Hemophilia and ALD

Hemophilia and ALD

By: Maricela Navarro, Essance Ward

& Asia Thomas

By: Maricela Navarro, Essance Ward

& Asia Thomas

The Genetics of Hemophilia and Symptoms:The Genetics of Hemophilia and Symptoms:

• Only the X chromosome carries the genes related to clotting factors.

• A male who has the abnormal gene on his X chromosome will have it.

• A female must have the abnormal gene on both of her X chromosomes to have it, which is very rare.

• Symptoms are excessive bleeding, bleeding in the joints, and in the brain.

• Those who have severe hemophilia may bleed spontaneously.

• Only the X chromosome carries the genes related to clotting factors.

• A male who has the abnormal gene on his X chromosome will have it.

• A female must have the abnormal gene on both of her X chromosomes to have it, which is very rare.

• Symptoms are excessive bleeding, bleeding in the joints, and in the brain.

• Those who have severe hemophilia may bleed spontaneously.

Some Facts about Hemophilia:Some Facts about Hemophilia:

• About 18,000 people in the U.S. have it.

• 400 babies are born with the disorder every year.

• This disorder usually occurs in males.

• About 18,000 people in the U.S. have it.

• 400 babies are born with the disorder every year.

• This disorder usually occurs in males.

Problems Person Has Because of the Disease:Problems Person Has Because of the Disease:

HemophiliaThey are unable to control blood

clotting.

HemophiliaThey are unable to control blood

clotting.

Treatment and Prognosis:Treatment and Prognosis:

• Treatment centers• Avoid Ibuprofen• Stay away from sharp corners• Good lifestyle, almost normal• 1,681 deaths per year

• Treatment centers• Avoid Ibuprofen• Stay away from sharp corners• Good lifestyle, almost normal• 1,681 deaths per year

Adrenoleukodystrophy (ALD)-Genetics of Disease and Symptoms:Adrenoleukodystrophy (ALD)-Genetics of Disease and Symptoms:

• This disorder is an X-linked genetic trait.

• This disorder is an X-linked genetic trait.

• Loss weight, hearing loss, hyper activity, and swallowing difficulties.

• Loss weight, hearing loss, hyper activity, and swallowing difficulties.

Some Facts:Some Facts:

• 1 in 20,000 people suffer from ALD of all races.

• Mostly males have this disorder.

• 1 in 20,000 people suffer from ALD of all races.

• Mostly males have this disorder.

Problems Person Has Because of ALD:Problems Person Has Because of ALD:• The body is unable to break down

certain fat molecules.ALD

• The body is unable to break down certain fat molecules.

ALD

Treatment and Prognosis:Treatment and Prognosis:

• Physical therapy, psychological support, special education, Lorenzo's oil, and steroids are all treatments.

• Death usually occurs 1-10 years after the onset of symptoms.

• Physical therapy, psychological support, special education, Lorenzo's oil, and steroids are all treatments.

• Death usually occurs 1-10 years after the onset of symptoms.

What we all did:What we all did:

• Essance found the information on the ALD disorder.

• Maricela found the information on the hemophilia disorder.

• Asia put the information together on the power point.

• Essance found the information on the ALD disorder.

• Maricela found the information on the hemophilia disorder.

• Asia put the information together on the power point.

Sources:Sources:• http://www.youtube.com/watch?

v=CxkylRxJxh8&feature=related• www.umm.edu/ency/article/001182trt.htm• http://www.youtube.com/watch?

v=F0ZoEGnTAM0• http://health.nytimes.com/health/guides/

disease/adrenoleukodystrophy/overview.html

• http://www.wrongdiagnosis.com/a/adrenoleukodystrophy/prevalence.htm

• http://www.youtube.com/watch?v=CxkylRxJxh8&feature=related

• www.umm.edu/ency/article/001182trt.htm• http://www.youtube.com/watch?

v=F0ZoEGnTAM0• http://health.nytimes.com/health/guides/

disease/adrenoleukodystrophy/overview.html

• http://www.wrongdiagnosis.com/a/adrenoleukodystrophy/prevalence.htm