Nl6kt( aI nr Arbtr B stbin ynrtine Favd'tiat

Going Bananas: The Futurefor Edible Vaccines

ho erer rhotrghl dd ve .ould vmci,ndeorchildrn agaiii a dnadeddnss by giviig rhem a brnoa1

vd l rd ry i sh ! t s . A lm0 ' .

a ibodies alair( a bade.ir dur causes di{.doea Aire. sug tbe n\ pohroes, rhe ni..pmdued anribodies agxiii rheplob inlbeirblmd 6 $rll $ in stretiors h their g$.some parbogens .ircular ii rbo blood vhile

Thc innunizalian

Itdlbeg.n rhen Dr Ch*l.s J. Anosn,rpldrnole.ulaLbiorqhrMq r noLher ieed abnof bouNrohd.hild o. r yisirbThaik|daid ir gor the vheds iuning "I .hough( thdiIse.o dfi .daLrly olpdring yd.in*inroedibhph s Nch as b.nanr rher bin8o, weblvc an el|edre sysem ol innu z.ion '

ThdNrsin lq9r Aidhelound a My

whiled tu Tcxm A&M IolirdeorBio$ic..es md T{b.olqy h tlouso[ DrAmte.i. along sirh.olleagls Hrgh Mhm.Pb D orlne lNitutc aid John Clenrnu,Ph D. olrhcTulane School ol Medtr ft ifNcv O .ds, insdeda ge.eforheFiiis Esdrft rnri8ei (HBsAg) ido robr.o phnhTie E.oqd ie.obbinant prctin hd I rcpq.rier sinilr ro rhe miigei der red ton hm.n

Follo\iigrb4 a c.h ol siemisb tronrhe RosNcll Pirk CatrH Innnub ir Buffalo,Nd! Yorl. in cotrjundLor Ri.h Texd A&M.round rbar ni.e ted rh gendiell) eryinercn pod.oss conhn'ng rhe hepriirn lr pro-ti dedopedrnribodieslgah$bcpdirisBItm Pobros,chmcds eid reft de Ptr

red te$ subicd. Vi.e E.dily ert rlrn

rnte t'ar children uillgo up if the parcntk arrs it only takes abnxa n lo do the job.

coi,q a,m,Acoihn!.d N! I PJSe

Fdr hmrns, you'd brve ro oqft e ahne lor mw Nuro4j lor .oolins rhemde{roys dtrldige . Vhich lerd5 us ro

Baa.r rE a ndunt !sbi.t. tor ar €dible vscile b<aN rhey a.e ofren dE t6rsolid lood given ro Thnd worrd drildrci, qbd&exp{td tobe the iiitid bcidi.i.nes oltheFsr.h Dness like dixrhoea, chok€and h.Fnis mc nkh moa prevddr ir rhc

A! Amr.' FioB our fiye nillior.hdftn di. tor dhrho* alone in rhes .otrrlns a.h ycmi iid aeordins ro rrie *nrldHcalrh oryxftdion, he|a[ s BjiLqsmorerhrn 300 Nllioi peoplc vorldpide, wirb chinl

Bri.ns a|so dor\ nred ro b. eldguded like bdayt va.cins do. rvhi.h n {hy rhispmi.ulrr rrrir is ed.ii3 lop billing.

De.li.abn to tue Pft.ertian ol Diserse Tlffitqh ne D.utop,'ent nnd DetlLery aJ vkcihe.

Melnick Paper Dr. joseph Melnick to Receiveon EnterovirusesAvailable From

Foundation

Wouldn't yauruthel

coi,J r,rd conturcd fion Prtvious P:se

$lile rhE developing counri6 m beitrgcyed tu!, gedically engiiercd plab ffililely to fi.d a dche ii the Unird Slires s{ell, No 'lodor likes to give shots. lndalnon cenainq rhe imunizdioi nre tor.hildtu u.ds rwo yeais old will go up it fiepeDr knovs it only hts r blmn. ro do rhe

Ol.otr^e, we caol rcally cdehnr unrilBh show llrat annbodi$ cD b€ prcduc€d iisulfici.it quaitity to Fovide prcreriveirnmity in people. Mice doil gst hepatitis B, nof do rrey gd .hc hndan fom or

Fofr ri.e, the nerr stcp {illrhe anribony in anin.ls rhat deio rhese dissmes, such ! piBs.

'"lhc fad $ar $ey go. ady immuneEspnn$ d rll iion giving n\en nibdalordly is sjgiili.dt," s{d Di JosephMeliick, a Pllfesor ol Vnobgy d

Melni.k h a boaid dem6d orAlbd B SrbinFonnddioi, . lomd s@iare ol .he lare DrSabii, dd a conrributoi h Va..rp l,tui,,. He!'u arso b ho 1996 ftcipienr ol rhc Atbed B.

ut a potato or abanana than lalee anitlkctian?

ce be pmd@d ii plmb ed rlrc prcducr i3 hedibl. lruit I rhink n 1ras a 6!ure. '

'Wo!ldn r you dr.\n cd z po ib or a

; ;;;k brdi rhr 6k h injrd tr, he 3 k€i.

Dt,Chu d AnEa t tad4! Prcsideht oi.lcEo dthe Bay. Thorapet rntitua Jat ptadRewrh, ,1e. nt Lhom, Ney Yo*, a rcnttalit .a,pannat dewted ta tlatu yhncesand qffiLiaed with ConelL UtiveEiu.

Sabin Gold Medalhe Albet B. Sabin Vrcine Foun&lod isplq€{ r0 moDcc !\ar Dr JNeph LMelnick, Disringtrhhed sflim ftotssr

at Blylor Cologe dfMedicinc, Division ofMol@uk Vnobsy. Iill bs awdded L\e lhirdAn rl Albefr B. Sibir Gold Med,l. DiMel.i.k Fill re.eive rhe medal d a cdmdy robe held I Cotd Spring Htrboi hbmro-y on

Dr Melnick rd a co@npoiry of DLAlbd Sabin snd hs ovd 50 y6 ol spqien@in vimlogy Harch. Iirhdionally €doqi torbh nork oi polionyefris, sine 1994 he hdsa€n a htsidst ol rhe U.S. Comissior otrPolio EEdietiotr. ItE ha tuthord more !h.ilmo pap€n in vimtogy ad n lhc ednor ofsev*aibmk. His re*book m nt dr.dt,tt mrirl4) hs b@n tuslded i.io a,lohlugugdld Ne by ftdical snrdenb ii denHt4dve .o0ntieq md dno$ 20 yeds rso hdalqdy 3o1d ov{ I Nllion opies in Enslidl

DL Melnick h oio of de ms oton quo!

Aqdd, de Eler.or RoevElr HmmiriesAM4 i\e r\laimmidd A{,rd f@m rle shb ofIsmd. rhc Gold Medd A*,rd ot rhe soudrAfri&n Polionyeliris Resaah Fomddion, strdrhc Bild*in Me&r turDslinguished sfli.e

BiylorColks€ olMed (me f,Horron [Dr

The ThreatWe Cannot Ignore

hose ol you vho wil! rate rhe line ro@lully iead this issE ol tmdr ltrio,will bE inpBsd wiL\ rhe innovaiive

aPPImhs $d m being deveroped o c€lercv veciis. Altcn{ive nqhods ol va..iieddieq (ag., tmgeni. plrnb) ed new .ombin ions ofexhung childrent vrccing tuorcw vays ro rca.h n@ people vho *ill beneft tm de levd ofpiotctiotr thd orly a ve

The key poiit io rcmenbu h dar tron' 'l6 ate s{efm ltE tMse! qlildiow dis?64a lans 6 kryenunb aJpea|ktMk rnrakd.d, io tutkt *ree th.t Ldz

Wirh L\e effi ol intmrriond ftvel'geogEphicar immunity no rong* otre6 usaDy madinCtul pmrec.iotr aBair$ rhs ravaga

Tht Sabin

Moieovei it is a dog@s rsivdc .o ssunc.ha AIDS oily ifl(ts enain goups While itis he rhd gay people aid Iv ddg u*s mmoE hequently str(td dua obe6 ir theUtritd SiaB, it i! equally hc rhar, thsughoutdre rcs of the woid, n is de hdeh*xud srEitrof AIDS rhlr predonindes. This h why rheSabii Foutr&tion h absolutoly comiGd todoing svdyrhing po$ible ro facilnat $e devel-opmnr or m etreciive Htv/ArDs v&cine

Tlte sraris.is m sraee@dg.the Sabin loondation .ommisioned a

ftdy rhet sotrght io c,rcukre rhe diHi dd

urired shb. nre resulrs ol $esbdy pEsnr a compelling eo.nomic css for dc ugon. iead ro

The catu rclotiry b thedittx teahent aJAtDs fat drD

ore tumtdtiull, h*het kan the

rtqnn?nJor dewk'pkE at dt

llfi)1 This d{isn. is svd doEnind bogsling wheo you m.sidu md mis Sl0 bilrio! ot r€tucnt @sts do iorinclude tbe co*s of @.iig HW vilhod AIDS,ntr dc ir iiclude dy indnet cosb (e.g.. Io$

This sononic inpmrive b@nd evdmoE pssusive whei yotr ftrlize $ai 6e fewdenpeutic dflss thd have bten devdo!€d .oftat AIDS. such N AZT and the prctseinhibitos. ac still uiprovd ro bE efedre inrh. longrm. Then co( ,so placs ftarme0t

Cleaily, all ol us orcalDe$eluilhunad and soioftic impmt ol infedious dis.** mun do eveqding in our pov{ ro ftakevecine developnenr dc *1 priorily for orcou ry. lve i..d ro rate his rhftat r sdously s rhe Defeise Deptuent dos itr rhe vaymd I @k io prcred us ton exrsnal eie

ER skptut4 chaiffi bJrL Roodalkeah2^

Fa tldaliol isabsolutely coflmittedto doing eoerythingpossible to facililstethe deaelopnent afan AIDS uaccine.

mies. The Sibin Foundatioi h6 asuned rle dship 6ld in wking io co0quq infe-tious disede. You suppon ol $s Fouid4iodores us m@iignrl hdp id fightiig $ismonl hd seial equivrlenr of rd.

Meetings Seek Consensus onDevelopment of AIDS Vaccine

f_or 'drroo is flc&d ro hrvc prligi.pded h I sns or mrerirgs rtrd

liir heltul r0 dcline ne" !ftrgies td rhedevcropft I ol xn HIv/AtDs v&ci.eThe fiar ol rh*e nrlrgs vrL hdd inltbmml ol rtrh yea d rb. NtH .imDus inBerhcdr. Marvlrd Tlt rollovinsfonrh. rb. sabii Fouid4io. spor;ed a

fsringhdd { cotd spn is Hrbor Lrbo[roRor rorg lrl,nd, Ne* Yo*: a.d ii APril, asyntoiun sFn\ord by dje Hda d AIDS!trurk w hdd d rhe tudi.or rJoN ilDedhrD, Ivra$$b rctrs. lvhik somewbar d ithrd'nt nd i0d agendi Egorloracb{s ro ednig. idal rnd oriiions so A ro sl! iiFdion lo. dD develoDne.r or i ctiahtc.

arh.NIH'neringotrFebn:o 1l t5.DL Adho0y F,uci. head or NtAlIr. indi.ftd'rr h\ leLleiitiofm U' M cilerhprarn f l r ' i i ! ,A r0 rded ! ,e ropn r t ro / r i lDsveone. Ackio{kdgins rtr 4 rhue rrc I ntavofude nftkd rord dDr inhibir rlie ierdopmer ol xvr.is.DrF.rielririons r goysrdHt, $Ddrt'.. aid i.durr), pznm^hip{rh v€.ifi. sortj !o b3 fd d drfir€n i|tsnvft dong he lar ro liceNins a edn. oodd ..1rnyinritL),impo$ibtetorenh,

iFgove unenr or itulNry atone ro

tudI phde r md ph6e 2!{.c'i. lnrl! otondrd4c !r

nsriig, bavc shoM dem ro b.

Unlotun{dy, bocrr rhc cotrs

lg.jrndrase) !re 0.NmM lor

sbblnhed ]ieur:lti.s ari.bodrs ro Hlv iidt ftd tjti rh*e

de'noilnkd bf rdomr rppmr

Aro d^.u$cd *rs rbe &k

vrcy ot rhe ifid vaidior of nV in devclop'ng ! rrccmc Mo$ vrcire caididfte\ rtrqLJ ' d \Le ro l rn r (L ] rn rd f tonsboo .

B. rhr \ r' ' ro nd n Nun, Anm.r mdw$kn Eutupe aod rrirn:rrd tror sb rleblo"d. Ho*"u!i90;6orHrvtitdjn;*nndwidc ir or tro. B subryp{, whi.h ae hnsnn.td bdqokiu,lty. Unkno{n is qhdher or ior. vr.ciJE *rll eti.ir n!$ rerdive imnuicBponss rtkr {ill be pDdrive rsliie xll subryps. FordisfdD., rctrv@iis{i|l i&dro.orii ora nixtuEotHtvsni6 Thepav.lenft ot hddossxurl hnsmnsior rtsorndsscoB rhe inpotur& of mros:l inn!my in Hlv rcdiotr Ne, vrcins eiu n€dditrdod loi mnlariotrs ind delivery slsems forrhs 'ndrdion ot ! m .osd ihmurc ft$om.

The n( v..ci.e ! egy.obe;ltuakdu0dn rtre ner gov.flnenr blueprin! * $rred4 rheNrHm*ri're, is expekd b&rbe'pnme booe" immiz4ionshedrtesing acftr[rox erpqion veror fo]toNed bv aiHr v i6o" ir boo$. Ncaori"liois ." u ni"*",\ i h l , J r t r M t re r Co f l dsh rmdCh mn3'!r . osbbti\hm tuom rorprorcLling

\,th, IA 1e que,tt1lt al

;'i,1 t luhether at nll dn

nlv ttl(ctne aa ld bpdeaeloperl, therc'p1nse was atlenthusiastic "yes."

FR sr..},la t4) oJ tht &,bil Foh(tdiot, \arb. Mmd s.rr tEh) rJ rE wfi.Dr Lrtiltk tls,i",." n n'1.*t' l'^a'.'d tl, *nl,;ll'"i

'ih pde brorgll rogedrr ii rbe ejlon ro rom! .oEarr lor Id.eedi'f in rhe dcydoDiealor m Hrv/AtDs rac.iN. .nd ro ddemi; h","rb. slbii Foridariotr .an asfr ii rhn daonD tlltu'ift Hillemn, Drd of drc N1erckhlir te for Theruptuf. R4urch. opeid rhehfttrn3 br protiosinq I hodd otyrmiNdevdopmen. .hd is a tird of goydinsrlhd t r rn rd dden j . rd j l qse i ! dd Lh?fo ' i d on tu ! i onAr 5 t r ! r "bdse i

fllite llouse SupportsSabin ̂ {IDS Er-ent

rcsidcnl and M^ Cri|roD mcIlororryChai'tol lh. Albedl]. S.binvtLrrine lbund ionGrl r Fu rdraiser ro b. he rd Thnndnv, Oorober

Comt^Dy, one of ihe lxne$ gbsing rsidonrial homcliuikling lims rn rbc .otrnr] \dih rerenues i| crcess.r$ll0 llion. Ms ThoDlson s corpant has b€trrespo.sibleforthe desi$ atut consrucrion otcon!n,ori al rn d rcs idcnr ixl ptupedies rtno€hotr r

c l l r o f r I r , , r dd tuon ,u \e^ r3dislinsn'shed euens rilt igailie. * thclcvc yHills illorel B.verlyHill\, icnlilornir br the evcnr. i

The locus ol rbe lGah n 1. genemie ftrnds lroaccelerarelro3,e$nr l

_ nn f i e |o i r lI o r ! dLo^

lnr rhe SrbinI f.unoarcn.

iI 'l l nohp$n

l chxrord,ci r-ohdxlion ardiChaj ro t0reI sdr!'i FoundarionlI wcncrnI Division.

ii;;.1::,'.;1: -.* i ApDird|: .;": ,:t i ih opis,.: : : " t . r

- , " , i lommlnnl krd.

- " , , i , ndkd , ' . } h 'r nr.mt\0tr scad

' : . ' .

. 1 i : ' " i . . - i nLnsds .h r n i;';'e:"i'r:. I ble oBanizaio ,

lnrchdin! rhsBoY' : t . , , l s , - t r ' . I A . . , 4 "; " ' " q .

l L h e L k , r \ i ) . i h eLa 6,..,, l onnBctrood

I Clildrens Foundarioni xnd rhe oED:cj Cou y P.rronringI Ars cen'e. shen aI r6ce ot 'ne

: : . ' , . . " . / ch d ns r ro 'pn i

r Uiivcrs iq o f CrljtotuirI ]rvine. Coltepc oI- iMedicinc ltr9e5 n,.

by PesiddrClnron to dre Bord olc Fcdcial Naliond I,lo.lgage

; ; ; : " , " , " , " , ;rccognizins her rork on behauoldrc Sabnrvrc in. ForndxiioD, i lor.ptutn oryuizxrioi dedic .d ro rlrc rirvc iu oldi$rs. tlrrough irnDUn zr.rion Ms.Thompsoi is fie PEldcnr .nd CbiclErecurirc oftl.d ot the l<dhryn G. Thompson

President Replies to Sabin Foundation Ietter

A \ i h e h d e r . l l h e n . e $ o r d , l u L h 1 , e ltrn!!eom.d!n ry ro ni,\c

lh lerving iod.y lor l4mes Lx Coqrette,Fmnce. io altcnd The lntenatioml Collfcren e On llreH isto.y ol Vacciiologr The higlJiehr of $is con fe.cnce vill feature ihe sibh FoL ndarion\ tsenrarionol.ommemo rirr scroil! 10 Da.€ll S. rand HeloisrSahin,nrE..gnirionofihelrlesavingso ofD(.Jon* Srlk and Albe( Sabh in conquei ing polio sonethitr y4s ago. Thi\ cerernony rill Mib rne trvj

'f;i#+i-li;

orsly compehtive sclcmif.lic*o dsolrrs Sall mdj srbi,,, ushcdns in a ner

THE SECONT)MILLENNIUI{,

I M' prcsidc(j ou children ddi srandchild.enj desFrotety nc.d

your lcade^hip

'+t'As fohder or the j

.dionararb.iR sabjn Ivxccine roudario., he.d jquererod in r_ew Camrn, Iconnecricui.I would hkc ro It*. rhis opponudry ro high

T'-^- wwlll bc able ro enjol riresdn Nillnor be inremtrdby I monn.r ii.m "h ch m one can hide

H"( r[.,,liShr rhe fted to .lramrii.ally nrclc$c rhe fiDrcialrGorces allocared io rhe dcvolophenr ol d efi{iiveHIV/AIDSvx.cine Yotr nut be arvafe lnat only $l25nillion ! mere 39, .. ol drc NaLionrl l.litutc olHalln s bu'lCct for IIDS r!.tn.h is Jedicrted 10 klcr. dcrclopfunl. A'd rei, a\ has rreen I rcven !!rdd asdn, innuniTrrioD js the mosr cffl.icnr aid cosrerli{iire wit to coIlqnft lnal diseaes.

f"^rl

rur, roie.igo'goii! lonmnt. on dd.oo Lnrrgoi..nnrs Hr nokd rr.r.iro, IrodrNrirr ber irkrign.rdrn.nddlilrkd hnro rdirft lotrrgei !{,t'

th!.eedfoi h,!d!rrlrdr dd.r.t

1 L,er \rr qF€naa $d i! id rg flr brsi. .ri

tcd bl rrrc goromtrr, rr rnr tur!&rl'rri.th ind de'eritnr I df ri Hlv rr.i:.nl' r- r'nu{ ! ritrG nd .r d sl

F.mdnionrub.lp tmriLl. rnd* hr

A r$dlclPrnr JiLr rLi rticsrbior.(iihlion.ouLd L,r.irinrrlirr i)ttuaE Irlrri*r ororg: I tutonrrd pubtr.Nt.I T0d €, k.k of idf-(.nd rdro-.y ir rlir rldel0tn orri Hr\ Ym r rfstirn|eEdcfons Lo n idun,l rrniy$ D.mil tolr Hlv rr.nic nrL bjgeE fu rlrtolghriu-h.. ( prbLL. poliq d,!$s b.foE rdsitiNshrdNlloDr I hr I-_!u ddL.n.o, rd bry::iqii.i..( inPxd \, iDniigpfdtrlifuricsr ol rhe(oi.uic.ors Lo Lheilor irirbslo'ldrrrhc{ d.fir n nd coi

.e0 0i rrr[HlV i edi.i tr { rfiru] r! r prrln,lrfgturpor l]rof i nN &dehL*rd rr

nniN 0rurv\onrlriLle{odiru u|brnt.r.\'rll I b! rri\k. rf-nlL!rr.hillFl

'lhe big-q-r oDodunit\ ro. ft

lb rbe q6h0i .f rtulLd or .orm Hrv u- r..orLd bc ielrto d.rlr,slu$NrA rnerlrm 6ric "J$."

rrdtr4r rs \rcd l.s rnxio, Lro\re!c(rbou r!\ r mr!brberco'i0tLrlli.

Ih. d's ntrdiilr !dLGdn.Ly\kish.d iirptdd rtul Ehlr r si' rl!!.Ihrr to Ark rL,e:{iLfbilnyor{i HlvrAlDS {N.rir Ll]r inr{*blc

. \lt ntrnnrd].srrlr3Li:brliryr rtg!io drLnrnlnesrrrji.tiihiliidus

. nt iaL Iin,l rariy: \rrJ s Lrrtr*r p.ide rid 0LibLi! ior-i.irnr Hlvfklt\tud Grelop0rfrrdiliri.!,: \{ sluL td tuodrt drn don orp{ r.rtsi\ ir mJrdsetopnar

D, Hot t (dttttl i)ith'| 'nitt)4

n u\t tt t\ht) t h \.rt Pltlv a

. I0,podr r, tr! trrLL iuer. r{ruus 0l!r..trfqr,.$ li.iDg Ir.Io Lls]! d rLre

. A !LrirrLlr'. Ne rkd ror Ll'r pfbti. toud..!rid rbr rli rr.1]e for r dtre lierh$ Ir{tiL,g rl'.dncfc dd oore ir 0c\rdirg irsr rui ri!i \riLh rL. m! olu.aGdir.

fh[ nrt: rr d Nt r)d1lt rturnfiar.l:b Attd B S.[i)\rnh Fan! i.r

!r.. \|u.d:: poLL.]' rd!o.|I '

Irllr llriliid ^l)S ln\rird.

s|.ifi !r oli:nlisend.!isi \ricdntr rn:dd r 0i ro tr \.i! iJi.r{e\. drrr ofrlrrl.br. fttrrrrLldrl,!|oirir r 0.gdnftiiiil

uk i.ro rfhn.! rh s ir d!dcr.q, rSroird ]\rfdres dno\rlI gt.l L]{ m. ] .f ]fu .r nnnc

ILmJ sr Ls:Bl rlr. Ef nNi,lor muLr. rddtrr rr'r irnrar

i L r y i r i i . r i r t s n rL b3 r r ro ra l

D. \mM?d!-

News Update

The Gamble Programby Gilbeft M. Schiff,M.D.

-flh€ chn{Ho p u li.!O r

I (CHLVk) tr s!, ib hed

ohiD l hrd rbe tanu.f ofb-on.'n! Di@.or ol CHIMR i. 19?4.ad subsq, ed\ 0t rEsidenr olGII{Rin 1934 h Odobtr 1995.r rmsref olssct xlieneilbdtr.ci CDIR md the childritHo\pibr Medicrr ccdf (cllMc)rslrdii rh! sr$li:hment olrhc cnmble llocmr vidri. dEDnisio. or rifediou5 DnQs6 dCHN{C SiriNsrigdodbd.

sf-ific vleii* hrye induded flbdlr, r€ns.otriips. rnnkna ( rqcrivdcd lid hc drnnrrn), he,!d tt Ns I .rd 2 ihlnus &eltulrpflru$s. ird ie* .onbi.xrioN oi .rrirdhood vic.

Wc hde ben iLxhrflul ir obhirin8rre0$s for nbdh, obclla.nshrmmp\, ddinntreua wciis Itr ddirion, {e l[ve D!Er!ngh6 ro . rcrrfls vadie, ard hlvu ptayed Indor role m dr evrrunior ora 6hin\ ya.. ie [bi.h will b. li.ensd by J]iuary I, 197.

ln rhe .er l2 nodrls' sc vilL iiilirrdd/or mdire diiilrl o{luarion dudies or rlo€lly{dmiinortd rotoiDs iD youB childrsl| anemdnid*erpph'nfl rd i'rnenh uai0ebrsded for rdulB, a mr.onjlgdei p| nocdcus veciic fo. rhe eheny, Ive choho $c.cins md r hel!?i sinple{ v&cii. We villrr$ be r prdi.ipdifg <iu ror r mrlri sireelalmlotr of. live, dbnutd, intrr.A,liifluuia ladne. md rclltrh Fo$is w.

A.rivid dng M h hd iidudedeui!xrioi or igcds for iifrena, $e conmoi cold,h!ry* d'sder. lnd ednoviru$s. Tbese it iieshre i.vohed mtud lnd orp.nnsd vn?l

Oq rhe yem d,e GIN{R lid dE GlnblePtolnn hiw be. well tutrdcd Ctrdenr tundiog induds 4 NIH VTEU (Vrd.e THhdrnd Evddion U.it).ontrd, ai MH ori Rlm'n nodd.ontrdi r{t Nnctus indrry

Gnb M. strif, M.D Dnrto,atcanbte

Dnn iu aJ trlldbr\ bL454, t:itiidi orb

$tponi'g$atrol30uiddnJ diEdionnovedro ios md rtmoneled ofrn* ft crrNtc.

The missior of.hc Gdnble Plogrh i\ ro,€nua hmai $ff.nrg b) .onimriis molsrldliddiiilalrtsdchren rirgnftep fldrior

Adivries oldr Ca i'ble Piogiln induderbe develoFfl! !trd clalMrion oldirpnod.*sys, !a.und, md rntrvi'rl dngs: $ncilhieor viml md brcErjrl d(s; dcdopnsn( olk{ea i nprovld vrci delifry sy$emsr ud.!ue.ion.bou ! dnnM5 vni.e uq $dtldmsLutu ro lali pmnrd ol,.rdncdicil.omorunid* nr sEff biJ b.ei, xid rdnrinEsro bc, erirc N nemb€^ ol dri$ry Broup! .othe gdrmnem (bo$ nfte md fedcml). i u!ry,ad mdeu. ftrr6, and A ofll.ed dl mlionrllrmrasio Bl oto,tjriod. \\t ft also iNirdnom d'.c ro rinc ro be lecrF^ to. n oial andmtmdionrl meetngsi ad I ro oft.n alldup.r d r sFk€:penor for bidmedi.d rs&h.o f utul .gui!i.r .id rh: Lr S Co'sris

AEtb 01 Ertuch lnr rhe co$I. Porinhar Lnduded rclpi'iiory disas {iinr sa.Relpir dory syi.yr al vnN {h. comflon ord,pidfro.oQlpo.uio a)idLmned d rsfl(rorrins, bdedrl), hepft ! A, A. C. Di heQsr al dns$s (si,id.x. !tri&lL,.yromestLldyinL! hea* 6)i nsri d rr* (rb€rlr, m$dd. 5rh disede)r rd efcolrdr d rs4Id penssn (q,,oopiis .ou,eh).

vrcci E Gaidr hs inldlnd rlioic.v mdoisinaLl.ge gDrps{ifinhroerddryl

D, s,rin xdti?: hdtin r'6lte oJ cdilknaH. \th! L t{t.to \o,rt n!d\ nl cht.trcr'

Vaccine Research In The Newseone EFNh lm beci nrlins denews ft.endy eilh two inpotul sbdres bemg mounaq oE conptered lnd

wo* noP $s 30lqs aBo, sd b{tuse deynay possibly leld h rhe imunizdior ol chil

ResdhdsdB rihdre VetEm AtraisMedic, Cenbr, NIH, oid C# w$remResne Univenirt have demnslrftd rhat rhe

Bumet of Ausrrlia dd Peb B. Mallw oltuieir shmd $E Nobel piE lor resdchvhich foudd thd the imme sysh ol new-boms vas bo ilmrrE b Ejed fotrigD ori-gens. th. coiclusioi ieached by Bumt $dMedawm hs ben a ftid.denbl in biolosy for

Tre Ent wo& publbh.n in S.t uft,cHes a new utrd.$rmdidg df the imme systn. Tte B.l.imore ren, led by Mddhsaom lckc, inoculded 2-day old ni.e wimlo* doss or vids. dd loodd rh{ the ditrrzlsdevelop.d longrem inmunig/ ro ths die^e.Ho*ever ni.e exp.$d to la€e dos oI rhesm yins, she said, wrc umble ro moun it

rheolhdrobegin$issun0* IrBo$on,rheNsv Eigldd Medicoi C€nar hs ftlo&d tulit wiu be pdicipating ii a nationwide pogdnro evdude a rumor va.ciiE ifunded for pleveidns acuren@s of advded $n canH'nt study will involvs abou( 100 medicrl fttrrd bd ov* 300 patieit in a five yer pmgmto detuine ir the va@inc will be ndR efl{rivE and hrve fe*d side etr@6 rhdn inra'fnon,$e cmnt chone for liedDe .

PEliminlry Br rcsul6 of rhe vm.inej'lesignatd N GMl have b@i pomisins Nhenu*d ro combar ldvo.ed nelbom, *hichstiles some 15,m0 Am.dcaN ach yer mdesulh in trbout 3,000 dorh amrilly. $e veode onsish orr synrhsizd vsnioi of d iusafound on mel$om! tumor @lls, conbined Nidrt pmrein round ii snails and $e brk of a SourhAmdca fte ued ii lho nl}iig offtor h*rnd. Tne puqose ol rhc veciie n b boo$ thepahenrs imuneje{ons again$ nelanofr. .

To be .oisidftd for dE pmgrm. parieNmu$ have advm.en nehhti. nelmomrwhichha bM @rd w n sugery. Forsu.hqdidlB, lbe odds ol lons h sBivd arcpoor th ciisri4 rhdapy Tlredskolrurftre h high (50 ro 309i), and only ab.ut 2s96of thore {bo sutrft a ft.ufti.e m afve aturfive yeds. For the study, hall of the pdien6*illbe Eeared virh irdretun aidha *nh rhe

'n'e GM2 melaiora vaeine my evenbilly be round efl{lvc agdi$ othd cmce6 6

studiu arc especiallyThese paiicular

noloblebeca se they

scientists xoha xaol1 lheNabel Pize t'ot theitzuorkmore thar 3Aye s ag0,

dispute the '

coficlusions af

imuDe Esponse rnd qui.*ty died. I sho$,SMti ldsoe onclude4 rhar'llvetr .he cd.r@r '10$, newboms ca rspond like aduls."

BafitrM t4: r'.db MN. tMbelmkq h.]p prtuhturl

Ind!4eidEfl ftsmh by me rm riNIH !.d Cme Waren hrd iinilfi cmclusion!. Prul v L.bmi, qho led the CaeWe{em shd, said rbe frdings my be teyro developirg drogs lor onroltidg &Ltitisard diabds, ad r.y help in devdopiryvaEins ,geinrr conpler vidss, socb a

EDIToRIALBo,\RD

.An Invitation to Becorne aMembee'in the Sabin Society

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SABIN FoUNDATIoN

dn.iIiHy tonnDi.{ion bds,en rttrs. iuiifiq indtr{i.1. oLi p ublic c.i!. mikc .!nc!'d viLh b. dedqjrnu[ mdNorvmi$ thr prblnlEd prc&.drnPr!r bdc nN'ngs vil ds n p$]ic ud |.1.r r. a$.ier Dd [ui r{ss in dqrlilyiosopponu.rri.s md pnontes lnr ac&b mdGk o|nui, dd in fofrNhi.s enli-Phr.flrd potr.i$ ror redoctopm4'r rltLr

. R{rdi.totlt td ttt[) hrttn||ntll! c(nptar t'tihriar h th' tjtu titrtritotat\ tvlnth the hnnnl lt.oiat al01Abxt t. \rbi) L.t1tlft \ ta \itl h.dnratun tlc.lxri R stuin catd Mltt!. Dytop lttrr!tutr k)i.|'t rtu!rnti,i

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