Get to know OTIS. (Drugs, Pregnancy, and Lactation).
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Transcript of Get to know OTIS. (Drugs, Pregnancy, and Lactation).
Get to know OTIS. (Drugs, Pregnancy, and Lactation).
BRIGGS is pharmacist clinical specialist, Women's
Hospital, Long Beach Memorial Medical Center; clinical professor of
pharmacy, University of California, San Francisco; and adjunct professor
of pharmacy; University of Southern California, Los Angeles. Health care professionals are free touse
them as educational material for their patients.
Topics covered include caffeine, chickenpox, cocaine,
cytomegalovirus, diabetes, toxoplasmosis, echinacea, fifth disease, hair
treatments, hyperthermia, influenza vaccine, listeriosis, maternal
phenylketonuria, St. Some responses are
made in person or in a letter sent to the caller's health care
practitioner.
Because of the networking system, OTIS has the ability to quickly
call upon their entire organization and outside specialists in
government and private industry anywhere in the world to assist in
formulating a zofran settlement chicago attorney response to almost any inquiry.
OTIS also produces fact sheets for patients that discuss the fetal
effects of pregnancy exposure to a variety of drugs, environmental
chemicals, and diseases. He is a
member of OTIS and a coauthor of the reference book "Drugs in
Pregnancy and Lactation."
COPYRIGHT 2002 International Medical News Group
No portion of this article can be reproduced without the express written permission from thecopyright holder.
Copyright 2002 Gale, Cengage Learning. This method
involves detailed physical examinations by dysmorphologists
(pediatricians with special training in the recognition of birth
defects) of newborns born to women enrolled in studies as subjects and
controls.
The research results produced by OTIS members provides a rich
source of information for all of us who counsel pregnant women.
The following are some TIS studies currently underway, with
telephone numbers to call to enroll subjects in the studies.
* The Asthma Medication and Pregnancy Project on the use of asthma
medications during pregnancy, 888-523-4847.
* The Rheumatoid Arthritis and Pregnancy Study, which has a special
interest in the effects of leflunomide (Arava) on the fetus, but will
enroll any pregnant woman with the disease, regardless of whether she is
on drug therapy 877-311-8972.
* A study on the fetal effects of exposure to ondansetron (Zofran),
800-436-8477.
* A study funded by the Centers for Disease Control and Prevention on why pregnancies continue tooccur in women taking the teratogenic
acne drug isotretinoin (Accutane), 866-626-6847, the OTIS national
referral line.
Individual memberships in OTIS are also available to people with
training or a special interest in teratology.
GERALD G. These centers prospectively collect data on
pregnancy exposures of interest and actively follow up exposed
pregnancies.
The studies use matched controls--women who have called the TIS for
information on exposures known to be nonteratogenic. Allhttp://www.pdr.net/drug-summary/zofran-injection?druglabelid=243 rights reserved.
. John's wort, and paternal exposure.
While the primary function of a TIS is to provide accurate
information regarding pregnancy exposures, research is also an important
component of many centers. Some studies also
use controls matched for the disease.
Studies conducted in the past by OTIS members include the effects
of maternal exposure to ACE inhibitors, sumatriptan, cisapride,
clarithromycin, fluoroquinolones, psychotropic drugs, and varicella
infection.
Recently, members of OTIS's Research Committee detailed a
unique research method that will be used to conduct post-marketing
surveillance for teratogenicity of specific medications. Counselors can calm the fears of
expectant mothers when an exposure involves a nonteratogen and are
compassionate and helpful when the exposure is a known, potent human
teratogen.
Most counselors are familiar with a wide range of related subjects,
including teratology, dysmorphology, toxicology, and pharmacology.
Every year, the TISs receive approximately 75,000 inquiries
regarding pregnancy exposures from health professionals and the public.
Most inquires are made and answered by telephone. Every
geographic region of North America is served by a TIS; most are
affiliated with a university, university hospital, or state health
department. To find a TIS in your area, contact OTIS at 866-626-6847 or
go to their Web site, www.otispregnancy.org.
Each TIS has a staff of one or more counselors, directed by a
teratologist, who provide counseling and risk assessment regarding
potential teratogenic exposures. These fact sheets are available on the OTIS Web
site and from individual TISs.
Many physicians are unfamiliar with the Organization of Teratology
Information Services (OTIS), a group that provides practical information
to health care providers and their patients concerning exposure to
various drugs, chemicals, and other agents in pregnancy.
OTIS is composed of more than 35 Teratology Information Services
(TISs) and individual members in the United States and Canada