Hypothesis Estrogen and Progestrone are proctective factors against high systolic blood pressure...
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Transcript of Hypothesis Estrogen and Progestrone are proctective factors against high systolic blood pressure...
Hypothesis
• Estrogen and Progestrone are proctective factors against high systolic blood pressure which is a risk factor for the development of cardiovacular diseaes
How will participants be selected
• Outpatient settings i.e. doctor offices, specialty clinics
• Community centers• Public Health clinics
Why important to study/what we don’t know
• There has not been much research on estrogen and a correlation to systolic blood pressure
What we know
• Women who are postmenopausal have an increase in systolic blood to that of men near age 60-69
• Women rate of CVD increase post menopause• Boys on average have a higher systolic than
boys• Systolic stays with the person into adulthood
What pops are most affected
Study Design
• Cohort over 5 years• Population: – 500 Women and Men aged 45-65. 250 men 250
women. – 175 middle class women/men ;175 women/men
below poverty line– Non smokers for at least 8 years– Ethnicity AA Caucasion Asian-American
What comparisons will be made
• Compare levels of estrogen/progersteron via intravenous blood test
• Compare those levels of hormones to systolic blood pressure
• If a person develops CAD their out of the study DATA COLLECTED EVERY THREE MONTHS
Measures used to test hypothesis