Gross neuroanatomy measures & introduction to variability References Steinmetz H., Furst, G.,...
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Transcript of Gross neuroanatomy measures & introduction to variability References Steinmetz H., Furst, G.,...
Gross neuroanatomy measures &introduction to variability
References
• Steinmetz H., Furst, G., Freund, H., “Cerebral Cortical Localization: application and validation of the proportional grid system in MR Imaging”, 1989, Journal of Computer Assisted Tomography, 13(1):10-19
• Ono M., Kubik S., Abernathey C.D., Atlas of the cerebral sulci, 1990, Thieme Verlag
Talairach transformation&
variability range of main sulci
Method• Tomographic images are collected on 30 hemispheres of 15 people
(22-63 yo)
• Talairach transformation is performed using 4 AC PC and 5 extreme landmarks
• Sulci are identified manually and projected sagitally
Align extreme pointsShift AC PC vertically and side-to-side
AC
PC AC
PC
Central Sulcus 20 hemispheres
Sylvian Fissure (R) 15 hemispheres
Sylvian Fissure (L) 15 hemispheres
Calossal, Parietooccipital, Marginal sulci, 30 hemispheres
Leftover variability after Talairach transformation
Summary
• Central sulcus (CS) in the postmortem Talairach brain is located 0.5-1.0 cm anterior to the CS in the 30 hemispheres studied here
• 2-3 cm displacement is observed in most of the studied major sulci
Incidence rates of main sulci
Method
• 25 postmortem brains
• Length determined by running a chord inside sulci
• Molded silicon models are developed to study internals of the sulci
Statistics
Statistics