HELLP Concept Map Revised
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Transcript of HELLP Concept Map Revised
HELLP!HemolysisElevated Liver EnzymesLow Platelet Count
Dx and TxDx is confirmed with CBC w/ platelet count and liver enzymesTx includes NST/ BPP to monitor fetus, administration of corticosteroid (Betamethasone) to improve fetal lung maturity, delivery (C/S if plt ct is greater than 40,000) regardless of gestational age, administration of blood products as indicatedSymptoms usually resolve within 1-3 days of successful delivery
Signs and SymptomsRight upper quadrant Pain
Nausea/ VomitingFatigue/ MalaiseHeadacheVisual disturbances*May or may not also have high B/P and proteinuria
Elevated Liver Enzymes- Fibrin deposits obstruct hepatic blood flow and lead to hepatocellular injury, which then leads to an increase in AST/ ALT and swelling of the liver
Low Platelet Count- platelets aggregate at the sites of damage, resulting in low platelet count (less than 100,000). Fibrin is also released and deposited in large amounts
Cause- The exact cause is unknown although HELLP is usually considered a variant of pre-eclampsia. HELLP may still occur in with women with minimally elevated blood pressure and no proteinuria. Usually occurs 32-36 weeks gestation.
Hemolysis (destruction of RBC’s)- It is thought that RBC’s are distorted or fragmented during passage through small, damaged blood vessesls. The vascular damage is associated with vasospasms.
Thrombocytopenia- Can lead to DIC!