IBM Research Intro-Syngenta

8/19/2019 IBM Research Intro-Syngenta

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IBM Research:Increasing the Speed & Scale of Impact

October 21, 2015

Larry L. Light

Business Development Executive

IBM Research

© 2014 International Business Machines Corporation


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© 2014 International Business Machines Corporation 2

Engagingin newways

Datatransforming

industries

Cloudtransforming

IT

Science & Technology

Industries &Engagement

Research

CloudResearch

CognitiveResearch

IBM Research: Aligned to Lead


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Cloud Systems GTS GBS

Watsonand

WatsonHealth

CommerceSecurity Analytics

Research is the foundation of IBM’s future growth

Intellectual Property

Research


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IBM Research: Unmatched Talent

© 2014 International Business Machines Corporation

Brazil

T.J Watson

Almaden

Austin Ireland

Zurich Africa

IndiaHaifa China

Australia

3,000 Researchers$6.2B R&D in 2013

Japan


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A Culture of Innovation and Leadership

10 US National Medals ofTechnology

5 NationalMedals of Science 6 Turing Awards

11 Inductees in NationalInventors Hall of Fame

5 Nobel LaureatesScanning Tunneling Microscope

Electron TunnelingEffect

High TemperatureSuperconductivity

Nuclear MagneticResonanceTechniques

Basis forMRI today

Copper ChipTechnology

DRAM

Excimer Laser

High Performance Computing

Millennium Prize

Magnetic Disk DriveStorage

2013 Medal of Honor withPurple Ribbon

Chieko Asakawa


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© 2014 International Business Machines Corporation 6 6

External Recognition (Honors and Awards)

Ensures technical vitality

Attracts, retains and energizesworld-class scientists

Generates luster for IBM and IBMResearch

Measurement of our Technical

contributions


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Leading in key research disciplines

ComputerScience

MathematicalScience Physics

MaterialsScience

BehavioralScience

ChemistryElectrical

Engineering

ServiceScience

BusinessInnovation

Technology

Innovation

SocialInnovation

DemandInnovation

Science &Engineering

Business &Management

Social &CognitiveSciences

Economics& Markets


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21st year of patent leadership

Source: IFI CLAIMS Patent Services

6809

IBM

N u m b e r o f P a t e n t s

1455

0

2660

Microsoft Intel

1775

Apple

1360

HP

540

Amazon

525

Oracle

442

Symantec

374

EMC

156

Accenture

7000

>5x >40x>10x

X22nd


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Explosion of Data across all Industries

Source: IDC’s sixth annual study of the digital universe (2012)

Mobile Social

Cloud

Internet ofThings

0

5

10

15

20

25

30

35

2009 2010 2011 2012 2013 2014 2015 2016 2017

E x a b y t e s

Multimedia

Manufacturing &Enterprise IoT

Consumeroriented IoT

Text data

Genomic

Structured

Other


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IBM has launched the Next Era of Computing

TabulatingSystems Era

Cognitive SystemsEra

ProgrammableSystems Era


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Journey to Watson: a deep foundation in computer science

MachineLearning

NaturalLanguage

Processing

HighPerformanceComputing

KnowledgeRepresentationand

Reasoning

QuestionAnsweringTechnology

UnstructuredInformation

Management


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Software

DefinedEnvironment

Atomic andNano-scale

Data-centricSystems

Visual Analyticsand Interaction

Context andLearning

Cognitive

Computing

Key technologies for the next era of computing

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Improving cacao, avocado qualityDiscovering markers for selection, utilizing genetic and

phenotypic variation in mapping populations

Improving robustness of bio-energy grassesDiscovering genes for drought, flood, salt stress resistance

Collaborators/Clients in Ag Genomics

Improving quality of cultivated plantsGenerating smarter breeding decisions, guided byaccurate genomic selection methods and simulations


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Computational Biology Research at IBMthe intersection of Information Technology and Life Sciences

Managing and Analyzing the Data Explosion

Dealing with Complexity

Predicting Biological Outcomes with Large Scale Computing

Genomics

Systems: Workflow acceleration, appliance, …

Software: Data integration for translational research

Analytics: Watson, IRiS, iXORA, EUResist, CliG, …

… pharma, diagnostics

… academic medical

… agriculture, food

… food, pharma

for LS

… pharma

… medical devices

… food+

Deep Computing

Bioinformatics, Neuroinformatics

Bio-nanotechnology… diagnostics, medical devicesMRL, Nanotechnology + Nanochannels, Biosensing, …


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©2015 IBM Corporation 23 October 2015 IBM Research17

An IBM Research-client Partnership to Drive Transformation

• Analyze data for optimum production

• Learn from similar plants, processes

• Improve operational efficiency

• Monitor and assure compliance

• Map client requirements to available andknown solutions

• Optimize price performance availability

• Find adjacent solutions and use cases

• Design material for desired properties

• Leverage Known Solutions

• Access all relevant IP and knowledge

• Improve for Critical Factors

AcceleratedResearch & Development

Optimized ManufacturingProduction and Costs

Optimal solution forclient or market

Cognitive Computing for Materials Industry

HPC Industry Cloud

Faster time to solution Lower cost to manufacture Maximize value to client


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©2015 IBM Corporation 23 October 2015 IBM Research18

Foundational Technology for Strategic Partnerships

Cognitive Systems


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Nanomedicine: Bold Agenda, three major thrust enabled by macromoleculartherapeutics and therapeutic carriers

Nano-

medicine

Cancer research Infectious Disease Aging related diseasesLeverage polymer chemistry expertise

to encapsulate, deliver and releasetherapeutics: efficacious delivery andsynergistic delivery to mitigate tumor

and tumor stem cells to prevent metastasis.Broad impact across many institutes and

hospitals in Cambridge

Drug resistant bacteria and biofilms are

two of the grand challenges of this decade.Central to this challenge is the developmentof macromolecular therapeutics that preclude

resistance. Moreover, since the advent of virusessuch as Ebola, Marburg, Chikungunya, IBM has

developed novel strategies to prevent suchInfections and mitigate resistance development.

Aging associated diseases are pervasive and

include cardiovascular disease, arthritis,cataracts, type 2 diabetes and brain relatedsuch as Alzheimer’s and Parkinson’s diseases.

IBM will leverage technologies developedfrom thrust 1 and 2 to enable drug delivery

across the blood-brain-barrier and to treat heartdisease, arthritis, hip and knee replacements.

36 nm

IBM will bring expertise in polymer chemistry and bioinformatics to address critical issuesassociated with encapsulation, transport, targeting and delivery of biologics, drugs and genes toaddress the demanding needs of the industry

Loaded nanoparticlesnavigate the blood-brain-

Barrier (Alzheimer’s etc)


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Key antimicrobial challenges for agricultureCitrus greening- Candidatus Liberibacter

Huanglongbing “yellow dragon disease”Largely seen in Asia until 2004 – first reportin Western hemisphere in Brazil

Symptoms• Yellow shoots• Twig dieback• Mottling and chlorosis• Reduced fruit size and quality• Bitter fruit, low juice yield

Transmission of Candidatus liberibactera • Citrus psyllid during phloem feeding• Plant grafts

Current treatment:• Eradication and replacement

• Thermotherapy of graftwood• Chemotherapy with tetracycline or penicillin• Vector control with dimethoate, carbofuran,

methomyl, or malathion sprays


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CoupledModels

Circulation

Runoff

Weather

Food Web

Sensor

Data

Sensor

DataPhysical

• Current/flow• Temperature• Pressure• Turbidity

Chemical• Dissolved O2• Sal inity• Nitrates

• Phosphates• Chlorophyll

Biological• Algae• Cyanobacteria• Diatoms• Phytoplankton• Zooplankton

• Rising NaCl concentration

• Proliferation of invasive species

Survey Data• Bathymetry (depth)• Topography (watershed)


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© 2015 IBM Corporation

ESTABLISHING A IBM-SYNGENTA JOINT RESEARCH FRAMEWORK

Life Sciences Crop Health Digital Farming Insights

• Genomics

• Biology/Modelling

• Food Safety

• Chemistry/Materials

• Nanoscience

• Accelerated

Discovery

• Mapping

• Weather

• Yield Prediction

• Precision Irrigation

• Social Analytics

• Marketing Insights

• Security

• Competitive• Regulatory

IBM Research Intro-Syngenta

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