GLIOBLASTOMA BY THE NUMBERS 032919 kp
1
GLIOBLASTOMA AT-A-GLANCE GLIOBLASTOMA MULTIFORME (GBM), A TYPE OF CENTRAL NERVOUS SYSTEM CANCER, IS THE MOST COMMON AND MOST AGGRESSIVE FORM OF PRIMARY BRAIN CANCER. CEREBRUM HYPOTHALAMUS PITUITARY LATERAL VENTRICLE PINEAL GLAND 3RD VENTRICLE 4TH VENTRICLE BRAIN STEM SPINAL CORD CEREBELLUM MEDIAN AGE SOURCE: NCI SEER U.S. 2011-2015 SOURCE: GLOBOCAN 2018 58 65 AT DIAGNOSIS AT DEATH GLOBALLY, OVER 241,000 PEOPLE DIE EACH YEAR AS A RESULT OF BRAIN OR NERVOUS SYSTEM CANCER, WITH GBM BEING THE MOST COMMON FORM OF THE DISEASE ESTIMATED NUMBERS OF ANNUAL NEW BRAIN AND NERVOUS SYSTEM CANCER CASES IN KEY MARKETS GBM IS GENERALLY FOUND IN THE CEREBRAL HEMISPHERES OF THE BRAIN, BUT CAN BE FOUND ANYWHERE IN THE BRAIN. BRAIN AND NERVOUS SYSTEM CANCERS GLOBALLY 1-YEAR 2-YEAR 3-YEAR 4-YEAR 5-YEAR 20–44 AGE 45–54 AGE 55–64 AGE 35% 13.7% 8% 5.8% 4.7% 19% 8% 5% COMMON BRAIN CANCER RISK FACTORS FAMILY HISTORY SIGNS & SYMPTOMS HEADACHE BLURRED VISION BALANCE PROBLEMS SEIZURES NAUSEA VOMITING DROWSINESS WEAKNESS ON ONE SIDE OF THE BODY MEMORY AND/OR SPEECH DIFFICULTIES THE SIGNS AND SYMPTOMS OF GBM CAN VARY DEPENDING ON THE SIZE AND LOCATION OF THE TUMOR IN THE BRAIN. THE FOLLOWING ARE COMMON SYMPTOMS: RADIATION EXPOSURE SOME GENETICALLY INHERITED SYNDROMES MALE GENDER ADULTS AGES 45-65 POTENTIAL & AVAILABLE TREATMENT OPTIONS SURGERY RADIATION THERAPY CHEMOTHERAPY IMMUNOTHERAPY TARGETED THERAPY TREATMENT OPTIONS FOR GBM VARY DEPENDING ON A NUMBER OF FACTORS—TUMOR SIZE, POSITION, WHETHER IT HAS SPREAD TO OTHER REGIONS OF THE BRAIN AND THE OVERALL HEALTH OF THE PATIENT. SEVERAL TYPES OF TREATMENT MAY BE CONSIDERED BY A HEALTH PROFESSIONAL TO TREAT THIS TYPE OF CANCER, INCLUDING: GBM RELATIVE SURVIVAL RATES GBM SURVIVAL RATES BY AGE GROUP © 2019 Bristol-Myers Squibb Company AFRICA: 17,000 ASIA: 156,000 EUROPE: 64,600 NORTH AMERICA: 27,000 SOUTH AMERICA: 22, 900
Transcript of GLIOBLASTOMA BY THE NUMBERS 032919 kp
GLIOBLASTOMA AT-A-GLANCEGLIOBLASTOMA MULTIFORME (GBM), A TYPE OF CENTRAL NERVOUS SYSTEM CANCER, IS THE
MOST COMMON AND MOST AGGRESSIVE FORM OF PRIMARY BRAIN CANCER.
CEREBRUM
HYPOTHALAMUS
PITUITARY
LATERAL VENTRICLE
PINEALGLAND
3RD VENTRICLE
4TH VENTRICLE
BRAIN STEM
SPINAL CORD
CEREBELLUM
MEDIAN AGE
SOURCE: NCI SEER U.S. 2011-2015
SOURCE: GLOBOCAN 2018
58 65AT DIAGNOSIS AT DEATH
GLOBALLY, OVER 241 ,000 PEOPLE DIE EACH
YEAR AS A RESULT OF BRAIN OR NERVOUS
SYSTEM CANCER, WITH GBM BEING THE
MOST COMMON FORM OF THE DISEASE
ESTIMATED NUMBERS OF ANNUAL NEW BRAIN AND NERVOUS SYSTEM CANCER CASES IN KEY MARKETS
GBM IS GENERALLY FOUND IN THE CEREBRAL HEMISPHERES OF THE BRAIN, BUT CAN BE FOUND ANYWHERE IN THE BRAIN.
BRAIN AND NERVOUS SYSTEM CANCERS GLOBALLY
1-YEAR 2-YEAR 3-YEAR 4-YEAR 5-YEAR
20–44AGE
45–54AGE
55–64AGE
35% 13.7% 8% 5.8% 4.7%
19% 8% 5%
COMMON BRAIN CANCER RISK FACTORS
FAMILYHISTORY
SIGNS & SYMPTOMS HEADACHEBLURRED VISIONBALANCE PROBLEMSSEIZURESNAUSEAVOMITINGDROWSINESSWEAKNESS ON ONE SIDE OF THE BODYMEMORY AND/OR SPEECH DIFFICULTIES
THE SIGNS AND SYMPTOMS OF GBM CAN VARY DEPENDING ON THE SIZE AND LOCATION OF THE TUMOR IN THE BRAIN. THE FOLLOWING ARE COMMON SYMPTOMS:
RADIATION EXPOSURE
SOMEGENETICALLY
INHERITED SYNDROMES
MALE GENDER
ADULTS AGES45-65
POTENTIAL & AVAILABLE TREATMENT OPTIONS
SURGERY RADIATIONTHERAPY
CHEMOTHERAPY IMMUNOTHERAPYTARGETEDTHERAPY
TREATMENT OPTIONS FOR GBM VARY DEPENDING ON A NUMBER OF FACTORS—TUMOR SIZE, POSITION, WHETHER IT HAS SPREAD TO OTHER REGIONS OF THE BRAIN AND THE OVERALL HEALTH OF THE PATIENT. SEVERAL TYPES OF TREATMENT MAY BE CONSIDERED BY A HEALTH PROFESSIONAL TO TREAT THIS TYPE OF CANCER, INCLUDING:
GBM RELATIVE SURVIVAL RATES
GBM SURVIVAL RATES BY AGE GROUP
© 2019 Bristol-Myers Squibb Company
AFRICA: 17,000
ASIA: 156,000
EUROPE: 64,600
NORTH AMERICA: 27,000
SOUTH AMERICA: 22, 900
