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    DeanOrnish

    DeanOrnish

    MikeMilken

    MikeMilken

    WilliamNelson

    WilliamNelson

    DCDC

    Alternative Medicine Joins the MainsAlternative Medicine Joins the Mains

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    Consciousness Creates ReaConsciousness Creates ReaCo-create andreflect eachother,interdependentlyco-arise, are atangledhierarchy.

    They aresynchronisticallyarising emergentproperties thatco-emerge

    depending on thelevel of vibration

    of individual andcollectiveconsciousness.

    Co-create andreflect eachother,interdependently

    co-arise, are atangledhierarchy.

    They aresynchronisticallyarising emergentproperties thatco-emergedepending on thelevel of vibration

    of individual andcollectiveconsciousness.

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    5 Breakthroughs for the 5 Breakthroughs for the

    Your body is a process, not a structure.Your body is a process, not a structure.

    Your body is an energy field.Your body is an energy field.

    Your can turn your genes on and off.Your can turn your genes on and off.

    You can change your relationship with timYou can change your relationship with tim

    Awareness is the key to transformation aAwareness is the key to transformation a

    reinventing the body.reinventing the body.

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    Resurrecting the SoulResurrecting the SoulYour life is a flow of effortless spontaneity.Your life is a flow of effortless spontaneity.

    Love is the soulLove is the souls only motivations only motivation

    You have unlimitedYou have unlimited imaginationimagination and creativityand creativity

    You invite Grace in your lifeYou invite Grace in your life

    You choose evolution over entropy.You choose evolution over entropy.

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    Our health care systemreally a disease care systOur health care systemreally a disease care syst

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    $2.1 trillion spent last year

    medical care = 16.5% of GD

    95% spent to treat disease aft

    had already occurred

    $2.1 trillion spent last year

    medical care = 16.5% of GD

    95% spent to treat disease aft

    had already occurred

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    If we want to make health c

    available to the 48 millionAmericans who dont have it,need to address the underly

    causes

    of disease.

    If we want to make health ca

    available to the 48 millionAmericans who dont have it,need to address the underly

    causes

    of disease.

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    Cardiovascular diseases kill m

    people worldwide each yethan all other illnesses

    combined.

    Cardiovascular diseases kill m

    people worldwide each yeathan all other illnesses

    combined.

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    In a study of over 30,000 pati

    heart disease was completepreventable

    for almost 95%

    of

    just by changing diet and life

    Yusuf S et al. Lancet. 2004 Sep 11;364(9438):937-52.

    In a study of over 30,000 pati

    heart disease was completepreventable

    for almost 95%

    of

    just by changing diet and lifes

    Yusuf S et al. Lancet. 2004 Sep 11;364(9438):937-52.

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    COURAGE TRIAL

    Angioplasty did not reduce

    risk of death, heart attackother major cardiovascul

    events.

    --Boden WE et al. N Engl J Med 2007;356:1-14.

    COURAGE TRIAL

    Angioplasty did not reduce

    risk of death, heart attack,other major cardiovascul

    events.

    --Boden WE et al. N Engl J Med 2007;356:1-14.

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    In 2006, 448,000 coronary byoperations were performed cost of more than $44 billio

    In 2006, 448,000 coronary byoperations were performed cost of more than $44 billio

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    Coronary bypass surgery prolife in only 2-3% of those w

    receive it.

    .

    --Caracciolo EA et al.Circulation. 1995;91(9):2325-34

    Coronary bypass surgery prolife in only 2-3% of those w

    receive it..

    --Caracciolo

    EA et al.Circulation. 1995;91(9):2325-34

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    Dangerous, invasive, expenand ineffective

    Dangerous, invasive, expenand ineffective

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    Coronary heart disease is not

    preventable, it is usuallyreversible

    by changing dieand lifestyle.

    Coronary heart disease is not

    preventable, it is usuallyreversible

    by changing dieand lifestyle.

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    Optimal Lifestyle ProgramOptimal Lifestyle Program

    Nutrition

    Stress managementModerate exercise

    Psychosocial support

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    The primary determinant o

    improvementwas the degree of lifestyle cha

    The primary determinant o

    improvementwas the degree of lifestyle cha

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    Scaleability

    & Cost EffectivenScaleability

    & Cost Effectiven

    Three demonstration projectsMore than 3,000 patients

    Greater changes in diet and lifestyle, larg

    improvements in risk factors and quality o

    and bigger cost reductions than have ever

    been reported in an ambulatory group of

    Three demonstration projects

    More than 3,000 patients

    Greater changes in diet and lifestyle, larg

    improvements in risk factors and quality o

    and bigger cost reductions than have ever

    been reported in an ambulatory group of p

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    1. The Multicenter Lifestyl

    Demonstration Project

    1. The Multicenter Lifestyl

    Demonstration Project

    Almost 80% of 333 patients who

    eligible for bypass surgery or angwere able to safely avoid it.

    Ornish D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration PCardiology. 1998;82:72T-76T.

    Koertge J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality of life incoronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Card

    Almost 80% of 333 patients who w

    eligible for bypass surgery or angwere able to safely avoid it.

    Ornish D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration PCardiology. 1998;82:72T-76T.

    Koertge J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality of life incoronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Card

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    2. The Highmark Blue Cross Bl

    Shield Demonstration Project:Cost Comparisons After 3 Year

    2. The Highmark Blue Cross Bl

    Shield Demonstration Project:Cost Comparisons After 3 Year

    Experimental Group (CAD) (N=75) Baseline vs. 3 year average = 8.7% decrease in

    Matched Cohort Members (CAD) (N=75) Baseline vs. 3 year average = 47.2% increase in co

    Experimental Group (CAD) vs. Matched Cohort (CAD) Members Year by Year

    $-

    $2,000.00

    $4,000.00

    $6,000.00

    $8,000.00

    $10,000.00

    Ornish Members (CAD) Matched Cohort Members

    Ornish Members (CAD) 5377.56 4627.88 5241.27 48

    Matched Cohort Members 5344.32 8586.89 8115.56 68

    baseline year 1 year 2 y

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    Medicare is now covering this p

    for reversing heart diseas

    Medicare is now covering this p

    for reversing heart diseas

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    8 %

    1 %

    -5 %-5 %

    -1 %

    3 %

    7 %

    L o w (< 4 8 % ) M e d iu m

    ( 4 8 - 8 8 % )

    H ig h (> 8 8

    D e g r e e o f L i fe s ty le C h a n g e a nC h a n g e s in P S A

    Ornish D et al. Journal of Urology. 2005;174:1065

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    Change in Prostate Tumor Gr

    (LNCaP)

    -9%

    -70%

    -70%

    -55%

    -40%

    -25%

    -10%

    %FBS

    Co

    Ex

    Ornish D et al. Journal of Urology. 2005;174:1065

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    -7 .9

    -3 8 . 7

    -7 1 . 9

    -8 0

    -6 0

    -4 0

    -2 00

    L o w( < 4 8 % ) M e d i u m( 4 8 - 8 8 % ) H i g h( > 8 8 % )

    D e g r e e o f L i fe s ty le C h a n g e a n d

    In h ib i tio n o f L N C a P T u m o r G r o w

    B a s e lin e -1 2 m c h a n g e in L N C A P c e ll g rOrnish D et al. Journal of Urology. 2005;174:1065

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    1 year latePSA - 4.5 ng

    BaselinePSA - 6.4 ng/ml

    Changes in MRI spectroscopy

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    Change your lifestyle, Changegenes

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    Gene expression in over genes was beneficially

    affected.

    Gene expression in over genes was beneficially

    affected.

    Ornish D et al, Proc Nat Acad Sci 2008; 10

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    Genes controlling tumo

    formation, oxidative stress

    inflammation were

    downregulated.

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    We found a set of RAS fa

    oncogenes

    (RAN, RAB14, RAB8A) todownregulated.

    Downregulation of Oncogenes by Lifestyle Changes

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    Ornish et al. Proc Nat Acad Sci USA 2008; 105: 8369.

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    p <

    Increase in telomerase activity from baseline to 3 month

    Ornish D et al. Lancet Oncol. 2008; 9: 104857.

    Worldwide Life Expectancy GroWorldwide Life Expectancy Gro

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    18201820 19001900 19501950 22

    26Years

    31

    Years

    49Years

    Y

    Source: United Nations Development Program

    +5+5

    +18+18

    +35+35

    Worldwide Life Expectancy GroWorldwide Life Expectancy Gro

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    Lifestyle Affects Quality of LifeU.S. vs. Japan

    Lifestyle Affects Quality of LifeU.S. vs. Japan

    Life ExpectancyLife Expectancy

    67.6 9

    73.6

    Healthy yearsHealthy years

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    U.S. Economy

    $13.84 trillion

    U.S. Economy

    $13.84 trillion

    Lifestyle Makes a DifferencLifestyle Makes a Differenc

    16% = health care spe

    $2.2 tr

    16% = health care spe

    $2.2 tr

    Date: September 22, 2008

    f l k ff

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    U.S. Economy

    $13.84 trillion

    U.S. Economy

    $13.84 trillion

    70% of health-care s

    about $1.5 trillion on lifestyle-related d

    70% of health-care s

    about $1.5 trillion on lifestyle-related d

    Lifestyle Makes a DifferencLifestyle Makes a Differenc

    Date: September 22, 2008

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    Wh t ld t k ?Wh t ld t k ?

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    Who told you to smoke?Who told you to smoke?

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    Wh t ld t k ?Who told you to smoke?

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    Ann SheridanAnn Sheridan BarbaBarbaJoan CrawfordJoan Crawford

    Famous actressesFamous actresses

    Who told you to smoke?Who told you to smoke?

    Who told o to smoke?Who told you to smoke?

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    Your dentist Your dentist

    Who told you to smoke?Who told you to smoke?

    Who told you to smoke?Who told you to smoke?

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    and your doctors and your doctors

    Who told you to smoke?Who told you to smoke?

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    Scientific researchers!Scientific researchers!

    Who told you to smoke?Who told you to smoke?

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    Soldiers and sailorsSoldiers and sailors

    Who told you to smoke?Who told you to smoke?

    Who has NOT been used in cigareWho has NOT been used in cigare

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    Who has NOT

    been used in cigare

    advertisements to get you to smo

    Who has NOT

    been used in cigare

    advertisements to get you to smo

    a.

    Babies

    b.

    Santa Clausc.

    Supreme court justices

    d. U.S. Presidents

    a.

    Babies

    b.

    Santa Clausc.

    Supreme court justices

    d. U.S. Presidents

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    BabiesBabies

    d

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    U.S. PresidentsU.S. Presidents

    lS Cl !!

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    Santa Claus!!Santa Claus!!

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    There is a

    staggeringcost for fail

    to contain t

    containable

    There is a

    staggeringcost for fail

    to contain t

    containable

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    Failure to address chronic disease

    adequately costs the

    U.S. economy more than

    $1 trillion annually.

    Failure to address chronic disease

    adequately costs the

    U.S. economy more than

    $1 trillion annually.

    Chronic Disease StudyChronic Disease Study

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    Diabetes

    Heart disease

    Hypertension Stroke

    Diabetes

    Heart disease

    Hypertension Stroke

    Cancers

    Pulmonary co

    Mental disord

    Cancers

    Pulmonary co

    Mental disord

    Chronic Disease StudyChronic Disease Study

    Obesity Prevalence Among U.S.Obesity Prevalence Among U.S.

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    y g

    1991

    y g

    1991 > 15%> 15%< 15%< 15%

    Obesity Prevalence Among U.S.Obesity Prevalence Among U.S.

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    y g

    2001

    y g

    2001 > > < <

    Obesity Prevalence Among U.S.Obesity Prevalence Among U.S.

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    y g

    2002

    2002 > > < <

    Obesity Rates: U.S. vs. WorObesity Rates: U.S. vs. Wor

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    yy

    20022005

    1.5%1.5%

    1.9%1.9%

    6.6%6.6%

    20.4%20.4%

    24.2%24.2%

    1.8%1.8%

    1.6%1.6%

    7.8%

    20.9%

    21.6%

    36.5%

    JapanJapan

    ChinaChina

    FranceFrance

    GermanyGermany

    U.K.U.K.

    U.S.U.S.MENWOMENWOMEN

    34.3%34.3%24.0%MexicoMexico

    Physical InactivityPhysical Inactivity

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    39% of U.S. childrenages 9-13 take part inorganized exerciseeach week.

    39% of U.S. childrenages 9-13 take part inorganized exerciseeach week.

    29% of U.S.school studentsparticipate in peducation class

    29% of U.S.school studentsparticipate in peducation class

    Physical InactivityPhysical Inactivity

    Treatment Costs Are a Small PortioTreatment Costs Are a Small Portio

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    eat e t Costs e a S all o t o

    Economic Costs

    Economic Costs

    CancerCancer

    $400$400$300$300$200$200$100$100

    HeartHeart

    HypertensionHypertensionMentalMental

    DiabetesDiabetes

    PulmonaryPulmonary

    StrokeStroke

    Direct C

    Indirect

    Source: Milken Institute 2007

    QUIZ:QUIZ:

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    How much larger is the average

    in the U.S. compared to Fran

    How much larger is the average

    in the U.S. compared to Fran1.

    5%2.

    18%3.

    33%4.

    52%5. 74%

    1.

    5%2.

    18%3.

    33%

    4.

    52%5. 74%

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    U.S. soft drink portions are 52% larger

    in France.

    U.S. soft drink portions are 52% larger

    in France.Source: University of Miami School of Medicine/Sheah Rarback, R.D.

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    Candy bars sold in Philadelphia are 4

    larger than those in Paris.

    Candy bars sold in Philadelphia are 4

    larger than those in Paris.Source: University of Miami School of Medicine/Sheah Rarback, R.D.

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    A carton of yogurt in the U.S. is 82% la

    than in France.

    A carton of yogurt in the U.S. is 82% la

    than in France.Source: University of Miami School of Medicine/Sheah Rarback, R.D.

    Fewer carcinogens are detected if you flFewer carcinogens are detected if you fl

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    Source: William Nelson, M.D., Johns Hopkins Hospital

    burgers multiple times.

    burgers multiple times.

    What You Eat MattWhat You Eat Matt

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    15-20% decrease in

    progression of proscancer by increasin

    consumption of fiscooked-tomato protwo servings per w

    after diagnosis.

    15-20% decrease in

    progression of proscancer by increasin

    consumption of fiscooked-tomato protwo servings per w

    after diagnosis.

    What You Eat MattWhat You Eat Matt

    Source: June Chan, ScD, UCSF