzinghi

Prototipo di Laser a Rubino (1968)

Prototipo di Laser a CO2 TEA (1975)

Prototipo di Laser a Coloranti (1974)

Prototipo di Laser a Eccimeri (1978)

Group History and Development of the Business

1981 El.En., acronym of Electronic Engineering, is established inFlorence (Italy). It has as its object the design, manufacturingand sale of electronic and mechanical equipment for industrialand research applications.

El.En. enters into its first cooperation agreements with ItalianResearch Institutes (University of Florence, CNR and ENEA),for the development of switching high voltage power supplies tobe used in experimental set-ups.

Development of the first CO2 laser sources, as well as ofswitching mode power supplies for lasers.

El.En. designs and manufactures the first kits for therapeuticlasers.

Kits are sold to manufacturers of biomedical systems forphysiotherapy applications.

1982

1983

1984


1986 1989

El.En. develops and manufactures complete laser systems andmanufactures the first CO2 dental lasers, as well as CO2 laserequipment for gynaecology. Moreover it designs an excimerlaser for angioplasty, and develops its first laser cuttingprototype system.

Establishment of DEKA M.E.L.A., for the distribution of medicalequipment manufactured by El.En., in the domestic andinternational market.

Establishment of Lasit S.r.l, for design and production of CO2

laser marking systems for industrial applications.

Establishment of Cutlite Penta S.r.l., manufacturer of industriallaser cutting and marking systems powered by El.En.’s laserssources.

1990

1992

Group History and Development of the Business1993 Acquisition of Laser Valfivre Sorgenti e Sistemi’s assets,

the Valfivre brand of the European pioneer in lasermanufacturing.

El.En. purchases a 50% stake in Quanta System S.r.l, acompany which designs and manufactures laser systems forscientific applications.

Establishment in France of DEKA S.a.r.l., distributor of DEKAmedical and aesthetical lasers on the strategic Frenchmarket.

The company’s subsidiary Cutlite Penta acquires control ofOT-LAS S.r.l. and Neuma Laser S.r.l., strengthening itsposition in the CO2 laser marking systems market.

IPO on the “Nuovo Mercato” of the Italian Stock Exchange

1996

2000


2001 Establishment in Germany of DEKA – LMS GmbH, distributorof medical and aesthetical lasers.LMS is the former DEKAdistributor of medical and aesthetical lasers in Germany.

El.En. purchases a 60% stake in Cynosure Inc., an U.S.company which develops and manufactures laser systems fordermatological and aesthetical applications.

Cynosure also distributes selected DEKA medical andaesthetical products in the U.S. market, under its own brandname.

Establishment of DEKA – DLS GmbH, for the distribution ofDEKA dental lasers in Germany.

Acquisition of Asclepion Laser Technologies GmbH, aGerman company renowned for development and productionof surgical, dental and dermatological laser systems.

2002

2003

Group History and Development of the Business2003 El.En. purchases a 70% stake in Lasercut Inc., an U.S.

company which develops and manufactures industrial cuttingand marking systems.

Establishment of DEKA Laser Technologies LLC, for thedistribution of DEKA dental lasers in U.S.A..

DEKA M.E.L.A. purchases a 60% stake in Asa S.r.l, an Italiancompany which develops and manufactures medical devicesfor Lasertherapy and Magnetotherapy.

El.En. acquires control (60%) of Quanta System S.p.A. and an additional 20% of Cynosure Inc.

IPO of Cynosure Inc. on the “NASDAQ” of the NY Stock Exchange

Set up PENTA-CHUTIAN Co. Ltd Chinese joint venture and CUTLITE DO BRASIL Ltda

2004

2005

2007

El.En. Group TodayIndustrial High-Tech Group operating in Optoelectronics with proprietarytechnology

Know-how developed through more than 29 years’ experience

More than 30 companies operating worldwide

International Distributors Network

Competitive R&D on the global market

Consolidated revenues of 222M€ in 2008 (15% more than 2007, about30% less than 2009 but the 2010 shows a growth, in Q1 and Q2, of 27%over the 2009Q1 and Q2 )

Over 900 direct employees worldwide

Active after sale Service network

Attività di El.En. Group

Laser medical applicationsMAIN APPLICATIONS

Dentistry: little amount of anaesthetic, no drill noise and vibration foradvanced therapeutic solutions to maximize clinical advantage withoptimal post-operative prognoses and results

Surgery and plastic surgery: laser is a sterilized bistoury, lasersears so the healing is rapid with an aesthetic perfect result, thedevelopment of laser technology and the ever-increasingunderstanding of laser-tissue interaction has led to widespread useof lasers in the operating room

Sport medicine: in functional re-education and sports relatedindications optimizing performance and recovery time of muscularfunctions, salutary biostimulation without secondary effects

Laser medical applicationsMAIN APPLICATIONS

Aesthetic medicine and surgery: selective interaction for hairremoval with, controlled laser energy delivery: body care, skinrejuvenation, tattoo removal, angioma removal

Gynaecology: no-contact operations in laparoscopic andcolposcopic surgery ensuring rapid post-operative recovery

Endoscopic surgery: laser energy, transported through very thinand flexible optical fibers, allows for inducing controlled and localizedhyperthermia in less accessible areas

ENT surgery: for the micro-surgical endoscopic treatment of severallaringeal and ear pathologies (myringotomia-otosclerosis)

Laser medical applicationsResearch & Development

Applications

- Dermatology- Aesthetic surgery- Physiotherapy- Otolaryngology- Dentistry- Veterinary medicine- Gynaecology

2

Sources

CO2

Nd:YAG

Er:YAG

- Dentistry- Physiotherapy - Aesthetic medicine- Dermatology- Endoscopic surgery

- Dermatology- Dentistry

Sources Applications

Ho:YAG

Organic Dye

Excimer

Coppervapour

- Orthopaedic surgery- Urology

- Dermatology

- Dermatology- Angioplasty

- Dermatology

Laser medical systems

Laser medical applications

NEW APPLICATION

Minimally invasive diagnosis: little invasive diagnosis, no trauma,it is possible to have diagnosis and therapy in one session

Minimally invasive therapy: little invasive surgery, little amount ofanaesthetic, no trauma, maximize clinical advantage with optimalpost-operative prognoses, ensuring rapid post-operative recovery

Laser veterinary applications

Laser industrial systems

Laser in restoration

Restoration with El.En Lasers Welding SystemFIRENZE,Monstrance from Plaermo, Baroque period

Laser in restoration

CARATTERIZZAZIONE DI SUPPORTI CARTACEI

Libreria degli Uffizi: stanza dei documenti antichi

02

46

8 02

46

0

0.5

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SCORE 2SCORE 1

Contemporary paperAncient paper

Cardboard

Handmade paper

Dictionary

Restorationpaper #1

Restorationpaper #2

Tissuepaper

Writing paper

Contemporary paperAncient paper

PROVE IN CAMPO AL COLOSSEO

Ultrasonic transducers based on fiber optics

• High frequency and wide band • MiniaturizationMicroscopic tissue characterization Minimal invasive intervention

Ultrasonic transmitter

Ultrasonic receiver

Endoscope

Syringe needle

Impiego dei due trasduttori:

immagine in riflessione

Generazione opto-acustica ericezione acusto-ottica

Ultrasound detectionsample C-Mode images

approx. wire diameter: 0.2 mm

the healing process was found to develop in a shorter time and with less inflammatory and foreign-body reactions

the architecture of the cornea regained an almost physiological aspect with continuity of epithelium and endothelium and regularly organized collagen fibers in the stroma .

CONTROL day 15 CONTROL day 7 LASER day 7

H&E H&E

Animal studies on the healing process

Results of histology exams in a follow up study up to 90 days : IFAC-CNR



LASER day 15 CONTROL day 15

H&E H&E






H&E H&E



Results of histology exams in a follow up study up to 90 days :




H&E immunohist

Animal studies on the healing processIFAC-CNR

Thanks for your attentionwww.elengroup.com

Le mappe tematiche mettono in evidenza la differenza del blocco I rispetto agli altri tre.

L’area del blocco I e II è un ripristino dopo un terremoto e furono impiegati pezzi originali e non.

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CARATTERIZZAZIONE DEI BLOCCHI

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La prima mappa tematica mette in evidenza la presenza di Chl e uno specifico pixel corrisponde alla fluorescenza relativa a una pianta superiore. Infatti un anno dopo si è verificato che adesso questa pianta era visibile. Le altre mappe quantificano la fluorescenza dovuta all’ Chl per gli altri due cluster.

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One year later …

IDENTIFICAZIONE DEGLI AGENTI BIODETERIOGENI

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Segnale RFB-Mode

32 34 36 38 40 42 44 46Tempo [µs]

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MEZZI DI CONTRASTO ECOGRAFICI2002

Impiego dei contributi di Intermodulazione per Imaging Ecografico

Frequency [MHz]0 10 15 20

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Metodo per separare i contributi di Intermodulazione

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Segnale con componente a banda stretta

Componenti di intermodulazione a

Elevata Risoluzione

2005

Il Gruppo El.En. oggi Industrial High-Tech Group operating in Opto-electronics with

proprietary technology

Know-how developed through 29 years’ experience

More than 30 companies operating worldwide applicative andcomplementary market and application segments.

Consolidated Revenues of 222 M€ in 2008 (15% more than 2007, about30% less than 2009 but the 2010 shows a growth of 27% over the 2009!)

International Distributors Network

Competitive R&D on the global market

Over 900 direct employees worldwide

Active after sale Service network

IL LASER A FIRENZEstatic.sif.it/SIF/resources/public/files/congr10/mc/masotti.pdf · aesthetical...

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