Home Mechanical Ventilation Ventilation.pdf · Spinal cord injury ≥ C4, Bilateral diaphragm...
Transcript of Home Mechanical Ventilation Ventilation.pdf · Spinal cord injury ≥ C4, Bilateral diaphragm...
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Home Mechanical VentilationAnthony Bateman
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What is Long Term Ventilation?
LTV is the provision of respiratory support to
individuals with non-acute respiratory failure
Progression of expected disease – Genetic
disorders, inherited and acquired neuromuscular
disorders
Failure of weaning from acute respiratory
support
It does not require the sophistication of ICU
setting
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Conditions known to benefit or could
benefit from LTMV
Known
Kyphoscoliosis
Spinal cord injury ≥ C4, Bilateral diaphragm paralysis
MND, Post Polio, Spinal muscular atrophy (SMA)
Duchenne, Beckers, Myotonic, Pompe’s
Central Alveolar Hypoventilation
Obesity hypoventilation
Possible
Cardiac failure
Stroke
Suppurative Lung disease
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What stops you from breathing?
Fatigue – Energy supply < Energy demand
Energy supply depends on
Inspiratory muscle blood flow
Blood energy and O2 substrate
Cellular function to extract and use energy
Energy demands depend on
Pressure required, time of work, efficiency of muscles and breathing system
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Lungs go up and down…
Increased PaCO2
Muscle weakness
Increased WOB
Diaphragm dysfunction
Decreased Vt
Alveolar hypoventilation
Shunt
Hypoxia
Low V/Q
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When does respiratory failure develop
Restriction
Principally a restrictive lung
problem
Failure to move enough air
in and out
In different stages of sleep
breathing is progressively
reduced
Sleep
Hypoventilation
Hypoxaemia
Hyperapnoea
Cortical inputs
Respiratory centre sensitivity
Chemoreceptor sensitivity
SLEEP
Lung mechanics
Respiratory muscle
contractility
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Presentation of Respiratory Failure
Expected
Increasing SOB
Orthopnoea
Increased frequency and severity of chest infections
Poor sleep
Headache
Daytime somnolence
Weight loss / decreased appetite
Emergency
Unable to wean from
acute ventilatory support
Cor pulmonale
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Aims and Goals
Aims
Improved gas exchange
Optimized lung volume
Reduced work of breathing
Correct hypoxaemia
Correct acidosis
Reverse atelectasis
Rest respiratory muscles
Goals
Increase life
Promote independence
Decrease morbidity
Decrease hospital
admissions
Improve quality of life
Be cost effective
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Mouth Ventilator
Pres = V’.Rrs
Pel = ΔV.Ers
Pmus
Palv>0Palv=<0
Spontaneous ventilation (or NPVish) Mechanical ventilation
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Poes Poes
Spontaneous breathing Spontaneous breathing CPAP 15cm H20
-20 -20
AOAO
LV 100-20 -5
LV 100
Ptm=100-(-20)=120 Ptm=100-(-5)=105
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What do we do about it
Measure respiratory function at time of diagnosis
Monitor change in physical parameters and
correlate them with the person
Inform the patient about the options of
respiratory support
Work as part of the team to provide support in all
aspects of the disease
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How do we do it?
Symptoms
Epworth Score
>9 investigate, >11
abnormal, >15 small
children
Headache
LRTI
Weight loss
Cough
Muscle weakness
FEV1 / FVC <60% expected
SNIP < -60 H2O
Poor cough
Decreased voice
Orthopnoea
Fluoroscopy diaphragm
Bulbar problems affect measurement
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How do we do it?
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Before
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After
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How is it done?
NON INVASIVE
• Nocturnal to ~16h
day
• Bulbar function
• Facemask
• Nasal mask / pillows
• Mouthpiece
• Bilevel turbine with
leak from CO2
elimination
INVASIVE (trach)
• >16h day
• Poor bulbar
function
• Uncuffed trachey
• Complex ventilators
pressure control to
allow for leak
• Prolonged insp time
for speech
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NIV
Ventilates predominantly upper lobes / zones
Does prevent atelectasis
Need assisted cough
Efficiency of ventilation OK
Nasal bridge breakdown
Cumbersome / cosmetic issues
Speech takes time
Frog breathing, Sipping from ventilator allow increased periods off vent
Invasive
Ventilate all lobes
PEEP to prevent atelectasismay not be required
Allows access to airway
Speech well maintained
Can alternate cuffed and uncuffed
Carer demands greater
Costs perceived as greater
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Assisted cough
You are going to see a lot more of these..
Rapid insufflation with high
pressures
Negative pressure abruptly
Moves secretions
“it was like having my lungs
pulled out through my
throat…”
Need to get secretion out
of oropharynx too
Other models are
available..
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Diaphragmatic pacing
Works in quadraplegic
patients
Trials beginning in
ALS/MND
May delay the need for
ventilation in progressive
disease
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What is weaning
Weaning is…
Spontaneous breathing
Discontinuation of mechanical ventilation and the removal of an artificial airway
Weaning begins at the time of the first spontaneous breathing trial (SBT)
Difficult weaning > 3 SBT or >7 days after first SBT
Prolonged mechanical ventilation >21 days with more than 6 hrs mechanical ventilation / day
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When to wean?
Recovered from illness
Adequate gas exchange
Appropriate neuromuscular function
Stable CV function
Weaning may represent 40% of ventilated time
Start to wean as soon as the ETT goes in
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Who decides when someone is
ready?
Daily screening / daily interruption of sedation
Protocol screening and susbsequent SBT not by
doctors (Ely 1996 )
Generally aim to be on the minimum supprot
necessary
Weaning may be entering a new era (Metha et
al JAMA 2012)
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How do you assess if someone is
ready to wean?Objective
PaO2/FiO2 >150-200
PEEP 5-8 cm H20
FiO2 <0.5
pH > 7.25
RR < 30 – 38 BPM
Vt 4-6 ml/kg
RSBI (RR/Vt) 60-105
Subjective
Haemodynamic stability
Absence of myocardial
ischaemia
Minimal vasopressors CV instability
Improving CXR
Adequate muscle strength
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Spontaneous breathing trial
Dip toe in water
Pass SBT 60 – 80% chance
of extubation
T-piece
CPAP 5
PS 7
30 60 or 120 minutes
Signs of failure
SpO2 <90%
PaO2 <6-8 Kpa
pH<7.32
Increase in PaCO2 1.5 Kpa
RR>30, Increased by >50%
CV instability
Depressed deteriorating GCS
Sweating discomfort
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Consequences of delay
Delayed extubation
Increased VAP, airway
trauma, ICU stay
Failed extubation / reintubation
Failed reintubation
8x increase in nosocomial
pneumonia
6-12x increase in mortality
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How to become a weaner
king…
Minimum support required right from start
Look to reduce support all day every day
But don’t reduce at night
Look to minimise sedation
Have a plan – unit protocol or bespoke
Make it someone’s responsibility
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1994 Frequent LRTI, Headaches, day time sleepiness, poor appetite
NIV secretions / plugging
1996 Tracheostomy
Initially the tracheotomy was quite uncomfortable and difficult to breathe with,
which was scary.
However, after a few months’ recovery and adjustment I suddenly had a new
lease for life. I had more energy, it was easier to talk, my appetite improved
dramatically, more importantly secretions could be easily suctioned from my lungs
through the tracheotomy, significantly reducing chest infections.
It definitely was the correct decision as it has allowed me to survive with a good
quality of life for much longer.
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A Life worth living
Holidays / air travel
Concerts
Independent living
University
Aiming for 4th and 5th decades
www.alifeworthlivingfilm.com
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A life worth living…
Patients should not be denied access to
healthcare
Quality and quantity of life are unknown
Post op care should focus on the elements of
disability as much as physiological and operative
concerns