Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are...

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Transcript of Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are...

Page 1: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

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Page 2: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

GivesomeexamplesofSoundsineverydaylife.-Speech-Ultrasoundmachineusedtobreakupkidneystonesordestroytumors-Ultrasoundpregnancy-feelasonicboom

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Page 3: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

::WhentheboundaryofaWavearefixed,therewillbeatransmiDedwave,aswellasareflectedwave.WhenthesetwowavesinterferewithoneanotherTheygiverisetowhatisknownasastandingwave.TheycanalsobethoughtofasawavewhichoscillateswithrespecttoGme,yethasapeakamplitudethatdoesnotmoveinspace::Nodes

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Page 4: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

!::WhentheboundaryofaWavearexfixed,therewillbeatransmiDedwave,aswellasareflectedwave.WhenthesetwowavesinterferewithoneanotherThueygiverisetowhatisknownasastandingwave.TheycanalsobethoughtofasawavewhichoscillateswithrespecttoGmxe,yethasapeakamplitudethatdoesnotmoveinspaceu::NodesItiswellknownthatobjects,allthingsbeingequal,willmovefrom;anareaofhighpressuretolowpressure.::wellthat’sessenGallywhatisthecoreofacousGcallevaGaGon.;Varyingtheshapeofthetransducervoltagewaveformhadasignificanteffectonlayerthickneuss,withasquarewaveformcreaGnguthinner,moredisGnctlauyersthanasinewaveformduetosteeperpressuregradientsatthenodes.AcousGclevitaGonisaphenomenxonwherebypressuuredifferexncesofstaGxonarysoundwavescanbeusedtosuspendsxmallobjectsingasesorfluidssuchasairorwater

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Page 5: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

AninteresGngautobiographicalnote:Idon’tknowaboutanyoneelse,asforme,InotoriouslyhadadifficultGmevisualizingstandingwaves.

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Page 6: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

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Page 7: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

::WhentheboundaryofaWavearefixed,therewillbeatransmiDedwave,aswellasareflectedwave.WhenthesetwowavesinterferewithoneanotherTheygiverisetowhatisknownasastandingwave.TheycanalsobethoughtofasawavewhichoscillateswithrespecttoGme,yethasapeakamplitudethatdoesnotmoveinspace::Nodes

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Page 8: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

Cytoskeleton:essenGallyaGssuethatconnectsacomplexnetworkoflinkingproteinfilaments,itbringstomindtheimagewhatmostofusarefamiliarwith.CulturesofCellsobviouslyextractedfromthesubject.Thentheusersendsalow-frequencysoundwavethroughthefluid,attherespecGveacousGcallevitaGonfrequency(250kHz,andoncethecellsarelevitatedintoastableposiGon,anotherultrasonicwavecanbeemiDed,andessenGallyan“ultrasound”canbetaken,wellyoumayask,welljermaine,howisthisimportant.Wellitwouldallowustostudythecellsinanenvironmentmoresimilartooneinvivo(onethatwouldtakeplacewithintheorganism),alsodifferentdensiGesreacttoultrasounddifferently,whatgroupofcellsUltrasonicsignalsfromtheseculturescanbeproblemaGcduetotheinterferenceofreflecGonsfromtheculture-platewell.Thecellstructureisalsoo`endeformedfromitsnaGvestateduetoadhesiontothecultureplate.

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Page 9: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

Humanembryonickidneycells(HEK)

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Page 10: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

Achievingdiametersbetween9-15microns

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Page 11: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

::WhentheboundaryofaWavearefixed,therewillbeatransmiDedwave,aswellasareflectedwave.WhenthesetwowavesinterferewithoneanotherTheygiverisetowhatisknownasastandingwave.TheycanalsobethoughtofasawavewhichoscillateswithrespecttoGme,yethasapeakamplitudethatdoesnotmoveinspace::Nodes

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Page 12: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

A`ertheacousGclevitatorisadjustedtoaproperstate,weuGlizeatweezercarefullytointroducetheanimalsintothelevitaGonposiGon.Figure1showsthelevitaGonprocessofanant,aladybug,andayoungfishinair.SincethelongitudinalcomponentoftheacousGcradiaGonforceFzismuchlargerthanthelateralcomponentsFr,theseanimalsareusuallylevitatedwiththelargestcrosssecGonoftheirbodiesperpendiculartothereflector-emiDeraxis,soastostabilizetheirposture.Theantisusuallylevitatedwithapostureasifitis“crawling”intheairFig.1a.SomeGmes,itstruggledtoescapefromtheconstraintofacousGcradiaGonforcebyrapidlyflexingitslegsFig.1b.However,itfailedbecauseitslegscanobtainliDlecounterforcefromtheair.ThepostureofthelevitatedladybugissimilartothatwhenitstandsorcrawlsonthegroundFig.1c.WecanalsoplacetheladybugintothelevitaGonposiGonwithitsbackdownwardandbellyupward.Inthiscase,theladybugcanhardlyturnitsbodyoverbyitself.Liketheant,theladybugaDemptedtoescapefromthelevitaGonforcetoo.It

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PhysicistsattheArgonneNaGonalLaboratoryareusingsoundwavestolevitateindividualdropletsofsoluGoncontainingpharmaceuGcalstoimprovedrugdevelopment.Drugsfallinto2categories:Amorphousandcrystalline.Amorphousdrugsaremoreefficientlyabsorbedbythebodythantheircrystallinecousinsduetotheirhighersolubilitywhichimpliesthatalowerdosecanbeused.WhensoluGonareevaporatedinavessel,theyaremuchmorelikelytosolidifyinacrystallineform.Thustopreventthisfromhappening,thesoluGonneedtobeevaporatedwithouttouchinganysurfaces.ThisiswhereAcousGclevitaGoncomesin.AcousGclevitaGonisusedtoevaporatesoluGonswithoutallowingthemtocrystallize.

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Page 20: Give some examples of Sounds in everyday life. · Physicists at the Argonne Naonal Laboratory are using sound waves to levitate individual droplets of soluGon containing pharmaceuGcals

thisismoreofabonusfeaturethantheactualpresentaGon,butIdon’twanttonotgivecredit.

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