Taxonomy of the genus Ropeamussin. Kairugaku Zasshi (Japanes Jour. Malacology)
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FFaaccuullttyy ooff MMeeddiicciinnee AAiinn SShhaammss UUnniivveerrssiittyy
PPoossttggrraadduuaattee SSttuuddiieess
Diploma in Parasitology
اتــــدبلوم الطفيلي
Program Code: PAR900
Program Guide and
Logbook
2
C a n d i d a t e C u r r i c u l u m v i t a e
[Name]
Please attach your
recent photo
photo here.
[telephone No]
[mobile No]
[mailing address]
[email address]
[postcode]
Experience
[Organization]
[your present job title]
[start date]
[location]
[responsibilities]
[Organization]
[previous job title]
[start and end date]
[location]
[responsibilities]
3
Education
[certificates]
[start and end date]
[school or college]
Training
[any other training that will be useful in your job]
4
Filled by post graduate authorities
Date of Registration
First semester _______________________
Second semester _______________________
Third semester _______________________
Fourth semester _______________________
5
TABLE OF CONTENTS:
Page
I – Welcome Statement 7
II - Mission Statement 7
III – Senior supervisor and affiliated departments and Hospitals 7
IV – Program specifications 7
A) Basic Information 7
B) Professional Information 8
1. Program Aim 8
2. Intended Learning outcomes 8
3. Academic standards 10
4. Curriculum structure and contents 10
5. Program courses: 11
6. Program admission requirements 12
7. Regulation for progression and program completion 12
8. Assessment Schedule and Weighing of Assessments 13
Course specification for Microbiology and Immunology 15
a - Basic information 15
b - Professional information 15
Course specification for Biochemistry 19
a - Basic information 19
b - Professional information 19
Course specification for Public Health 23
a - Basic information 23
b - Professional information 23
Course specification for Parasitology 26
a - Basic information 26
b - Professional information 26
Course specification for Molecular Biology 41
a - Basic information 41
b - Professional information 41
Course specification for Immunology 45
a - Basic information 45
b - Professional information 45
Course specification for Vector Biology 48
a - Basic information 48
b - Professional information 48
Course specification for Biostatistics 52
a - Basic information 52
b - Professional information 52
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V - General information 55
VI – Your log book 55
1 - Introduction 55
2 - Supervisors 56
3 - Tables for training records 56
4 – Log book preview 73
VII - Head of department approval for the exam entry 73
Detachable forms:
VIII – Thesis follow up 74
IX - Evaluation forms 75
7
I. Welcome Statement:
The Department of Parasitology welcomes you to the Diploma in
Parasitology. As a department we are committed to medical student education and
continuously strive to improve your educational experience.
This handbook presents information guide and logbook activity of the Diploma in
Parasitology administered by the Parasitology department, Faculty of Medicine,
Ain Shams University.
II. Mission Statement:
The mission of the Faculty of Medicine, Ain Shams University is
“Preparation of a trained physician, researcher and life long tutor capable of
following standards of medical care and ethics, with managerial and technical
skills in his specialty. Furthermore, promotion outstanding programs of health
care to serve the society, environmental development and targeted scientific
research for continual improvement of health”.
The mission of this degree is to prepare trained Parasitologists who have
detailed knowledge and understanding of the biology, life cycles, pathogenesis,
clinical manifestations, immune response, and basic and advanced diagnosis of
parasitic infections in humans and their relevance for human health. The
graduates of this program should also be able to work with other health authorities
to prevent and control the parasitic infection in the society.
III. Senior Supervisor and Affiliated Departments and Hospitals
Senior Supervisor
Prof.
-------------------------------
-------------------------------
-------------------------------
E-mail:
Affiliated Departments and Hospitals
-------------------------------
-------------------------------
-------------------------------
IV – Program Specifications
A- Basic Information
1. Program title: Master of Science in Parasitology
2. Program type: Single Double Multiple
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3. Faculty: Faculty of Medicine, Ain Shams University
4. Departments: Parasitology Department
5. Assistant coordinator
Prof. Dr.
6. Coordinator
Prof. Dr.
Head of the Parasitology Department
7. Last date of program approval: July 2009
B- Professional Information:
1. Program aims:
a) Providing broad-based knowledge and understanding of Medical
Parasitology including Helminthology, Malacology, Protozoology and
Medical Entomology.
b) Providing practical skills and experience in the laboratory diagnosis of
parasitic infections.
c) Providing the candidates with the basics of microbiology and
immunology.
d) Providing the students with basics of protein and nucleic acids structure,
functions and manipulations.
e) Providing knowledge and understanding in research methodology and
ethics, epidemiology, study planning, and data reporting, analysis and
presentation.
f) Motivating skills of working in team, personal communication, colleagues
and staff respect, and continuous self learning and improvement.
g) Providing the candidates with the basics of quality assurance in
parasitology laboratory
h) Providing knowledge and understanding of the ethics of medical
parasitology profession.
i) Providing knowledge and understanding of the research methodology and
ethics.
2. Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the program the candidate will be able to:
a1) Show knowledge and understanding of the basics of microbiology and
immunology.
a2) Show knowledge and understanding of the basics of biochemistry
especially those of energy pathways, cell cycle, proteins and nucleic
acid structures, functions and manipulations.
a3) Show knowledge and understanding of the basic concepts oe research
methodology and epidemiology.
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a4) List the geographical distribution, final habitat, definitive, intermediate,
and reservoir (host)s of parasites.
a5) Recognize the parasites according to their morphology and microscopic
features.
a6) Understand the biology of parasites
a7) Understand the pathogenesis and clinical manifestations of parasitic
infections.
a8) Describe the methods used for the diagnosis of parasitic infections.
a9) Prescribe drugs for treating different parasites, including dosage and side
effects.
a10) Show awareness of epidemiological factors responsible for the
prevalence of parasitic infections.
a11) Understand the basics of quality assurance parasitology laboratories.
a12) Understand the ethics of the medical parasitology profession.
a13) Understand the the basis of research methodology and ethics.
b. Intellectual capabilities:
By the end of the program the candidate will be able to:
b1 Classify microorganisms according to their morphologic features,
chemical and genomic structures.
b2) Correlate the type of the immune response to the type of the
microorganism.
b3) Formulate protocols for purification of proteins and DNA from
miccorganisms.
b4) Differentiate between and compare the diagnostic and infective stages of
parasites.
b5) Predict and correlate the clinical manifestations with pathogenesis and
pathology.
b6) Analyze a case history of a suspected parasitic infection to reach a
provisional diagnose, give differential diagnosis, and recommend further
investigations to reach the final diagnosis.
b7) Combine different drugs for treating parasitic infections according the
infectious status, presence of complications and drug resistance.
b8) Design plans for prevention and control of parasitic infections and control
of medically important arthropods and snails.
b9) Reading and analyze publications in field of medical parasitology.
c. Professional and practical skills:
By the end of the program the candidate will be able to:
c1 Apply safe laboratory protocols
c2) Prepare sterile media, buffers and reagents.
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c3) Isolate, maintain and culture microorganisms including parasites in the
laboratory.
c4) Prepare standardized antigens of micoorgansms including parasites.
c5) Identify microogansis based on their biochemical and molecular structurs.
c6) Examine urine, stool, blood and other body fluids for parasites using
direct and concentration techniques efficiently and correctly and within
appropriate time.
c7) Apply the proper immunologic assays for the diagnosis of parasitic
infection.
c8) Report the result without delay.
c9) Recommend further investigation.
c10) Collect and analyze data using appropriate statistical and diagrammatic
methods.
c11) Design suitable questionnaires to investigate the epidemiological factors
influencing the prevalence of parasitic diseases, and apply proper
preventive and control measures.
d. General and transferable skills:
By the end of the program the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Show willing and motivations for self learning and improvement of the
department and faculty.
d4) Participate in community services via medical and social campaigns.
d5) Search and retrieve required scientific data via the world wide web and
other electronic resources.
3. Academic standards: (Benchmarks)
Benchmarks (MSc of Medical Parasitology-London School of Hygiene and
Tropical Medicine-London University)
4. Curriculum structure and contents:
4a- Program duration: 4 Semesters (2 years)
4b- Program structure
Curricula
Course Code Credit
hours
Faculty
Requirements
Basics of Research Tools
First Part
Microbiology and Immunology PAR9001 2
Biochemistry PAR9002 2.5
Public Health PAR9003 1.5
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Second Part
Medical Parasitology
Helminthology PAR9004 8
Protozoology and Entomology PAR9005 9
Elective Courses
(Only one course of)
Molecular biology E9002
1 Immunology E9031
Vector biology E9032
Biostatistics E9009
Log Book 6
Total 36
5. Program courses:
Code
No.
Course Title Level/year of
program
No. of hours/week
Lect. Lab.
PAR9001 Microbiology and
Immunology
Semester 1
2
(10 weeks)
2
(10 weeks)
PAR9002 Biochemistry 2
(15 weeks)
2
(8 weeks)
PAR9003 Public health 1
(15 weeks)
1
(15 weeks)
PAR9004
Helminthology:
Trematoda and
Cestoda
Semester 2
3
(15 weeks)
4
(15 weeks)
One of
E9002
E9031
E9032
E9009
Molecular biology
Immunology
Vector biology
Biostatistics
Semester 2
1
(10 weeks)
1
(10 weeks)
PAR9004
Helminthology:
Nematoda
Semester 3 3
(15 weeks)
2
(15 weeks)
PAR9005 Protozoology
- Sarcomastigo
phora
- Ciliophora
Semester 3 2
(15 weeks)
PAR9005
Protozoology
- Apicomplexa
- Microspora
Medical
Entomology
Semester 4 2
(15 weeks)
2
(15 weeks)
2
(15 weeks)
2
(15 weeks)
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6. Program admission requirements:
-:اندبهىو( : يشتزط نقيد انطانب نهحصىل عه درجة 6) انادة
ػه دسخح انثكانىسيىط في انطة واندشازح ي إزذي خايؼاخ خهىسيح يصش - 1 أ يكى زاصال
.انؼشتيح أو ػه دسخح يؼادنح
أ يكى لذ أيض عح انرذسية )االيرياص(. -2
افمح خهح انؼم.يى -3
( 1ذغذيذ انشعىو ويصاسيف انرذسية واعرهالن األخهضج واعريفاء انغرذاخ انطهىتح في انهسك ) -4
انرفشؽ نهذساعح نذج فصهي دساعيي لثم دخىل ايرسا اندضء انثاي. -5
-األوساق انرانيح : انذتهىوح يمذو طانة اإلنرساق نذسخ ( :1يهحق )
. طهة إنرساق. 1
شهادج انثكانىسيىط. .2
. شهادج اإليرياص.3
. شهادج انيالد أو يغرخشج سعي.4
. انىلف ي انرديذ.5
. يىافمح خهح انؼم ػه انرغديم وانرفشؽ انطهىب. 6
صىس فىذىغشافيح خذيذج. 6. ػذد 7
هادج صسيح.. تانغثح نهىافذي يمذو انطانة يىافمح انغفاسج ويسذد خهح ذسم انفماخ كا يمذو ش8
7. Regulation for progression and program completion
يتتشج وازتتذج فتتي انغتتح ذثتتذأ يتت أول يىنيتتى زرتت أختتش أغغتتطظ ػهتت أ ذثتتذأ نهتتذتهىويتترى انرغتتديم (: 8يااادة )
انذساعح فتي شتهش أكرتىتش يت كتم ػتاو ويدتىص لثتىل ذغتديم انتىاب وانؼيتذي وانىافتذي فتي انفرتشج يت أول
ثشزر أختتش ديغتتثش ػهتت أال يغتتر نهتتى تتتذخىل إيرستتا اندتتضء األول إال تؼتتذ إمضتتاء فرتتشج انذساعتتح تتىف
.انطهىتح
ذىصع انذساعح ف كم ػاو خايؼ ػه فصهي دساعيي يذج كتم يهتا خغتح ػاتش اعتثىػا . يثتذا (: 9يادة )
ساع صيف يكثف نذج عترح اعتاتيغ . االول ف أول أكرىتش ويثذا انثا ف يصف فثشايش. يغ ذظيى فصم د
و يترى انرغتديم نهفصتم انذساعت لثتم اعتثىػي يت تذايرتق ػهت االلتم تؼتذ إعتريفاء اناتشوط زغتة انمتتشساخ
عتاػاخ يؼرتذج. ويدتىص نهطانتة ذؼتذيم 6انغدهح. واليثغ أ يضيذ انؼةء انذساع ف انفصم انىازذ ػت
م انذساع )تانسزف او االضافح(. كا يدىص نق االغساب خالل عترق انمشساخ خالل اعثىػي ي تذايح انفص
اعاتيغ ي ازذ انمشاسخ دو ازرغاتق ساعثا فيق.
: يذج انذساعح نهسصىل ػه دسخح انذتهىو ه أستؼح وػاشو شهشا )أستؼح فصىل دساعيح( ( 11انادة )
طثما نهغاػاخ انؼرذج انىضسح تانثاب انشاتغ ػه خضئي يدراص فيها انطانة تشايدا ذذسيثيا يركايال
وال يغر نق تذخىل اإليرسا لثم إعريفاء ثالثح األاطح ويغرىف خالنها انطهىب يح ف كرية يراتؼح
أستاع انطهىب يح في كم خضء ي انثشايح.
ؼذها انطانة إيرساا وال يدراص ت وازذ يذج انذساعح في انذتهىو اندضء األول فصم دساعي ( :12انادة )
نهرذسيةيارشط انداذ فيق تانكايم نإلرمال نهذساعح في اندضء انثاي. واندضء انثاي يرطهة ذفشؽ انطانة
.تأزذ انغرافياخ أو انشاكض انؼرذج ي انكهيح نذج فصهي دساعيي
.كهيح لثم دخىل إيرسا اندضء انثايتإعريفاء يرطهثاخ اندايؼح ويرطهثاخ ان انذتهىويمىو داسط ( : 14يادة )
دسخح ػه األلم( 450يرطهثاخ اندايؼح هي انسصىل ػه شهادج انرىيفم في انهغح اإلدهيضيح تدىع )و
ياهح انثسث انؼهويرطهثاخ انكهيح هي زضىس دوساخ يؼرذج ي ندح انذساعاخ انؼهيا تانكهيح في يدال
ساخ خاصح ذسذدها انهدح. واإلزصاء انطث أو تإخرياص إخرثا
يدىص نهساصهي ػه دسخح انذتهىو إعركال دسخح اناخغريش ترغديم سعانح اناخغريش خالل (: 15يادة )
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أستغ عىاخ ي انسصىل ػه دسخح انذتهىو ويسصم ػه انذسخح تؼذ إعريفاء يرطهثاخ اندايؼح وانكهيح
ويالاح انشعانح تداذ.
ؼرذج نذساعح انذتهىو ثالثى عاػح يؼرذج ػه األلم يخصص يها عد عاػاخ انغاػاخ ان(: 16يادة )
وذام عد عاػاخ ػه األلم نهدضء األول وثاي ػاشج عاػح ػه األلم نهدضء يراتؼح األاطح نكرية
انثاي.
أستغ عىاخ. انذتهىويذج انميذ نذسخح (: 23يادة )
دسخح نهدضء األول. 300دسخح يها 1200نهاخغريش يدىع دسخاخ االيرسا انهائ (: 24يادة )
دسخح نهاخغريش. 300ه انرشاك تا يىاصي صويضاف انيها انؼذل انف
يؼمذ إيرسا انذوس األول في أكرىتش وىفثش ي كم ػاو ويؼمذ إيرسا انذوس انثاي ف أتشيم (: 25يادة )
ويايى ي كم ػاو.
ي انذسخح انكهيح نكم ندا 60 %م يادج ي انذتهىو تؼذ انسصىل ػهيكى انداذ ف ك(: 26يادة )
.% 50ػه اال ذمم دسخح انرسشيشي ػ انادج يدرؼح
(: فتت زانتتح إعتترفار يتتذج انميتتذ يكتت نطانتتة انذساعتتاخ انؼهيتتا إػتتادج انرغتتديم يتتشج أختتشي وال يؼرتتذ 29)يااادة
تانداذ ف اندضء األول أو انشعانح ويدة إػادذها.
8. Assessment Schedule and Weighing of Assessments (Diploma)
Item Mark P
oin
ts
GP
A
sco
re
ةطان
اننح
زا
Stu
den
t
sta
te
During
semester
End of
semester Total
First semester (If present) 100 300 400
Second semester 100 50
(elective)
150
Third semester 100 100
Fourth
semester
Final exam
Written
850 850
Oral
Practical
/Clinical
Total 300 1200 1500
ػه انىخق انران:يهسىظح: ذؼادل دسخاخ انطانة طثما نهماط
ماط 4 : % فأكثش 90 -1 A
ماط 3.63 : % 90% زر ألم ي 85ي -2 A-
ماط 3.33 : %85% زر ألم ي 80ي - 3 B+
14
ماط 3.00 : %80% زر ألم ي 35ي - 4 B
ماط 2.63 : %35% زر ألم ي 30ي - 5 B-
ماط 2.33 : %30% زر ألم ي 65ي - 6 C+
ماط 2.00 : %65% زر ألم ي 62ي -3 C
ماط 1.63 : %62% زر ألم ي 60ي - 8 C-
F صفش : %60ألم ي - 9
دسخح نهدضء ويضاف إنيها 300دسخح يها 1200يدىع دسخاخ االيرسا انهائ نهذتهىو انؼان
.دسخح 300ه انرشاك تا يىاصي صانؼذل انف
( ػه أعاط يدىع زاصم ضشب ماط كم يمشس يضشوتا فت GPAويرى زغاب انؼذل انفصه )
ػذد عاػاذق انؼرذج يمغىيا ػه انغاػاخ انؼرذج نهمشساخ انر دسعها انطانتة فت انفصتم انذساعت. كتا
( ػه أعاط يدىع زاصم ضتشب انمتاط انرت زصتم ػهيهتا CGPAانؼذل انرشاك نهطانة ) يرى زغاب
وتا ف ػذد عاػاذق انؼرذج يمغىيا ػه يدىع انغاػاخ انؼرذج انكهيح.انطانة ف كم يمشس يضش
يرى اإلػادج ف انتادج أو واناخغريشف انذتهىو أمشساخ انف زانح انشعىب ف يادج أو يدىػح ي
يسغتة ويرى زغاب انرمذيش انفؼه انزي يسصم ػهيق ف أول إػتادج فمتظ أيتا إرا ذكتشس سعتىتح فاندىػح فمظ.
ماط اي 1.63% فمظ )اي60نق ػذ انداذ ذمذيش -
C).
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1. Course specification for Microbiology and Immunology
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: major
Department offering the program: Parasitology Department
Department offering the course: Medical Microbiology and Immunology
Academic year / Level: First year/ First semester
Date of specification approval ……………………………………..
A- Basic Information
Title: Microbiology and Immunology Code: PAR9001
Credit Hours: 2
Lecture: 2hours/w (10w) Practical: 2hours/w (10w) SDL
Total: 20 theoretical and 20 practical hours.
Coordinator
Head of the department
B - Professional Information
1- Course Aims:
To introduce the candidate to the basics of microbiology and immunology
including:
a) The nature of viruses, bacteria, parasites and fungi and basic criteria used
in the classification/taxonomy of these micro-organisms.
b) Microbial genetics.
c) Microbial physiology including growth requirements and metabolism.
d) Methods of sterilization and disinfection.
e) Virulence factors of microorganisms.
f) Basics of the immunity to microorganisms including types of the
immunity; structure, function and organization of the immune system.
g) Types of the immune response and phases of the adaptive immune
response.
h) Basics of cellular and humoral immune response.
2- Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the course the candidate will be able to:
a1) Identify eukaryotic and prokaryotic cell structure.
a2) Describe the basic structure and function of components of the bacterial
cell.
a3) Understand classification systems and typing of microorganisms.
a4) Understand the basics of bacterial growth, physiology, energy production.
16
a5) Understand the basics of microbial genetics including genomic
organization, DNA conjugation, transformation, and transduction.
a6) Describe mechanisms and applications of different methods used for
sterilization and disinfection.
a7) Understand the virulence factors responsible for microbial pathogenecity.
a8) Understand the nature and type of immunity.
a9) Understand the organization (anatomy) and function of the immune
system.
a10) Understand the phases and characteristics of the adaptive immune
response.
a11) Understand the basics of nosocomial and laboratory acquired infections.
b) Intellectual skills
By the end of the course the candidate will be able to:
b1) Differentiate between prokaryotes and eukaryotes.
b2) Compare the different types of microscopes.
b3) Interpret the tests for monitoring the efficiency of sterilization process.
b4) Differentiate between the types of immunity and immune response.
b5) Formulate a systematic approach for laboratory diagnosis of common
infectious clinical conditions using the most appropriate and cost-
effective tool leading to the identification of the causative organism.
c) Professional and practical skills:
By the end of the course, candidate will be able to:
c1) Apply safe laboratory protocols.
c2) Prepare slides for microbiological examination.
c3) Stain microorganisms using simple and differential techniques.
c4) identify the microorganisms according to their shape, arrangement,
staining and biochemical and culture characteristics.
c5). Apply the proper method for sterilization of different media.
c6) Use properly aseptic techniques for the transfer and handling of
microorganisms and instruments.
c7) Apply the proper method of disinfection.
c8) Isolate microorganisms form different specimens.
c9) Estimate the number of microbes in a sample using serial dilution
techniques.
c10) Perform some biochemical tests for the identification of bacteria.
c11) Perform in vitro susceptibility and resistance of bacteria of antibiotics
using disc diffusion and dilution methods.
c12) Apply the proper methods of prevention of laboratory acquired
infections.
d) General and transferable skills:
By the end of the course the candidate will be able to:
17
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Show willing and motivations for self learning and continuous improvement.
d4) Represent data efficiently.
d5) Search and retrieve required scientific data via the world wide web and
other electronic resources.
3- Course contents:
Topics No of hours
Lecture Practical
2hours/w 2 hours/week
Bacterial cell structure 2
Classification and typing of
microorganisms.
1
Bacterial growth, physiology 2
Bacterial genetics 2
Control of microbial growth 4
Antimicrobials 2
Host parasite relationship 2
Nosocomial acquired infections 2
Tissues and cells of the immune
system
2
Types of immune response
(innate and adaptive)- cellular
immune response
2
Antigens and immunogenicity 1
Humoral immune response
(Immunoglobulins and
complement
2
Cell mediated immunity and
cytokines
2
Lab Safety 1
Types of microscopes 1
Collection of pathological
specimens
2
Isolation of microorganisms
from different specimens
2
Estimation of number of
microbes in samples
2
Biochemical tests for 2
18
identification of isolates
Antimicrobial susceptibility
tests
2
Basic immunological techniques
as agglutination, precipitation
and complement fixation.
2
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills.
4.2 Practical exams to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills.
Marks distribution:
Written: 60 Marks Practical: 30 Marks Oral: 10 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books)
a) Jawetz, Melnick, and Adelberg’s medical microbiology, 24th
Edition,
2007, Brooks J.F., Carroll K.C., Butel J.S., and Morse S.A.
b) Medical Microbiology, 17th
edition, 2007, Greewood D., Slack R.,
Peutherer J., and Barer M.
c) Mackie and MaCatney Pratical Medical Microbiology,14th
Edition, 1996, Collee J.G., Fraser A.G., Marmion B.P., and Simmons
A.
d) District Laboratory Practice in Tropical Countries, part 2, 2000,
Cheesbrough M., Cambridge Press.
e) Microbiology: An Introduction (10th Edition) by Gerard J. Tortora,
Berdell R. Funke, and Christine L. Case.
f) Bailey & Scott's Diagnostic Microbiology.
5.3- Recommended Books
a) Microbiology: An Introduction (10th Edition) by Gerard J. Tortora,
Berdell R. Funke, and Christine L. Case.
b) District Laboratory Practice in Tropical Countries, part 2, 2000,
Cheesbrough M., Cambridge Press.
5.4- Periodicals, Web Sites, etc
a) Center for disease control and prevention:www.cdc.gov
b) Medscape:www.medscape.com/infectious diseases
c) Pubmed:www.ncbi.nlm.nih.gov/pubmed
d) World health organization: www.who.int/en
19
2. Course specification for Biochemistry
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: major
Department offering the program: Parasitology Department
Department offering the course: Biochemistry
Academic year / Level: First year/ First semester
Date of specification approval ……………………………………..
A- Basic Information
Title: Biochemistry Code: PAR9002
Credit Hours: 2.5
Lecture: 2hours/w (15w) Practical: 2hours/w (15w) SDL
Total: 30 theoretical and 15 practical hours
Coordinator
Head of the department
B- Professional Information
1. Course Aims:
To introduce the candidate to the basics of protein and nucleic acids structure,
function and manipulation including
a) Basic structure and functions of proteins.
b) Basic structure, functions and organization of nucleic acids.
c) Cell cycle.
d) DNA replication, transcription and translation.
e) Basic structure and function of the biological membranes.
f) Proteins and nucleic acid manipulations.
2. Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the course the candidate will be able to:
a1) Describe the basic structure and functions of proteins.
a2) Describe the basic structure, function and organization of nucleic acids.
a3) Understand major biochemical pathways of energy production.
a4) Understand the structure, mechanism of action of enzymes and their
application in diagnosis of infections and diseases.
a5) Understand the cell cycle.
a6) Understand the basics of purification and separation of proteins.
a7) Understand the basics of chromatography and electrophoresis.
a8) Understand the basic of DNA manipulations as purification, synthesis and
sequencing.
20
a9) Understand the principle of spectrophotometry.
a10) Understand the basics of buffering and pH.
b) Intellectual skills
By the end of the course the candidate will be able to:
b1) Compare the structures of DNA and RNA.
b2) Predict the amino sequence of a given codons.
b3) Estimate the amount of ATP produced during aerobic and anaerobic
respiration.
b4) Formulate protocols for the purification of proteins and DNA from some
parasitic stages.
Professional and practical skills:
By the end of the course, candidate will be able to:
c1) Apply safe laboratory protocols.
c2) Prepare buffers of defined pH and molarities.
c3) Separate proteins by SDS polyacrylamide gel electrophoresis.
c4) Measure protein concentration by Lowery and Bradford techniques.
c5) Measure concentrations of some analytes by spectrophotometer.
c5) Extract DNA.
c6) Measure the concentration of DNA in samples.
c) General and transferable skills:
By the end of the course the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Show willing and motivations for self learning and continuous
improvement.
d4) Represent data efficiently.
d5) Search and retrieve required scientific data via the World Wide Web
and other electronic resources.
3- Course contents:
Topics No of hours
Lecture Practical
Bio-molecules (Carbohydrates,
lipids and proteins)
2
Structure and Functions of Proteins 4
- Structure and Functions of
Nucleic acids
- DNA replication and transcription
- Genes to proteins
6
Nucleic acid manipulation:
amplification, sequencing,
4
21
restriction analysis, blotting, etc.
Cell cycle 2
Genomic organization, genetic code 4
Enzymes: structure, function,
isoenzymes, etc.
4
Bioenergetics 2
Biological membranes 2
Chromatography 2
Electrophoresis 2
Protein purification and separation 4
Principles of spectrophotometry 2
Molarity, molality, hydrogen ion
concentration, pH, buffering,
preparation of buffers of certain pH
and molarity
4
Measuring of protein and DNA
concentration
2
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills
4.2 Practical exams to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills
Marks distribution:
Written: 75 Marks Practical: 37.5 Marks Oral: 12.5 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books)
a) Biochemistry (3rd Edition) (Biochemistry (Mathews/ Addison-
Wesley).
b) Principles of Biochemistry (4th Edition) by Robert Horton, Laurence
A Moran, Gray Scrimgeour, and Marc Perry.
c) Harper's Illustrated Biochemistry, 28th Edition (LANGE Basic
Science) by Robert Murray, Victor Rodwell, David Bender, and
Kathleen M. Botham.
d) Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson,
Julian Lewis, and Martin Raff.
e) Molecular Cell Biology by Harvey Lodish, Arnold Berk, Chris A.
Kaiser, and Monty Krieger.
22
5.3- Recommended Books
a) Harper's Illustrated Biochemistry, 28th Edition (Lange Basic Science)
by Robert Murray, Victor Rodwell, David Bender, and Kathleen M.
Botham
b) Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson,
Julian Lewis, and Martin Raff 5.4- Periodicals, Web Sites, etc
5.4- Periodicals, Web Sites, etc
a) Pubmed: http://www.ncbi.nlm.nih.gov/
b) DNA from the beginning: http://www.dnaftb.org/dnaftb/
23
3. Course specification for Public Health
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: major
Department offering the program: Parasitology Department
Department offering the course: Community, Environmental and Occupational
Medicine
Academic year / Level: First year/ First semester
Date of specification approval ……………………………………..
A- Basic Information
Title: Public Health Code: PAR9003
Credit Hours: 1.5
Lecture: 1 hour/w (10w) Practical: 1 hour/w (10w) SDL
Total: 15 theoretical and 15 practical hours
Coordinator
Head of the department
B - Professional Information
1. Course Aims:
To provide an introduction to the basic concepts research methodology and
epidemiology.
Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the course the candidate will be able to:
a1) Understand the basics of disease surveillance.
a2) Understand and apply measures of disease incidence (risk, rate and odds)
and prevalence, and measures of effect (e.g. relative and absolute risk).
a3) Demonstrate understanding of the basic principles underlying different
study designs, including cross-sectional, cohort, case-control and
intervention studies.
a4) Understand the concepts of estimation of sensitivity, specificity and
predictive values.
a5) Understand the basics of clinical trials.
a6) Know the epidemiological factor responsible for the prevalence of
parasitic diseases in Egypt.
a7) Understand the basics of questionnaire design.
b) Intellectual skills
By the end of the course the candidate will be able to:
b1) Assess strengths and limitations of different study designs.
24
b2) Identify problems caused by random errors, bias and confounding in
interpreting epidemiological data.
b3) Estimate sensitivity, specificity and predictive values.
c) Professional and practical skills:
By the end of the course, students will be able to:
c1) Measure disease incidence and prevalence of parasitic diseases.
c2) Design the proper study for investigation of parasitological problems.
c3) Estimate sensitivity, specificity and predictive values for
parasitological laboratory tests.
c4) Design suitable questionnaires to investigate the epidemiological
factors influencing the prevalence of parasitic diseases.
c4) Apply the proper measures to control and prevent parasitic infections.
d) General and transferable skills:
By the end of the program the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Show willing and motivations for self learning and continuous
improvement.
d4) Represent data efficiently.
d5) Search and retrieve required scientific data via the World Wide Web
and other electronic resources.
3- Course contents:
Topics No of hours
Lecture Practical
Aim of Research 1
Research Design
- Sampling
- Cohort studies
- Cross sectional studies
- Case control studies
- Intervention studies
2
1
1
1
1
4
Research tools
Sensitivity and specificity
Questionnaires
2
2
2
4
Measuring of disease frequency 2 2
Surveillance for disease 2 3
25
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills.
4.2 Practical exams to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills.
Marks distribution:
Written: 45 Marks Practical: 22.5 Marks Oral: 7.5 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books)
a) Modern Epidemiology by Kenneth J Rothman, Sander Greenland,
and Timothy L Lash.
b) Epidemiology for Public Health Practice by Robert Friis and Thomas
Sellers.
c) Epidemiology: An Introduction by Kenneth J. Rothman
d) Essentials of Epidemiology in Public Health, Second Edition by Ann
Aschengrau; George R. Seage.
e) Introduction to Epidemiology by Ray M. Merril and Thomas C.
Timmreck.
5.3- Recommended Books (Text Books)
Handbook of Epidemiology. Springer 2005
5.4- Periodicals, Web Sites, etc
a) http//.www. Epidemiolog.net
26
4. Course specification for Parasitology
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: Major
Department offering the program: Parasitology Department
Department offering the course: Parasitology Department
Academic year / Level: First and second years/ second through fourth semesters.
Date of specification approval ……………………………………..
A- Basic Information
Title: Helminthology Code: PAR9004
Credit Hours: 8
Lecture: 3 hour/w (30w) Practical: 4 hour/w (15w) SDL
Total: 90 theoretical and 60 practical hours
Title: Protozoology and Entomology Code: PAR9005
Credit Hours: 9
Lecture: 3 hour/w (30w) Practical: 3 hour/w (30w) SDL
Total: 90 theoretical and 90 practical hours
Coordinator
Head of the department
B - Professional Information
1. Course Aims:
a) Providing a broad-based knowledge and understanding of Medical
Parasitology including Helminthology, Malacology, Protozoology and
Medical Entomology.
b) Providing practical skills and experience in the laboratory diagnosis of
parasitic infections.
c) Providing knowledge and understanding in research methodology and
ethics, study planning, and data reporting, analysis and presentation.
d) Motivating skills of working in team, personal communication, colleagues
and staff respect, and continuous self learning and improvement.
2. Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the program the candidate will be able to:
a1) Locate the geographical distribution of parasites in the world and in
Egypt.
a2) Name the final habitat, definitive, intermediate, and reservoir hosts of the
parasite.
a3) Recognize the parasites according to their morphology and microscopic
features.
27
a4) Recognize medically important arthropods according to their morphologic
features.
a5) Identify the snails acting as intermediate hosts of trematodes studied
according to their external features and morphology of the shells.
a6) Understand the physiology (reproduction, nutrition, respiration, secretion,
excretion, locomotion) of parasites and bionomics of medically
important arthropods.
a7) Understand the ecology of snails including physical factors (water level
and movement, nature of water body, vegetation in water, depth of water
and altitude), sunlight and shade, temperature, and chemical factors
(Oxygen, calcium, pollution).
a8) Describe and draw the life cycle of parasites.
a9) Mention the modes of transmission and infective stage(s).
a10) Draw labeled diagrams of diagnostic and infective stage(s).
a11) Understand the pathogenesis, pathology of parasitic infections.
a12) Tell the clinical manifestations of parasitic infections.
a13) Tell the medical importance of arthropods including the modes and ways
of transmission.
a14) Describe the methods used for the diagnosis of parasitic infections.
a15) Prescribe drugs for treating different parasites, including dosage and side
effects.
a16) Show awareness of epidemiological factors responsible for the
prevalence of parasitic infections.
a17) Understand methods of prevention and control parasitic infections.
a18) Understand methods of control of medically important arthropods.
a19) Understand methods of control of medically important snails.
b) Intellectual capabilities:
By the end of the program the candidate will be able to:
b1) Classify the parasites according to their morphologic and microscopic
feature.
b2) Classify medically important arthropod and snails according to their
morphologic features.
b3) Construct attractive explanatory drawing for life cycle, infective stage and
modes of infection.
b4) Differentiate between and compare the diagnostic and infective stages of
parasites.
b5) Predict and correlate the clinical manifestations with pathogenesis and
pathology.
b6) Explore the differential diagnosis on the basis of suspected clinical
manifestations and recommend the relevant further investigations.
28
b7) Evaluate the infectious status; acute, chronic, or latent, from the given
manifestations and the available diagnostic tests.
b8) Combine different drugs for treatment according the infectious status,
presence of complications and drug resistance.
b9) Advise people travelling endemic areas, concerning prophylactic health
measures and use of prophylactic drugs.
b10) Design plans for prevention and control of parasitic infections and
control of medically important arthropods and snails.
c) Professional and practical skills:
By the end of the program the candidate will be able to:
c1) Apply safety measures in the parasitology laboratory.
c2) Maintain the equipments in the parasitology laboratory.
c3) Respect patients and their relatives and communicate with them
efficiently for full history taking.
c4) Examine urine, stool, blood and other body fluids for parasites using
direct and concentration techniques efficiently and correctly and within
appropriate time.
c5) Differentiate between parasitic stages and artifacts that might be present
in samples.
c6) Honestly reporting the result without delay.
c7) Report results for seniors if required.
c8) Recommend further investigation.
c9) Contact treating physician for inquiring information that might be helpful
for the laboratory diagnosis as well as to report urgent cases.
c10) Apply the appropriate stain needed for each specimen.
c11) Preserve and culture faecal and other parasitological specimens.
c12) Preserve worms, protozoa and insects and prepare microscopic slides.
c13) Identify, classify and draw helminthes, protozoa, and snails and
arthropod of medical importance.
c14) Apply and interpret the appropriate immunological test for diagnosis of
parasitic infections.
c15) Collect and analyze data using appropriate statistical and diagrammatic
methods.
d) General and transferable skills:
By the end of the program the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Help colleagues in pursuing their research activities.
d4) Show willing and motivations for self learning and continuous
improvement.
29
d5) Show willing and motivation for improvement of the department and
faculty.
d6) Show competence, efficiency and honesty in all assigned scientific and
social activity.
d7) Represent data efficiently.
d8) Work in challenging and competitive environment.
d9) Search and retrieve required scientific data via the World Wide Web and
other electronic resources.
d10) Show interest in local health problems.
d11) Participate in community services via medical and social campaigns.
3. Course content:
A) Theory
Course title Hours
1. INTRODUCTION AND CLASSIFICATION
OF PARASITES
- Historical Perspectives
- Host-Parasite relationship
- Clinical manifestations of parasitic diseases
- Prevalence and transmission of parasitic infections
- Taxonomy and classification
6
2 HELMINTHS.
PHYLUM PLATYHELMINTHES
CLASS: TREMATODA
Introduction
Family: Fasciolidae
Family: Opisthorchiidae
Family: Heterophyidae
Family: Echinostomatidae
Family: Dicroceliidae
Family: Gastrodiscidae
Family: Schistosomatidae
Family: Troglotrematidae
MEDICAL MALACOLOGY
CLASS: CESTOIDEA
Introduction
Family: Diphyllobothriidae
Family: Taeniidae
Family: Dilepididae
Family: Hymenolipedidae
2
4
2
1
1
1
1
6
2
4
2
3
6
2
2
30
PHYLUM NEMATHELMINTHES
Introduction
CLASS: ADENOPHOREA
Family: Trichuridae
Family: Capillaridae
Family: Trichinellidae
Family: Dioctophymatidae
CLASS: RHABDITEA Family: Strongyloididae
Family: Ancylostomidae
Family: Trichstrongylidae
Family: Angiostrongylidae
Family: Ascarididae
Family: Oxyuridae
Family: Dracunculoidae
Family: Gnathostomatoidae
Family: Anisakidae
Family: Physalopteridae
Family: Gongylonematidae
Family: Filariidae
Family: Onchoceridae
Family: Thelaziidae
3
2
2
4
2
3
3
1
1
3
2
2
2
1
1
1
3
2
1
3. Immune Response to Helminthes 6
4. PROTOZOA
Introduction
PHYLUM SARCOMASTIGOPHORA
CLASS: RHIZOPODA
Family: Endamoebidae
Family: Acanthamoebidae
Family: Vahlkampfiidae
CLASS: ZOOMASTIGOPHORFA Family: Trypanosomatidae
Genus: Leishmania
Genus: Trypanosoma
Family: Bodonidae: Genus: Retortamonas
Family: Tetramitidae Genus: Enteromonas
Family: Hexamitidae Genus: Giardia
Family: Chilomastigidae Genus: Chilomastix
Family: Monocercomonadidae Genus: Dientamoeba
3
6
15
31
Family: Trichomonadidae Genus: Trichomonas
PHYLUM CILIOPHORA Family: Balantidiidae
PHYLUM APICOMPLEXA (SPOROZOA)
SUBCLASS: COCCIDIA
SUBORDER: EIMERIINA Family: Cryptosporidiidae
Family: Eimeriidae (Eimeria and Isospora)
Family: Sarcocystidae (Toxoplasma and Sarcocystis)
SUBORDER: HAEMOSPORINA Family: Plasmodiidae
SUBCLASS PIROPLASMEA Family: Babesiidae
PHYLUM MICROSPORA Family: Nosematidae
1
6
6
2
3
5. Immune Response to Protozoa 6
6. Nosocomial parasitic infections: 3
7. Parasitic infections of compromised host 3
8. Symptoms and sign sof parasitic infections
6
9. MEDICAL ENTOMOLOGY
Introduction
CLASS INSECTA
SUBCLASS: ENDOPTERYGOTE INSECTS (Holometabola) I. ORDER: DIPTERA [Mosquitoes and Flies]
A) SUBORDER: NEMATOCERA
Family: Psychodidae (Blood sucking sand flies and non-biting moth-
flies)
Family: Anisopodidae (Window-gnats) (Facultative accidental
intestinal myiasis)
Family: Culicidae (Mosquitoes)
Genus: Anopheles Genus: Culex Genus: Aedes
Family: Simuliidae (Black flies, Buffalo gnat)
Family: Ceratopogonidae (Biting midges)
2
4
32
Family: Tipulidae (Facultative accidental intestinal
myiasis)
B) SUBORDER: BRACHYCERA
1. Infraorder: Tabanomorpha
Family: Tabanidae
Genus: Tabanus (Horse-flies - Myiasis)
Genus: Chrysops (Deer-flies)
2. Infraorder: Muscomorpha (Cyclorrapha)
a) Section: Aschiza
Family: Syrphidae (Hover-flies, Drone-flies)
Genus: Erystalis
b) Section: Schizophora:
Family: Glossinidae
Family: Muscidae (Myiasis)
Family: Fanniidae (Myiasis)
Family: Oestridae (Head maggots-Myiasis)
Family: Calliphoridae (Blow flies-Myiasis)
Family: Sarcophagidae (Flesh flies- Myiasis)
Family: Gastrophilidae
Family: Hypodermatidae
Family: Cuterebrinae (Skin bot flies-Myiasis)
II. ORDER: SIPHONEPTERA [Fleas]
Family: Pullicidae
Family: Tungidae
SUBCLASS EXOPTERYGOTA (Hemimetabola)
I. ORDER : PHTHIRAPTERA
SUBORDER: ANOPLURA (Lice: biting lice and sucking lice)
Family: Pediculidae
Family: Phthiridae
II. ORDER: HEMIPTERA
SUBORDER: HETRROPTERA
Family: Cimicidae
Family: Cacodmidae
Family: Reduviidae
CLASS ARACHNIDA
SUBCLASS: ACARI
I. ORDER: PARASITIFORMES
A) SUBORDER: IXODIDA (Metastigmata: TICKS)
3
2
3
6
33
Family: Ixodidae (Hard Ticks)
Family: Argasidae (Soft Ticks)
B) SUBORDER: GAMASIDA (Mesostigmata: MITES)
Family: Dermanyssidae
Family: Macronyssidae
Family: Laelapidae
II.ORDER: ACARIFORMES A) SUBORDER: ACARIDIDA (Astigmata)
Family: Sarcoptidae (Sarcoptes scabiei)
Family: Pyroglyphidae (House dust mites)
Family: Acaridae
Family: Glycyphagidae
B) SUBORDER: ACTINEDIDA (Prostigmata)
FFaammiillyy: Demodicidae
Family: Trombiculidae
SUBCLASS ARANAE (SPIDERS)
SUBCLASS SCORPIONES (SCORPIONS)
CLASS CRUSTACEA
I. SUBCLASS COPEPODA
ORDER: EUCOPEPODA
II. MALACOSTRACA ORDER: DECAPODA (Cray fish, Lobster, Crabs)
Basics of vector biology
2
4
34
B) Practical
Course title Hours
Unit 1
Safety measures in parasitology laboratory
Equipping of parasitology laboratory
Maintenance, cleaning of microscopes, balances
Preparation of buffers, stains and reagents
6
Unit 2
Stool Examination
1. Collection, preservation and transport of faecal specimens
2. Macroscopic examination
3. Microscopic examination
- Direct smear method
- Stool concentration techniques
- Reporting of the results
- Quality control
- Egg counting techniques (Kato-katz, Stoll's)
- Stool staining techniques (Trichrome, Iron hematoxylin,
Modified Trichrome, Modified Ziehl-Neelsen)
4. Culture of larval stage of Nematodes
5. Stool artifact
14
Unit 3
Examination of Blood for Parasites
1. Collection of blood specimens
2. Preparation of thin and thick blood films
3. Staining of blood films
4. Reporting of the results
10
Unit 4
Examination of other specimens
Urine, CSF, sputum, LN, skin biopsies, and vaginal washout
6
Unit 5
Preparation of permanent microscopic slides (helminths, protozoa,
arthropods)
4
Unit 6
Serodiagnosis of parasitic infections (IHA, ELISA, IB)
6
35
Unit 7
Examination of permanent microscopic slides and specimens
Helminths
CLASS: TREMATODA
Family: Fasciolidae (Fasciola gigantica, F. hepatica, Fasciolopesis
buski)
Family: Opisthorchiidae (Clonorchis sinensis, Opisthorchis felineus)
Family: Heterophyidae (Heterophyes heterophyes, Metagonimus
yokogawai
Family: Echinostomatidae (Echinostoma ilocanum)
Family: Dicroceliidae (Dicrocoelium dendriticum)
Family: Gastrodiscidae (Gastrodiscoides homonis)
Family: Schistosomatidae (Schistosoma haematobium,
S. mansoni, S. japonicum)
Family: Troglotrematidae (Paragonimus westermani)
CLASS: CESTOIDEA
Family: Diphyllobothriida (Diphyllobothrium latum, Spirometra
mansonoides)
Family: Taeniidae
Taenia saginata, Taenia solium
Echinococcus granulosus, Echinococcus multilocularis
Family: Dilepididae (Dipylidium caninum)
Family: Hymenolipedidae (Hymenolepis nana, Hymenolepis diminuta)
PHYLUM: NEMATHELMINTHES
Family: Trichuridae (Trichocephalus trichuris)
Family: Capillaridae (Capillaria hepatica, Capillaria
philippinensis )
Family: Trichinellidae (Trichinella spiralis)
Family: Strongyloididae (Strongyloides stercoralis)
Family: Ancylostomidae (Ancylostoma duodenale,A. braziliense, A.
caninum, Necator americanus, Ternidens diminutus, Oesophagostomum
apiostomum)
Family: Ascarididae (Ascaris lumbricoides)
Family: Oxyuridae (Enterobius vermicularis)
Family: Filariidae (Wuchereria bancrofti, Dirofilaria immitis)
Family: Onchoceridae (Onchocerca volvulus)
10
6
12
36
PHYLUM: MOULLUSCA (SNAILS)
PROTOZOA
PHYLUM SARCOMASTIGOPHORA
CLASS: RHIZOPODA
Family: Endamoebidae
Entamoeba histolytica
Entamoeba hartmani
Entamoeba dispar
Entamoeba gingivalis
Endolimax nana
Iodamoeba butschlii
CLASS: ZOOMASTIGOPHORFA Family: Trypanosomatidae
Genus: Leishmania
Leishmania donovani complex
Leishmania tropica complex
Leishmania braziliensis compelx
Leishmania mexicana complex
Genus: Trypanosoma
Trypanosoma brucei
Trypanosoma brucei gaimbiens
Trypanosoma brucei rhodesiense
Trypanosoma cruzi
Trypanosoma rangeli
Trypanosoma lewisi
Family: Bodonidae: Genus: Retortamonas
Family: Tetramitidae Genus: Enteromonas
Family: Chilomastigidae Genus: Chilomastix
Family: Hexamitidae Genus: Giardia
Family: Monocercomonadidae Genus: Dientamoeba
Family: Trichomonadidae Genus: Trichomonas
PHYLUM CILIOPHORA Family: Balantidiidae
PHYLUM APICOMPLEXA (SPOROZOA)
SUBCLASS: COCCIDIA
SUBORDER: EIMERIINA
2 6
12 6 2 6
37
Family: Cryptosporidiidae (Cryptosporidium spp)
Family: Eimeriidae (Eimeria spp and Isospora spp)
Family: Sarcocystidae (Toxoplasma gondii and Sarcocystis spp)
SUBORDER: HAEMOSPORINA Family: Plasmodiidae
Plasmodium vivax
Plasmodium ovale
Plasmodium malariae
Plasmodium falciparum
Plasmodium berghie
SUBCLASS PIROPLASMEA Family: Babesiidae
MEDICAL ENTOMOLOGY
CLASS INSECTA
SUBCLASS: ENDOPTERYGOTE INSECTS (Holometabola) I. ORDER: DIPTERA [Mosquitoes and Flies]
A) SUBORDER: NEMATOCERA
Family: Psychodidae (Bloodsucking sandflies and non-biting moth-
flies)
Family: Culicidae
Genus: Anopheles
Genus: Culex
Genus: Aedes
Family: Simuliidae (Black flies, Buffalo gnat)
Family: Ceratopogonidae (Biting midges)
B) SUBORDER: BRACHYCERA
1. Infraorder: Tabanomorpha
Family: Tabanidae
Genus: Tabanus (Horse-flies - Myiasis)
Genus: Chrysops (Deer-flies)
2. Infraorder: Muscomorpha (Cyclorrapha)
a) Section: Aschiza
Erystalis spp
b) Section: Schizophora:
Family: Hypodermatidae (Hypoderma bovis))
Family: Glossinidae (Glossina spp)
Family: Muscidae (Musca domestica, Stomoxys
calcitrans)
8 2
10 4
38
Family: Fanniidae (Fannia spp)
Family: Oestridae (Oestrus ovis)
Family: Calliphoridae (Calliphora, Lucilia, Chrysomia)
Family: Sarcophagidae (Sarcophaga, Wohlfartia spp)
Family: Cuterebrinae (Dermatobia hominis)
II. ORDER: SIPHONEPTERA [Fleas]
Family: Pullicidae
Pulex irritans
Ctenocephalides canis
Ctenocephalides felis
Xenopsylla cheopis
Xenopsylla braziliensis
Xenopsylla astia
Family: Tungidae
Tunga penetrans
Nosopsyllus fasciatus
Leptopsylla segnis
SUBCLASS EXOPTERYGOTA (Hemimetabola)
I. ORDER : PHTHIRAPTERA SUBORDER: ANOPLURA (Lice: biting lice and sucking lice)
Family: Pediculidae : ( Pediculus humanus capitis,
Pediculus h. corporis
Family: Phthiridae ( Phthirus pubis)
II. ORDER: HEMIPTERA (Bugs, cicads, aphids, and scale insects)
SUBORDER: HETRROPTERA
Family: Cimicidae (Cimex lectularius)
Family: Reduviidae (Triatoma megista)
CLASS ARACHNIDA
SUBCLASS: ACARI
I. ORDER: PARASITIFORMES
SUBORDER: IXODIDA (Metastigmata: TICKS)
Family: Ixodidae (Hard Ticks)
Family: Argasidae (Soft Ticks)
II.ORDER: ACARIFORMES A) SUBORDER: ACARIDIDA (Astigmata)
Family: Sarcoptidae (Sarcoptes scabiei)
4 4 6
39
Family: Pyroglyphidae (House dust mites)
B) SUBORDER: ACTINEDIDA (Prostigmata)
FFaammiillyy: Demodicidae
Family: Trombiculidae
SUBCLASS ARANAE (SPIDERS)
SUBCLASS SCORPIONES (SCORPIONS)
CLASS CRUSTACEA
I. SUBCLASS COPEPODA ORDER: EUCOPEPODA (Cyclops)
II. SUBCLASS: MALACOSTRACA ORDER: DECAPODA (Cray fish, Lobster, Crabs)
2 2
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills.
4.2 Practical exams to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills.
Marks distribution:
Helminthology (1 paper)
Written: 240 Marks Practical: 120 Marks Oral: 40 Marks
Protozoology and Entomology (1 paper)
Written: 270 Marks Practical: 135 Marks Oral: 45 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books) a) Clinical Parasitology: by Craig, Faust , Beaver (Lippincott
Williams & Wilkins, US; 9th edition).
b) Manson's Tropical Diseases: by Cook and Zumla (Saunders Ltd.;
21st edition).
c) Foundations of Parasitology: by Schmidt and Roberts (Times Mirror
/ Mosby College Publishing).
d) Foundations of Parasitology: by Roberts and Janovy (McGraw-Hill
Higher Education; 7th
edition).
e) Human Parasitology: by Bogitsh, Carter, Oeltmann (Academic
Press 3rd
edition).
f) Medical Parasitology: A Practical Approach: by Gillespie, Hawkey
(Oxford University Press).
g) Modern Parasitology: by F.E.G. Cox (Blackwell Science, UK)
40
h) Parasitology and Vector Biology: by Marquardt, Demaree (Grieve
Academic Press; 2nd
edition).
i) Diagnostic Medical Parasitology: by Garcia (American Society for
Microbiology; 5th
edition).
j) Markell and Voge's Medical Parasitology: by John , Petri
(Saunders; 9th edition).
k) Atlas of Tropical Medicine and Parasitology: by Peters and Pasvol
(Mosby 6th
edition).
l) Immunology and Molecular Biology of Parasitic Infections: by
Warren (Blackwell Science Ltd; 3rd Ed edition).
m) Immunity to Parasites: How Parasitic Infections are Controlled: by
Wakelin (Cambridge University Press; 2nd
edition).
n) Biology of Parasitism: by David, Tschudi, Pearce (Kluwer
Academic Publishers, 2000).
5.3- Recommended Books
a) Diagnostic Medical Parasitology: by Garcia (American Society
for Microbiology; 5th
edition).
b) Manson's Tropical Diseases: by Cook and Zumla (Saunders
Ltd.; 21st edition).
5.4- Periodicals, Web Sites, etc
a) Egyptian Journal of Parasitology
b) Parasitologists United Journal
c) Egyptian Journal of Basic Sciences
d) Egyptian Journal of Immunology
e) American Journal of Tropical Medicine and Hygiene
f) Transaction of Royal Society of Tropical Medicine and Hygiene
g) Journal of Clinical Microbiology
h) Journal of Infectious Diseases
i) European Journal of Clinical Microbiology
j) Journal of Eukaryotic Microbiology
k) Parasitology Research
l) Parasite Immunology
m) Infection and Immunity
n) Journal of Immunology
o) International Parasitology
p) Journal of Parasitology
q) Clinical Microbial Review
r) Journal of Helminthology
s) Applied and Environmental Microbiology
t) WHO: www.who.int
41
u) Parasitology Division, Center of Disease Control:
www.cdc.dpdx.gov
v) Pubmed: www.ncbi.nlm.nih.gov
w) Clinical Microbial Review: www.cmr.asm.org
x) American Society of Microbiology: www.asm.org
y) TDR, a Special Programme for Research and Training in Tropical
Diseases: www.who.int/tdr/
z) The World Organisation for Animal Health (OIE):
http://www.oie.int/
Course Specification of Elective Courses
1. Course specification for Molecular Biology
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: Minor.
Department offering the program: Parasitology Department
Department offering the course: Biochemistry Department
Academic year / Level: First year/ second semester
Date of specification approval ……………………………………..
A- Basic Information
Title: Molecular biology Code: E9002
Credit Hours: 1
Lecture: 1 hour/w (10w) Practical: 1 hour/w (10w) SDL
Total: 10 theoretical and 10 practical hours
Coordinator
Head of the department
B - Professional Information
1. Course Aims:
The course aims to provide a thorough understanding and practical experience
of molecular biology as it applies to infectious agents including:
a) Introducing the students to the basics of molecular biology and
biotechnology.
b) Training of the students on the different molecular biology techniques.
c) Application of such techniques in taxonomy, diagnosis, epidemiology and
chemotherapy of infectious organisms.
d) Equipping of the students with the specialized knowledge and skills
necessary for a research careers that demand knowledge of molecular
biology.
42
2. Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the course the candidate will be able to:
a1) Understand the structure, function and organization of microbial
genomes.
a2) Describe the main principles of methods for preparation and extraction
of DNA and RNA.
a3) Understand the main principles and methods of DNA amplification
(PCR, RT-PCR, Real-time PCR, etc.)
a4) Understand the principles and methods of DNA sequencing.
a5) Describe the main principles of DNA and RNA blotting
a6) Understand the concepts of recombinant DNA technology
a7) Understand the applications of molecular biology techniques in the
diagnosis, taxonomy, species and strain differention of
microorganisms.
.a8) Understand the applications of molecular biology techniques in
studying drug resistance, and vaccine and drug development.
a9) Understand the principle of proteomics and microarrays.
b) Intellectual skills
By the end of the course the candidate will be able to:
b1) Design primers from a known gene sequence.
b2) Differentiate between microorganism by RFLP and RAPD-PCR.
b3) Interpret the results of diagnostic molecular assays and discard false
results.
c) Professional and practical skills:
By the end of the course, students will be able to:
c1) Apply safety measures in the laboratory.
c2) Apply methods to prevent contamination of the lab and equipments.
c3) Follow proper method of disposal of biohazardous samples
(infectious, carcinogenic, etc.).
c4) Extract DNA and RNA.
c5) Perform PCR.
d) General and transferable skills:
By the end of the course the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Show willing and motivations for self learning and continuous
improvement.
d4) Represent data efficiently.
d5) Search gene and protein database.
d6) Use molecular biology software and vsit parasite genomes websites.
43
4- Course content:
Basic principles in molecular
biology
No. of hours
L (1h) T P SDL
1- Nucleic acid structure and
organization
3 √
2- Cell cycle, DNA replication and
repair
2
3- RNA transcription and
processing
2 √
4- Regulation of gene expression
2
5-The Genetic code, mutation and
protein synthesis
2
6- Recombinant DNA technology 2
7- Techniques of genetic analysis
-Extraction of DNA & RNA
- PCR & RT-PCR
- DNA electrophoresis
- Blotting techniques
- RFLP
- Microarray
6
8- Genetic variation &
DNA finger printing
2 2
13-Ethical, Legal, and Social
implications of genetic knowledge
2
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills
4.2 Practical exams to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills.
Marks distribution
Written: 30 Marks Practical: 15 Marks Oral: 5 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books)
a) Molecular Cloning: A Laboratory Manual (Third Edition) 2001:
Joseph Sambrook, David Russell (Eds.). Cold Spring Harbor
Laboratory Press.
44
b) PCR “The Basics” (Second Edition) 2006: M. J. McPherson and S. G.
Muller, Taylor and Francis.
c) A-Z of Quantitative PCR (IUL Biotechnology, No. 5) (IuL
Biotechnology Series) 2004: Stephen A., Bustin International
University.
d) Fundamental Molecular Biology by Lizabeth A. Allison
e) Essentials of Molecular Biology by George M. Malacinski.
f) Molecular Biology: Genes to Proteins by Burton E. Tropp.
g) Short Protocols in Molecular Biology (2 volume set) by Frederick M.
Ausubel, Roger Brent, Robert E. Kingston, and David D. Moore.
h) Basic Techniques in Molecular Biology (Springer Lab Manuals) by
Stefan Surzycki.
i) Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson,
Julian Lewis, and Martin Raff.
j) Molecular Cell Biology by Harvey Lodish, Arnold Berk, Chris A.
Kaiser, and Monty Krieger.
5.3- Recommended Books
a) Molecular Cloning: A Laboratory Manual (Third Edition) 2001:
Joseph Sambrook, David Russell (Eds.). Cold Spring Harbor
Laboratory Press.
b) Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson,
Julian Lewis, and Martin Raff.
c) Molecular Cell Biology by Harvey Lodish, Arnold Berk, Chris A.
Kaiser, and Monty Krieger.
5.4- Periodicals, Web Sites, etc
a) Pubmed: http://www.ncbi.nlm.nih.gov/
b) The Ensembl genome databases for vertebrates and other eukaryotic
species http://www.ensembl.org/index.html
c) Expert Protein Analysis System Proteomics server
http://www.expasy.org/
d) Bioinformatics search http://www.bioinformatik.de
e) DNA from the beginning: http://www.dnaftb.org/dnaftb/
f) Protein Data Bank http://www.rcsb.org
g) Phylogenetic Tree Prediction
http://www.genebee.msu.su/services/phtree_reduced.html
45
2. Course specification for Immunology
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: Minor.
Department offering the program: Parasitology Department
Department offering the course: Microbiology and Immunology Department
Academic year / Level: First year/ second semester
Date of specification approval ……………………………………..
A- Basic Information
Title: Immunology Code: E9031
Credit Hours: 1
Lecture: 1 hour/w (10w) Practical: 1 hour/w (10w) SDL
Total: 10 theoretical and 10 practical hours
Coordinator
Head of the department
B - Professional Information
1. Course Aims:
The course aims to provide basic knowledge and understanding, and practical
experience of immunology to infectious agents including:
a) Basic knowledge and understanding of the immunity to microbes.
b) Training of the students on the immunologic assays used for the diagnosis
of microbial infection.
c) Training of the students on the techniques for assessing immune response
to pathogens.
2. Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the course the candidate will be able to:
a1) Define immunity, immune system and immune response.
a2) Know the types of immunity, components, phases and characteristics
of the adaptive immune response.
a3) Know the tissues and cells of the immune system.
a4) Know the nature of immunogen, haptens and adjuvants, and the
factors responsible for immunogenicity.
a5) Know the structure and function of the soluble mediators of immunity;
cytokines and antibodies.
a6) Understand the mechanisms and effector functions of cell mediated
immunity.
a7) Understand the mechanisms and effector functions of humoral
immune response.
46
a8) Understand the immunological mechanisms underlying:
- Immune regulation and immunologic tolerance,
- Inflammation,
- Protection against microbial disease,
- Hypersensitivity or allergic reactions,
- Congenital and acquired immunodeficiencies.
a9) Understand the basics of antigen-antibody reactions and their
applications in diagnosis of infections.
b) Intellectual skills
By the end of the course the candidate should be able to:
b1) Differentiate between the two types of immunity.
b2) Differentiate between the two limbs of the adaptive immunity.
b3) Predict the type of the immune response to intracellular and
extracellular pathogens.
b4) Interpret immunological reports.
b5) Correlate the immune response and pathogenecity.
c) Professional and practical skills:
By the end of the course the candidate will be able to:
c1) Apply safety measures in the laboratory.
c2) Perform and interpret antigen-antibody assays as agglutination,
precipitation, enzyme immunoassays, immunofluorescence and
immunoblotting.
d) General and transferable skills:
By the end of the course the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Show willing and motivations for self learning and continuous
improvement.
d4) Represent data efficiently.
5- Course content:
Topics No of hours
Lecture Practical
Humoral and cellular immune response 2
Cytokines as modulators of immune response
Type 1 and Type 2 helper cells
2
Immunity to microbes 2
Hypersensitivity reactions 2
Immunodeficiency 2
Antigen-antibody reactions 8
In vitro assessment of cellular function 2
47
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills.
4.2 Practical exams to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills.
Marks distribution
Written: 30 Marks Practical: 15 Marks Oral: 5 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books)
a) Basic Immunology by Abul K. Abbas and Andrew H. Lichtman (3rd
edition).
b) Roitt's Essential Immunology by Peter Delves, Seamus Martin,
Dennis Burton, and Ivan Roitt.
c) Immunology: A Short Course by Richard Coico and Geoffrey
Sunshine.
d) Cellular and Molecular Immunology: by Abul K. Abbas, Andrew
H. Lichtman (2003) (5th
edition).
e) Immunology for Medical Students by Roderick Nairn PhD and
Matthew Helbert.
f) Immunobiology, The Immune System in Health and Disease
(2005), 6th Edition Charles A. Janeway, Paul Travers, Mark
Walport and Marl J. Shlomchik Churchill Livingstone, New York.
5.3- Recommended Books
a) Basic Immunology by Abul K. Abbas and Andrew H. Lichtman (3rd
edition).
b) Cellular and Molecular Immunology: by Abul K. Abbas, Andrew
H. Lichtman (2003) (5th
edition).
c) Immunology, (2006), 7th Edition, David Male, Jonathan Brostoff,
David B Roth, Ivan Roitt. Mosby, London.
5.4- Periodicals, Web Sites, etc
a) Egyptian Journal of Immunology
b) Parasite Immunology
c) Infection and Immunity
d) Journal of Immunology
e) Pubmed: www.ncbi.nlm.nih.gov
f) Microbiology, Immunology and Parasitology course online “South
Carolina University: www.med.sc.edu:85/book/parasit-sta.htm
48
3. Course specification for Vector Biology
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: Minor
Department offering the program: Parasitology Department
Departments offering the course:
Parasitology Department Faculty of Medicine, Ain Shams University
Academic year / Level: First year/ second semester
Date of specification approval ……………………………………..
A- Basic Information
Title: Vector biology Code: E9032
Credit Hours: 1
Lecture: 1 hour/w (10w) Practical: 1 hour/w (10w) SDL
Total: 10 theoretical and 10 practical hours
Coordinator
Head of the department
B - Professional Information
1. Course Aims:
The course aims to provide basic knowledge and understanding of:
a) Vector behaviour and ecology and vector-parasite interactions.
b) How these features impact on the epidemiology and control of vector-
borne diseases.
c) The importance of accurate vector identification in surveillance and
control.
d) Appropriate sampling methods for the major groups of vectors.
e) Practical entomological techniques used in vector identification and
incrimination, and in the study of vector competence, behaviour and
ecology.
f) Control of vectors.
2. Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the course the candidate will be able to:
a1) Realize the importance of arthropods in causing and transmitting
microbial infections.
a2) Understand vector bionomics including:
- Breeding places and habits,
- Feeding habits, biting behaviour and adaptation of mouth parts to
the feeding habits, blood and host preference (specificity),
- Flight range,
- Swarming, mating behaviour, and oviposition,
49
- Hibernation and overwintering.
a3) Understand the life cycle and development of arthropods.
a4) Know the modes of infections and transmission of pathogens by
arthropods.
a5) Describe the life cycle of the parasite inside their vector.
a6) Understand parasite vector interaction.
a7) Explain the disease caused by arthropods.
a8) Understand the relation between arthropods and allergy.
a9) Understand the vector immunity to pathogens.
a10) Understand the methods of vector control; physical, chemical,
biological and genetic control.
a11) Describe the side effects of insecticides.
a12) Understand the methods of vector trapping (light traps, sticky traps,
tsetse traps).
a13) Understand the methods of detection of pathogens inside arthropods
(incrimination techniques) as dissection of infected vectors, ELISA
and PCR.
b) Intellectual skills
By the end of the course the candidate should be able to:
b1) Correlate the bionomics with methods of control.
b2) Correlate the distribution of diseases with geographical distribution of
their vectors.
b3) Differentiate between the modes of transmission of pathogens by
arthropods.
c) Professional and practical skills:
By the end of the course the candidate will be able to:
c1) Indentify arthropod through morphological keys.
c2) Collect (trap) vectors from their breeding places.
c3) Apply the required precaution to prevent self infection while
collecting vectors.
c4) Isolate house dust mites from dust samples
c5) Dissect arthropods to detect pathogens.
c6) Prepare antigen from arthropods and use them in immunological
assays and skin testing.
c7) Control of arthropods by using suitable physical, chemical and
biological methods.
d) General and transferable skills:
By the end of the course the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
50
d3) Show willing and motivations for self learning and continuous
improvement.
d4) Represent data efficiently.
3- Course contents:
Topics No of hours
Lecture Practical SDL
Role of arthropods in disease
transmission
2
Vector bionomics 4
Parasite vector interaction 2
Vector control 2
Vector identification keys 2
Collection of vectors 2
Isolation of mites from house dust 2
Preparation of antigens from
arthropods
4
Methods of detection of
pathogens inside vectors
√
Vector immunity to pathogens √
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills.
4.2 Practical exams to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills.
Marks distribution
Written: 30 Marks Practical: 15 Marks Oral: 5 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books)
a) Clinical Parasitology: by Craig, Faust , Beaver (Lippincott Williams
& Wilkins, US; 9th edition).
b) Manson's Tropical Diseases: by Cook and Zumla (Saunders Ltd.; 21st
edition).
c) Foundations of Parasitology: by Schmidt and Roberts (Times Mirror /
Mosby College Publishing).
51
d) Foundations of Parasitology: by Roberts and Janovy (McGraw-Hill
Higher Education; 7th
edition).
e) Human Parasitology: by Bogitsh, Carter, Oeltmann
f) Parasitology and Vector Biology: by Marquardt, Demaree (Grieve
Academic Press; 2 edition).
g) Biology of Parasitism: by David, Tschudi, Pearce (Kluwer
Academic Publishers, 2000).
5.3- Recommended Books
a) Parasitology and Vector Biology: by Marquardt, Demaree (Grieve
Academic Press; 2 edition).
b) Manson's Tropical Diseases: by Cook and Zumla (Saunders Ltd.;
21st edition).
5.4- Periodicals, Web Sites, etc
a) Egyptian Journal of Parasitology
b) American Journal of Tropical Medicine and Hygiene
c) Transaction of Royal Society of Tropical Medicine and Hygiene
d) WHO: www.who.int
e) Parasitology Division, Center of Disease Control: www.cdc.dpdx.gov
f) Pubmed: www.ncbi.nlm.nih.gov
g) London School of Hygiene and Tropical Medicine “Intensive Course
in Vector Biology” www.lshtm.ac.uk/dcvbu/vbi.htm
h) TDR, a Special Programme for Research and Training in Tropical
Diseases: www.who.int/tdr/
i) The World Organisation for Animal Health (OIE):
http://www.oie.int/
52
4. Course specification for Biostatistics
University: Ain Shams Faculty: Medicine
Program(s) on which the course is given: Master of Science in Parasitology
Major or minor element of programs: Minor
Department offering the program: Parasitology Department
Departments offering the course: Community, Environmental and Occupational
Medicine
Academic year / Level: First year/ second semester
Date of specification approval ……………………………………..
A- Basic Information
Title: Biostatistics Code: E9009
Credit Hours: 1
Lecture: 1 hour/w (10w) Practical: 1 hour/w (10w) SDL
Total: 10 theoretical and 10 practical hours
Coordinator
Head of the department
B - Professional Information
1. Course Aims:
To enable the candidate to plan, conduct, analyze and interpret the results of a
research in his specific field. This course unit introduces the application of
statistical ideas and methodology to medical research.
2. Intended learning outcomes (ILOs):
a) Knowledge and Understanding
By the end of the course the candidate will be able to:
a1) Know the definition and types of variables.
a2) Understand the basics of descriptive statistics as mean, median,
standard deviation and standard error.
a3) Know the concept of normal distribution and confidence of interval and
hypothesis testing.
a4) Understand the basics of probability and significance tests.
a5) Understand the basic of analysis of categorical data, comparing of
means and proportions and analysis of variance (ANOVA).
a6) Understand the concepts of correlation and regression
a7) Understand the applications of transformation and non-parametric
methods.
a8) Know sampling methods, calculation of required sample size and
sources of statistical bias and errors.
a9) Know the computer software used for statistical calculation.
b) Intellectual skills
By the end of the course the candidate will be able to:
53
b1) Interpret the results of the statistical techniques.
b2) Select the appropriate statistical analysis test for a given data.
b3) Select the appropriate non-parametric when required.
b4) Detect sources of confounding and errors.
c) Professional and practical skills:
By the end of the cours, the candidate will be able to:
c1) Calculate frequency, mean, median, standard deviation and standard
error.
c2) Analyze a single mean (z-test).
c3) Compare means and proportion using parametric tests (t, f, ANOVA,
Chi-squared tests) and their non-parametric equivalents.
c4) Interpret the significance of the above test.
c5) Determine the relationship between different variables using
correlation coefficient and linear regression.
c4) Represent data by tabulation and suitable diagrams as bar, pie, and
linear charts.
c5) Use statistical software as SPSS an EPI-INFO, EXCEL, STATA, etc.
d) General and transferable skills:
By the end of the course the candidate will be able to:
d1) Show respect to colleagues and senior staff.
d2) Cooperate with colleagues, administrative staff and work in team.
d3) Show willing and motivations for self learning and continuous
improvement.
3- Course contents:
Topics No of hours
Lecture Practical
Introduction to medical statistics and its
uses
1
- Types of variables and Descriptive
statistics
- Calculation of mean, median, standard
deviation and standard error.
1
2
Graphic presentation of data 2
Introduction to probability theory and
rules
1
Confidence interval of means and
proportions
1
Comparing of means, proportions and
analysis of variance (t, f, z tests, Anova)
2 3
Correlation and regression 2
54
Non-parametric tests 1
Sampling methods and sample size 1
Use statistical software as SPSS an EPI-
INFO, EXCEL, STATA, etc.
3
4 - Student Assessment Methods
4.1 Written exams (Essay, MCQ, interpretation) to assess knowledge,
understanding and intellectual skills
4.2 Practical exercises to assess professional and intellectual skills.
4.3 Oral exams to assess knowledge, understanding, intellectual and general
transferable skills.
Marks distribution
Written: 30 Marks Practical: 15 Marks Oral: 5 Marks
5- List of References
5.1- Course Notes (paper and / or electronic)
5.2- Essential Books (Text Books)
a) Statistics in Clinical Practice. avid Coggon. BMJ Books. 2nd
edition
2003
b) Basic and Clinical Biostatistics (Lange Basic Science) by Beth
Dawson, Robert Trapp, Beth Dawson, and Robert Trapp
c) Epidemiology, Biostatistics and Preventive Medicine by James F.
Jekel, David L. Katz and Joann G. Elmore
5.3- Recommended Books
Handbook of Epidemiology. Springer 2005
5.4- Periodicals, Web Sites, etc
a) http://www.brettscaife.net/statistics/introstat/
onlinestatbook.com/rvls/
b) http://www. Epidemiolog.net
c) http://www.shef.ac.uk/scharr/spss/
55
V- General Information
1 – Monitoring Of Training and Submission of Training Reports
You must keep proper and updated records in your logbook to reflect the
activities encountered in your training. Your logbook must be duly endorsed by an
authorized signatory at the end of each semester.
You will be continuously assessed by your supervisors, in consultation
with head of department. An assessment will be submitted within 2 weeks of
completion of each semester.
2 - Miscellaneous Information:
Injury and/or Blood or Body Fluid Exposure:
During regular working hours, you should immediately report an exposure incident
to Head of the Department. If exposure occurs after regular working hours or
during a weekend or holiday; please call the ----------------------------------------. For
injury, please report to the Emergency Department.
Please also be sure to inform the supervisors of an exposure incident and/or
injury.
3 - Action Completion of Clinical Training
Once all training sessions are completed the log book should be signed by the senior
supervisor and the head of the department and then should be submitted to post
graduate Secretariat.
4- Reference
The Training Guide is available at the post graduate Secretariat and could be
downloaded from the following website is
---------------------------------------------------------------
VI – Your log book
1- Introduction
The aim of this book is to give you a guide to the expectations for each item. It will
be a guide for both you and your teachers to what you should be seeing and doing.
It will give you a list of the important topics that you should think about and should
be covered in:
1. Laboratory
2. Seminars
56
3. Tutorials
4. Self-directed learning (SDL)
Remember
This document is only a guide. It is not an exhaustive list. It is not just a checklist
to score points. It is a guide to encourage you to read and learn more. This book is
for your benefit. It will form a record of your clinical training and experience.
2 - Supervisors
1. Prof. Dr. Head of the department
2. Prof. Dr.
3. Prof. Dr.
4. Prof. Dr.
5. Prof. Dr.
3–Tables for Training Records
The candidate will record the details and date of each activity, and the authorized
staff member signature.
Candidates are required to fulfill 75% of the listed activities in order to be eligible
for the exam entry. The minimum number required for each activity = 75%. You
are free to attend more and record your extra attendance.
Weekly Department Plan
Day /time Saturday Sunday Monday Tuesday Wednesday Thursday
Theoretical 10-13
Practical 8-12
Seminar 10-12
Working in
Parasitology
Diagnostic
unit
9-13 9-13 9-13 9-13 9-13 9-13
Monthly activity: Thesis attendance
Yearly activity: Annual Conferences
57
Seminars Attendance
(NB. Minimum number required is 5)
No. Date Place Topic Supervisor
Signature
1
2
3
4
5
The student should submit a report on the seminar.
Conferences Attendance
(NB. Minimum number required is 2)
No. Date Place Topic Supervisor
Signature
1
2
The student should submit a certificate of attendance or participation.
58
Thesis Attendance
(NB. Minimum number required is10)
No Date Place Title of the thesis Supervisor
signature
1
2
3
4
5
6
7
8
9
10
The student should submit a report on the thesis discussion.
.
59
Update Articles Presentation
(NB. Minimum number required is 2)
No. Date Place Topic Supervisor
Signature
1
2
Stool Examination for Parasites by Direct Smear Method
(NB. Minimum number required 100*)
No. Date Semester Place Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
6
7
8
9
10
11
60
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
61
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
62
52
53
54
55
56
57
58
59
50
61
62
63
64
65
66
67
68
69
70
71
63
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
64
92
93
94
95
96
97
98
100
At least 50 with score A.
Urine Examination for Parasites
(NB. Minimum number required 50*)
No. Date Semester Place Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
6
7
8
65
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
66
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
67
49
50
At least 25 with score A.
Stool Concentration Techniques
(NB. Minimum number required is 20*)
No. Date Semester Place Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
68
16
17
18
19
20
At least 10 with score A.
Cultivation of the Larval Stages of Nematodes
(NB. Minimum number required is 5*)
No. Date Semester Place Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
At least 3 with score A.
69
Blood Examination for Parasites
(NB. Minimum number required is 15*)
No. Date Semester Place Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
At least 8 with score A.
70
Staining of Stool Specimens for Detection of Parasites
(NB. Minimum number required is 10*)
No. Date Semester Place Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
6
7
8
9
10
At least 5 with score A.
71
Serodiagnosis of Parasitic Infections
(NB. Minimum number required is 5*)
No. Date Semester Place Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
At least 3 with score A.
Preparation of Preserved stool samples
(NB. Minimum number required is 5*)
No. Date Semester Specimen Score
(A, B, C, D)
Points Supervisor
Signature
1
2
3
4
5
At least 3 with score A.
72
- Activities should be distributed over the 4 semesters
- Activities will be evaluated by the supervisors using check lists
- Activities will be scored and graded according to the proficiency of
performance into:
1. A: Excellent performance: 85-100 % of the score
2. B: Very Good performance: 75-84 % of the score
3. C: Good performance: 65-75 % of the score
4. D: Unacceptable and should be repeated
73
4 - Log book preview
The candidate logbook will be reviewed and patients seen/ skills performed
summarized by diagnosis groups during the semester evaluation and at the end of
the course in the table below. This reflects the number of activity done by
category. (According to each degree) The results of this review will be totaled in
the summary chart below.
Summary
Semester 1st 2
nd 3
rd 4
th Total
Activity No No No No
Seminars attendance (5)
Conferences attendance (2)
Thesis discussion attendance (10)
Update article presentation (2)
Stool examination for parasites (100)
Urine examination for parasites (50)
Stool Concentration techniques (20)
Cultivation of the Larval Stages of
Nematodes (5)
Blood examination for parasites (25)
Staining of stool specimens for
detection of parasites (10)
Serodiagnosis of parasitic infections (5)
Preparation of preserved stool samples
Supervisor signature
VII - Head of Department Approval for the Exam Entry
__________________________________________________________________
____________________________________________
__________________________________________________________________
____________________________________________
74
VIII – Thesis Follow up
انتاريخ/ انتقزيز اننصف انسنىي نعاو /
عن انطانب /
انقيد ندرجة ) ياجسيتز / اندكتىراة (
بقسى /
تقزيز انسادة االساتذة انشزفين
بدأ جع انادة انعهية و كتابة انقدية
قطع شىطا يحدودا
أوشك عه اإلنتهاء
إنته ين انجع
بدأ انجزء انعه
قطع شىطا يحدودا
أوشك عه اإلنتهاء
إنته ين انتحهيم
بدأ يناقشة اننتائج
قطع شىطا يحدودا
أوشك عه اإلنتهاء
إنته ين انتحزيز
بدأ انزاجعة اننهائية يع انشزف
دوداقطع شىطا يح
أوشك عه اإلنتهاء
إنتهت تايا
إستزار قيد انطانب رأي انسادة انشزفين
يد انقيد
شطب قيد انطانب
نعى تى تشكيم نجنة انناقشة
ال
تاريخ انتشكيم
/ /
يد / شطب انقيد
وكيم انكهية تىقيع انسادة انشزفين
75
76
IX – Evaluation Forms
Evaluation Form (at the end of each semester) To be completed at -------------------------------------
Candidate
Supervisor
Location
Aim of training
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Agreed educational objectives and timescale in which objectives should be
achieved.
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Candidate
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Supervisor
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Date of next meeting
Signed by candidate Signed by Supervisor
Date
77
78
Degree Program Evaluation Form by the Candidate
To be completed at the end of your degree.
Please consider each pair of statements and decide which most clearly reflects your
view and tick one box or answer the question.
I. Individual Information
1. Are you a graduate of ASU?
yes no to some degree
2. Year and semester when studies began:
II. General Questions
1. What are the advantages/disadvantages of the general study environment at the
University ASU?
2. What were your expectations when you applied to the degree?
3. Do you feel that the degree program prepares you well for your future studies or
employment according to the demands and expectations of those institutions?
Yes No To some degree
4. Has the time limit of the program (two or three academic years) caused you any
difficulties or inconveniences?
Yes No To some degree
III. Structure of Degree Program
1. Did you receive enough guidance in planning your study schedule in the
beginning of the program?
Yes No To some degree
2. What were the main difficulties in the planning of your study schedule?
3. What is your general opinion on the structure of the degree program?
79
4. In your opinion, does the degree program offer a good balance of lectures,
seminars, conferences, and book exams?
Yes No To some degree
a) General Studies
i) Do you feel that you have received enough guidance on academic writing?
Yes No To some degree
ii) Do you feel that you have acquired sufficient knowledge on research skills (eg.
quantitative and qualitative research methods)?
Yes No To some degree
b) Courses
i) Have you had some special difficulties in completing some of the courses?
Please specify.
ii) Has there been a sufficient variety of courses offered for your optional studies?
Yes No To some degree
iii) Have you received enough guidance for the preparation of your thesis?
Yes No To some degree
IV. Concluding Points
1. Did the degree program meet your expectations?
Yes No To some degree
2. What aspects of the degree program do you particularly like?
3. What aspects of the degree program do you particularly dislike?
4. What are your suggestions on how to improve the program?
Thank you!