GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA...

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GENETICS

Transcript of GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA...

Page 1: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

GENETICS

Page 2: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

IT’S ALL IN YOUR GENES

When you were formed, you inherited

DNA from your father and mother in the

form of chromosomes.

You inherited 23 chromosomes from

your mother and 23 chromosomes from

your father.

You have 46 chromosomes in all.

Page 3: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

GENES

Chromosomes contain genes.

Genes give your cells the instructions for

cell processes.

Genes decide what traits you will exhibit.

Alleles are different copies of genes that

you can inherit from your parents.

Page 4: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

GREGOR MENDEL MOVIE

Page 5: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DEFINITIONS

DNA – deoxyribonucleic acid, nucleic acid that contains genetic instructions

Genes – DNA sequences that code for different proteins

Allele – a copy of a gene

Chromosomes – bundles of DNA that make up your genome, where genes are located

Genome – all of the DNA you contain

Dominant allele – an allele whose phenotype is expressed in

homozygous and heterozygous form

Recessive allele – allele whose phenotype is only expressed in homozygous form

Page 6: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DEFINITIONS

Genome - all of the DNA you contain

Dominant allele – allele whose phenotype

is expressed in homozygous and

heterozygous form

Recessive allele – allele whose phenotype

is only expressed in the homozygous form

Page 7: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DEFINITIONS

Genotype – genetic constitution of an individual, the types of genes and alleles found in an individual

Phenotype – trait, or observable characteristic in an individual that is based on his/her genetic makeup

Page 8: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DEFINITIONS

Punnett Square – a tool used by

scientists to predict phenotypes of

organisms based on allele combinations

Page 9: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DEFINITIONS

Heterozygous – exhibiting two (2)

different copies of a gene

Homozygous – exhibiting two (2)

identical copies of a gene

Page 10: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DEFINITIONS

Diploid cell – cell that contains two (2)

copies of each chromosome

Haploid cell – cell containing only one

copy of each chromosome

Gamete – haploid sex cell

Page 11: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Page 12: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PROBLEM 1:

Determine if the following genotypes are homozygous or heterozygous:

BB = _____________________

Bb = _____________________

Bb = _____________________

Page 13: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PROBLEM 2:

Using the Punnett Square above, determine

the phenotypes (colors) for each of the

following genotypes.

BB = ______________________

Bb = ______________________

Bb = ______________________

Page 14: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PROBLEM 3:

What is the probability that you will get a

white flower when heterozygous pea

plants cross?

How do you determine probability?

Do you remember the formula for

determining the probability of an event?

Page 15: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PROBLEM 3

P(event)= number of favorable outcomes

total number of possible outcomes

White flower: __________

Purple flower: __________

Page 16: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

Problem 4:

Imagine that you are crossing a

heterozygous plant (Bb) with a homozygous

recessive plant (bb).

Predict the types of offspring that can occur

by filling in the blanks in the Punnett Square.

Page 17: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Page 18: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PROBLEM 5:

Imagine that you are crossing a

heterozygous plant (Bb) with a

homozygous dominant plant (BB).

Predict the types of offspring that can

occur by filling in the blanks in the

Punnett Square.

Page 19: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Page 20: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

Problem 6:

Make up your own parental genotypes

for the pea plants and determine what

types of offspring they will have.

Fill in the blanks in the Punnett Square.

Page 21: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Page 22: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

NOW LET’S INVESTIGATE!

YOU WILL LEARN ABOUT YOUR

GENES AND THOSE OF YOUR

CLASSMATES BASED ON YOUR

PHENOTYPES.

Page 23: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PHENOTYPES

What is a phenotype?

A phenotype is a trait, or observable

characteristic in an individual that is

based on his/her genetic makeup.

Page 24: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

1st Phenotype:

“The Rolling Tongue”

This trait is dominant and will appear if

you are homozygous dominant (TT) or

heterozygous (Tt).

Page 25: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

This Punnett Square shows that both parents are heterozygous.

Page 26: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PROBABILITY

What is the probability that their offspring will be able to roll their tongues?

Write the probability as a fraction.________

Change the fraction to a percent.______

Page 27: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

MAKING PREDICTIONS

Let’s assume that both of your parents

are heterozygous. Make predictions

based on the information the Punnett

Square gives you.

We will determine the percentage of

students in your class that should be

able to roll their tongues.

Page 28: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

TONGUE ROLLERS

Predict the percent of Tongue Rollers in

the class. They will be a (TT or Tt).

What percent did you predict?______

Page 29: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

TAKE A SURVEY

Now let’s do an experiment.

Survey your class. How many students

are there in your class?__________

How many of these students can roll

their tongues?___________

Page 30: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

ACTUAL VS. PREDICTED

PERCENT

What is the actual percent of tongue

rollers in the class?____________

How does this percent compare with the

predicted percent?________

Page 31: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

THE CHINESE POPULATION

Our classroom is a sample of the entire Chinese population.

Based on the numbers we found in our class, we can predict the number of Chinese people who are tongue rollers.

Page 32: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

Predict How Many Chinese People

Are Tongue Rollers.

Statistical records from July, 2008, show

that the population of China is

1,330,044,544 people.

Can you figure our mathematically how

many Chinese people can roll their

tongues?

Yes! Let’s see how.

Page 33: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PROPORTIONS

Make a prediction using a proportion.

Tongue Rollers in Class = Tongue Rollers in China

Total Students in Class Total population in China

How many tongue rollers do you predict

there are in China?

Page 34: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

2nd PHENOTYPE:

ATTACHED EARLOBES

This trait is recessive and will only show

up if you are homozygous recessive

(ee).

Page 35: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

This Punnett Square shows that both parents are heterozygous.

Page 36: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

ATTACHED EARLOBES

Assume that both of your parents are

heterozygous.

Use the information the Punnett Square

gives you.

What is the percentage of people in your

class who should have attached

earlobes?

Page 37: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

TAKE A SURVEY

Survey your class. How many students

are there?_______

How many students have attached

earlobes?_______

What is the actual percentage of

students in your class with attached

earlobes?______

Page 38: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

MAKE A PREDICTION

Our classroom is a sample of the whole

Chinese population.

Predict the number of Chinese people

with attached earlobes.

Use 1,330,044,544 as the population of

China.

Page 39: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PREDICTION

Use a proportion to determine the

amount of people in China with attached

earlobes.

How many Chinese people do you

predict have attached earlobes?

Page 40: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

3rd PHENOTYPE:

INTERLOCKING FINGERS

Fold your hands together by interlocking

your fingers. Which thumb is on top?

Page 41: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Page 42: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DETERMINE

THE DOMINANT TRAIT

Can you determine which trait is

dominant and which trait is recessive?

We have two (2) traits, right thumb on

top and left thumb on top.

Page 43: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

TAKE A SURVEY

Survey your class. How many students

are there in your class?___

How many students have right thumb on

top?_____

How many students have left thumb on

top?_____

Page 44: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

USE YOUR MATH!

What percent of the class has right

thumb on top?____

What percent has left thumb on

top?_____

Page 45: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DETERMINE THE DOMINANT

TRAIT

Based on the percents you found in your

class, which trait do you think is

dominant?_______

Which trait is recessive?_______

Page 46: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

WHICH TRAIT IS DOMINANT?

Assume that all of your parents are

heterozygous for the trait (Ii).

Determine which trait is dominant.

If the _______ thumb is on top, you are

dominant (____,____).

If the _______ thumb is on top, you are

recessive (____,____).

Page 47: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

DID YOU FIGURE IT OUT?

The actual dominant trait

is________

Page 48: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

4th PHENOTYPE:

PTC STRIP TASTE TESTER

Some people can taste a chemical

called: Phenylthiourea-

Phenylthiocarbamide (PTC), and others

cannot.

Page 49: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PTC STRIP TASTE TESTER

Based on how many of your classmates can taste this chemical, determine whether the ability to taste PTC strips is a dominant or recessive trait.

Use a capital P and a lowercase p to construct your own Punnett Square for PTC taste.

Page 50: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PTC STRIP TASTE TESTER

If we assume that all parents are

heterozygous for the ability to taste PTC,

what is the dominant trait?

What is the recessive trait?

PTC STRIP TASTE TESTER

Page 51: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Page 52: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

MAKE A PREDICTION

Predict the percentage of Chinese

people who should be able to taste PTC

based on the number of your classmates

that can taste PTC.____________

Page 53: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

MAKE A PREDICTION

We can make this prediction using a

Proportion.

PTC tasters in class = PTC tasters in China

Students in class Population in China

Page 54: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

5th PHENOTYPE: THE WIDOW’S

PEAK

Now let’s look at hairline.

If your hair has a downward V shape, you possess at least one dominant allele (W).

Draw a Punnett Square to illustrate what would happen if one of your parents was homozygous dominant (WW) and the other parent was homozygous recessive (ww).

Page 55: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Page 56: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

MAKE A PREDICTION

Assume that all Chinese people have

one parent who is homozygous dominant

(WW) and one parent who is

homozygous recessive (ww).

Predict the percentage of Chinese

people who would have a widow’s peak.

Page 57: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

MAKE A PREDICTION

We can make this prediction using a

proportion.

Widow’s Peaks in class = Widow’s Peaks in China

# of students in class # of people in China

Page 58: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE

Draw a Punnett Square to illustrate what

would happen if one of your parents was

heterozygous (Ww) for this allele, and

one of your parents was homozygous

recessive (ww).

What results did you find?

Page 59: GENETICS - montclair.edu€¦ · IT’S ALL IN YOUR GENES When you were formed, you inherited DNA from your father and mother in the form of chromosomes. You inherited 23 chromosomes

PUNNETT SQUARE