Good morning

Bruce Rosen, chair of theBIRN Executive Committee

BIRN Executive Committee

• Mark Ellisman, BIRN CC and our host

• Arthur Toga, Mouse BIRN

• Steven Potkin, FBIRN

• Elaine Collier, NCRR

• Greg Farber, NCRR

Working together

Tuesday AM•Updates

Wednesday AM•Cross test bed working groups

Tuesday PM•Cross test bed working groups

Wednesday PM•Reports from working groups•3:15 p.m.

Integration: Working Groups Today

• IT Task Force

• Structure Function Integration

• Data Integration WG: Progress & Plans for BIRN Utilization

• Integration of Workflows with the Portal

• ROI in fMRI Data: Integration of Freesurfer with FIPS.

Integration: Working Groups Wednesday

• Prioritizing Workflows/Data Provenance: Utilization of Data and Recording of Data Provenance in Workflows

• Ontologies and Domain Scientists – BIRNLex Curation and a Neuroanatomy for Cross-Species Mapping

Integration: Working Groups Wednesday

• Ontologies in Data Integration: Using Ontologies to Transform Text Annotations into Knowledge Maps

• Integrated Image Distortion

Even More Fun!

• Portal Demo and Data Integration Tool sessions both days

• Posters available

• Guest Speaker – Thomas Murray, president and CEO of the Hastings Center

• Dinner tonight at the Great Hall at Eleanor Roosevelt College

Operations Committee - Charge

• Work directly with the Executive Committee.

• Make recommendations on strategic decisions and allocation of resources.

• Determine and prioritize cross-test bed infrastructure needs and challenges.

Operations Committee - Members

• Jeff Grethe

• Ilya Zaslavsky

• Phil Papadopoulous

• Jyl Boline

• Jessica Turner

• Karl Helmer

• Joe Ames

BIRN Mid-Course Correction

• Greg Farber

fBIRN – Clinical Working Group

• Mission: Design and implement the consortium protocol for the clinical data collection; integrate the other working group efforts with the clinical research.

• Aysenil Belger, UNC• Cindy Wible, BWH• Daniel Mathalon, Yale• Daniel O’Leary, IA• Gregory Brown, UCSD…….

fBIRN – Clinical Working Group (continued)

• John Lauriello, UNM• Judy Ford, Yale• Kelvin Lim, MN• Steven Potkin, UCI (Chair)• Adrian Preda, UCI• Tyrone Cannon, UCLA

fBIRN – Statistics Working Group

• Mission: To explore and apply a broad range of statistical methods on the FBIRN

imaging, behavioral, and clinical data.

• Bryon Mueller, MN• Doug Greve, MGH• Gary Glover, Stanford• Gregory McCarthy, Duke• Gregory Brown, UCSD (Co-Chair)• Hal Stern, UCI (Co-Chair)• Jessica Turner, UCI…..

fBIRN – Statistics Working Group (continued)

• Kelly Zou, BWH• Lee Friedman, UCI• Padhraic Smyth, UCI• Seyoung Kim, UCI• Sandy Wells, BWH• Steven Pieper, BWH• Randy Notestine, UCSD• Amanda Grethe, UCSD• Christine Fennema-Notestine, UCSD • Vince Calhoun (UNM)

fBIRN – Calibration Working Group

• Mission: Develop and test methods for reduction of intersite imaging variance.

• Bryon Mueller, MN• Doug Greve, MGH• Gary Glover, Stanford (Chair) • Jessica Turner, UCI• Lee Friedman, UCI• Norbert Schuff, UCSF• Xiaoping Zhu, UCSF• Randy Gollub, MGH• Tom Liu, UCSD

fBIRN – Cognitive Working Group

• Mission: Design, implement and validate cognitive tasks for use in consortium

protocols across sites.• Aysenil Belger, Duke• Cindy Wible, BWH• Daniel Mathalon, Yale• Daniel O’Leary, IA• George He, IA• Michele Diaz, Duke• Gregory Brown, UCSD….

fBIRN – Cognitive Working (continued)

• Gregory McCarthy, Yale (Chair)• Jessica Turner, UCI• Adrian Preda, UCI• Judy Ford, Yale• Dan Mathalon, Yale• Theo Van Erp, UCLA• James Voyvodic, Duke• Bryon Marion, Yale

fBIRN – Imaging Processing Pipeline Working Group

• Mission: To develop, implement, and test the initial FBIRN Image Processing

Pipeline for the production of standardized datasets for statistical methods

development.

• Doug Greve (Chair)• David Keator, UCI• Bryon Mueller, MN• Jeffrey Grethe, BIRN-CC….

fBIRN – Imaging Processing Pipeline Working Group (continued)

• Hyo Jong Lee, UCI• Lee Friedman, UCI• Syam Gadde, Duke • Randy Notestine, UCSD• Amanda Grethe, UCSD• Christine Fennema-Notestine, UCSD

fBIRN – Neuroinformatics Working Group

• Mission: To design, implement and test: the federated database for transparent storage and access of the FBIRN and other datasets; the software interfacing

with the SRB; the website interface for the database; the visualization and analysis

tools; etc. • Bryon Mueller, MN• Burak Ozyurt, UCSD• David Keator, UCI (Co-Chair)• Stephen Wong, BWH (Co-Chair)• Dingying Wei, UCI

fBIRN – Neuroinformatics Working Group

• Doug Greve, MGH• Jeffrey Grethe, BIRN-CC• Jeremy Bockholt, UNM• Mark Anderson, BWH• Hyo Jong Lee, UCI• Rashmi Chandrasekhar, UCLA• Karen Pease, IA• Hans Johnson, IA• Glenn Hoffman, MGH• Syam Gadde, Duke• Tiffany Elliott, Yale

Mouse BIRN – Atlasing Working Group

• This taskforce has interoperable atlasing as it's first priority.

• Ilya Zalavsky, UCSD (Chair)• Amarnath Gupta, UCSD• Jeff Grethe, UCSD• Seth Ruffins, CIT• Yoni Nissanov, Drexel• Bill Bug, Drexel• Carl Gustafson, Drexel…

Mouse BIRN – Atlasing Working Group (continued)

• Alexandra Badea, Duke• Jeff Brandenburg, Duke• Allan MacKenzie-Graham, UCLA• Erh-Fang Lee, UCLA• Heng Yuan, UCLA• Steve Anderson, UCLA• Queenie Ng, UCLA• David Shattuck, UCLA…

Mouse BIRN – Atlasing Working Group (continued)

• Jyl Boline, UCLA• Maryann Martone, UCSD• Josh Tran, UCSD• Willy Wong, UCSD• Asif Memon, UCSD• Zhaohui Sun, UTHSC

Mouse BIRN – Data Federation Working Group

• This group deals with issues of data integration and federation.

• Amarnath Gupta, UCSD• Jeff Grethe, UCSD• Vadim Askatokhov, UCSD• Edriss Merchant, CIT• Seth Ruffins, CIT• Bill Bug, Drexel (Chair)• Sally Gewalt, Duke• Alexandra Badea, Duke…

Mouse BIRN – Data Federation Working Group (continued)

• Jeff Brandenburg, Duke• Karen Crawford, UCLA• Allan Mackenzie-Graham, UCLA• Jyl Boline, UCLA• Maryann Martone, UCSD• Joy Sun, UCSD• Josh Tran, UCSD…

Mouse BIRN – Data Federation Working Group (continued)

• Willy Wong, UCSD• Diana Price, UCSD• Ted Manly, UTHSC• Hongqiang Li, UTHSC• Zhaohui Sun, UTHSC• Jintao Wang, UTHSC• Rob Williams, UTHSC

Mouse BIRN – IT Issues

• This group is involved in BIRN IT issues.

• Sonia Collazo, CIT

• Lucy Upchurch, Duke

• Rico Magsipoc, UCLA

• Mark James, UCSD

• Arthur Centeno, UTHSC

Mouse BIRN – Animal Models

• A cast of thousands (just kidding) is involved with measuring data on models

for Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, and a genetic

reference population that can be used as a mouse model of complex human

disorders.

Morph BIRN – IT Group

• This group works on the Morph BIRN data repository and on enabling testbed tools to

use BIRN CC infrastructure

• Nicole Aucoin, BWH• Brian Boyd, Duke• Vicka Corey, MGH• Katie Hayes, BWH• Glenn Hoffman, MGH • Cornelius Hojatkashani, UCLA• David Kennedy, MGH…

Morph BIRN – IT Group (continued)

• Anthony Kolasny, JHU

• Dan Marcus, WUSTL

• Mike Mendis, MGH

• Shawn Murphy, MGH

• Kevin Teich, MGH

Morph BIRN – Morphological and DTI Calibration Group

• The group identifies the sources of variability, reproducibility and metrics for

DTI data

• Silvester Czanner, MGH

• Jim Fallon, UCI

• Jonathan Farell, JHU

• Christine Fennema-Notestine, UCSD

• Anders Dale, UCSD…

Morph BIRN – Morphological and DTI Calibration Group (continued)

• Bruce Fischl, MGH• Amanda Grethe, UCSD• Randy Gollub, MGH• Karl Helmer, MGH• James MacFall, Duke• Susumu Mori, JHU• Allen Song, Duke• Stuart Wallace, MGH• Anastasia Yendiki, MGH

Morph BIRN – Machine Learning and Semantic Web Group

• Polina Golland, MIT

• Eric Grimson, MIT

• Tommi Jaakkola, MIT

• David Karger, MIT

Morph BIRN – Visualization

• Steve Pieper, BWH

• Ron Kikinis, BWH

BIRN CC – Leadership

• Mark Ellisman

• Phil Papadopoulos

• Jeffrey Grethe

• Mark James

• Ilya Zaslavsky

• Maryann Martone

• Amarnath Gupta

• Steven Peltier

BIRN CC – Core 1

• BIRN Operations and Community Support

• Vicky Rowley, Rocks Support• Kennon Kwok, Rocks Support• Bao Nguyen, Network Operations Center

Engineer• Tom Hutton, Network Operations Center

Engineer• Ryan Biltz, Systems Support• Daniel Wei, Database Support and

Applications…

BIRN CC – Core 1 (continued)

• BIRN Operations and Community Support

• Kimberly Hurtz, Data Grid Support and Applications

• Arcot Rajasekar, SRB Project Lead• Lucas Gilbert, SRB Jargon Developer• Skip Cynar, Technical Writing• Lee Hornbrook, Website• Ruth West, User Interface Design

BIRN CC – Core 2

• Maturing the BIRN Infrastructure

• Vicky Rowley, Systems Integration Lead• Kennon Kwok, Systems Integration

Engineer• Bao Nguyen, Network Operations Center

Engineer• Kimberly Hurtz, Data Grid Support and

Applications…

BIRN CC – Core 2 (continued)

• Maturing the BIRN Infrastructure

• Daniel Wei, Database Support and Applications

• Jana Nguyen, BIRN GAMA (authentication and credential management) developer

• Vadim Astakhov, Data Integration Applications

• Ramil Manansala, Portal Applications

BIRN CC – Core 3

• Data Modeling and Integration

• Vadim Astakhov, Data Integration Lead

• Brian Sanders, Application Developer

• Edward Ross, Data Integration Engineer and Application Developer

• David Little, Data Integration Engineer and Application Developer

BIRN CC – Core 4

• Translating Scientific Application Workflows

• Jason Novotny, BIRN Portal Lead/GridSphere Architect

• Ramil Manansala, Portal Developer• Lawrence Bohanan, Portal Developer• Jana Nguyen, BIRN GAMA (authentication

and credential management) developer• Tomas Molina, Portal Developer• Neil Jones, NA-MIC Grid Developer• Stephan Lamont, Parallel Registration

Algorithms

Other Groups

• Stuart Zola

• MITRE

• National Database for Autism Research/CIT

• NIH Program Staff

The Way Forward

• Now

– Develop tools that are useful

– Create, collect and share data that can enhance science

• Eye to the future

– Become useful to domains beyond neuroscience