hemato.doc
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1)What is corrected reticulocyte count
Ans - retic count X observed HCT/ normal HCT
2)what is the most sensisitive and specific marker for Fe defeciency
Ans soluble transferrin saturation level
3)what are three hall marks of tumour lysis syndrome
Ans. Hyper uricemia, hyper phosphatemia and hyperkalemia and hypocalcemia
4)what is the once daily oral iron chelator known as
Ans -deferasirox
5 ) who was the first person to describe sickle cell anemia ?
Ans - Herrick
6) most common leukemia in downs syndrome
Ans ALL
7) most common AML in downs syndrome
AML M7
8) anti oxidant used for reducing cardio toxicity of daunorubicin
Ans - desrozaxane
9) what is the new model for coagulation called Ans - cell based model. Most of the coagulation occurs on the surface of platelets
10) haemolytic anemia where iron is indicated Ans - PNH
11) congenital Aplastic anemia with dystrophic nail changes
Ans -dyskeratosis congenita
15)what is duncan syndrome ?
Ans - X-linked lympho proliferative disease
16)thrombo poitin analogues used in ITP
Ans -El thrombopag and romiplastin
17)commonest malignancy seen in HIV children
Ans - NHL
18)commonest congenital prothrombotic condition
Ans -Factor V leiden
19)drug of choice in in BCR Abl acute leukemia and cML Ans -Imatinib myselate
20) langerin cell is seen in Ans - langerhans cell histiocytosis CD 207