gp130

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gp130 gp8 0 ß- actin p21 untreated treated treated 24

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gp130. gp80. p21. ß-actin. untreated treated treated 24 hr 48hr. - PowerPoint PPT Presentation

Transcript of gp130

Page 1: gp130

gp130

gp80

ß-actin

p21

untreated treated treated

24 hr 48hr

GP130 Heaters

GP130 Heaters

Bazedoxifene as a novel GP130 inhibitor for Colon Cancer ...Bazedoxifene was purchased from Acesys Pharmatech (USA), and oxaliplatin was purchased from LC Labora-tories (Woburn, MA,

Bazedoxifene as a novel GP130 inhibitor for Colon Cancer ...Bazedoxifene was purchased from Acesys Pharmatech (USA), and oxaliplatin was purchased from LC Labora-tories (Woburn, MA,

The Oct4 homologue PouV and Nanog regulate pluripotency …...lines and its overexpression is able to maintain mESC in an undifferentiated state, even in the absence of Lifr/gp130

The Oct4 homologue PouV and Nanog regulate pluripotency …...lines and its overexpression is able to maintain mESC in an undifferentiated state, even in the absence of Lifr/gp130

Discovery of a Novel Orally Active Small-Molecule gp130 ...mct.aacrjournals.org/content/molcanther/12/6/937.full.pdf · Chemical Therapeutics Discovery of a Novel Orally Active Small-Molecule

Discovery of a Novel Orally Active Small-Molecule gp130 ...mct.aacrjournals.org/content/molcanther/12/6/937.full.pdf · Chemical Therapeutics Discovery of a Novel Orally Active Small-Molecule

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Supplemental Figure 1. Hematoxylin and eosin (H&E ...df6sxcketz7bb.cloudfront.net/manuscripts/...Supplemental Figure . Analysis of gp130 and 9 Ikzf3 (Aiolos) expression in mixed BM

Supplemental Figure 1. Hematoxylin and eosin (H&E ...df6sxcketz7bb.cloudfront.net/manuscripts/...Supplemental Figure . Analysis of gp130 and 9 Ikzf3 (Aiolos) expression in mixed BM

Role of gp130 Activation for HSC Self-renewal Aurore Degrange and Lisa Treat BE.400 Term Project December 10, 2002.

Role of gp130 Activation for HSC Self-renewal Aurore Degrange and Lisa Treat BE.400 Term Project December 10, 2002.

Dimerization of the cytokine receptors gp130 and LIFR ... · cytokines that require receptor heterodimerization. Conversely, stable preformed heterodimers would discriminate against

Dimerization of the cytokine receptors gp130 and LIFR ... · cytokines that require receptor heterodimerization. Conversely, stable preformed heterodimers would discriminate against

Functional involvement of Daxx in gp130-mediated cell growth … · 2019-05-16 · located in the nucleus. Because previous studies have demonstrated that Daxx can bear both pro-

Functional involvement of Daxx in gp130-mediated cell growth … · 2019-05-16 · located in the nucleus. Because previous studies have demonstrated that Daxx can bear both pro-

Discovery of a Novel Orally Active Small-Molecule gp130 Inhibitor … · 2013. 3. 21. · Previously, we discovered novel quinoxalinhydrazides to have desirable physicochemical and

Discovery of a Novel Orally Active Small-Molecule gp130 Inhibitor … · 2013. 3. 21. · Previously, we discovered novel quinoxalinhydrazides to have desirable physicochemical and

An unusual cytokine:Ig-domain interaction revealed in the ... · LIF and related cytokines bind both gp130 and a second signaling receptor, such as LIFR or OSM receptor (OSMR), to

An unusual cytokine:Ig-domain interaction revealed in the ... · LIF and related cytokines bind both gp130 and a second signaling receptor, such as LIFR or OSM receptor (OSMR), to

Role of gp130 Activation for HSC Self-renewal

Role of gp130 Activation for HSC Self-renewal

Transcytosis of IL-11 and Apical Redirection of gp130 Is ... · motifs are present in the ICD of IL-11R1. The transcript variant IL-11R2 lacks the 32-amino-acid-residue-long cytoplasmic

Transcytosis of IL-11 and Apical Redirection of gp130 Is ... · motifs are present in the ICD of IL-11R1. The transcript variant IL-11R2 lacks the 32-amino-acid-residue-long cytoplasmic

Interleukin-6; Back to the Future Prof. Tadamitsu Kishimoto · SOCS-1 IL-6 gp130 IL-6R JAKs ... One year after treatment after treatment 41 Successful treatment of reactive arthritis

Interleukin-6; Back to the Future Prof. Tadamitsu Kishimoto · SOCS-1 IL-6 gp130 IL-6R JAKs ... One year after treatment after treatment 41 Successful treatment of reactive arthritis

Altered gp130 signalling ameliorates experimental colitis ... · Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived

Altered gp130 signalling ameliorates experimental colitis ... · Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived

Potential therapeutic implications of IL-6/IL …...Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer Tae-Hwe Heo1,2, Joseph Wahler2 and Nanjoo

Potential therapeutic implications of IL-6/IL …...Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer Tae-Hwe Heo1,2, Joseph Wahler2 and Nanjoo

Defective gp130-mediated Signal Transducer and Activator of ......2 Ian P. Wicks, David M. Tarlinton, 2 Ulrike Novak, 5 Joan K. Heath, 1 and Ashley R. Dunn 1 1 Ludwig Institute for

Defective gp130-mediated Signal Transducer and Activator of ......2 Ian P. Wicks, David M. Tarlinton, 2 Ulrike Novak, 5 Joan K. Heath, 1 and Ashley R. Dunn 1 1 Ludwig Institute for

CNTF/LIF/gp130 receptor complex signaling maintains a VZ ...growth factor-responsive ventricular zone (VZ) precursors in the ventral forebrain. Analysis of Lifr–/– mice suggests

CNTF/LIF/gp130 receptor complex signaling maintains a VZ ...growth factor-responsive ventricular zone (VZ) precursors in the ventral forebrain. Analysis of Lifr–/– mice suggests

Forced Homo- and Heterodimerization of All gp130-Type Receptor ...

Forced Homo- and Heterodimerization of All gp130-Type Receptor ...

“The Storyboard Method for Research Strategy and Management” · 3) Dimerization of gp130 activates the JAK/STAT pathway which activates a variety of . downstream effects. *There

“The Storyboard Method for Research Strategy and Management” · 3) Dimerization of gp130 activates the JAK/STAT pathway which activates a variety of . downstream effects. *There