High Definition Radiotherapy - ALATRO 2017€¦ · 1 DeSantis CE, Cancer treatment and survivorship...
Transcript of High Definition Radiotherapy - ALATRO 2017€¦ · 1 DeSantis CE, Cancer treatment and survivorship...
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Not available for sale in all markets
Dara Chhit AMS Product Marketing November 7, 2017
High Definition Radiotherapy
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Not available for sale in all markets
Cleverson Lopes Marketing Manager LA November 7, 2017
High Definition Radiotherapy
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Varian Medical Systems
General Linac Fair Balance Safety Statement
Intended Use Summary
Varian Medical Systems’ linear accelerators are intended to provide stereotactic radiosurgery and precision radiotherapy
for lesions, tumors, and conditions anywhere in the body where radiation treatment is indicated.
Important Safety Information
Radiation treatments may cause side effects that can vary depending on the part of the body being treated. The most
frequent ones are typically temporary and may include, but are not limited to, irritation to the respiratory, digestive, urinary
or reproductive systems, fatigue, nausea, skin irritation, and hair loss. In some patients, they can be severe. Treatment
sessions may vary in complexity and time. Radiation treatment is not appropriate for all cancers.
Medical Advice Disclaimer
Varian as a medical device manufacturer cannot and does not recommend specific treatment approaches. Individual
treatment results may vary.
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GROWTH IN SRS SRS/SBRT National Forecast, U.S. Adult Market
• Technology innovation
• Increased survival and
need for retreatment
• Cost pressure
* Source: Sg2 Consulting, Skokie, Illinois, U.S.
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CLINICAL RATIONAL: TREND TOWARDS SRS
• SRS is recommended by NCCN as a primary treatment option for brain
metastases (including n>4).2
• Approximately 20 percent of newly diagnosed cancer patients will develop
brain metastases.1
• An increasing number of patients with brain metastases return for
retreatment.3
• Modern outcomes suggest adverse effects from WBRT on patient cognition
and quality of life. Practice is evolving to SRS alone in patients with up to 4
brain metastases.4
1 DeSantis CE, Cancer treatment and survivorship statistics, 2014 CA. 2 Nabors LB et al. Central Nervous System Cancers, Version 2.2014. J Natl Compr Canc Netw. 2014. 3 Nieder C et al. Presentation, patterns of care, and survival in patients with brain metastases: what has changed in the last 20
years? Cancer. 2011. 4 Sahgal A et al. Stereotactic radiosurgery alone for multiple brain metastases? A review of clinical and technical issues. Neuro
Oncol. 2017 NOT AVAILABLE FOR SALE IN ALL MARKETS
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HYPERARC High-definition radiotherapy for more patients
•Prescribed Immobilization
•Virtual dry run
•Imaging waypoints
Safe*
•Rapid dose fall-off
•SRS NTO
•Optimized collimator angle
Compact Dosimetry
•Automated workflow
•Simplified planning process
•SRS in conventional timeslots
Efficient
*Designed for patient collision prevention NOT AVAILABLE FOR SALE IN ALL MARKETS
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PRESCRIBED IMMOBILIZATION AND SET-UP
• Immobilization device
modeled in Eclipse™
• Patient Protection Zone
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CREATE NON-COPLANAR PLAN WITHIN MINUTES*
Defining plan geometry and target doses
• Up to ten prescription doses
• Automatic lower dose objectives
• SRS NTO – Eliminates need to define upper
objectives or to create the shell
structures
.
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CREATE NON-COPLANAR PLAN WITHIN MINUTES* Auto isocenter placement and trajectory selection
• Isocenter placement based on
center of mass of selected target
volumes
• SRS-specific target quality metrics
calculated automatically
* Varian Summative usability test report. All participants
were able to create HyperArc plan within 8 minutes,
review HyperArc plan within 3 minutes and verify
automated delivery or modify plan within 5 minutes.
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CREATE NON-COPLANAR PLAN WITHIN MINUTES* Optimized collimator angle for each arc
• Reduction of plan complexity
• Minimal interaction between
targets
• Each target has its own ‘lane’
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VIRTUAL DRY RUN: COLLISION PRE-CHECK
• Accurate 3D animation of
delivery sequence
• Distance between gantry and
patient protection zone is
displayed and color-coded
• Only collision-free plans
allowed for automated delivery
HYPERARC PLANNING IS 510(K) PENDING. NOT AVAILABLE FOR SALE IN ALL MARKETS
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AUTOMATED One-click delivery
• CBCT enforced for precise patient
setup
• MV imaging available for
verification
• Optimized treatment delivery order
w/o need to re-enter the room
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TREATMENT DELIVERY
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RAPID DOSE FALL-OFF Increasing dose compactness by distributing more beams around the patient
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Coplanar RapidArc® Non-coplanar RapidArc®
Prescription, 20Gy
HyperArc™ HDRT
50% prescription, 10Gy
4Gy
Image courtesy of NHS Greater Glasgow and Clyde
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RAPID DOSE FALL-OFF: COMPARING PLANS 4Gy
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• HyperArc plan (left)
• Typical non-coplanar RapidArc
SRS plan (right)
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OFFER RADIOSURGERY TO MORE PATIENTS
Safe* • Virtual dry run
• Prescribed Immobilization
• Imaging waypoints
Compact • Rapid dose fall-off
• SRS NTO
• Optimized collimator angle
Efficient • Automated workflow
• Simplified planning process
• SRS in conventional timeslots NOT AVAILABLE FOR SALE IN ALL MARKETS *Designed for patient collision prevention
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Over the last five years, our radiosurgery plan quality has improved to
equal or exceed our Gamma Knife. Physicians and patients preferred the
frameless and highly efficient delivery on our TrueBeam and Edge systems
and our Gamma Knife was decommissioned June 2017. HyperArc
planning automates much of the radiosurgery treatment planning strategies
that we have implemented at UAB and could enable more clinics to
perform higher quality radiosurgery for more patients.
John Fiveash, M.D., professor and vice chair for academic programs in the UAB Department of Radiation Oncology
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En los últimos cinco años, la calidad de nuestro plan de radiocirugía ha
mejorado para igualar o superar nuestro Gamma Knife. Los médicos y
pacientes prefirieron la entrega sin marco y altamente eficiente en
nuestros sistemas TrueBeam y Edge y nuestro Gamma Knife se retiró de
servicio en junio de 2017. La planificación de HyperArc automatiza gran
parte de las estrategias de planificación de tratamiento de radiocirugía que
hemos implementado en la UAB y podría permitir que más clínicas hagan
radiocirugía para más pacientes.
John Fiveash, M.D., professor and vice chair for academic programs in the UAB Department of Radiation Oncology
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THANK YOU