Hannes smarason next code-wuxi combined technologies
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Transcript of Hannes smarason next code-wuxi combined technologies
Bringing Together Core Technologies Unlocks Genomic Data to Improve Healthcare
Hannes Smarason Genome Sequencing |Personalized Medicine | Transforming Health Care
Clinical Use of Genome Sequencing Rapidly Expanding
The adop9on of genome sequencing technology is rapidly expanding as medical centers around the world embrace its u9lity in informing healthcare decisions—an emerging reality of personalized medicine.
Expansion Driven by Technology
• There are three important areas of technology that are driving the use of genomic data in healthcare: genome sequencing, genomic analysis tools, and database storage.
• The first of these – genome sequencing – has advanced to the point that it is more widely accessible, with the cost of sequencing at nearly $1,000 or less.
• This lower cost of genome sequencing has reached a cri9cal milestone to enable the use of sequencing as a mass-‐market product for medical care.
Expansion Driven by Technology
• The second and third core genomic technologies – genomic analysis tools and database storage – are in the midst of evolu9on.
• Their progress and integra9on are cri9cal for the next stage of adop9on of genomic data into health care.
AnalyEcs Central to Progress
• Genomic Analysis Tools: – Since the human genome was first sequenced more than a decade
ago, an increasingly robust body of research has showcased the links between muta9ons iden9fied in the genome and disease risk.
– Informa9cs tools have been developed by medical centers and genomics companies to apply to whole-‐genome samples.
– Increasingly, these genome analysis tools will need to adapt to the steady pace of new genomic linkages to disease and to operate at a level approaching “big data.”
Database Storage EssenEal to Inform Decision Making
• Database Storage for Human Genomes: – There are a growing number of robust databases of human
genomes, including data for healthy people or those with certain diseases.
– When properly analyzed, these databases offer the poten9al to provide the medical community with a reference library against which to compare gene9c data.
– Large-‐scale, high-‐quality databases are an essen9al element to cross-‐reference a pa9ent genome to guide more informed medical decisions.
Combined Leading Technologies Will Accelerate Progress
• Recently, two leading genomics companies, WuXi and NextCODE Health, have combined their technology capabili9es in these two areas. – WuXi has industry-‐leading capabili9es to analyze, store and manage the
vast amounts of genomic data. – NextCODE Health brings a leading-‐edge system for sequence-‐based
clinical diagnos9c applica9ons and genome analysis.
• The combina9on of WuXi’s founda9onal genomic database storage and management and NextCODE’s sophis9cated genome analysis tools will integrated the key components that are most rapidly evolving to apply genomics to medical care.
OpportuniEes Lie on the Horizon
• Ini9a9ves like this in the advance the state-‐of-‐the-‐art in genomic analysis and database storage brings us to the heart of helping the world to fully harness personalized medicine, and to providing tools directly to doctors to provide be\er diagnos9cs and treatments to pa9ents.
• The progress to date has been amazing. Yet the opportuni9es ahead are even more extraordinary to improve the speed, accuracy, and accessibility of genomic informa9on to improve human health.