Glucose

Key Concepts of Glucose Monitoring and the AlphaTRAK® Blood Glucose

Monitoring System

ALPHA-347/R1 January 2010 ©2010 Abbott Laboratories

Canine/Feline Diabetic Cases

• There are an estimated 1.43 million diabetic dogs and cats in the U.S.

• 600,000 (43%) diabetic patients are undiagnosed• 270,000 (19%) are diagnosed, but untreated

43%

38%

19%

Undiagnosed

Diagnosed/Treated

Diagnosed/Untreated


Data Sources: Populations – Pet Food institute, 2005. Incidence and Treatment – IMS, 2003 and2005 and from Humane Society website: WWW.hsus.org

Untreated Diabetes

• Untreated diabetes can lead to other serious diseases:– Ketoacidosis– Neuropathy (nerve damage)– Increased incidence of infections (i.e. Urinary

Tract Infections)– Cataracts (dogs)– Gastrointestinal dysfunction


Early treatment can help a pet live a healthier life.

Early detection can be accomplished by:

Understanding the symptoms e.g., Excessive urination, drinking, hunger Weight lossUnderstanding and actively looking for the risk factors e.g.,AgeObesityInactivityGenetics


Early detection can be accomplished by:

Understand and look for co-morbidities

According to Veterinary Pet Insurance (VPI), the top ten medical claims are:


Dogs

• #1 Ear infections

• #2 Skin Allergies

• #3 Psyoderma/Hot Spots

• #4 Gastritis / vomiting

• #5 Entertis/Diarreha

• #6 Urinary Tract Infection

• #7 Benign Skin Tumors

• #8 Eye Inflammation

• #9 Osteoarthritis

• #10 Hypothyroidism

Cats

#1 Urinary Tract Infection

#2 Gastritis / vomiting

#3 Chronic Renal Failure

#4 Enteritis/Diarrhea

#5 Diabetes

#6 Skin Allergies

#7 Colitis/Constipation

#8 Ear Infections

#9 Respiratory Infections

#10 Hyperthyroidism

Managing Diabetes


• Managing and treating diabetes occurs with:

– Diet

– Exercise

– Insulin Regulation

– Monitoring


Key Factors in Managing Diabetes

“Our goal is that when we’re treating pets with insulin, we want to keep their glucose levels down to a point where their clinical signs are going into remission.”

Dr. David Bruyette, DVM, DACVIM

Importance of Blood Glucose Monitoring

• Monitoring is the process of tracking the patient’s glucose level over time:

– Helps to assess the effectiveness of prescribed treatment

– Assists in enabling changes to optimize treatment– Helps balances the appropriate level of insulin

necessary


Blood Glucose Curve

Importance of Home Blood Glucose Monitoring

“Achieving good control of blood glucose levels quickly is key to preventing negative side effects associated with diabetes. This rapidity of control can only be achieved through the use of injectable insulin and at home blood glucose monitoring.” Dr. Sara Ford, DVM, DACVIM


• Home monitoring of blood glucose levels can make a positive difference in a treatment plan by: – Reducing the affects of “white coat” syndrome (e.g.

hyperglycemia)

– Obtaining readings in a pet’s natural environment (e.g., more accurate)

– Achieving readings more frequently than possible in-clinic

The AlphaTRAK® System provides unique benefits to you and your patients

AlphaTRAK® Blood Glucose Monitoring System


Accuracy

Proven results equivalent to those from a reference method, the “gold standard”


“We have found that the AlphaTRAK® Meter was more accurate in determining blood glucose levels in dog and cats than portable human meters.”1

Dr. Elizabeth Cozzi, Ph.D.1-Data on specific meters on file

Validated for Veterinary Patients

• Human blood is different than dog or cat blood

• The AlphaTRAK® meter is calibrated and validated for cats and dogs

1 Mackay EM. The Distribution of Glucose in Human Blood (From the Scripps Metabolic Clinic). J Biological Chem. May 1932:685-8.

2 Coldman MF and Good W. The distribution of sodium, potassium and glucose in the blood of some mammals. Comp Biochem Physiol. April 1967;21(1) 201-6.


Now Validated for Glucose Monitoring in Horses and Ferrets

• The hand-held meter is easy for use in the field or in-clinic

• The AlphaTRAK® Meter provides accurate results in just seconds


Expanded Testing Range

• Now provides validated numeric readings up to 750 mg/dL in cats

and dogs

“This is a significant improvement because many newly-diagnosed and unregulated cats have glucose values above 500 mg/dl. Being able to better quantify the glucose level in the upper range will significantly improve patient diagnosis and our resulting treatment plan.”

Dr. Gary D. Norsworthy, DVM, DABVP


Easy to Use


• Obtain an accurate blood glucose result in

four simple steps …

Small Sample Size

• Small Sample Size –– Requires only 0.3µL of

blood without the need for a needle and syringe

• Speed –– Gives you accurate

numeric readings in seconds


AlphaTRAK® Blood Glucose Monitoring System

Look to the AlphaTRAK® Meter for:• Accurate results• Specific species blood glucose readings• An expanded testing range• Readings within seconds


To learn more about Abbott Animal Health, our dedication to animal health excellence and our quality products, contact your

local Abbott sales representative or Customer Service at 888-299-7416 or visit www.abbottanimalhealth.com


Glucose

Education

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