Glycogenolysis

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Carbohydrate metabolism GLYCOENOLYSIS

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conversion of glycogen into glucose and its regulation

Transcript of Glycogenolysis

Page 1: Glycogenolysis

Carbohydrate metabolism

GLYCOENOLYSIS

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GLYCOENOLYSIS

• Break down of glycogen into glucose• It takes place in liver ad muscles• Key enzyme is glycogen phosphorylase

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Reactions

• Shortening of chains• Removal of branches• Glucose-1-phosphate to G-6-Phosphate

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Other pathway

• Lysosomal degradation(alpha amylosis)• Gemma-amylosis

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Regulation

• Activation of Phosphorylase• Activation of inhibitor-1• Role of calcium in glycogenolysis in muscles

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Glucose metabolism Processes –Glycolysis –Glycogenolysis –Gluconeogenesis Substrate level regulation Hormone level regulation.

Glucose metabolism Processes –Glycolysis –Glycogenolysis –Gluconeogenesis Substrate level regulation Hormone level regulation.

Gluconeogenesis and glycogenolysis

Gluconeogenesis and glycogenolysis

GLYCOGENOLYSIS€¦ · reversal of glycogenesis. overview of glycogenolysis step 1 step 2 step 3 debranching enzyme glucan transfera se activity glycosida se activity bifunctional

GLYCOGENOLYSIS€¦ · reversal of glycogenesis. overview of glycogenolysis step 1 step 2 step 3 debranching enzyme glucan transfera se activity glycosida se activity bifunctional

Glycogenolysis, Glycolysis and Lactaterrobergs/426Lect9Glycol.pdf · Glycogenolysis, Glycolysis and Lactate cAMP epinephrine Ca+2 muscle contraction 1 3 2 4 5 6. Dr. Robergs Fall,

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Cell biology of carbohydrate metabolism. Glucose Glucose 6-phosphate Glycogen synthesis Glycogenolysis Glucokinase/ Hexokinase G6Pase Glycolysis Gluconeogenesis.

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CHOICE BASED CREDIT SYSTEM B.Sc.(Hons.) … · Pentose phosphate pathway and its significance, Gluconeogenesis, Glycogenolysis and glycogen synthesis. TCA cycle, Electron …

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Where on the diagram would the following take place? 1. glycogenesis 2. gluconeogenesis 3. glycogenolysis Now explain each term. glycogenesis gluconeogenesis.

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Digestion and absorption of dietary carbohydrates Pathways of glucose metabolism: glycolysis Pentose phosphate shunt Gluconeogenesis Glycogenolysis, glycogenesis.

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GLYCOGENOLYSIS AND GLYCOGENdm5migu4zj3pb.cloudfront.net/manuscripts/101000/101088/JCI3910108… · POSTMORTEM HEPATIC GLYCOGENOLYSIS IN HYPERINSULINISM ... By adding 1 per cent conjugated

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Hepatic Glycogenolysis

Hepatic Glycogenolysis

Glycogenolysis Basic

Glycogenolysis Basic

Epinephrine Administration by the EMT Administration For...•Antagonizes histamine •Increases glycogenolysis and raises blood glucose levels •Raises heart rate, blood pressure

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Measurements of Gluconeogenesis and Glycogenolysis: A ...€¦ · Glycogenolysis: A Methodological Review Diabetes 2015;64:3996–4010 | DOI: 10.2337/db15-0640 Gluconeogenesis is

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Glycogenolysis/glycolysis. Dietary sources of glucose Varied –Fruits, vegetables, cereals, grains All sources of dietary carbohydrate –Converted to glucose.

Glycogenolysis/glycolysis. Dietary sources of glucose Varied –Fruits, vegetables, cereals, grains All sources of dietary carbohydrate –Converted to glucose.

S y n dromes Journal of Genetic Syndromes & Gene Therapy...Gluconeogenesis; Glycogenolysis ... An overview of glucose physiology Glucose is the principal substrate for energy metabolism

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Carbohydrate ism Gluconeogenesis,Glycogenolysis

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Desensitization Glycogenolysis Ca2+-mobilizing Hormones … · 2014-01-30 · drugs often leads to a blunted response when the tissue is subsequently exposed to the agonist. This

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Respiratory chain and oxidative phosphorylation + Glycogenesis and Glycogenolysis 1.

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A New Insight for Muscle in Blood Glucose HomeostasisBlood glucose homeostasis between meals is maintained by endogenous glucose production via glycogenolysis and gluconeogenesis.

A New Insight for Muscle in Blood Glucose HomeostasisBlood glucose homeostasis between meals is maintained by endogenous glucose production via glycogenolysis and gluconeogenesis.

1 glycogenolysis

1 glycogenolysis