ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ]...
Transcript of ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ]...
![Page 1: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/1.jpg)
![Page 2: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/2.jpg)
ESMO
30
1/ 5
[ ESMO/ Ant i cancer Fund Gui des f or Pat i ent s ]
Rol f A. St ahel
ESMO
ESMO ESMO Gui des f or Pat i ent s ESMO
ESMO ESMO/ Ant i cancer Fund Gui des f or Pat i ent s
![Page 3: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/3.jpg)
ESMO
(Ant i cancer Fund
( Eur opean Soci et y f or Medi cal Oncol ogy: ESMO) ESMO
ESMOESMO
ESMO
( Ant i cancer Fund)
( ESMO)
![Page 4: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/4.jpg)
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
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Dr . Annemi e Mi chi el s ( Ant i cancer Fund) Dr. Gaut hi er Bouche ( Ant i cancer Fund) Dr. Svet l ana Jezdi c( ESMO) Dr. Al i ci a Oki nes ( ESMO) Prof . Davi d Cunni ngham ( ESMO) Dr. Wi l l i am Al l um ( ESMO) Pr . Lorenz Jos t ( ESMO )
![Page 5: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/5.jpg)
Nat i onal Cancer I ns t i t ut e ( NCI )
*
90%
* * * * *
* * *
胃
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−
− GIST
−
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52 60 80
2008 150, 000
100 1 2 100 0. 5 1
100 4 100 2
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**
**
*
• Hel i cobact er pyl or i (: H. )
*
1%• 50%
*
• : o
*
* *
A C
o 2
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o
o
• :
o E- cadher i n *
** *
BRCA1 BRCA2 *
o
• : o MALT
MALT
o o
o
o B12
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Eps t ei n-Bar r **
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: − − − − − − −
50
1
*
**
1
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*
*
CTCT *
X PET *
* **
*
* * *
*
**
*
*
*
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• • • • * • CT
•
* TNM
( T) *( N) *(M)
*2 *
3
St age 0 *
St age I * *
* * St age I St age I A I B
St age I A * **
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St age I B − * * 1- 6*
− * *
St age I I St age I I *
− * *7- 15 *
− * 1- 6 *
− * * St age I I I * * 15 *
**
St age I I I I St age I I I A I I I B St age I I I A − * 7- 15 *
− * 1- 6 *
− *
St age I I I B * 7- 15 * St age I V 15 *
: * 15 *
*
• *
* ** 2 *
* *:
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o *
o *
** *
* *FI SH* *
o HER2
HER2* HER2
HER2 *
HER2HER2 HER2
HER2
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* *
*TNM
St age 0 I I I )
EMR * 2cm
ESDESD
*
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*
• I b I I I
1/ 3
•
*
15 *
* *
•
* *
• *
*
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*
3 ( * E * C 5- * F )
ECFE C *( X) ECX ECF
•
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1.
5- * * 2 5
*
2. *
St age I I I IV
**
* s t age I V
* St age IV
15 *
* :
•
•
• *
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St age I V :
• * •
*
*
*
• * 5- FU* *
• ** ECF
*: E *: C 5- FU*: FECF 5- FU* ( F) *( X) *( C)
*( O)ECX EOX 5- FU
* 6
•
*
• * 5- FU* * * 5- FU*
*
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* **
*
* **
*
* 3*
**
HER2 * HER2* FI SH*
* HER2* * *
*
s t age I V
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* : • • * * • * • 5- FU * * • • *
*
•
• • *
• 5- FU* *
**
• *
• *
• *
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• *
4 1 2 *
• *
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•
• *
•
6 1
*B12
B12
:
• • • *
*
:
• • • •
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*
* **
*
**
*
* St age I V
* *
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FISH/ i n s i t u FI SH
5- FU
DNA 5- FU
5- FU
DNA
Eps t ei n- Barr EBV
EBVEBV
![Page 27: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/27.jpg)
DNA
/
5- FU
5- FU DNA RNA 5- FU I n t he body, 5- FU
DNA
( )
DNA
DNA
![Page 28: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/28.jpg)
12 3
EGFR79 89%
90% EGFR
23
46
![Page 29: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/29.jpg)
DNA
HER2
HER2HER2
1/ 4 1/ 5 HER2
![Page 30: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/30.jpg)
EGFREGFR
KRASEGFR EGFR
( VEGF)VEGF
X CT MRI
( 1) ( 2)
( 3)
50
![Page 31: ÏÁø Ì) ¢«ÝÛ¸ÂÖ( 8 - ESMO · Davi d Cunni ngham (ESMO) Dr . ... o W ÒÔ¼ ] Ç×õíIL;ÊÌxüMALT ýIL;Ô ½,p Ò¾ I61 û (" * ' MALT IL;Ô nw @I3:17M=KI ¥ &) # +*"](https://reader035.fdocuments.us/reader035/viewer/2022062601/5c65271009d3f2b26e8c439c/html5/thumbnails/31.jpg)
I HC
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