IAN Test Drive
description
Transcript of IAN Test Drive
![Page 1: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/1.jpg)
IAN Test Drive
![Page 2: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/2.jpg)
![Page 3: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/3.jpg)
![Page 4: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/4.jpg)
![Page 5: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/5.jpg)
Baylor• Principal Investigator: Dr. Robin Goin-Kochel• Study Title: Autism Treatment Network• Location: Baylor College of Medicine/Texas Children's Hospital• Inclusion: 1. Children between the ages of 3.0 –17.9; the subject will be
expected to complete the protocol by his/her eighteenth birthday. 2. Parent/Caregiver fluent in written and spoken English/ English spoken in the home with the child at least 75% of the time (because most assessment questionnaires are validated in English only). (Additional inclusion criteria, such as having an ADI-R/ADOS confirmed ASD diagnosis, will be done at the ATN site.)
• Exclusion: 1. Blindness precluding valid testing. 2. Deafness precluding valid testing. 3. Ongoing or planned participation in another research protocol that would either prevent successful completion of planned study testing or invalidate the results of study testing.
![Page 6: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/6.jpg)
Baylor
![Page 7: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/7.jpg)
Baylor
300 Subjects
![Page 8: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/8.jpg)
Baylor
![Page 9: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/9.jpg)
![Page 10: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/10.jpg)
University of Iowa• Principal Investigator: Dr. Karla McGregor• Study Title: The Development of Word Meaning• Location: University of Iowa • Catchment area: Iowa or 100 miles of Iowa City• Inclusion: chronological age = 8 to 13 years; verbal; high-
functioning (not mentally retarded); normal hearing acuity• Exclusion: none• Sample size: 30
![Page 11: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/11.jpg)
Iowa
![Page 12: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/12.jpg)
Iowa
![Page 13: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/13.jpg)
![Page 14: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/14.jpg)
Multi-Center Baby Sibs Study• Principal Investigator: Dr. Joe Piven et al• Study Title: Brain Development in Infants at High Risk for Autism• Location: (Multi-center) University of North Carolina at Chapel Hill,
Washington University, University of Washington, Yale University• Inclusion: under 12 months of age; at least one older sibling with a
documented diagnosis of autism• Exclusion:• * Certain medical and genetic conditions • * MRI contraindication• * Non-English speaking
![Page 15: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/15.jpg)
Baby Sibs (ACE Study, Joe Piven et al)0
1020
3040
Freq
uenc
y
0 2 4 6 8 10age_in_months
N=160
![Page 16: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/16.jpg)
![Page 17: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/17.jpg)
![Page 18: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/18.jpg)
![Page 19: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/19.jpg)
Exploring the Treatment Data
![Page 20: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/20.jpg)
Treatments0
100
200
300
400
Num
ber o
f chi
ldre
n
0 5 10 15 20 25 30 35 40Number of Treatments
updated 18 Jun 2007
Number of Treatments per Child
![Page 21: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/21.jpg)
Top Twelve Treatments Nationwide1. Speech and Language Therapy2. Occupational Therapy 3. Applied behavior analysis (ABA)4. Social Skills Group 5. Picture Exchange Communication System (PECS)6. Physical Therapy7. Visual Schedules8. Sensory Integration Therapy9. Social Stories10.Risperdal11.Casein-free diet12.Melatonin
![Page 22: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/22.jpg)
Intervention Improvement Expected Improvement
ExpectedRisk
ExpectedBurden
N
Keppra 2.8 3.7 2.6 2.1 15
Ritalin 2.7 3.4 2.6 2.1 32
Feingold diet 2.7 2.8 1.1 3.4 15
Homeopathy 2.5 2.5 1.6 2.4 23
Melatonin 2.5 2.9 1.7 1.5 179
Clonidine 2.5 3.2 2.2 1.9 135
DTT 2.4 3.5 1.4 2.6 115
Prayer 2.4 2.9 1.1 1.2 133
Remeron 2.4 3.3 2.5 1.9 11
![Page 23: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/23.jpg)
Parental Age
![Page 24: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/24.jpg)
Parental Age0
200
400
600
800
Freq
uenc
y
20 25 30 35 40 45 50 55 60 65FathersAge
![Page 25: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/25.jpg)
Moternal Age0
200
400
600
800
1000
Freq
uenc
y
20 25 30 35 40 45 50 55 60 65MothersAge
![Page 26: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/26.jpg)
020
040
060
0
20 25 30 35 40 45 50 55 60 65 20 25 30 35 40 45 50 55 60 65
1 2
Freq
uenc
y
FathersAgeGraphs by gender_id
32.8
33.0
P=0.5
MaleFemale
![Page 27: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/27.jpg)
![Page 28: IAN Test Drive](https://reader035.fdocuments.us/reader035/viewer/2022062315/5681608f550346895dcfb3fd/html5/thumbnails/28.jpg)
Action Points• Recruit• Analyze• Write• Suggest/Author New Content