Genealogical Tests Using DNA

7/23/2019 Genealogical Tests Using DNA

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Genealogy

Using DNAAnalytics

GRP 7: ASUNCION, MAGLANQUE, MAS, VELASCO


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GENEALOG

Int!o to


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"

Genealogy

$a#ily %is St&'y o$ an' t!acit%ei! line%isto!y


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"esting

A (ay $o! )eo)le inte!efamily historyto go *t%ey can lea!n $!o# !ela$!o# %isto!ical 'oce

Tests of comparison

in'i+i'&als DNA to ot%et%e sa#e lineage o! to %isto!ic et%nic g!o&)s


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To know more about a persons histofamilies

P!o+i'e cl&es a*o&t a )e!sons ancesto!s an'

!elations%i)s *et(een $a#ilies

A combination of these tests from mapeople can be used to track historiespopulation

Mig!ation-#i.ing o$ )eo)le g!o&)s


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in+ol+e'P!oce'&


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S"EP /: Submission of DNA S

C%ee0sc!a)ing

1*&ccals(a*2

S)it


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S"EP 3: Sa#)le is t%en #aile' toTesting Lab


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Genealogical

"est


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"y)es o$ Genealogical "ests

/4 A&toso#al (atDNA)

34 Mitoc%on'!ial DNA (mtDNA)

64 C%!o#oso#e (Y-DNA)


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/4 A&toso#al"est (atDNA)Autosomes

- 33 #atc%e' )ai!s o$c%!o#oso#es

Autosomal DNA

-in%e!ite' $!o# *ot%)a!ents !an'o#cont!i*&tions $!o# t%ei!)a!ents, g!an')a!ents,an' so on


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#ay *e ta0en *yeit%e! a maleo! afemale

/4 A&toso#al "est (atDNA)

Used for:

!elati+e connalong any *!yo&! $a#ily t

X connection *ac0

X (%ic% *!anc$a#ily t%e #


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A&toso#al "est 1atDNA2: 8o( 'oes


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The smaller the fragment of shared autoDNA, generally the further back the conyour family tree

Relation Percentage of

aDNA Sharing()

Pa!ents an'Si*lings

;

G!an')a!ents,A&nts-Uncles,8al$si*lings

3


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"lose #s$

Distant


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Data*ases o$ Co#)anies O?e!A&toso#al DNA "ests


18/42%amil& %in!er


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Ancestr& DNA


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Relati#e %in!er


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34 Mitoc%on'!ial"est (mtDNA)'itochon!ria-

8as its o(n DNAmaternal DNA

'itochon!rial DNAin%e!ite' e.cl&si+ely$!o# o&! #ot%e!s$ollo(s an &n*!o0en#ate!nal line


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#ay *e ta0en *yeit%e! a maleo! a

female

Used for:

'i!ect #ate!n

+e!i$ying t%e o$ a co##on

ancesto! only &se$&l $o

'ete!#ining

#ate!nal anc

34 Mitoc%on'!ial"est (mtDNA)


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34 Mitoc%on'!ial"est (mtDNA)#tDNA lineages

can *e g!o&)e'toget%e! in ala!ge mtDNAtree

Eac% *!anc% o$t%is t!ee #ay

%a+e a specifcgeographicdistribution t%at%el)s in location


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Mitoc%on'!ial "est 1#tDNA2: 8o( '(o!09


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/4 o&! #tDNA !es&lts

!e$e!ence se@&ence Cambridge Reerence (CRS)

34 o&! s)ecic%a)loty)ea set o$ closely lin0e' alleles t%in%e!ite' as a &nit

People with the same haplotype shacommon ancestor somewhere in the ma

line

Compared to

Determine

Lie this


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Alice

Betty

Cecily

Dotty

Erica

CRS

Beulah

Carol

Dorcas

Elizabeth

16519C 263G

315.1C

Ancestral 'tDNA PatternSample


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!mtDNA(*R+), *asic #ate!nal ancest!y*ac0 %&n'!e's o$ t%o&san's o$ yea!s

"!mtDNAPlus (*R+.), #o!e !ene' geoo!igins 'ata $o! #ate!nal line in t%e last 3,;

0$mtDNA #ull $enomic %e&uence, &n'e!st%e genealogy, %isto!ic, an' ancient ancest'i!ect #ate!nal line

0 le#els of mtDNAtests,


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ample mtDNA result

0 Y DNA T t


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0$ Y-DNA Test

Y-chromosome- Se. c%!o#oso#e t%at

is !es)onsi*le $o!#aleness 1all #ales%a+e one c%!o#oso#e2

- co)ies a!e )asse''o(n 1+i!t&ally2&nc%ange' $!o#

$at%e! to son eac%

0 Y DNA T t


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0$ Y-DNA Test

'#or (ales )nly!


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1DNA "est2: 8o( 'oes it (o!09

/ DNA t t lt


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/4 o&! DNA test !es&lts

n*e!s !e)!esent t%e !e)eats 1st&tte!s2 $eac% o$ t%e teste' #a!0e!s on t%e c%!o#

34 o&! s)ecic DNA%a)loty)e

$o! )ate!nal line%ame as, or e*tremely similar to, all o

males who ha+e come before you on y

Contains a gene!al %a)log!st!ing o$ n*e!s

Determine

Lie this

%amil&Tree, Y DNA


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%amil&Tree, Y-DNATest


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A&'ience

'aternal origin tests

-e.act #atc%ing on t%e #tDNA $&ll se@&enc

1eographical origin tests-atte#)t to #eas&!e an in'i+i'&alBs #i.e' g

%e!itage *y i'enti$ying )a!tic&la! #a!0e!s

i$e$US, Nati+e A#e!ican, A$!ican, Mel&ngeoCo%ani#, E&!o)ean, 8in'& Ancest!y

raphical origin tests (1enographic Pro2ect


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raphical origin tests (1enographic Pro2ect


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enets

I#)o!tance

an'


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+e!i$y e.isting !esea!c%es

Esta*lis% t%e !elation o$ t(o s&!na#e +a!iants

P!o+i'e locations $o! $&!t%e! genealogical

!esea!c%es

8el) 'ete!#ine t%e ancest!al %o#elan'

8el) 'isco+e! li+ing !elati+es

Positi#e results ma& ,


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Positi#e results ma&, Con!# o! 'eny s&s)ecte' connections

*et(een $a#ilies P!o+e o! 'is)!o+e t%eo!ies !ega!'ing anc


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Do(nsi'e9


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"%e ne(e! genetic admi*ture tests

t%e c%ance o$ #isi'enti$ying ancest!al gt%ese genealogy tests #ay *e )e!cent

SNPS t%at 'isting&is% nationalities $!o# eac%

a!ent t%at (ell esta*lis%e' $o! so#e nationalClai# to i'enti$y t%e ancest!al co#)onents'i?e!ent )o)&lations4

Disa!#antages


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Po(ell, 4 13;/24 A&toso#al DNA "esting $o! Genealo

$!o#%tt):--genealogy4a*o&t4co#-o'-'naFgenetics-)-a&t

Genetic Genealogy, 8isto!y an' P!e%isto!y, an' DNAAncest!y "!acing

Donal' N4 ates, P%4D4%at Can I Lea!n

Genealogical Tests Using DNA

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