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Transcript of Herbs for immune_season_warner
Herbal Assistance During the Winter Immune Season
Dr Wendy Warner MD ABIHM
Disclosure bull Scientific Advisory Board ndash Gaia Herbs
Planning Ahead bull Eating well now bull Getting the right amounttype of exercise bull Sleep how much how restful bull Shutting down the brain chatter bull Basic common sense hygiene etc bull Better gut health probiotics prebiotics
fermented foodsdrinks
Eating for Immune Boosting bull Increase Omega 3 fatty acids
ndash Reduces IL-1 and TNF alpha bull Decrease glycemic load
ndash Reduces IL-1 IL-6 and TNF alpha
Exercise bull Enough to lead to weight loss
ndash Reduces adipose tissue therefore lowers inflammation
bull Enough to lower cortisol ndash Can elevate both pro- and anti-inflammatory
cytokines
bull Beware overdoing exercise ndash Can put cortisol on overdrive which creates
inflammation increases adipose
Shutting Down the Brain Chatter bull Meditation has been shown to reduce IL-1 IL-
6 and TNF alpha
Shifting Emotions bull IgA levels affected for more than 6 hours by
only 5 minutes of strong emotion ndash 5 minutes of carelove improved IgA levels ndash 5 minutes of anger dropped IgA levels below
baseline for more than 6 hours
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Disclosure bull Scientific Advisory Board ndash Gaia Herbs
Planning Ahead bull Eating well now bull Getting the right amounttype of exercise bull Sleep how much how restful bull Shutting down the brain chatter bull Basic common sense hygiene etc bull Better gut health probiotics prebiotics
fermented foodsdrinks
Eating for Immune Boosting bull Increase Omega 3 fatty acids
ndash Reduces IL-1 and TNF alpha bull Decrease glycemic load
ndash Reduces IL-1 IL-6 and TNF alpha
Exercise bull Enough to lead to weight loss
ndash Reduces adipose tissue therefore lowers inflammation
bull Enough to lower cortisol ndash Can elevate both pro- and anti-inflammatory
cytokines
bull Beware overdoing exercise ndash Can put cortisol on overdrive which creates
inflammation increases adipose
Shutting Down the Brain Chatter bull Meditation has been shown to reduce IL-1 IL-
6 and TNF alpha
Shifting Emotions bull IgA levels affected for more than 6 hours by
only 5 minutes of strong emotion ndash 5 minutes of carelove improved IgA levels ndash 5 minutes of anger dropped IgA levels below
baseline for more than 6 hours
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Planning Ahead bull Eating well now bull Getting the right amounttype of exercise bull Sleep how much how restful bull Shutting down the brain chatter bull Basic common sense hygiene etc bull Better gut health probiotics prebiotics
fermented foodsdrinks
Eating for Immune Boosting bull Increase Omega 3 fatty acids
ndash Reduces IL-1 and TNF alpha bull Decrease glycemic load
ndash Reduces IL-1 IL-6 and TNF alpha
Exercise bull Enough to lead to weight loss
ndash Reduces adipose tissue therefore lowers inflammation
bull Enough to lower cortisol ndash Can elevate both pro- and anti-inflammatory
cytokines
bull Beware overdoing exercise ndash Can put cortisol on overdrive which creates
inflammation increases adipose
Shutting Down the Brain Chatter bull Meditation has been shown to reduce IL-1 IL-
6 and TNF alpha
Shifting Emotions bull IgA levels affected for more than 6 hours by
only 5 minutes of strong emotion ndash 5 minutes of carelove improved IgA levels ndash 5 minutes of anger dropped IgA levels below
baseline for more than 6 hours
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Eating for Immune Boosting bull Increase Omega 3 fatty acids
ndash Reduces IL-1 and TNF alpha bull Decrease glycemic load
ndash Reduces IL-1 IL-6 and TNF alpha
Exercise bull Enough to lead to weight loss
ndash Reduces adipose tissue therefore lowers inflammation
bull Enough to lower cortisol ndash Can elevate both pro- and anti-inflammatory
cytokines
bull Beware overdoing exercise ndash Can put cortisol on overdrive which creates
inflammation increases adipose
Shutting Down the Brain Chatter bull Meditation has been shown to reduce IL-1 IL-
6 and TNF alpha
Shifting Emotions bull IgA levels affected for more than 6 hours by
only 5 minutes of strong emotion ndash 5 minutes of carelove improved IgA levels ndash 5 minutes of anger dropped IgA levels below
baseline for more than 6 hours
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Exercise bull Enough to lead to weight loss
ndash Reduces adipose tissue therefore lowers inflammation
bull Enough to lower cortisol ndash Can elevate both pro- and anti-inflammatory
cytokines
bull Beware overdoing exercise ndash Can put cortisol on overdrive which creates
inflammation increases adipose
Shutting Down the Brain Chatter bull Meditation has been shown to reduce IL-1 IL-
6 and TNF alpha
Shifting Emotions bull IgA levels affected for more than 6 hours by
only 5 minutes of strong emotion ndash 5 minutes of carelove improved IgA levels ndash 5 minutes of anger dropped IgA levels below
baseline for more than 6 hours
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Shutting Down the Brain Chatter bull Meditation has been shown to reduce IL-1 IL-
6 and TNF alpha
Shifting Emotions bull IgA levels affected for more than 6 hours by
only 5 minutes of strong emotion ndash 5 minutes of carelove improved IgA levels ndash 5 minutes of anger dropped IgA levels below
baseline for more than 6 hours
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Shifting Emotions bull IgA levels affected for more than 6 hours by
only 5 minutes of strong emotion ndash 5 minutes of carelove improved IgA levels ndash 5 minutes of anger dropped IgA levels below
baseline for more than 6 hours
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
One Concept of Immune Function and its Organization
bull Surfacenonspecific Immune Response ndash Physical barrier breaks activates kinins
proinflammatory cytokines (IL-1 IL-6 TNF alpha IL-8) ndash Secretory system (phagocytes monocytes
neutrophils macrophages) bull InternalSpecific Immune Response
ndash Cell mediated (Th1 T helper T suppressor T cytotoxic lympokines) Cytokines produced
ndash Humoral (B cells Th2) antibodies produced bull Endocrine Immune Response bull Immune Reservoir
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Surface Nonspecific bull Echinacea bull Yarrow bull Demulcents
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Internal Specific bull Cell mediated
ndash Ganoderma (Reishi ) ndash Lonicera (Honeysuckle) ndash Garlic
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Internal Specific bull Humoral
ndash Stimulate activity bull Echinacea bull Elderberry
ndash Reduce excess activity bull Scutellaria bull Turmeric bull Bupleurum bull Immune amphoterics
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Endocrine Immune Response bull HPA axis has direct effect on immune system
ndash Adaptogens ndash Nervines
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Immune Reservoir bull Doesnrsquot exist per se bull Overall ability to mount immune response bull Immune potentiators
ndash Ganoderma ndash Grifola ndash Astragalus ndash Chaga
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Others bull Immune Amphoterics
ndash Normalize immune response
bull Alteratives ndash Increase resistance by improving eliminatory
function and circulation
bull Lymphatic Tonics ndash Improve lymphatic circulation and drainage
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Echinacea bull Nonspecific and humoral
immunity bull Use early in acute infection bull Not for daily use bull Best for respiratory illnesses to
reduce duration and severity of symptoms
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanism of Action Echinacea bull Stimulates production of IL-6 TNF IL-12 and
NO from macrophages in vitro bull Initiates a signaling cascade within
macrophages through both TLR4-dependent and -independent mechanisms involving ERK p38 and JNK and ultimately the activation of NF-kappaB
bull Sullivan AM1 Laba JG Moore JA Lee TDImmunopharmacol Immunotoxicol 200830(3)553-74
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Echinacea bull Tincturemdash(1225) 40-60 drops every 2-3
hours bull Dry herb and root 2-3 gram daily bull Liquid Extract of root 12 3-10 mls daily bull Echinacea purpurea juice of fresh plant 6-9mls
daily
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Honeysuckle (Lonicera japonica) bull Internal specific immunity bull In TCM clears blood heat (infections)
including high fevers from strep throat pneumonia sinusitis bronchitis
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanism of Action Honeysuckle bull In combination with forsythia appears to
activate host defense system as well as directly inhibit virus proliferation
ndash Integr Biol (Camb) 2013 Feb 5(2)351-71
bull Might increase neutrophil activity and increase phagocytosis
ndash Natural medicines database
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Honeysuckle bull Tincturemdash(14) 30-40 drops qid
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Forsythia (Forsythia suspensa) bull Antibacterial bull Antiviral bull Anti-inflammatory bull Antioxidant bull Immunoregulatory bull In Chinese medicine removes toxic heat
(infections) in the blood and respiratory systems
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanism of Action Forsythia bull In Influenza colds viral pneumonia
bronchitis sinusitismdashappears to be antiviral bull Used in China with licorice houttuynia and
honeysuckle to treat SARS
bull J Ethnopharmacol 2006 Sep 19107(2)205-10 bull J Med Plants Res 20104(14)1455-8
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Forsythia bull Tincturemdash(14 or 15) 15-30 drops tid bull Tea (decoction)mdash12 dried seedpods 8
ounces water decoct 10 min then steep 15-20 min Up to 2 cups daily
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Andrographis (Andrographis paniculata)
bull Internalhumoral stimulatory action bull Antiviral bull Antibacterial bull Good for influenza
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanism of Action Andrographis
bull Anti-inflammatory bull Immunostimulant bull Antipyretic
bull E Ernst Planta Med 2004 70 294-298
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Andrographis bull Tincturemdash(14) 20-40 drops qid bull Adult 2-3 grams daily 4-6mls 12 extract bull Acute infection use 6 grams daily or up to 12mls
daily bull Combine with warming herbs such as ginger
cinnamon and astragalus bull Children 5-1 gram daily 5 ndash 2 mls extract bull Acute infection use 2 grams daily and 4 mls 12
extract
bull Warning very bitter
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Black Elderberry (Sambucus nigra) bull Antiviral bull Increases inflammatory and anti-inflammatory
cytokines bull Significant studies show faster recovery from
influenza bull Syrups most common
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanism of Action Elderberry bull Blocks viral attachment to host cell bull Increases inflammatory cytokines
ndash IL-1 IL-6 IL-8 TNF alpha
bull Increases anti-inflammatory cytokines ndash IL-10
bull Eur Cytokine Netw 2001 Apr-June12(2) 290-6
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Elderberry bull Tincture (1115) 60-90 qid bull Also historically used in syrups jams cordials and
wines bull Elderberry fruit syrups- standardized to 30-38
percent elderberry bull Powdered extracts- 500 mg (capsule) 2-3 times
daily for 3-4 days bull Liquid form dosed at one tablespoonful (15 mL)
three times daily bull Acute viral infections- treat at least three days
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Turmeric (Curcuma longa) bull Many many modes of action bull Internalhumoral activity bull Decreases excess humoral activity bull Anti-inflammatory antioxidant antibacterial
antitumor
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanisms of Action Turmeric bull Inhibits neutrophil function bull Inhibits lymphocyte activity bull Inhibits NF-kB bull (and others)
bull Mol Nutr Food Res 2013 57 1529-42 bull Adv Pharmacol Sci 7pp
dxdoiorg1011552013805756
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Turmeric bull Tincturemdash(12) 40-60 drops qid bull General use 15 - 75 mg of Curcumin daily in 3-4
divided doses bull As a tea 1-15g of dried root may be steeped in
150 mL of water for 15 minutes taken 2-3x daily bull Antioxidant two 500 mg oral doses daily use for
three months
bull Absorption enhanced by addition of black pepper
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Reishi (Ganoderma lucidum) bull Adaptogenic bull Immune potentiator bull Anti-inflammatory bull Antioxidant bull ldquoImmune amphotericrdquo bull Good for allergies
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanism of Action Reishi bull Stabilizes mast cells reduces histamine
response bull Improves innate regulatory capacity bull Stimulates TNF alpha IL-1 IL-6 Th1 T
lymphocytes bull Nervine
bull Nutr Cancer 200553(1)11-7
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Reishi bull Tincturemdash(15) 80-100 drops 4-6x daily bull Decoctionmdash1-2 oz dried mushroom to 32 oz
water Decoct 2-4 hrs Up to 4 cups daily bull 30mlsday15 liquid extract bull 6-12 g dry powder bull 5-1gday concentrated extract
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Astragalus (Astragalus membranaceus) bull Immune potentiator
immune amphoteric bull Immunosuppressive for
cancer bull Used for immune excess as
well (allergies) bull In Chinese medicine
enhances the wei qi which suppresses sweating and helps fight external infections of the lungs
bull Prevents but doesnrsquot really treat acute viralbacterial infections
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Mechanism of Action Astragalus bull Potentiates IL-2 and monocyte activity bull Enhance NK cell activity bull Modulates TNF alpha
bull Clin Nephrol 1999 Nov52(5)333-4 bull J Clin Lab Immunol 198826183-7 bull American Herbal Pharmacopoeia 199911-25
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Dosing Astragalus bull Tincture-- (15) 40-80 drops tid bull Decoction-- 2 tbl dried root to 12 oz water Up
to 3 cups per day bull 10-30 grams dry root bull 5-10 mls day of 13 liquid extract bull Or cook with it (soup)
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Adaptogens and Nervines bull Ashwaganda bull Holy Basil bull Rhodiola bull Ginsengs bull Lemon Balm bull Milky Oats
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Immune Potentiators bull Reishi bull Maitake bull Licorice bull Eleutherococcus bull Cordyceps
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Alteratives bull Hoxsey (as published in 1956)
ndash Barberry buckthorn bark burdock root cascara sagrada licorice root poke root prickly ash red clover blossoms and stillingia root in a water base with potassium iodide
bull Scudders ndash Corydalis alder bark mayapple fig wort yellow
dock
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Lymphatic Tonics bull Red clover bull Cleavers bull Poke bull Burdock bull Fig wort bull Violet
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Getting These Herbs to Patients bull Consider dispensing these herbs in clinic versus
referring patients to retail Why ndash Consumers have no good mechanism to validate
quality of brandsproducts you are the filter ndash Once you send patients to ldquofend for themselvesrdquo you
do not know if they ever bought the product or worse if they bought a lower quality product
bull Alternative approach is to utilize a patient direct shipping option
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
All Botanicals are Not Created Equal bull 5 Pillars of Quality Botanicals ndash varies by
manufacturer ndash Design Evidence-based formulation amp appropriate dosage
form ndash Authenticity Ingredient identity is always verified using
validated methods ndash Potency Ingredient amp finished product potency is verified
using validated methods ndash Purity Proven freedom from biological amp chemical
contaminants ndash Validation Evidence of safety and efficacy for intended
use
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Questions to Ask Manufacturers 1 Do you buy your herbal raw materials directly from the grower
or from an intermediary supplier 2 Do you grow any of your own botanicals 3 How do you validate herbal raw material genus and species 4 Are your herbal ingredients organic Are they ecologically wild
harvested 5 What solvents do you use to extract your herbs 6 Are you Prop 65 compliant 7 Can you provide test results for your products showing results
of heavy metal tests testing for pesticides and other contaminants
8 How do you validate potency Can you provide results of potency testing
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Botanical Medicine Resources bull Links for study and institutions
ndash American Botanical Council httpabcherbalgramorg ndash American Herbal Products Association
httpwwwahpaorg ndash Natural Medicines (formerly Natural Standard)
httpsnaturalmedicinestherapeuticresearchcom ndash Henriettersquos Herbal Homepage
httpwwwhenriettesherbalcom ndash Herb Research Foundation
httpwwwherbsorgherbnews ndash Dr Dukes Database (Phytochemical Database)
httpwwwars-gringovduke ndash Gaia Herbs Professional Solutions
wwwgaiaprofessionalcom
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Botanical Medicine Resources bull Herb books
ndash Principles and Practice of Phytotherapy- Modern Herbal
Medicine Simon Mills and Kerry Bone ndash Healing with Whole Foods- Oriental Traditions and Modern
Tradition Paul Pitchford ndash Medical Herbalism and The New Holisitc Herbal David Hoffman ndash Womenrsquos Encyclopedia of Natural Medicine Dr Tori Hudson ndash Encyclopedia of Natural Healing for Children and Infants Dr
Mary Bove ndash Adaptogens in Medical Herbalism Donald Yance ndash Botanical Medicines for Womenrsquos Health Dr Aviva Romm ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona
Low Dog
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Botanical Medicine Resources bull Herb books (continued)
ndash National Geographicrsquos Guide to Medicinal Herbs Dr Tieraona Low Dog
ndash Integrative Womenrsquos Health Low Dog and Maizes ndash Botanical Safety Handbook AHPA ndash Textbook of Natural Medicine Pizzorno and
Murray ndash Herbal Medicines in Pregnancy and Lactation
Mills Dugoua Perri Koren
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Botanical Medicine Resources bull Publications
ndash Herbal Gram ndash American Botanical Council ndash Townsend Letter ndash Integrative Medicine A Clinicianrsquos Journal ndash Journal of Alternative and Complementary
Medicine
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-
Thank You
- Herbal Assistance During the Winter Immune Season
- Disclosure
- Planning Ahead
- Eating for Immune Boosting
- Exercise
- Shutting Down the Brain Chatter
- Shifting Emotions
- One Concept of Immune Function and its Organization
- Surface Nonspecific
- Internal Specific
- Internal Specific
- Endocrine Immune Response
- Immune Reservoir
- Others
- Echinacea
- Mechanism of Action Echinacea
- Dosing Echinacea
- Honeysuckle (Lonicera japonica)
- Mechanism of Action Honeysuckle
- Dosing Honeysuckle
- Forsythia (Forsythia suspensa)
- Mechanism of Action Forsythia
- Dosing Forsythia
- Andrographis (Andrographis paniculata)
- Mechanism of Action Andrographis
- Dosing Andrographis
- Black Elderberry (Sambucus nigra)
- Mechanism of Action Elderberry
- Dosing Elderberry
- Turmeric (Curcuma longa)
- Mechanisms of Action Turmeric
- Dosing Turmeric
- Reishi (Ganoderma lucidum)
- Mechanism of Action Reishi
- Dosing Reishi
- Astragalus (Astragalus membranaceus)
- Mechanism of Action Astragalus
- Dosing Astragalus
- Adaptogens and Nervines
- Immune Potentiators
- Alteratives
- Lymphatic Tonics
- Getting These Herbs to Patients
- All Botanicals are Not Created Equal
- Questions to Ask Manufacturers
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Botanical Medicine Resources
- Thank You
-