Guide to Laboratory Practice Part

8/10/2019 Guide to Laboratory Practice Part

http://slidepdf.com/reader/full/guide-to-laboratory-practice-part 1/36

GUIDE TO LABORATORY PRACTICE IN

GENERAL PATOLOGICAL ANATOMY



GRODNO MEDICAL UNIVERCITYDEPARTMENT OF PATHOLOGICAL ANATOMY

GUIDE TO LABORATORY PRACTICE IN

GENERAL PATOLOGICAL ANATOMY

By Hryb Anton

Grodno 2006



METHODICS OF PERFORMING OF LABORATORY

WORKS

It i n!"!#ry $or #%% t&d!nt to b! '!%% (r!(#r!d t)!or!ti"#%%y $or !*!ry %#bor#tory 'or+ by

t&dyin, t)!-#ti" %it!r#t&r!. /not on%y t)i r!*i!' in"%&din, t)! -#t!ri#% #nd 1&!tion (r!!nt!d

in t)i t!#")in, #id # '!%% # %!"t&r! not! E*!ry %#bor#tory 'or+ -&t b! don! "#rryin, o&t3

4 An ind!(!nd!nt t&dy o$ -#"ro(r!(#r#tion by !t#b%i)in, t)! +ind o$ or,#n #nd -or()o%o,i"#%

!5(r!ion o$ (#t)o%o,i"#% #nd "o-(!n#tory (ro"!! #nd by (!r$or-in, t)! t#+ indi"#t!d int)i t!#")in, #id. &") # t)! ,ro&(in, o$ -#"ro(r!(#r#tion #""ordin, to !tio%o,y. -!")#ni- o$

d!*!%o(-!nt #nd -or()o%o,i"#% !5(r!ion o$ (#t)o%o,i"#% (ro"!!. !t"

2 A di"&ion on t)! in*!ti,#t!d -#"ro(r!(#r#tion. #n#%yin, o-! t)!or!ti"#% (rob%!- &nd!r

t!#")!r7 &(!r*iion8 !ti-#tin, t)! t&d!nt t)!or!ti"#% #nd (r#"ti"#% #"ti*ity. # '!%% # t)!ir

+no'%!d,!

9 A t&dy o$ )ito%o,i"#% %id!. !%!"tron -i"ro,r#() #nd ")!-!. r!"ordin, t)! r!&%t o$ t)!

'or+ in t)! %#bor#tory not! boo+

: An in*!ti,#tion #nd di"&ion o$ t)! r!&%t o$ "&rr!nt bio(y. &r,i"#% #nd #&to(y -#t!ri#% /in

t)! %#bor#tory or #&to(y roo-

; Pr!!nt#tion o$ t)! r!&%t o$ (!r$or-!d %#bor#tory 'or+ to t)! t!#")!r $or "&rr!nt "ontro%



EDUCATIONAL-TARGET QUESTIONS ON THE THEME: HISTORY OF

PATHOLOGICAL ANATOMY, METHODS OF INVESSTIGATION IN PATHOLOGICAL

ANATOMY.

4 To +no' )itori"#% (!riod o$ (#t)o%o,i"#% #n#to-y d!*!%o(-!nt. ,r!#t!t di"o*!ry #nd

"i!ntit in !#") (!riod

2 To +no' #i- #nd -!t)od o$ (#t)o%o,i"#% #n#to-y3 i #&to(y ii b#i" -i"ro"o(y /-#in

(rin"i(%! o$ (r!(#r#tion o$ -#t!ri#% $or )ito%o,y #nd )ito")!-itry iii (!"i#% -!t)odo$ -i"ro"o(y #nd t#inin, i* !%!"tron -i"ro"o(y * -o%!"&%#r -!t)od in (#t)o%o,i"#%

#n#to-y

9 Mor()o%o,i"#% in*!ti,#tion o$ bio(y <ind o$ bio(y

: To +no' &bdi*iion o$ (#t)o%o,i"#% #n#to-y

; To +no' tr&"t&r! o$ (#t)o%o,o#n#to-i" !r*i"! #nd tr&"t&r! o$ (#t)o%o,o#n#to-i"

d!(#rt-!nt

LABORATORY WORK № 1

4 Viitin, o$ (#t)o)ito%o,i"#% %#bor#tory D!-ontr#tion o$ )ito%o,i"#% %#b'#r! #nd t#,! o$

-i"ro%#d! (r!(#r#tion

2 D!-ontr#tion o$ #&to(y

9 Di"&ionFi. 1 E5#-(%! o$ (#t)o)ito%o,i"#% r!(ort



EDUCATIONAL-TARGET QUESTIONS ON THE THEME: NORMAL CELL

STRUCTURE. CELL IN!URY. DYSTROPHYES. PARENCHYMATOUSE

DYSTROPHYES.

THE BASIC QUESTIONS OF THE THEME:

4 To r!(!#t nor-#% "!%% tr&"t&r!

2 To +no' #!tio%o,y #nd (#t)o,!n!i o$ "!%% in=&ry

9 To +no' d!$inition o$ "on"!(t >dytro()i#>. it (rin"i(#% "#&!. -or()o,!n!ti"-!")#ni-

: To +no' #bo&t -or()o%o,i"#% (!"i$i"ity o$ dytro()i# #nd %!*!% on ')i") t)i

(!"i$i"ity i r!*!#%!d

; To ,i*! # ,!n!r#% ")#r#"t!riti" o$ (#r!n")y-#to& dytro()i# /d!$inition.

"%#i$i"#tion

6 To +no' t)! "#&!. t)! -#"ro? #nd t)! -i"ro"o(i"#% ")#r#"t!riti". %o"#%i#tion #nd

o&t"o-! o$ t)! )y#%in!?dro(%!t. )ydro(i" #nd # +!r#tini#tion dytro()i#

@ To +no' t)! "#&! o$ # $#tty dytro()i#. (ri-#ry %o"#%i#tion. t)! -#"ro? #nd t)!

-i"ro"o(i"#% ")#r#"t!riti" o$ ")#n,! in # -yo"#rdi&-. %i*!r #nd +idn!y

To +no' #bo&t )ito")!-i"#% -!t)od o$ r!*!#%in, o$ %i(id in ti&!

To )#*! t)! b#i" "on"!(t #bo&t t)! "#rbo)ydr#t! -!t#bo%i- in #n or,#ni- #nd)ito")!-i"#% -!t)od o$ t)!ir r!*!#%in, in ti&!

40 To +no' t)! "#&!. t)! "%ini"#% #nd -or()o%o,i"#% -#ni$!t#tion o$ # di#b!t!

"onn!"t!d 'it) dit&rb#n"! o$ ,%y"o,!n -!t#bo%i-

44 To +no' !5#-(%! o$ t)! di!#! =oin 'it) dit&rb#n"! o$ ,%y"o(rot!in -!t#bo%i-

LABORATORY WORK № "

GROSS SPECIMENS:

4 F#tty dytro()i# o$ -yo"#rdi&- ti,!r )!#rt

D!"ri(tion3 !! b#i" -#t!ri#%

2 F#tty dytro()i# o$ # %i*!r ,oo! %i*!r

D!"ri(tion3 %i*!r !n%#r,!d in i!. $%#bby. on # "&t &r$#"! )# y!%%o' "o%o&rin, 'it) # ,r!#y

#((!#r#n"!

9 Hy(!r+!r#toi o$ # +in d!r-#% )orn

MICROSLIDES:

4? Gy#%in!?dro(%!t dytro()i# o$ !(it)!%i&- o$ t)! "on*o%&t!d t&b&%! in +idn!y D!-ontr#tion

20;? Hydro(i" dytro()i# o$ # -yo"#rdi&- D!-ontr#tion

49? B#%%oonin, dytro()i# o$ )!(#to"yt! To dr#'

2;? F#tty dytro()i# o$ )!(#to"yt!? To dr#'

? D!(oition o$ # ,%y"o,!n in t)! !(it)!%i&- o$ H!n%!7 %oo( o$ +idn!y in di#b!t!

D!-ontr#tion

№ 1#$ HYDROPIC AND BALLOONING DYSTROPHIA OF HEPATOCYTES IN

VIRUS HEPATITIS In t)! -i"ro%id! &nd!r -#%% -#,ni$i"#tion yo& "#n !! ti&! o$ # %i*!r 'it) t)! -#r+!d %ob!d

"ontit&tion. "#&!d by in$%#--#tory in$i%tr#tion o$ #n int!r%ob&%#r "onn!"tin, ti&! T)! -ot o$

)!(#ti" %ob&%! #r! (#%! (#int!d b!"#&! o$ (r!!n"! in "yto(%#- o$ )!(#to"yt! t)! -#%% #nd

%#r,!r *#"&o%! ')i") #r! (&)in, #id! n&"%!& o$ "!%% to (!ri()!ry &it! o$t!n #-on, &") "!%%

t)!r! #r! )#r(%y !n%#r,!d )!(#to"yt!. o*!rb%o'n # "y%ind!r #nd 'it)o&t n&"%!&? it i

b#%%oonin, dytro()i#

D!i,n#tion3

4? Hydro(i" /*#"&o%#r dytro()i# o$ )!(#to"yt!

2? B#%%oonin, dytro()i# o$ )!(#to"yt!

9? In$%#--#tory in$i%tr#tion o$ t)! int!r%ob&%#r "onn!"ti*! ti&!

№ "% FATTY DYSTROPHIA OF THE LIVER F#t t#in 'it) &d#n in or#n,! "o%o&r #nd $i%% t)! "yto(%#- o$ )!(#to"yt!. -#in%y # on! bi,

dro( T)! )!(#to"yt! ')i") #r! %o#d!d 'it) $#t )# ()!ri"#% $or- F#tty dytro()i# in*o%*! bot)



t)! "!ntr#% #nd (!ri()!r#% tr&"t&r! o$ )!(#ti" %ob&%!

D!i,n#tion3

4? "!ntr#% *!in

2? )!(#ti" "!%% %o#d!d 'it) $#t

9? nor-#% )!(#to"yt!

№ 1#$ HYDROPIC AND BALLOONING DYSTROPHIA OF HEPATOCYTES IN

VIRUS HEPATITISt#inin,3 )!-#to5y%in? !oin

M#,ni$i"#tion3

D!i,n#tion3

4? Hydro(i" /*#"&o%#r dytro()i# o$ )!(#to"yt!

2? B#%%oonin, dytro()i# o$ )!(#to"yt!

9? In$%#--#tory in$i%tr#tion o$ t)! int!r%ob&%#r "onn!"ti*! ti&!

№ "% FATTY DYSTROPHIA OF THE LIVER

t#inin,3 &d#n 9. &d#n :

M#,ni$i"#tion3

D!i,n#tion3

4? C!ntr#% *!in

2? H!(#ti" "!%% %o#d!d 'it) $#t

9? Nor-#% )!(#to"yt!

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME:

STROMAL-VASCULAR DYSTROPHIAS

THE BASIC QUESTIONS OF THE THEME.

4 To +no' #bo&t tr&"t&r! o$ "onn!"tin, ti&! #nd )ito")!-i"#% -!t)od o$ t#inin, o$ it

$ib!r

2 To +no' d!$inition #nd "%#i$i"#tion o$ tro-#%?*#"&%#r dytro()i#9 To +no' t)! "#&!. %o"#%i#tion. -or()o%o,y #nd o&t"o-! o$ t)! -&"oid #nd $ibrinoid

'!%%in,



: To +no' #bo&t tr&"t&r#% "o-(on!nt o$ )y#%in

; To +no' t)! "#&! #nd "%#i$i"#tion o$ )y#%inoi. to +no' di!#! #nd (#t)o%o,i"#%

(ro"!! in ')i") %o"#% #nd yt!-i" )y#%inoi #r! r!*!#%!d

6 To +no' d!$inition o$ "on"!(t >#-y%oidoi> #nd to )#*! "on"!(tion #bo&t ()yi"#% #nd

")!-i"#% (ro(!rti! o$ t)! #-y%oidoi

@ To +no' "%#i$i"#tion o$ #n #-y%oidoi8 to b! #b%! to n#-! -#"ro"o(i"#% #nd

)ito")!-i"#% -!t)od r!*!#%in, o$ #-y%oid To +no' -#"ro"o(i"#% #nd -i"ro"o(i"#% ")#r#"t!riti" o$ t)! #-y%oidoi in di$$!r!nt

or,#n

To +no' t)! "#&! o$ d!*!%o(-!nt #nd "%#i$i"#tion o$ t)! ,!n!r#% ob!ity. -#"ro? #nd

-i"ro"o(i"#% ")#r#"t!riti" o$ )!#rt in ob!ity

40 To b! #b%! to n#-! #n #nti(od! o$ t)! ,!n!r#% ob!ity. #nd #%o to +no' #bo&t

%y(o-#to!!

LABORATORY WORK № #

GROSS SPECIMENS:

4 Hy#%inoi o$ t)! (%!!n "#(&%!

D!"ri(tion3 t)! "#(&%! o$ (%!!n i irr!,&%#r%y t)i"+!n!d. d!n!. ')it! "o%o&r. ,%oy.

!-itr#n(#r!nt. r!-ind #((!#r#n"! o$ ,%#! $or "o*!rin, "#+!2 Art)!rio"%!roti" n!()ro"yrroi /(ri-#ry "ontr#"t!d +idn!y

D!"ri(tion3 (ri-#ri%y "ontr#"t!d +idn!y /#t idio(#t)i" )y(!rt!ni#3 i! o$ +idn!y "onid!r#b%y

r!d&"!d. "onit!n"! i d!n!. #nd &r$#"! i ,r#in!d d&! to $or-#tion o$ r!tr#"tion in (%#"! ')!r!

non$&n"tionin, n!()ron r!(%#"!d 'it) "#r Protr&ion o$ on &r$#"! o$ +idn!y #r! "#&!d by t)!

,%o-&%&!. ')i") #$$!r!nt #rt!rio%! #r! #*!d T)!r! i &ni$or- t)inin, o$ t)! r!n#% "ort!5

/,r#yi) "o%o&r!d on t)! !"tion F&n"tion o$ +idn!y i )#r(%y r!d&"!d. #nd (#ti!nt (!ri) $ro-

r!n#% $#i%&r!

9 A-y%oidoi o$ # (%!!n /#,o (%!!n

D!"ri(tion3 (%!!n i !n%#r,!d in i!. it "onit!n"! i d!n!. #nd on # !"tion t)!r! #r! *iib%!

!-i?tr#n(#r!nt ,r#in o$ t)! ()!ri"#% $or- 'it) ,r!#y ,%o. r!-indin, "oo+!d #,o &")

(%!!n 'it) $o"#% d!(oition o$ #n #-y%oid in !%!-!nt o$ # ')it! (&%( r!"!i*!d t)! n#-! #,o?

(%!!n

: A-y%oidoi o$ # +idn!y /bi, %#rd#"!o& +idn!y

D!"ri(tion3 +idn!y !n%#r,!d in i!. it "onit!n"! i d!n! On # !"tion "ort!5 o$ +idn!y i

)#r(%y t)i"+!n!d 'it) ")#r#"t!riti" ,r!#y ,%o &") +idn!y )#*! b!!n n#-!d bi, %#rd#"!o&

+idn!y

; Ob!ity o$ )!#rt

D!"ri(tion3 )!#rt !n%#r,!d in i!. d!(oition o$ $#t #r! *iib%! &nd!r #n !(i"#rdi&- T)! $#tty

ti&! $ro- #n !(i"#rdi&- (!n!tr#t! b!t'!!n -&"%! $ib!r o$ -yo"#rdi&- into it tro-# M&"%!

$ib!r #r! t)inn!d #nd #tro()i" C%ini"#% y-(to- o$ )!#rt ob!ity i d!"r!#in, o$ "ontr#"ti%ity o$

-yo"#rdi&- o-!ti-! (#ti!nt (!ri) b!"#&! o$ %#"!r#tion o$ #di(o!d ri,)t *!ntri"%! o$ )!#rtMICROSLIDES:

22? Hy#%inoi o$ t)! "!ntr#% #rt!rio%! o$ (%!!n $o%%i"%! To dr#'

4? A-y%oidoi o$ t)! %i*!r /%#rd#"!o& %i*!r To dr#'

@6? Ob!ity o$ )!#rt /$#tty )!#rt To dr#'

N "" HYALINOSIS OF THE CENTRAL ARTERIOLES OF FOLLICLES OF THE SPLEEN

In # -i"ro%id! o$ # (%!!n it i n!"!#ry to $ind t)! "!ntr#% #rt!rio%! o$ $o%%i"%! A '#%% o$

#rt!rio%! )#r(%y t)i"+!n!d. )o-o,!ni!d. &ntr&"t&r!d L&-!n o$ #rt!rio%! #r! n#rro'!d

D!i,n#tion3

4? Fo%%i"%! o$ # (%!!n

2? C!ntr#% #rt!rio%! 'it) )y#%ini!d '#%% #nd t)! n#rro'!d %&-!n

№ 1& AMYLOIDOSES OF THE LIVER



T)! tr&"t&r! o$ t)! %i*!r i d#-#,! b!"#&! o$ #-y%oid #""&-&%#tion It i n!"!#ry to $ind

it! 'it) t)! ,r!#t!t "ont!nt o$ #-y%oid #nd to "o-(#r! t)!- 'it) (%#"! ')!r! #-y%oid it i

$o&nd o&t in r#t)!r ini,ni$i"#nt 1&#ntity It #((!#r. t)#t #""&-&%#tion o$ #-y%oid #r! in t)! b!t

'#y !5(r!!d in (!ri()!r#% d!(#rt-!nt o$ %ob&%!. in t)! "!nt!r %ob&%! #-y%oid it i not

!no&,) In t)! "!nt!r o$ %ob&%! )!(#ti" br#n")! )#*! nor-#% t)i"+n!. on (!ri()!ry t)!y #r!

)#r(%y n#rro'!d. 1&!!!d by #-y%oid. ')i") #r! d!(oit &nd!r !ndot)!%i&- o$ "#(i%%#ri! At t)!

i,ni$i"#nt #""&-&%#tion o$ #-y%oid )!(#ti" br#n")! #r! not $o&nd o&t #t #%%D!i,n#tion3

4? A""&-&%#tion o$ #-y%oid in (!ri()!r#% d!(#rt-!nt o$ %ob&%!

2? N#rro'!d. 1&!!!d by #-y%oid )!(#ti" br#n")!

9? U&#% t)i"+n! )!(#ti" br#n")! in t)! "!ntr#% d!(#rt-!nt o$ %ob&%!

N '( OBESITY OF HEART

T)! &b"#rdi#% $#tty tr#t&- )#r(%y t)i"+!n!d F#t in # (%!nty i #""&-&%#t!d in # tro-# o$ #

-yo"#rdi&-. -o*in, #(#rt -&"&%#r $ib!r. #nd t)!y b!"#-! #tro()i"

D!i,n#tion3

4? &b!(i"#rdi#% tr#t&-

2? D!(oit o$ # $#t in int!r-&"&%#r "onn!"tin, ti&!

9? T)innin, o$ -&"&%#r $ib!rN "" HYALINOSIS OF THE CENTRAL ARTERIOLES OF FOLLICLES OF THE SPLEEN

t#inin,3 )!-#to5y%in? !oin

-#,ni$i"#tion3

D!i,n#tion3

4? Fo%%i"%! o$ # (%!!n

2? C!ntr#% #rt!rio%! 'it) )y#%ini!d '#%% #nd t)! n#rro'!d %&-!n

№ 1& AMYLOIDOSES OF THE LIVER

t#inin,3 Con,o r!d

-#,ni$i"#tion3

D!i,n#tion3

4? A""&-&%#tion o$ #-y%oid in (!ri()!r#% d!(#rt-!nt o$ %ob&%!

2? N#rro'!d. 1&!!!d by #-y%oid )!(#ti" br#n")!

9? U&#% t)i"+n! )!(#ti" br#n")! in t)! "!ntr#% d!(#rt-!nt o$ %ob&%!N '( OBESITY OF HEART )*+ /+0

t#inin,3 )!-#to5y%in?!oin



-#,ni$i"#tion3

D!i,n#tion3

4? &b!(i"#rdi#% tr#t&-

2? D!(oit o$ # $#t in int!r-&"&%#r "onn!"tin, ti&!

9? T)innin, o$ -&"&%#r $ib!r

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: MI2ED DYSTROPHIAS. THEBASIC QUESTIONS OF THE THEME:

4 To +no' #bo&t %o"#%i#tion o$ %!ion in -i5!d dytro()i# #nd (rin"i(%! o$ t)!ir

"%#i$i"#tion

2 To b! #b%! to ,i*! # ,!n!r#% ")#r#"t!riti" to dit&rb#n"! o$ t)! ")ro-o(rot!in -!t#bo%i-

9 To +no' o&r"! o$ d!*!%o(-!nt. # (#t)o,!ny #nd -or()o%o,i"#% -#ni$!t#tion o$ t)!

)#!-o,%obin! (i,-!nt. to b! #b%! to %it $!rri$!ro& (i,-!nt #nd not "ont#inin, iron

(i,-!nt

: To )#*! r!(r!!nt#tion #bo&t t)! b#i" -#ni$!t#tion o$ dit&rb#n"! o$ #n !5")#n,! o$ #

)!-oid!rin

; To +no' #bo&t t)! b#i" -#ni$!t#tion o$ dit&rb#n"! o$ t)! bi%ir&bin -!t#bo%i-

6 To b! #b%! to d!$in! "on"!(t >=#&ndi"!> #nd to +no' it ty(!

@ To +no' #n !tio%o,y. (#t)o,!ny #nd -or()o%o,y. #nd #%o t)! b#i" "%ini"#% -#ni$!t#tion

&(r#)!(#ti" /)!-o%yti" =#&ndi"!. b # )!(#ti" /(#r!n")y-#to& =#&ndi"!. "&b)!(#ti"

/-!")#ni"#% =#&ndi"!

To +no' #bo&t t)! b#i" -#ni$!t#tion o$ dit&rb#n"! o$ t)! )!-#tin -!t#bo%i-

To +no' n#t&r!. o&r"! o$ d!*!%o(-!nt #nd "%ini"o?-or()o%o,i"#% -#ni$!t#tion o$

dit&rb#n"! o$ t)! -!t#bo%i- o$ (rot!ino,!no& (i,-!nt#tion

40 To b! #b%! to %it %i(ido,!no& (i,-!nt #nd to ,i*! ")#r#"t!riti" o$ t)! dit&rb#n"! o$

t)!ir -!t#bo%i-

44 To +no' # ,!n!r#% ")#r#"t!riti" #nd (rin"i(%! o$ "%#i$i"#tion o$ t)! -in!r#% dytro()i#

42 To +no' "%!#r%y t)! b#i" -#ni$!t#tion o$ dit&rb#n"! o$ t)! "#%"i&- -!t#bo%i- inor,#ni-

49 To +no' "%!#r%y *#ri!ti! o$ t)! "#%"i$i"#tion #nd to ,i*! t)!- "%ini"#%?#n#to-i"#%

")#r#"t!riti". $ro- t)! (oint o$ *i!' o$ t)! -or(),!n!i


GROSS SPECIMENS:

4? Bro'n #tro()i# o$ t)! %i*!r

2? Bro'n ind&r#tion o$ t)! %&n, /)!-oid!roi o$ t)! %&n,

9? Mor()o%o,y o$ ton! /#((!#r#n"! #nd "ontit&tion

:? #%"&%o& ")o%!"ytiti/,#%%ton!

;? M!%#no-# /# -!%#nob%#to-# ? -!t#t#i in # %i*!r

MICROSLIDES:9:?#? Bro'n #tro()i# o$ t)! %i*!r To dr#'

90? H!-oid!roi o$ # %i*!r To dr#'



:? Dytro()i" "#%"i$i"#tion o$ # -yo"#rdi&- To dr#'

N #4 HEMOSIDEROSIS OF THE LIVER.

In "yto(%#- o$ )!(#ti" "!%% t)! "%&-( o$ #b&nd#nt 1&#ntity o$ t)! $!rri$!ro& (i,-!nt

t#in!d on P!r% -!t)od in ,r!!n?d#r+ b%&! "o%or i -#r+!d /"o%or o$ t)! Pr&i#n b%&! N&"%!i

o$ t)! %i*!r "!%% #r! t#in!d in "#r-in!?r!d "o%or

D!i,n#tion3

4 T)! )!(#ti" "!%% %o#d!d by ,r#in o$ t)! ,!-oid!rin. t#in!d in ,r!!n?d#r+ b%&! "o%or N $3 DYSTROPHIC CALCIFICATION OF THE MYOCARDIUM

In *#rio& $i!%d o$ *iion in # %id! t)! di$$&!d %o"&! o$ # -yo"#rdi&- o$ # di$$!r!nt i!

#nd $or-. t#in!d in d#r+?*io%!t "o%o&r #r! *iib%! T)!! $o"&! r!(r!!nt b&n")! o$ t)!

-&"&%#r $ib!r. &nd!r,on! to # d!!( (#r!n")y-#to& dytro()i#. n!"robioi #nd n!"roi

'it) t)! &b!1&!nt i-(r!,n#tion o$ t)!- by #%t o$ # %i-! Aro&nd o$ t)! $o"&! o$ #

"#%"i$i"#tion. #nd #%o #-on, n!"roti!d $ib!r #b&nd#nt %!&"o"yt!?%y-()oid in$i%tr#tion #

r!&%t o$ # r!#"ti*! in$%#--#tion

D!i,n#tion3

4? C#%"i$i!d $i!%d o$ # -yo"#rdi&-

2? In$%#--#tory (!ri$o"#% r!#"tion

№ #3-+ BRAWN ATROPHIA OF A LIVER.

H!(#ti" "!%% #r! r!d&"!d in i! T)! "!ntr#% *!in #nd "#(i%%#ri! in t)! "!nt!r %ob&%! #r!

!5(#nd!d. )!(#ti" br#n")! #r! n#rro'!d. in "yto(%#- o$ "!%% in t)! "!ntr#% (#rt o$ %ob&%! #r!

*iib%! t)! d!(oition o$ y!%%o' ? bro'n (i,-!nt %i(o$&"in

D!i,n#tion3

4? Li(o$&"in d!(oition

2? T)! "!ntr#% *!in #nd "#(i%%#ri! in t)! "!nt!r %ob&%!

N #4 HEMOSIDEROSIS OF THE LIVER.

t#inin,3 Pr&i#n b%&! /on P!r% -!t)od

-#,ni$i"#tion3

D!i,n#tion3

4 T)! )!(#ti" "!%% %o#d!d by ,r#in o$ t)! ,!-oid!rin. t#in!d in ,r!!n?d#r+ b%&! "o%or

N $3 DYSTROPHIC CALCIFICATION OF THE MYOCARDIUM




-#,ni$i"#tion3

D!i,n#tion3

4? "#%"i$i!d $i!%d o$ # -yo"#rdi&-

2? in$%#--#tory (!ri$o"#% r!#"tion

№ #3-+ BRAWN ATROPHIA OF A LIVER.


-#,ni$i"#tion3

D!i,n#tion3

4? Li(o$&"in d!(oition

2? T)! "!ntr#% *!in #nd "#(i%%#ri! in t)! "!nt!r %ob&%!

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: NECROSIS. APOPTOSIS.

GENERAL DEATH.


4 To +no' d!$inition o$ "on"!(t3 >NECROI>

2 To )#*! t)! ,!n!r#% r!(r!!nt#tion #bo&t # n!"robioi. (#r#n!"roi9 To +no' "%!#r%y -i"ro"o(i"#% $!#t&r! o$ n!"roi3 J)#n,! o$ n&"%!&. b ")#n,! o$

"yto(%#-. J J)#n,! o$ int!r"!%%&%#r -#t!ri#%

: To +no' -#"ro"o(i"#% $!#t&r! o$ t)! n!"roi

; To +no' $!#t&r! o$ # n!"roi o$ $#tty ti&!

6 To +no' "%!#r%y "%#i$i"#tion o$ # n!"roi3 A""ordin, to -!")#ni- o$ d!*!%o(-!nt.

b A""ordin, to #!tio%o,y

@ To +no' "%!#r%y "%ini"#%?#n#to-i"#% $or- o$ # n!"roi T)! -#"ro?-i"ro"o(i"#%

")#r#"t!riti" o$ "o#,&%#ti*! n!"roi. it !5#-(%!. b T)! -#"ro?-i"ro"o(i"#%

")#r#"t!riti" o$ "o%%i1&#ti*! K%i1&!$#"ti*! n!"roi. " +ind #nd ty(! o$ # ,#n,r!n!. d

to b! #b%! to d!$in! "on"!(t >!1&!t!r. ! to +no' d!$inition o$ in$#r"t

To +no' #bo&t $!#t&r! o$ # n!"roi in $!t#% #,! #nd ")i%dr!n7 #,! To +no' o&t"o-! o$ # n!"roi /$#*or#b%!. &n$#*or#b%! To )#*! "on"!(t #bo&t # %in!

o$ d!-#r"#tion



40 V#%&! o$ # n!"roi $or or,#ni-

44 To )#*! "on"!(t #bo&t d!#t). to +no' "%#i$i"#tion o$ d!#t) #""ordin, to "#&#ti*!

$#"tor

42 To +no' n#t&r! o$ "on"!(t3 #((#r!nt d!#t). bio%o,i"#% d!#t)

49 To +no' $!#t&r! o$ d!#t) #nd (ot-ort!- ")#n,!

4: A(o(toi M!")#ni- o$ #(o(toi Ditin,&i)in, $!#t&r! 'it) n!"roi V#%&! o$

#(o(toiLABORATORY WORK № %

GROSS SPECIMENS:

4? G#n,r!n! o$ $oot

D!"ri(tion3 t)! d!#d ti&! i b%#"+. dry. #nd )ri*!%!d T)! n!"rotiin, ti&! i b%#"+ d&! to t)!

&%()&ro& iron t)#t $or-!d $ro- (i,-!nt o$ b%ood /)!-o,%obin &nd!r t)! #"tion o$ #ir #nd

d!"#yin, &%$&ry #-ino #"id o$ (rot!in T)! d!#d ti&! i )#r(%y d!-#r"#t!d $ro- #d=#"!nt

*i#b%! ti&!

2? I")!-i" in$#r"t o$ # (%!!n

D!"ri(tion3 in (%!!n ti&! t)!r! i on! '!d,!?)#(!d in$#r"t T)!ir "onit!n"! i d!n! T)!

b#! o$ t)! in$#r"t #r! in*!rt!d to # "#(&%!. in$#r"t!d #r!# o*!r)#n, $ro- &nd!r "#(&%! A

"#(&%! &r$#"! i ro&,) in t)! in$#r"t!d #r!# o'in, to (r!!n"! o$ $ibrino& !5&d#t!9? Gr!y !n"!()#%o-#%#"i# o$ # br#in

:? #!o& K"#!#tion n!"roi o$ %y-()onod&!

D!"ri(tion3 ro&ndi) "!nt!r #r! *iib%! in t)! ti&! o$ %y-() nod! T)!y #r! ')it!?,r#y "o%or!d.

$ri#b%!8 r!-indin, #((!#r#n"! o$ "ott#,! ")!!! &") "!nt!r #r! $or-in, o'in, to "ond!n#tion o$

t)! n!"roti" -#! &it! o$t!n t)!y #r! !n"#(&%#tin, #nd #r! !5(o!d to d!(oit o$ "#%"i&-

/(!tri$#"tion8 bon! ti&! "#n b! $or-!d in &") "!nt!r /oi$i"#tion

MICROSLIDES:

;? In"#(&%#t!d "#%"i$i!d $o"& o$ "#!o& K"#!#tion n!"roi in # %y-()onod& To dr#'

9;? Co#,&%#tion n!"roi o$ !(it)!%i&- dit#% "on*o%&t!d r!n#% t&b&%! To dr#'

:? I")!-i" in$#r"t o$ (%!!n To dr#'

№ % INCAPSULATED CALCIFIED FOCUS OF CASEOUS 5CASEATION6 NECROSIS

IN A LYMPHONODUS.

In t)! ti&! yo& "#n $ind t)! $o"&! o$ "#!o& K"#!#tion n!"roi. ')i") #r! "ir"%!d by

"onn!"ti*! ti&! -!-br#n! T)! "!ntr#% (#rt o$ t)!! $o"&! #r! t#n!d in *io%!t "o%o&r. d&!

to t)! dro((!d o&t #%t o$ %i-!

D!i,n#tion3

4? T)! $o"&! o$ "#!o& K"#!#tion n!"roi

2? Fo"& o$ "#%"i$i"#tion

9? Conn!"ti*! ti&! -!-br#n!

№ 3 ICHEMIC INFARCT OF SPLEEN.

In t)! %id! yo& "#n $ind t)r!! on!3 t)! $irt on! i &b-itt!d by # $i!%d o$ &ntr&"t&r!d

-#. '!#+%y t#in!d by #"idi" (#int T)! ori,in#% tr&"t&r! o$ (%!!n i (r!!nt on%y # # (#%!

t#in!d tr#b!"&%! T)! $i!%d o$ in$#r"t. ')i") i %o"#t!d &nd!r t)! (%!n!ti" "#(&%!. i

&rro&nd!d by 'id! on! o$ d!troy!d %!&"o"yt!T)! !"ond on! i # )#!-orr)#,i" on! 'it)

$!#t&r! o$ b!,innin, or,#ni#tion /"%!roi o$ $i!%d o$ # )!-orr)#,! T)!n t)!r! i t)! t)ird

on!? ti&! o$ t)! (%!!n in # t#t! o$ t)! !5(r!!d !d!-#

D!i,n#tion3

4? Fi!%d o$ #n in$#r"t3 n&"%!#r d!triti. b (#%! t#in!d tr#b!"&%!. " on! o$ d!troy!d %!&"o"yt!

2? T)! )#!-orr)#,i" on!

9? Ti&! o$ # (%!!n№ #% COAGULATION NECROSIS OF THE EPITHELIUM OF DISTAL

CONVOLUTED RENAL TUBULE.



G%o-&%&! #r! not ")#n,!d Con*o%&t!d r!n#% t&b&%! #r! (#%! t#in!d. t)! !(it)!%i#% "!%% #r!

'o%%!n. 'it)o&t t)! n&"%!i. t)! &r*i*in, n&"%!i #r! t#in!d '!#+%y In H!n%!7 %oo( #nd in tr#i,)t

t&b&%! t)! n&"%!i &r*i*in, #nd '!%% t#in!d by # )!-#to5y%in

D!i,n#tion3

4? G%o-&%& 'it) t)! &r*i*in, n&"%!i

2? Con*o%&t!d r!n#% t&b&%! 'it)o&t t)! n&"%!i

9? tr#i,)t t&b&%! 'it) t)! &r*i*in, n&"%!i

№ % INCAPSULATED CALCIFIED FOCUS OF CASEOUS NECROSIS IN

LYMPHONODUS.

t#inin,3 # )!-#to5y%in !oin

-#,ni$i"#tion3

D!i,n#tion3

4? T)! $o"&! o$ "#!o& n!"roi

2? Fo"& o$ "#%"i$i"#tion

9? Conn!"ti*! ti&! -!-br#n!

№ 3 ANEMIC INFARCT OF SPLEEN.


-#,ni$i"#tion3

D!i,n#tion3

4? Fi!%d o$ #n in$#r"t3 n&"%!#r d!triti. b (#%! t#in!d tr#b!"&%!. " on! o$ d!troy!d %!&"o"yt!

2? H#!-orr)#,i" on!

9? Ti&! o$ # (%!!n

№ #% COAGULATION NECROSIS OF THE EPITHELIUM OF DISTAL

CONVOLUTED RENAL TUBULE.




-#,ni$i"#tion3

D!i,n#tion3

4? G%o-&%& 'it) t)! &r*i*in, n&"%!i

2? Con*o%&t!d r!n#% t&b&%! 'it)o&t t)! n&"%!i

9? tr#i,)t t&b&%! 'it) t)! &r*i*in, n&"%!i

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME:

HEMODINAMIC DISORDERS )HYPEREMIA, CONGESTION, BLEEDING, EDEMA.


4 To +no' "%#i$i"#tion o$ dit&rb#n! o$ t)! %y-()o?#nd b%ood "ir"&%#tion

2 To ,i*! t)! d!$inition o$ #rt!ri#% )y(!r!-i# To +no' it ty(! in d!(!nd!n"! on (r!*#%!n"!

o$ (ro"! #nd it "#&!

9 To ,i*! t)! d!$inition o$ *!no& "on,!tion To +no' it "#&! #nd t)! b#i" -or()o%o,i"#%

")#n,! in or,#n #nd ti&! in #"&t! #nd ")roni" *!no& "on,!tion

: To +no' #bo&t $!#t&r! o$ ")#n,! in # +in. +idn!y. (%!!n. #t t)! yt!-i" *!no&

"on,!tion

; To +no' "%!#r%y # -or(),!n!i o$ ")#n,! in t)! %i*!r #nd %&n, in ")roni" *!no&

"on,!tion. ,ro #nd t)! -i"ro"o(i" ")#r#"t!riti" o$ # n&t-!, %i*!r #nd # bro'n

ind&r#tion o$ t)! %&n,

6 To +no' #bo&t t)! "#&!. -or()o%o,i"#% $!#t&r! #nd o&t"o-! o$ %o"#% *!no& "on,!tion

in # %i*!r. +idn!y. !5tr!-iti! #nd int!tin!

@ To ,i*! t)! d!$inition o$ i")!-i# To +no' it "#&!. *#%&! #nd "on!1&!n"!

To +no' "%#i$i"#tion o$ i")!-i# in d!(!nd!n"! on t)! "#&! #nd "ondition o$

ori,in#tin, To b! #b%! to ,i*! bri!$ d!"ri(tion o$ it ty(!

To ,i*! t)! d!$inition o$ b%!!din,. )!-orr)#,!. )#!-#to-#. )!-orr)#,i" (!r-!#tin,.

!"")y-oi40 To +no' #bo&t t)! b#i" +ind int!rn#% #nd !5t!rn#% b%!!din,. #nd #%o &!d in t)!! "#! o$

t!r-ino%o,y

44 To +no' (rin"i(#% "#&! o$ # b%!!din, #nd to b! #b%! to ,i*! t)!- t)! bri!$ ")#r#"t!riti"

42 To ,i*! t)! d!$inition o$ (%#-orr)#,i# To +no' t)! -!")#ni- o$ it d!*!%o(-!nt.

-i"ro"o(i" $!#t&r! #nd o&t"o-!

49 To +no' #bo&t t)! $#"tor r!,&%#tin, "ont!nt o$ int!r"!%%&%#r %y-() To +no' t)!

")#r#"t!riti" o$ tr#n&d#t! #nd t)! t!r-. ')i") #r! &!d $or not#tion o$ #""&-&%#tion

)ydro(i" $%&id in ti&! #nd "#*iti! o$ t)! or,#ni-

4: To +no' ty(! o$ !d!-# #nd t)! -!")#ni- o$ d!*!%o(-!nt o$ it *#rio& +ind

4; To +no' #bo&t !5i"oi To +no' it "#&! #nd t)! -or()o%o,i"#% ")#n,! #riin, in

or,#n #nd ti&!LABORATORY WORK № (

GROSS SPECIMENS:



4? N&t-!, %i*!r

2? Bro'n ind&r#tion o$ t)! %&n,

9? H!-orr)#,! in # br#in in idio(#t)i" )y(!rt!ni#

:? Myo"#rdi#% in$#r"tion 'it) # r&(t&r! #nd "#rdi#" t#-(on#d!

MICROSLIDES3

4? N&t-!, %i*!r To dr#'2? Bro'n ind&r#tion o$ t)! %&n, To dr#'

? Di#(!d!ti" )!-orr)#,! in # -#in br#in To dr#'

40@? Ed!-# o$ %&n,/ D!-ontr#tion

№ 1. NUTMEG LIVER

T)! %ob!d "ontit&tion o$ # %i*!r i not ")#n,!d At %o' -#,ni$i"#tion "!ntr#% *!in #nd t)!

"#(i%%#r o$ t)! "!ntr#% (#rt o$ %ob&%! #r! )#r(%y di%#t!d #nd o*!r$%o'n 'it) # b%ood C#(i%%#r o$ #

(!ri()!ri" (#rt o$ t)! %ob&%! )#*! nor-#% di#-!t!r H!(#ti" "!%% in t)! "!ntr#% (#rt o$ %ob&%!

)#r(%y r!d&"!d in i! or #r! "o-(%!t!%y not *iib%!. on (!ri()!ry )!(#ti" "!%% )#*! nor-#% i!

D!i,n#tion3

4? T)! "!ntr#% *!in )#r(%y di%#t!d #nd o*!r$%o'n 'it) # b%ood2? T)! "#(i%%#r o$ t)! "!ntr#% (#rt o$ %ob&%! di%#t!d #nd o*!r$%o'n 'it) # b%ood

9? Atro()y o$ )!(#ti" br#n")! in t)! "!nt!r o$ %ob&%!

:? Not ")#n,!d )!(#ti" br#n")! on (!ri()!ry o$ %ob&%!

№ ". BROWN INDURATION OF THE LUNGS.

T)! #%*!o%#r tr&"t&r! o$ t)! %&n, i not ")#n,!d Vi!nn# #nd "#(i%%#r #r! di%#t!d #nd o*!r$%o'n

Int!r#%*!o%#r !(t&- #nd (!ri*#"&%#r %#y!r #r! t)i"+!nin, d&! to (%!t)or#. #n !d!-# #nd ,ro't)

o$ # "onn!"ti*! ti&! T)! %&-!n o$ #%*!o%&! i $r!!. b&t in o-! (%#"! i !5!"&t!d by

(rot!in#"!o& )ydro(i" $%&id. !ryt)ro"yt! #nd -#"ro()#,! 'it) # )!-oid!rin? )!#rt di!#!

"!%% In t)! "!ntr#% ti&! #ro&nd o$ bron")&! #nd *!!% t)!r! #r! d!(oit o$ "o#%

D!i,n#tion3

4? Vi!nn# #nd "#(i%%#r #r! di%#t!d #nd o*!r$%o'n

2? T)i"+!nin, #%*!o%#r !(t&-

9? Hydro(i" (rot!in#"!o& $%&id

:? Eryt)ro"yt!

;? )!#rt di!#! "!%%

№ &. DIAPEDETIC HEMORRHAGES IN A BRAIN

In ')it! &bt#n"! o$ # br#in yo& "#n !! -#%% #nd %#r,!r )!-orr)#,! ')i") #r! it&#t!d

-#in%y #ro&nd o$ di%#t!d #nd )#r(%y (%!t)ori" *!!% #%% o$ *!!% #r! indi"!rnib%! o'in, to

#b&nd#nt i-(r!,n#tion by t)!ir !ryt)ro"yt! In o-! (%#"! it i (oib%! to !! # bro'n (i,-!nto$ t)! )!-oid!rin. r!or(tion o$ it t!ti$yin, to t)! b!,innin, o$ r!or(tion b%oody -#! ')i")

#r! t)! $%o' o&t b!$or!

D!i,n#tion3

4? T)! %o"&! o$ )!-orr)#,! in ')it! &bt#n"! o$ # br#in

2? P%!t)ori" *!!% 'it) i-(r!,n#tion o$ '#%% by !ryt)ro"yt!

№ 1. NUTMEG LIVER




-#,ni$i"#tion3

D!i,n#tion3

4? T)! "!ntr#% *!in )#r(%y di%#t!d #nd o*!r$%o'n 'it) # b%ood

2? T)! "#(i%%#r o$ t)! "!ntr#% (#rt o$ %ob&%! di%#t!d #nd o*!r$%o'n 'it) # b%ood

9? Atro()y o$ )!(#ti" br#n")! in t)! "!nt!r o$ %ob&%!

:? Not ")#n,!d )!(#ti" br#n")! on (!ri()!ry o$ %ob&%!

№ ". BROWN INDURATION OF THE LUNGS.


-#,ni$i"#tion

4? Vi!nn# #nd "#(i%%#r #r! di%#t!d #nd o*!r$%o'n

2? T)i"+!nin, #%*!o%#r !(t&-

9? Hydro(i" (rot!in#"!o& $%&id

:? Eryt)ro"yt!

;? )!#rt di!#! "!%%

№ &. DIAPEDETIC HEMORRHAGES IN A BRAIN


-#,ni$i"#tion

D!i,n#tion3

4? T)! %o"&! o$ )!-orr)#,! in ')it! &bt#n"! o$ # br#in

2? P%!t)ori" *!!% 'it) i-(r!,n#tion o$ '#%% by !ryt)ro"yt!

i,n#t&r! o$ t!#")!r3 D#t!3



EDUCATIONAL-TARGET QUESTIONS ON THE THEME: DISTURBANSES OF THE

LYMPHO-AND BLOOD CIRCULATIONS )THROMBOSIS, EMBOLISM, INFARCT,

SHOCK, DIC


4 To +no' d!$inition o$ t)ro-boi

2 To +no' #bo&t t)! ")!-# o$ b%ood "o#,&%#tion #nd #bo&t t)! -!")#ni- b%ood

"o#,&%#tion9 To +no' "%!#r%y t)! %o"#% #nd ,!n!r#% $#"tor ')i") (ro-ot! t)! $or-#tion o$ t)! t)ro-b&

: To +no' -or()o%o,y o$ # t)ro-b& #nd it ty(! in d!(!nd!n"! o$ tr&"t&r! #((!#r#n"! #nd

t)! #ttit&d! to t)! %&-!n o$ t)! *!!%

; To +no' (oib%! o&t"o-! o$ t)ro-boi #nd it *#%&! $or #n or,#ni-

6 To +no' d!$inition o$ !-bo%i- #nd it ty(! in d!(!nd!n"! o$ ")#r#"t!r o$ -otion #nd t)!

n#t&r! o$ !-bo%&!

@ To b! #b%! to ,i*! t)! bri!$ ")#r#"t!riti" o$ *#rio& +ind o$ !-bo%i-. to +no' t)! "#&! o$

t)!ir d!*!%o(-!nt. *#%&! #nd (oib%! o&t"o-!

To +no' d!$inition o$ t)! in$#r"t. t)! "#&! o$ it d!*!%o(-!nt #nd t#,!

To +no' #bo&t t)! $#"tor. ')i") in$%&!n"! on d!*!%o(-!nt o$ in$#r"t

40 To +no' t)! ty(! o$ in$#r"t in d!(!nd!n"! on t)! $or-. "o%o&r. onit!n"! #nd t)! i!To b! #b%! to ,i*! ,ro #nd -i"ro"o(i"#% ")#r#"t!riti" o$ in$#r"t in *#rio& %o"#%i#tion

44 To +no' (oib%! o&t"o-! o$ #n in$#r"t #nd it *#%&! $or or,#ni-

42 To +no' d!$inition o$ "on"!(t >)o"+>. it ty(!. t)! -#in -or()o%o,i"#% !5)ibitin, #nd

"on"r!t! ")#n,! in # +idn!y. %i*!r. %&n, #nd in t)! -yo"#rdi&-

LABORATORY WORK № '

GROSS SPECIMENS:

4? M&%ti(%! i")!-i" in$#r"t o$ +idn!y

2? H!-orr)#,i" in$#r"t o$ %&n,

9? M&r#% t)ro-b& o$ t)! #ort#

:? M!t#t#i! o$ "#n"!r o$ t)! (#n"r!# in %&n,

MICROSLIDES3

@? An!-i" /(#%! in$#r"t o$ # +idn!y

4? O""%&i*! or,#ni!d t)ro-b& o$ #rt!ri# 'it) # "#n#%i#tion

6;? Ly-()o,!no& -!t#t#i! o$ # "#n"!r in %&n,

№ ' ANEMIC )PALE INFARCT OF A KIDNEYS.

Yo& "#n $ind 9 on! #t t)! %o' -#,ni$i"#tion3

4 Qon! o$ n!"roi3 Yo& "#n $ind t)! "onto&r o$ d!n&"%!#ri!d ,%o-&%&!

2 T)! ri- on!3 not #%'#y ditin"t%y !5(r!!d. in ')i") #r! *iib%!)#r(%y di%#t!d b%ood *!!%

#nd !ryt)ro"yt! #ro&nd t)! *!!% /b!t'!!n t&b&%!. in # %&-!n o$ t&b&%!9 Nor-#% ti&! o$ +idn!y

D!i,n#tion3

4? Qon! o$ n!"roi3 # d!n&"%!#ri!d ,%o-&%&. b d!n&"%!#ri!d t&b&%!

2? T)! ri- on!3 di%#t!d b%ood *!!%. b )!-orr)#,!

9? Nor-#% ti&! o$ +idn!y

№ (% LYMPHOGENOUS METASTASISES OF A CANCER IN LUNGS.

In t)! ti&! o$ %&n, yo& "#n $ind di%#t!d b%ood *!!%. )ydro(i" $%&id in %&-!n o$ #%*!o%&!

In *#rio& $i!%d o$ %&n,? in &b(%!&r#%. (!ri*#"&%#r #nd (!ribron")i#% d!(#rt-!nt #r! *iib%!

n&-!ro&.di%#t!d %y-()#ti" *!!% 'it) di$$!r!nt "#%ibr!r. ')i") %&-!n #r! $i%%!d 'it) "o-(%!5!

o$ "#n"!r "!%% D&! to !-bo%i" (ro"! in # (&%-on#ry ti&! n&-!ro& %y-()o,!no& -!t#t#i!o$ #n &ndi$$!r!nti#t!d "#n"!r )#*! #((!#r!d

D!i,n#tion3



4 Di%#t!d b%ood *!!%

2 Hydro(i" $%&id in %&-!n o$ #%*!o%&!

9 C#n"!ro& !-bo%& in t)! %&-!n o$ %y-()#ti" *!!%

№ &1 OCCLUSIVE ORGANI7ED THROMBUS OF ARTERIAS WITH A

CANALI7ATION.

In t)! -i"ro%id! yo& "#n !! "ro !"tion o$ t)! #rt!ri#T)! %&-!n o$ #rt!ri# in$i%%!d by t)!"onn!"ti*! ti&!. ')i") #r! r!(%#"! t)! o""%&i*! t)ro-b& T)! bord!r b!t'!!n #n inti-# #nd

onn!"ti*! ti&! i in*iib%! A-on, "onn!"ti*! ti&! #r! *iib%! -&%ti(%! -#%% #nd i-(%! %#r,!

#*iti!. t&rnin, into *!!% In t)! "!nt!r o$ # t)ro-b& t)! $o"&! o$ #!(ti" #&to%yi #r! ti%%

(r!!r*!d

D!i,n#tion3

4 Conn!"ti*! ti&!

2 M&%ti(%! -#%% #nd i-(%! %#r,! "#*iti!. t&rnin, into *!!%

9 T)! $o"&! o$ #!(ti" #&to%yi

№ ' ANEMIC )PALE INFARCT OF A KIDNEYS.

t#inin,3 # )!-#to5y%in !oin -#,ni$i"#tion3

D!i,n#tion3

4? Qon! o$ n!"roi3 # d!n&"%!#ri!d ,%o-&%&. b d!n&"%!#ri!d t&b&%!

2? T)! ri- on!3 di%#t!d b%ood *!!%. b )!-orr)#,!

9? Nor-#% ti&! o$ +idn!y

№ (% LYMPHOGENOUS METASTASISES OF A CANCER IN LUNGS.


-#,ni$i"#tion3

D!i,n#tion3

4 Di%#t!d b%ood *!!%

2 Hydro(i" $%&id in %&-!n o$ #%*!o%&!

9 C#n"!ro& !-bo%& in t)! %&-!n o$ %y-()#ti" *!!%



№ &1 OCCLUSIVE ORGANI7ED THROMBUS OF ARTERIAS WITH A

CANALI7ATION.


-#,ni$i"#tion3

D!i,n#tion3

4 Conn!"ti*! ti&!

2 M&%ti(%! -#%% #nd i-(%! %#r,! "#*iti!. t&rnin, into *!!%

9 T)! $o"&! o$ #!(ti" #&to%yi

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: TISSUE RESPONSES TO

DAMAGE. ACUTE INFLAMMATION.


4 To +no' d!$inition o$ #n in$%#--#tion

2 To +no' int!,r#t! ()#! /"o-(on!nt. (#t)o,!n!ti" -!")#ni- o$ in$%#--#tion

9 To b! #b%! to %it (rin"i(#% "#&! o$ #n in$%#--#tion

: To +no' #bo&t "%ini"#% #ttrib&t! o$ #n in$%#--#tion

; To +no' #bo&t )or-on#% #nd n!r*o& $#"tor o$ r!,&%#tion o$ #n in$%#--#tion

6 To +no' #bo&t t!r-ino%o,y o$ #n in$%#--#tion

@ To +no' -or()o%o,i"#% $or- o$ t)! in$%#--#tion #nd t)! (rin"i(%! o$ t)!ir "%#i$i"#tion

To b! #b%! to %it #%% +ind o$ !5&d#ti*! in$%#--#tion 'it) t)! (oint o$ *i!' o$ # (rin"i(%!

o$ "%#i$i"#tion

To +no' -or()o%o,i"#% $!#t&r! o$ !ro&. $ibrino&. "#t#rr)#%. (&trid. )!-orr)#,i" #nd t)!

-i5!d $or- o$ in$%#--#tion /t)!ir %o"#%i#tion. "o&r!.t)! "#&!. o&t"o-! #nd *#%&! $or t)!

or,#ni-

LABORATORY WORK № &

GROSS SPECIMENS:4? P&r&%!nt %!(to-!nin,iti

2? Fo"#% (&r&%!nt bron")o(n!&-oni#

9? Fibrino& (!ri"#rditi

:? M&%ti(%! #b"!! o$ # br#in in # !(ti"o(y!-i#

MICROSLIDES:

:2? P&r&%!nt -!nin,iti

:4? Fibrino& (!ri"#rditi

40:? Fo"#% !ro(&r&%!nt (n!&-oni#



№ 3". PURULENT MENINGITIS.

T)! (i# -#t!r o$ br#in )#r(%y t)i"+!n. -#in%y d&! to t)! #b&nd#nt "ont!nt o$ (&r&%!nt

!5&d#tion. ')i") "onit o$ -#ny %!&"o"yt! T)! *!!% (i# -#t!r #r! )#r(%y di%#t!d. (%!t)ori".

#ro&nd o$ t)!- #b&nd#nt (!ri*#"&%#r in$i%tr#t! T)! ti&! o$ # br#in do! not ")#n,!d

D!i,n#tion3

4 P&r&%!nt !5&d#tion in (i# -#t!r o$ br#in

2 P%!t)ori" *!!% 'it) (!ri*#"&%#r in$i%tr#t!9 Ti&! o$ # br#in

№ 143. FOCAL SEROPURULENT PNEUMONIA.

L&-!n o$ #%*!o%&! #r! $i%%!d 'it) !5&d#tion o$ *#rio& "o-(oition o-! #%*!o%&! $i%%!d

'it) )o-o,!n!o& (rot!in#"!o& -#. ')i") #r! &ni$or-%y t#in!d by !oin! in (in+ "o%o&r

i-(%! %!&"o"yt! #nd "!%% !nt!r into "o-(oition o$ t)i !5&d#tion In -#ny ot)!r #%*!o%&! in

"o-(oition o$ !5&d#tion do-in#t! n!&tro()i% %!&"o"yt! t)#t ")#r#"t!ri! # (&r&%!nt

in$%#--#tion Pr!!n"! in t)! #-! -i"ro%id! t)! $o"&! o$ # !ro& #nd (&r&%!nt in$%#--#tion

=&ti$i! t)! n#-! o$ &") (n!&-oni#? -i5!d/!ro(&r&%!nt In int!r#%*!o%#r !(t&- t)!r! #r!

)#r(%y di%#t!d. (%!t)ori" *!!%

D!i,n#tion34 !ro& !5&d#tion in # %&-!n o$ #%*!o%&!

2 P&r&%!nt !5&d#tion in # %&-!n o$ #%*!o%&!

№ 31. FIBRINOUS PERICARDITIS.

In # -i"ro%id! it i (oib%! to $ind # -yo"#rdi&- #nd $ibrino& -!-br#n! on t)! !(i"#rdi&- In

#n !(i"#rdi&- it i (oib%! to !! )#r(%y di%#t!d. (%!t)ori" *!!% #nd # #""&-&%#tion ro&nd t)!-

*#rio& "!%% T)! !(i"#rdi&- b!"o-! t)i"+!r d&! to ,r#n&%#tion ti&! ')i") "onit o$ "#(i%%#r

#nd "!%% ')i") #r! &rro&nd t)!-. -#in%y -#"ro()#,! #nd $ibrob%#t T)! &nditort!d $ibrin %#y

# r#t)!r t)i"+ tr#nd #nd %&-(. #nd t#in!d 'it) !oin! (in+ "o%o&r

D!i,n#tion3

4 Myo"#rdi&-

2 Fibrino& -!-br#n! on t)! !(i"#rdi&-

9 Gr#n&%#tion ti&!

: C#(i%%#r in ,r#n&%#tion ti&!

; M#"ro()#,! #nd $ibrob%#t

№ 3". PURULENT MENINGITIS.


-#,ni$i"#tion3

D!i,n#tion3

4 P&r&%!nt !5&d#tion in (i# -#t!r o$ br#in

2 P%!t)ori" *!!% 'it) (!ri*#"&%#r in$i%tr#t!

9 Ti&! o$ # br#in



№ 143. FOCAL SEROPURULENT PNEUMONIA.


-#,ni$i"#tion3

D!i,n#tion3

4 !ro& !5&d#tion in # %&-!n o$ #%*!o%&!

2 P&r&%!nt !5&d#tion in # %&-!n o$ #%*!o%&!

№ 31. FIBRINOUS PERICARDITIS.


D!i,n#tion3

4 Myo"#rdi&-

2 Fibrino& -!-br#n! on t)! !(i"#rdi&-

9 Gr#n&%#tion ti&!

: C#(i%%#r in ,r#n&%#tion ti&!

; M#"ro()#,! #nd $ibrob%#t

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: PRODUCTIVEINFLAMMATION: INTERSTITIAL, GRANULOMATOUS, WITH POLYPS FORMATION.


4 To +no' d!$inition. t)! ,!n!r#% -or()o%o,i"#% ")#r#"t!riti" #nd "%#i$i"#tion o$

(rod&"ti*! in$%#--#tion

2 To +no' %o"#%i#tion. t)! "#&! #nd t)! -or()o%o,i"#% ")#r#"t!riti" o$ #n int!rtiti#%

in$%#--#tion 'it) $or-#tion o$ (o%y( #nd (oint!d "ondy%o-#

9 To +no' "%#i$i"#tion #nd -or()o%o,y ,r#n&%o-#to& in$%#--#tion S #"&t! #nd

(!rit!nt in$!"tion. #nd ,i*! t)! !5#-(%! o$ b#i" di!#! $ro- t)i ,ro&(

: To +no' #bo&t t#,! o$ d!*!%o(-!nt #nd ro&t! o$ in$!t#tion in !")ino"o""oi.

"yti"!r"oi #nd tri")inoi

; To +no' -or()o%o,y o$ t)! "on$or-in, (#r#it! #nd (!ri$o"#% )iti" r!#"tion in t)!! (#r#itoi!

6 To +no' $!#t&r! o$ (!"i$i" $or- o$ in$%#--#tion #nd to %it di!#! in ')i") it #ri!



@ To +no' t)! !tio%o,y. %o"#%i#tion. t)! -or()o%o,i"#% ")#r#"t!riti" o$ # (!"i$i"

in$%#--#tion in # t&b!r"&%oi. %!(roy. "%!ro-#

To +no' -or()o%o,i"#% $!#t&r! (ri-#ry. t)! !"ond#ry #nd t!rti#ry. #nd #%o # "on,!nit#%

y()i%i

LABORATORY WORK № $

GROSS SPECIMENS:4? E")ino"o""& o$ # %i*!r

2? Cyti"!r"oi o$ # br#in

9? Mi%i#ry t&b!r"&%oi o$ t)! %&n,

:? y()i%iti" #ortiti 'it) #n #n!&ry- #nd r&(t&r!

MICROSLIDES:

:6? Ttri")inoi

:? "%!ro-#

;2? Mi%i#ry t&b!r"&%oi o$ t)! %&n,

№ 3(. TRICHINOSIS.

M#ny $ib!r o$ # tri#t!d -&"%! i (ind%!? )#(!d%y '!%%!d Inid! in$%#tion yo& "#n !! t)!

(#r#it! tri")in#. t#in!d 'it) )!-#to5y%in in *io%!t "o%o&r T)! (#r#it! i &rro&nd!d d!n!"onn!"ti*! ti&! -!-br#n! ')i") i i-(r!,n#t!d 'it) #%t o$ %i-! #nd t#in!d 'it) )!-#to5y%in

in *io%!t "o%o&r

D!i,n#tion3

4 P#r#it! inid! # -&"%! $ib!r

2 C#%"i$i!d "onn!"ti*! ti&! -!-br#n!

9 A r!#"ti*! in$%#--#tion #ro&nd o$ t)! (#r#it!

№ 3&. SCLEROMA.

In t)! %id! yo& "#n $ind $i!%d o$ # -&"o& %#ryn5 "o#t!d 'it) 1&#-o! !(it!%i&- In

&nd!r%yin, ti&! yo& "#n $ind ,ro't) o$ (!"i$i" ,r#n&%#tion ti&! "ontr&"t!d -#in%y $ro-

(%#-# "!%% 'it) #n #d-i5in, o$ $ibrob%#t #nd %y-()oid "!%% Und!r #n !(it)!%i#% %#y!r #nd in

ot)!r $i!%d yo& "#n !! (%!nty %#r,! "!%% 'it) %i,)t "yto(%#- /Mi+&%i") "!%% #nd )o-o,!n!o&.

t#in!d in (in+ "o%o&r. ro&nd b#%%?)#(!d $or-#tion? #"ido()i%i" )y#%in! b#%%

D!i,n#tion3

4 P%#-# "!%%

2 Mi+&%i") "!%%

9 Hy#%in! b#%%

№ %". MILIARY TUBERCULOSIS OF THE LUNGS.

In t)! %id! yo& "#n $ind # (&%-on#ry ti&! 'it) -&%ti(%! ,r#n&%o-# # (i-(%! ')i") ,ro&nd

-# i "o-(o&nd!d 'it) !(it)!%ioid "!%% A-on, t)!- -!!t on! or t'o ,i,#nt -&%tin&"%!#t!"!%% Piro,o*?L#n)#n"! 'it) %o"#tin, o$ n&"%!& # # (#%in, on (!ri()!ry o$ # "!%% In (!ri()!ri"

d!(#rt-!nt o$ # ,r#n&%o-# t)! )#$t $ro- %y-()oid "!%% 'it) # -#%% #d-i5in, o$ (%#-#"yt! i

$o&nd o&t In t)! "!nt!r o$ o-! ,r#n&%o-# $o"&! o$ "#!o& n!"roi #r! $o&nd o&t o-!

,r#n&%o-# -!r,! #-on, t)!-!%*!. $or-in, *#rio& on i! #nd t)! $or- "on,%o-!r#t!

D!i,n#tion3

4 E(it)!%ioid%y "!%%&%#r ,r#n&%o-#3

E(it)!%ioid "!%%

Gi,#nt -&%tin&"%!#t! "!%% Piro,o*?L#n)#n"!

Ly-()oid "!%%

2 Fo"&! o$ "#!o& n!"roi in t)! "!nt!r o$ ,r#n&%o-#



№ 3(. TRICHINOSIS.


-#,ni$i"#tion3

D!i,n#tion3

4 P#r#it! inid! # -&"%! $ib!r

2 C#%"i$i!d "onn!"ti*! ti&! -!-br#n!

9 A r!#"ti*! in$%#--#tion #ro&nd o$ t)! (#r#it!

№ 3&. SCLEROMA.


-#,ni$i"#tion3

D!i,n#tion3

4 P%#-# "!%%

2 Mi+&%i") "!%%

9 Hy#%in! b#%%

№ %". MILIARY TUBERCULOSIS OF THE LUNGS.


-#,ni$i"#tion3

D!i,n#tion3

D!i,n#tion3

4 E(it)!%ioid%y "!%%&%#r ,r#n&%o-#3

E(it)!%ioid "!%%

b Gi,#nt -&%tin&"%!#t! "!%% Piro,o*?L#n)#n"!

" Ly-()oid "!%%

2 Fo"&! o$ "#!o& n!"roi in t)! "!nt!r o$ ,r#n&%o-#

i,n#t&r! o$ t!#")!r3 D#t!3



EDUCATIONAL-TARGET QUESTIONS ON THE THEME: IMMUNOPATHOLOGOCAL

PROCESSES.


4 To ,i*! # d!$inition to i--&no(#t)o%o,i"#% (ro"!!. to n#-! t)!-

2 To ")#r#"t!ri! ")#n,! o$ i--&no"o-(!t!nt yt!- #t #nti,!n ti-&%#tion #nd i--&n!

d!$i"i!n"y9 To ,i*! t)! ")#r#"t!riti" to )y(!r!niti*ity r!#"tion

: To ,i*! # d!$inition to #&toi--&ni#tion. #&toi--&n! diord!r. to n#-! t)!-. to ,i*! t)!ir

-or()o%o,i"#% ")#r#"t!riti"

; To ,i*! # d!$inition to i--&nod!$i"i!n"y yndro-. to n#-! t)!-. to ")#r#"t!ri! t)!ir

-or()o%o,y

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: TISSUE REPAIR,

ORGANI7ATION, HYPERTROPHY, HYPERPLASIA, ATROPHY, METAPLASIA


4 To ditin,&i) !!n"! o$ t)! #d#(t#tion #nd "o-(!n#tion

2 To n#-! t#,! o$ "o-(!n#tory #d#(t#tion. to ,i*! t)!ir -or()o%o,i"#% ")#r#"t!riti"9 To n#-! #nd d!$in! di$$!r!nt +ind o$ r!,!n!r#tion. to !5(%#in t)! -!")#ni- o$ t)!ir

d!*!%o(-!nt

: To ditin,&i) +ind o$ r!,!n!r#tion on t)! b#i ,ro. t)! -i"ro"o(i" #nd &%tr#tr&"t&r#%

")#r#"t!riti"

; To !5(%#in (ro"! o$ t)! or,#ni#tion #nd it $&n"tion#% *#%&!

6 To n#-! #nd d!$in! *#rio& +ind o$ t)! #d#(t#tion #nd "o-(!n#tion. to !5(%#in t)!

-!")#ni- o$ t)!ir d!*!%o(-!nt

@ To ditin,&i) t)! +ind o$ "o-(!n#tory #d#(t#tion (ro"!! b#!d on -#"ro"o(i"#%.

-i"ro"o(i" #nd &%tr#tr&"t&r#% ")#r#"t!riti"

To !5(%#in $&n"tion#% *#%&! o$ #d#(t#tion #nd "o-(!n#tion (ro"!!


GROSS SPECIMENS:

4? Hy(!rtro()y o$ t)! )!#rt

2? Potin$#r"tion "#r o$ -yo"#rdi&- /in"o-(%!t! r!,!n!r#tion

9? Co%%oid ,oit!r

:? Hy(!rtro()y o$ &rin#ry b%#d!r '#%% d&! to #d!no-# o$ (rot#t!

;? Bro'n #tro()y o$ %i*!r

MICROSLIDES

;;? G%#nd&%#r )y(!r(%#i# o$ t)! !ndo-!tri&-

;@? Hy("rtro()y o$ t)! -yo"#rdi&-40? Co%%oid ,oit!r /)y(!rtro()y o$ t)yroid ,%#nd

№%% GLANDULAR HYPERPLASIA OF THE ENDOMETRIUM

)o' ,r!#t%y t)i"+!n!d !ndo-!tri&-. ')i") i ")#r#"t!ri!d by #n in"r!#! in t)! n&-b!r o$

"!%% in !#") ,%#nd T)! ,%#nd )#*! t'ity )#(! /#'?toot)!d. "or+"r!'?%i+!8 o-! o$ t)!- )#*!

di%#t!d %&-!n #nd #((!#r#n"! o$ "yt T)! ,%#nd !(it)!%i&- (ro%i$!r#t!8 t)! tro-# i r!#") by

"!%%&%#r !%!-!nt

D!i,n#tion3

4 Myo-!tri&-

2 Endo-!tri&-

9 G%#nd 'it) t'ity )#(! /#'?toot)!d. "or+"r!'?%i+!



№%' HYPERTROPHY OF THE MYOCARDIUM

C#rdi#" -&"%! "!%% o$ )y(!rtro()i!d -yo"#rdi&- #r! in"r!#!d Not! t)#t t)! n&"%!i in t)!

)y(!rtro()i!d "#rdi#" -&"%! #r! #%o in"r!#!d #nd t)!y #r! )y(!r")ro-i# T)!r! #r! -#ny b%ood

*!!% in t)! !n%#r,!d tro-#

D!i,n#tion3

4 In"r!#!d "#rdi#" -&"%! "!%%

2 In"r!#!d in i! n&"%!i

№%' COLLOID GOITERS )HYPERTROPHY OF THYROID GLAND

T)! t)yroid ti&! i "o-(o!d o$ )y(!r(%#ti" t)yroid #"ini M#ny "ont#in ,!%#tino& "o%%oid.

ot)!r #r! o%id #nd "r!#- "o%or!d Cyti" d!,!n!r#tion i "o--on T)! $o%%i"%! !(it)!%i&- i

$%#tt!n!d. #tro()i!d

D!i,n#tion3

4 In"r!#!d in i! t)yroid #"ini

№%% GLANDULAR HYPERPLASIA OF THE ENDOMETRIUM


-#,ni$i"#tion3

D!i,n#tion3

4 Myo-!tri&-

2 Endo-!tri&-

9 G%#nd 'it) t'ity )#(! /#'?toot)!d. "or+"r!'?%i+!

№%' HYPERTROPHY OF THE MYOCARDIUM


-#,ni$i"#tion3

D!i,n#tion3

4 In"r!#!d "#rdi#" -&"%! "!%%

2 In"r!#!d in i! n&"%!i



№%' COLLOID GOITERS )HYPERTROPHY OF THYROID GLAND


-#,ni$i"#tion3

D!i,n#tion3

4 In"r!#!d in i! t)yroid #"ini

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: GENERAL INFORMATION.

EPITHELIAL: BENIGN AND MALIGNANT


4 To ,i*! # d!$inition to t&-or

2 To !5(%#in -or()o%o,i"#% $!#t&r! o$ t&-or "!%%

9 To ")#r#"t!ri! (rin"i(%! o$ t&-or "%#i$i"#tion

: To ditin,&i) b!ni,n #nd -#%i,n#nt t&-or on t)! b#i o$ -or()o%o,i"#% $!#t&r!

; To n#-! b!ni,n #nd -#%i,n#nt t&-or

6 To !5(%#in -!t#t#i! (r!#d (#t)'#y o$ -#%i,n#nt !(it)!%i#% t&-or


GROSS SPECIMENS:

4? +in (#(i%%o-#

2? L#ryn5 "#n"!r? # t&-or#% ti&! o$ ,r#y ? (in+ "o%o&r 'it) # ro&,). br!#+in, &( &r$#"! ,ro'

!5o()yti!%y in t)! %&-!n o$ %#ryn5

9? Endo-!tri#% #d!no"#r"ino-#? t&-or#% $or-#tion ,ro'in, $ro- # -&"o i *iib%! on !"tion It

i ,r!y ? r!d "o%o&r. 'it) # ro&,) &r$#"!. on ')i") (%&r#% &%"!r#tion #r! $o&nd o&t

:? M!t#t#! o$ "#n"!r in %i*!r

;? #&"!r?)#(!d "#n"!r o$ to-#")? t)! t&-or %oo+ %i+! ()!ri"#% !i%! $or-#tion 'it) t)! r#i!d

bo%t!r?)#(!d !d,! #nd %o' botto-6? Di$$&! ,#tri" "#r"ino-#? -&"o& #nd &b-&"o& %#y!r #r! )#r(%y t)i"+!n!d on #%% !5t!nt o$

to-#") '#%%. on !"tion t)!y #r! ')it! M&"o#% &r$#"! i ro&,). it $o%d )#*! di$$!r!nt d!(t).

#nd t)! %&-!n o$ to-#") i n#rro'!d

@? C!ntr#% %&n, "#n"!r ? # t&-or#% nod%! o$ ')it!?(in+ "o%o&r 'it) ro&,) "onto&r i !!n in )i%& o$

t)! %&n, Lob#r bron")& -&"o i t&b!ro& in r#n,! o$ t&-o&r

MICROSLIDES

;?#? +in (#(i%%o-#

62? 1&#-o& "!%% "#r"ino-# 'it) +!r#tini#tion

6@? Co%on "#n"!r

6:? In$i%tr#ti*! d&"t#% br!#t "#n"!r /"irr)o& K$ibro& "#r"ino-#66? M!t#t#! o$ "#n"!r in %i*!r



№%&-A SKIN PAPILLOMA.

N&-!ro& o&t,ro't) o$ 1&#-o& !(it)!%i&- #r! *iib%!. ')i") "o-(o&nd (#r!n")y-# o$

t&-o&r T&-oro& tro-# &b-itt!d by o&t,ro't) o$ d!r-# i '!%% -#r+!d in t&-or T)i

o*!r,ro't) %oo+ %i+! ,%o*! $in,!r. #nd #r! "o*!r!d by 1&#-o& !(it)!%i&- T)! ")#r#"t!riti" o$

(#(i%%o-# # # b!ni,n t&-or i )iti" #ty(i# It i di(%#id in in"r!#in, o$ !(it)!%i&- %#y!r. ')i")

n&-b!r i di$$!r!nt in #ny on! o$ t&-or T)! irr",&%#ry in"r!#!d +!r#tini#tion /)y(!r+!r#toi

!5(r!!d tro-# i #%o #d*#n"!d irr!,&%#r%y Ho'!*!r. (#(i%%o-# (ro(!rti! +!!( $!#t&r! o$ nor-#% !(it)!%i&- /"!%% (o%#rity. "o-(%!5ity. (r!!n"! o$ b##% -!-br#n! P#(i%%o-# -#y ,ro'

on +in. -&"o& "o*!r!d by non+!r#toi" (#*!-!nt or tr#niti*! !(it)!%i&-3 #n or#% "#*ity -&"o&.

#n !o()#,&. tr&! *o"#%. #nd &rin#ry b%#dd!r B%!!din, -#y b! # # r!&%t o$ &rin#ry b%#dd!r

(#(ii%o-# P#(i%%o-# -#y r!"&r #nd )#*! -#%i,n#nt d!,!n!r#tion o-!ti-!

D!i,n#tion3

4 Conn!"ti*! ti&! (#(i%%#!

2 1&#-o& !(it)!%i&-

№(" SQUAMOUS CELL CARCINOMA WITH KERATINI7ATION.

T)! t&-o&r "onit $ro- b#nd #nd %#y!r o$ #n #ty(i"#% $%#t !(it)!%i&- ')i") ,ro' into

&b=!"tin, d!r-# Attrib&t! o$ (o%y-or()i" "!%% 'it) )y(!r")ro-#ti" di$$!r!nt i! n&"%!&.

+!!(in, t'o or -or! n&"%!o%&! #r! *iib%! #t t)! bi, #&,-!nt#tion Fi,&r! o$ (#t)o%o,i"#%-itoi! #r! $o&nd o&t B&%b#r tr&"t&r! $ro- +!r#toi" "!%% "#n"!r (!r% #r! *iib%! in "!nt!r o$

t&-or#% o"+!t T)!y #r! ")#r#"t!riti" -or()o%o,i"#% -#r+!r o$ 1&#-o& +!r#toi" "#n"!r

D!i,n#tion3

4 Po%y-or()i" "#n"!r "!%% 'it) )y(!r")ro-#ti" di$$!r!nt i! n&"%!&

2 C#n"!r (!r%

9 Conn!"ti*! ti&! tro-#

№ (' COLON CANCER.

O*!r,ro't) o$ #ty(i"#% ,%#nd #r! *iib%! in #%% %#y!r o$ "o%on '#%% T)!r! #r! "!%%. $or-in,

,%#nd o$ *#rio& i! #nd $or-. 'it) )y(!r")ro-#ti" n&"%!& #nd (#t)o%o,i"#% -itoi! $i,&r!

D!i,n#tion3

4 Nor-#% -&"o&# o$ "o%on

2 C#n"!r "!%%

№(3- INFILTRATIVE DUCTAL BREAST CANCER )SCIRRHOUS 5FIBROUS6

CARCINOMA.

T)! t&-o&r "onit $ro- in,%! or ,ro&(! o$ "#n"!r "!%% o$ *#rio& i! #nd $or-. 'it)

)y(!r")ro-#ti" n&"%!& #nd (#t)o%o,i"#% -itoi! $i,&r! It i !!n (r!do-in#n"! o$ "onn!"ti*!

ti&! tro-# on !(it)!%i#% "o-(on!nt

D!i,n#tion3

4 tro-#2 C#n"!r "!%%

№((- METASTASES OF CANCER IN LIVER.

In %i*!r ti&! yo& "#n $ind #ty(i"#% ,%#nd #r! *iib%! *#rio& i! #nd $or-. 'it)

)y(!r")ro-#ti" n&"%!& #nd (#t)o%o,i"#% -itoi! $i,&r!

D!i,n#tion3

4 Li*!r ti&!

2 Aty(i"#% ,%#nd



№%&-A SKIN PAPILLOMA.


-#,ni$i"#tion3

D!i,n#tion3

4 Conn!"ti*! ti&! (#(i%%#!

2 1&#-o& !(it)!%i&-

№(" SQUAMOUS CELL CARCINOMA WITH KERATINI7ATION.


D!i,n#tion3

4 Po%y-or()i" "#n"!r "!%% 'it) )y(!r")ro-#ti" di$$!r!nt i! n&"%!&

2 C#n"!r (!r%

9 Conn!"ti*! ti&! tro-#

№ (' COLON CANCER. t#inin,3 # )!-#to5y%in !oin

-#,ni$i"#tion3

D!i,n#tion3

4 Nor-#% -&"o&# o$ "o%on2 C#n"!r "!%%



№(3- INFILTRATIVE DUCTAL BREAST CANCER )SCIRRHOUS 5FIBROUS6

CARCINOMA.


-#,ni$i"#tion3

D!i,n#tion3

4 tro-#

2 C#n"!r "!%%

№((- METASTASES OF CANCER IN LIVER.


-#,ni$i"#tion3

D!i,n#tion3

4 Li*!r ti&!

2 Aty(i"#% ,%#nd

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: TUMORS.

ORGANOSPECIFIC EPITHELIAL TUMOURS


4 To n#-! or,#no(!"i$i" !(it)!%i#% t&-o&r

2 To ,i*! t)! -or()o%o,i"#% ")#r#"t!riti" o$ or,#no(!"i$i" !n"%o? #nd !5o?"rini" ,%#ndt&-o&r /(in!#% ,%#nd. #dr!n#%. (#n"r!#. &t!r&

9 To ,i*! t)! -or()o%o,i"#% ")#r#"t!riti" o$ or,#no(!"i$i" t&-o&r /br!#t. +idn!y. %i*!r.

+in. o*#ry. t!ti"%!. GIT

: To !5(%#in ")#r#"t!r o$ -#%i,n#nt !(it)!%i#% t&-o&r -!t#t#ti" (r!#d

LABORATORY WORK № 1"

GROSS SPECIMENS:

4? C)orio"#r"ino-# /")orion!(it)!%io-# ? t)! t&-o&r %oo+ %i+! d#r+ "o%or nod!. 'it) (on,i$or-

tr&"t&r!. t)! %o"&i o$ )!-orr)#,! #r! *iib%! in it C)orion!(it)!%io-# ,i*! !#r%y )!-#to,!no&

-!t#t#i!. $irt o$ #%% in %&n,

2? Hyd#tidi$or- -o%!9? R!n#% "!%% "#r"ino-#

:? C#n"!r o$ t)! t)yroid ,%#nd



;? Br!#t "#n"!r

6? !-ino-#

@? !ro&! "yt#d!no-# o$ o*#ri!

MICROSLIDES

0? C)orio"#r"ino-# /")orion!(it)!%io-#

@:? Hyd#tidi$or- -o%! D!-ontr#tion

492? R!n#% "!%% "#r"ino-#4;? Fibro#d!no-# o$ t)! br!#t

№&4 CHORIOCARCINOMA )CHORIONEPITHELIOMA.

T)! t&-o&r i "ontr&"t!d $ro- t&-or#% "!%% o$ t'o ty(!3 -ono-or()i" %i,)t !(it)!%i#%

/L#n,)#n #nd ,i#nt di*idin, "!%% 'it) )y(!r")ro-#ti" (o%y-or()i" n&"%!&

/yn"ytiotro()ob%#t T)! tro-# in t&-o&r i #b!nt8 "#*iti! $i%%!d 'it) !ryt)ro"yt! #r! *iib%!

int!#d o$ *!!% #%% o$ "#*iti! #r! "o*!r!d by t&-or#% "!%% int!#d o$ "ndot)!%i&-

4 Li,)t !(it)!%i#% /L#n,)#n "!%%

2 yn"ytiotro()ob%#t

№1#" RENAL CELL CARCINOMA )C8/+0 9/88 /. T)i i t)! -ot "o--on (#tt!rn T)! "%!#r "yto(%#- o$ t&-o&r "!%% i d&! to r!-o*#% o$

,%y"o,!n #nd %i(id $ro- t)! "yto(%#- d&rin, (ro"!in, o$ ti&! T)! t&-o&r "!%% )#*! # *#ri!ty

o$ (#tt!rn3 o%id. tr#b!"&%#r #nd t&b&%#r. !(#r#t!d by d!%i"#t! *#"&%#t&r! M#=ority o$ "%!#r "!%%

t&-o&r #r! '!%% di$$!r!nti#t!d

4 T&-o&r "!%% 'it) "%!#r "yto(%#-

2 Conn!"ti*! ti&! tr#t&-

№1%- FIBROADENOMA OF THE BREAST.

P#r!n")y-# o$ t&-o&r i &b-itt!d by ,%#nd&%#r "o-(%!5! o$ t)! *#rio& $or- #nd i!. #nd

tro-# by intr#%ob&%#r ,ro't) o$ "onn!"ti*! ti&!. ')i") (r!do-in#t! #bo*! ,%#nd&%#r

"o-(on!nt Ad!no-# i "#%%!d # intr#"#n#%i"&%#r $ibro#d!no-#. i$ it ,ro' in d&"t '#%% #nd

"o-(r!!d t)! %&-!n by "onn!"ti*! ti&! D&"t o$ &") #d!no-# %oo+ %i+! n#rro' "%!$t

Fibro#d!no-# o$ t)! br!#t r!$!r to dy)or-on#% )y(!r(%#i# #nd "onid!r # or,#no(!"i$%"

t&-or

4 Intr#%ob&%#r ,ro't) o$ "onn!"ti*! ti&!

2 Co-(r!!d %&-!n o$ ,%#nd

№&4 CHORIOCARCINOMA )CHORIONEPITHELIOMA.


-#,ni$i"#tion3

D!i,n#tion3

4 Li,)t !(it)!%i#% /L#n,)#n "!%%

2 yn"ytiotro()ob%#t



№1#" RENAL CELL CARCINOMA )C8/+0 9/88 /.


-#,ni$i"#tion3

D!i,n#tion3

4 T&-o&r "!%% 'it) "%!#r "yto(%#-

2 Conn!"ti*! ti&! tr#t&-

№1%- FIBROADENOMA OF THE BREAST.


-#,ni$i"#tion3

D!i,n#tion3

4 Intr#%ob&%#r ,ro't) o$ "onn!"ti*! ti&!

2 Co-(r!!d t)! %&-!n o$ ,%#nd

i,n#t&r! o$ t!#")!r3 D#t!3

EDUCATIONAL-TARGET QUESTIONS ON THE THEME: MESENCHYMAL

NEOPLASMS. TUMORS OF THE CENTRAL NERVOUS SYSTEM.

MELANOCYTE NEOPLASMS.


4 To n#-! b!ni,n #nd -#%i,n#nt -!!n")y-#% n!o(%#-. to ,i*! t)!ir -or()o%o,i"#%

d!"ri(tion2 To n#-! b!ni,n #nd -#%i,n#nt -!i#no"yti" n!o(%#-. to ")#r#"t!ri! t)!y

9 To !5(%#in -!t#t#i (r!#d (#t)'#y o$ -!!n")y-#% #nd -!i#no"yti" n!o(%#-

: To n#-! b!ni,n #nd -#%i,n#nt n!o(%#- o$ t)! "!ntr#% n!r*o&! yt!-

LABORATORY WORK № 1#

GROSS SPECIMENS:

4? L!io-yo-# o$ &t!r&

2? Ot!o#r"o-# o$ $!-&r

9? Li(o-#

:? C#*!rno&! )!-#n,io-# o$ %i*!r

;? M!nin,io-# o$ br#in6? G%iob%#to-# o$ br#in

@? M!%#no-# o$ !y!



? M!t#t#i o$ -!%#no-# in %i*!r

? Fibro-#

MICROSLIDES

@4?#? C#*!rno&! )!-#n,io-#

;? L!io-yo-#

6? M!nin,io-#

40? N!&ri%!--o-#№ '1-A- CAVERNOUSE HEMANGIOMA.

T)! t&-or ti&! i "o-(o!d o$ ,r!#t n&-b!r t)in?'#%%!d *#"&%#r (#"! /"#*!rn di$$!r!nt

i! #nd $or- %in!d by !ndot)!%i#% "!%% T)! (#"! #r! (#rtition o$$ by *#rio& t)i"+ $ibro& %#y!r

T)! "#*!rn %&-!n i $i%%!d 'it) b%ood #nd t)ro-boti" -#! T)! t&-or &rro&nd!d by $ibro&

"#(&%!

4 V#"&%#r (#"! /"#*!rn

2 Fibro& %#y!r

№ %$- LEIOMYOMA.

T&-or i "o-(o!d o$ int!r%#"in, -oot)?-&"%! "!%% /t#in!d by (i"ro$&")in in y!%%o'?

,r!!ni) "o%or #nd "o%%#,!no& $#"i"%! /r&by T)! -&"%! #nd "o%%#,!no& $ib!r #r! di(o!d in

diord!r /ti&%#r #ty(i-4 -oot)?-&"%! "!%%

2 Fibro&! ti&! /"o%%#,!no& $#"i"%!

№ (- MENINGIOMA );i</= /

T)i (#tt!rn i ")#r#"t!ri!d by # "o-bin#tion o$ "!%% 'it) yn"yti#% #nd $ibrob%#ti" $!#t&r!

'it) "on(i"&o& ')or%!d (#tt!rn o$ t&-o&r "!%%. o$t!n #ro&nd "!ntr#% "#(i%%#ry?i!d b%ood *!!%

#nd $ibr! # t)! "on"!ntri" tr#ti$i"#tion ')i") )#*! r!"!i*!d t)! n#-! b&%bo& tr&"t&r!.

o-! o$ t)! ')or% "ont#in (#--o-# bodi! d&! to "#%"i$i"#tion o$ t)! "!ntr#% "or! o$ ')or%

4 B&%bo& tr&"t&r!

2 P#--o-# bodi!

№ 14&- NEURILEMMOMA.

T)! t&-o&r i "o-(o!d o$ $ibro"!%%&%#r b&nd%! $or-in, ')or%!d (#tt!rn T)!r! #r! #r!# o$

d!n! #nd "o-(#"t "!%%&%#rity (Antoni A pattern) #%t!rn#tin, 'it) %oo! #"!%%&%#r #r!# (Antoni B

pattern). Ar!# o$ Antoni A (#tt!rn )o' (#%i#d!d n&"%!i "#%%!d Verocay bodies. N!r*! $ibr! #r!

&&#%%y $o&nd tr!t")!d o*!r t)! "#(&%! b&t not 'it)in t)! t&-o&r

4 Ar!# o$ d!n! #nd "o-(#"t "!%%&%#rity

2 Loo! #"!%%&%#r #r!#

9 V!ro"#y bodi!

№ '1-A- CAVERNOUSE HEMANGIOMA.


-#,ni$i"#tion3

D!i,n#tion3

4 V#"&%#r (#"! /"#*!rn

2 Fibro& %#y!r



№ %$- LEIOMYOMA.

t#inin,3 Von? )ion

-#,ni$i"#tion3

D!i,n#tion3

4 -oot)?-&"%! "!%%

2 Fibro&! ti&! /"o%%#,!no& $#"i"%!

№ (- MENINGIOMA );i</= /


D!i,n#tion3

4 B&%bo& tr&"t&r!

2 P#--o-# bodi!

№ 14&- NEURILEMMOMA.


-#,ni$i"#tion3

D!i,n#tion3

4 Ar!# o$ d!n! #nd "o-(#"t "!%%&%#rity

2 Loo! #"!%%&%#r #r!#

9 V!ro"#y bodi!

i,n#t&r! o$ t!#")!r3 D#t!3



EDUCATIONAL-TARGET QUESTIONS ON THE THEME: TUMOURS OF THE BLOOD

SYSTEM.


4 To +no' "%#i$i"#tion o$ t&-o&r o$ b%ood yt!-

2 To +no' "%#i$i"#tion o$ %!&+o!. to ")#r#"t!ri! t)!-

9 To +no' -or()o%o,i"#% ")#n,! di$$!r!nt or,#n d&! to ")roni" #nd #"&t! %!&+o!

: To +no' "%#i$i"#tion o$ %y-()o-#LABORATORY WORK № 13

GROSS SPECIMENS:

4? (%!no-!,#%y d&! to ")roni" %!&+oi

2? P&?%i+! bon! -#rro'

9? Mor()o%o,i"#% ")#n,! in (%!!n d&! to %y-()o,r#n&%o-#toi

:? In"r!#!d %y-() nod! d&! to %y-()o,r#n&%o-#toi

;? E(i"#rdi&- )!-orr#,! d&! to %!&+oi

6? Fo"#% (n!&-oni#

MICROSLIDES

:? Li*!r C)roni" %y-()o%!&"oi /")roni" %y-()#ti" %!&+!-i#

4:4? Li*!r C)roni" -y!%oid %!&"oi92? Ly-()o,r#n&%o-#toi. /Hod,+in7 di!#!

№ &3 LIVER. CHRONIC LYMPHOLEUCOSIS )CHRONIC LYMPHATIC LEUKEMIA.

In %id! yo& "#n !! di$$&! in$i%tr#tion o$ %i*!r ti&! by &ndi$$!r!nti#t!d "!%% o$ -y!%o"yti"

ori,in In$i%tr#tion i it&#t!d bot) in (!ri()!ry #nd "!ntr#% (#rt o$ %ob&%!

D!i,n#tion3

4 In$i%tr#tion o$ %i*!r ti&! by &ndi$$!r!nti#t!d "!%%

№ 131 LIVER. CHRONIC MYELOID LEUCOSIS.

In %i*!r ti&! yo& "#n !! $o"#% in$i%tr#tion by &ndi$$!r!nti#t!d "!%% o$ %y-()oid ori,in T)!

$o"i )#*! ro&nd )#(! #nd di$$!r!nt i! #nd it&#t!d -#n%y in (!ri()!ry o$ %ob&%!

D!i,n#tion3

4 Fo"#% in$i%tr#tion by &ndi$$!r!nti#t!d "!%% o$ %y-()oid ori,in

#"- LYMPHOGRANULOMATOSIS, )HODGKIN>S DISEASE.

T)! tr&"t&r! o$ %y-()#ti" nod! i )#r(%y ")#n,!d Yo& "#n !! # %ot o$ ,i#nt "!%%? R!!d?

t!rnb!r, "!%% A%o. yo& "#n !! $ind -#ny %y-()o"yt!. !oino()i%! #nd $o"i o$ n!"roi

D!i,n#tion3

4 R!!d?t!rnb!r, "!%%

2 Eoino()i%!

9 Ly-()o"yt!

: Fo"i o$ n!"roi

№ &3 LIVER. CHRONIC LYMPHOLEUCOSIS )CHRONIC LYMPHATIC LEUKEMIA.t#inin,3 # )!-#to5y%in !oin

-#,ni$i"#tion3

D!i,n#tion3

4 In$i%tr#tion o$ %i*!r ti&! by &ndi$$!r!nti#t!d "!%%



№ 131 LIVER. CHRONIC MYELOID LEUCOSIS.


-#,ni$i"#tion3

D!i,n#tion3

4 Fo"#% in$i%tr#tion by &ndi$$!r!nti#t!d "!%% o$ %y-()oid ori,in

#"- LYMPHOGRANULOMATOSIS, )HODGKIN>S DISEASE.


-#,ni$i"#tion3

D!i,n#tion3

4 R!!d?t!rnb!r, "!%%

2 Eoino()i%!

9 Ly-()o"yt!

: Fo"i o$ n!"roi

i,n#t&r! o$ t!#")!r3 D#t!3



TABLE OF CONTENTS

L#bor#tory 'or+ 4 )ort )itory o$ (#t)o%o,i"#% #n#to-y M!t)od o$ in*!ti,#tion in (#t)o%o,i?

"#% #n#to-y:

L#bor#tory 'or+ 2 Nor-#% "!%% tr&"t&r! C!%% in=&ry Dytro()y! P#r!n")y-#to&! dytro()i!;

L#bor#tory 'or+ 9 Nor-#% tr&"t&r! #nd $&n"tion o$ "onn!"ti*! ti&! M!!n")y-#% /tro-#%?

*#"&%#r dytro()i!@L#bor#tory 'or+ : Mi5!d dytro()i!

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L#bor#tory 'or+ Prod&"ti*! in$%#-#tion Gr#n&%o-#to&!. 'it) (o%y( $or-#tion22

L#bor#tory 'or+ 44 Ad#(t#tion #nd "o-(!n#tion Ti&! r!(#ir Or,#ni#tion Hy(!rtro()y Hy?

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L#bor#tory 'or+ 42 T&-o&r G!n!r#% in$or-#tion E(it)!%i#%3 b!ni,n #nd -#%i,n#nt No-!n"%#?

t&r! #nd "%#i$i"#tion26

L#bor#tory 'or+ 49 T&-o&r E(it)!%i#% or,#no"(!"i$i" t&-o&r2L#bor#tory 'or+ 4: M!!n")i-#% n!o(%#- T&-o&r o$ CN M!%#no"it! n!o(%#-94

L#bor#tory 'or+ 4; T&-o&r o$ b%ood yt!-9:

Guide to Laboratory Practice Part

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