Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson...
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Transcript of Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson...
Human embryonic stem cells
Human induced pluripotent stem cells
Yamanaka S. et al. Cell 2007Thomson J. et al. Science 2007
Proteomic comparison
14 days of analysis15,091 phosphorylation sites7,962 unique proteins
Multiplexed enrichment analysis
Chromatin Modifying Proteins
Note reversed scale
Protein-protein interactions
Protein-protein interactions
Becker, KA. et al Journal of Cellular Physiology 2007
Reprogramming networks
Cyclin-dependent kinase 2
mRNA up , protein down
Kinase Analysis