Homeostasis within the Circulatory & respiratory Systems
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Transcript of Homeostasis within the Circulatory & respiratory Systems
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Homeostasis within the Circulatory & respiratory Systems
AP Biology:Big Idea #2 & #4Chapter 42
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Learning Goals Identify how oxygen and carbon dioxide are
transported and their effects on breathing rate.
Identify a dissociation curve and explain the role of partial pressure of oxygen and oxygen saturation in delivery of oxygen to the body.
Identify and explain how heart rate is controlled.
Identify changes in heart rate and connect to the function of the heart.
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Moving GassesDiffusion moves
substances from areas of HIGH to LOW pressure
Gasses dissolve in and out of solution based on partial pressure
Partial Pressure of O221% O2 X 760mmHG =
160mmHG
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Partial Pressure Gradients drive the transport of gasses
Partial pressure of gasses varies throughout the circulatory system
Where is ppO2 high? Low?
Where is ppCO2 high? Low?
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Role Of Pressure
CO2: Greater at tissues; movement directed AWAY from tissues.
Oxygen: Greatest in alveoli; movement directed toward tissues
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Role of Transport PigmentsO2 solubility is low,
therefore plasma alone cannot carry enough
Hemoglobin can carry 4 oxygen atoms each
Note: Hemoglobin saturation (or carrying oxygen) does not change ppO2
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Other functions of RBC Fig 42.32Transport of
CO2 Undergoes a
reaction and becomes carbonic acid.
Equilibrium shift @ lungs back to CO2.
Hemeoglobin acts as a buffer
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MeasurespO2: partial pressure of oxygen at a
given atmospheric pressure.Saturation of O2: amount of oxygen
bound to hemoglobin
Concentration of O2: dependent on saturation and pressure.
Normal: >95% saturation 100 mm/mg pO2 20 ml/100mL blood
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Oxygen Dissociation Curve
• Shows cooperative binding effect, more oxygen = easier binding
• High pressure = high saturation, O2 bound to hemoglobin (Where ?)
• Low pressure = low saturation, O2 released from hemoglobin (Where?)
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What happens when the muscles need more oxygen?
Bohr Shift:
Saturation decreased at lower pH.
More O2 falls off blood and enters body tissues.
What do you think the decrease in pH does to hemoglobin to cause this phenomenon?
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The Bohr shiftFactors that affect
binding:pH (exercise)temperature
Other binding proteinsMyoglobinFetal Hemoglobin
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The High Altitude Problem The concentration of oxygen in air is 20.9%.
Pressure at sea level is 760 mmHg.
1) What is the pO2 at sea level?
2) What changes at high altitude?
3) How does that affect physiology?
4) What changes does the body undergo when it spends weeks at high altitude?
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Chemoreceptors detect CO2 levels as first indicator
High CO2 levels normally signal low O2 levels
Underwhat conditions is can receptors be “tricked”?
Backup system: O2 receptors in the heart
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How does blood gas affect breathing rate?
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Respiratory System Case StudyWhat happens when a person is
afflicted with carbon monoxide poisoning!!!
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Discuss answersThis is a practice with multiple
choice!!!
What do you need to know to answer the question?!?
Why are wrong answers wrong and why is the right answer right?!?!
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Control of Circulatory SystemBlood pressure
Heart Rate
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Blood Pressure
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What do the values tell us?
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Review: Arteries and VeinsArtery: Away Vein:
Towards
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Review: Heart/Lung Circulation
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Structure meets functionReview: What is an intercalated disk? What is a gap junction?
What signals muscles to contact? Cardiac muscles?
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Nervous Control
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Heart Rate and Pacemaker
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EKG with Letters
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Abnormal heart RhythmsDescribe and Draw each of the abnormal heart
rhythms:
Atrial FibrillationTachycardiaBradycardiaVentrilcular Fibrillation
Then, write a case study for a patient and have a partner determine which rhythm he/she would likely experience.