gc09_alternativemedicine
Transcript of gc09_alternativemedicine
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DeanOrnish
DeanOrnish
MikeMilken
MikeMilken
WilliamNelson
WilliamNelson
DCDC
Alternative Medicine Joins the MainsAlternative Medicine Joins the Mains
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Consciousness Creates ReaConsciousness Creates ReaCo-create andreflect eachother,interdependentlyco-arise, are atangledhierarchy.
They aresynchronisticallyarising emergentproperties thatco-emerge
depending on thelevel of vibration
of individual andcollectiveconsciousness.
Co-create andreflect eachother,interdependently
co-arise, are atangledhierarchy.
They aresynchronisticallyarising emergentproperties thatco-emergedepending on thelevel of vibration
of individual andcollectiveconsciousness.
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5 Breakthroughs for the 5 Breakthroughs for the
Your body is a process, not a structure.Your body is a process, not a structure.
Your body is an energy field.Your body is an energy field.
Your can turn your genes on and off.Your can turn your genes on and off.
You can change your relationship with timYou can change your relationship with tim
Awareness is the key to transformation aAwareness is the key to transformation a
reinventing the body.reinventing the body.
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Resurrecting the SoulResurrecting the SoulYour life is a flow of effortless spontaneity.Your life is a flow of effortless spontaneity.
Love is the soulLove is the souls only motivations only motivation
You have unlimitedYou have unlimited imaginationimagination and creativityand creativity
You invite Grace in your lifeYou invite Grace in your life
You choose evolution over entropy.You choose evolution over entropy.
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Our health care systemreally a disease care systOur health care systemreally a disease care syst
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$2.1 trillion spent last year
medical care = 16.5% of GD
95% spent to treat disease aft
had already occurred
$2.1 trillion spent last year
medical care = 16.5% of GD
95% spent to treat disease aft
had already occurred
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If we want to make health c
available to the 48 millionAmericans who dont have it,need to address the underly
causes
of disease.
If we want to make health ca
available to the 48 millionAmericans who dont have it,need to address the underly
causes
of disease.
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Cardiovascular diseases kill m
people worldwide each yethan all other illnesses
combined.
Cardiovascular diseases kill m
people worldwide each yeathan all other illnesses
combined.
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In a study of over 30,000 pati
heart disease was completepreventable
for almost 95%
of
just by changing diet and life
Yusuf S et al. Lancet. 2004 Sep 11;364(9438):937-52.
In a study of over 30,000 pati
heart disease was completepreventable
for almost 95%
of
just by changing diet and lifes
Yusuf S et al. Lancet. 2004 Sep 11;364(9438):937-52.
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COURAGE TRIAL
Angioplasty did not reduce
risk of death, heart attackother major cardiovascul
events.
--Boden WE et al. N Engl J Med 2007;356:1-14.
COURAGE TRIAL
Angioplasty did not reduce
risk of death, heart attack,other major cardiovascul
events.
--Boden WE et al. N Engl J Med 2007;356:1-14.
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In 2006, 448,000 coronary byoperations were performed cost of more than $44 billio
In 2006, 448,000 coronary byoperations were performed cost of more than $44 billio
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Coronary bypass surgery prolife in only 2-3% of those w
receive it.
.
--Caracciolo EA et al.Circulation. 1995;91(9):2325-34
Coronary bypass surgery prolife in only 2-3% of those w
receive it..
--Caracciolo
EA et al.Circulation. 1995;91(9):2325-34
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Dangerous, invasive, expenand ineffective
Dangerous, invasive, expenand ineffective
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Coronary heart disease is not
preventable, it is usuallyreversible
by changing dieand lifestyle.
Coronary heart disease is not
preventable, it is usuallyreversible
by changing dieand lifestyle.
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Optimal Lifestyle ProgramOptimal Lifestyle Program
Nutrition
Stress managementModerate exercise
Psychosocial support
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The primary determinant o
improvementwas the degree of lifestyle cha
The primary determinant o
improvementwas the degree of lifestyle cha
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Scaleability
& Cost EffectivenScaleability
& Cost Effectiven
Three demonstration projectsMore than 3,000 patients
Greater changes in diet and lifestyle, larg
improvements in risk factors and quality o
and bigger cost reductions than have ever
been reported in an ambulatory group of
Three demonstration projects
More than 3,000 patients
Greater changes in diet and lifestyle, larg
improvements in risk factors and quality o
and bigger cost reductions than have ever
been reported in an ambulatory group of p
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1. The Multicenter Lifestyl
Demonstration Project
1. The Multicenter Lifestyl
Demonstration Project
Almost 80% of 333 patients who
eligible for bypass surgery or angwere able to safely avoid it.
Ornish D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration PCardiology. 1998;82:72T-76T.
Koertge J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality of life incoronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Card
Almost 80% of 333 patients who w
eligible for bypass surgery or angwere able to safely avoid it.
Ornish D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration PCardiology. 1998;82:72T-76T.
Koertge J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality of life incoronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Card
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2. The Highmark Blue Cross Bl
Shield Demonstration Project:Cost Comparisons After 3 Year
2. The Highmark Blue Cross Bl
Shield Demonstration Project:Cost Comparisons After 3 Year
Experimental Group (CAD) (N=75) Baseline vs. 3 year average = 8.7% decrease in
Matched Cohort Members (CAD) (N=75) Baseline vs. 3 year average = 47.2% increase in co
Experimental Group (CAD) vs. Matched Cohort (CAD) Members Year by Year
$-
$2,000.00
$4,000.00
$6,000.00
$8,000.00
$10,000.00
Ornish Members (CAD) Matched Cohort Members
Ornish Members (CAD) 5377.56 4627.88 5241.27 48
Matched Cohort Members 5344.32 8586.89 8115.56 68
baseline year 1 year 2 y
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Medicare is now covering this p
for reversing heart diseas
Medicare is now covering this p
for reversing heart diseas
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8 %
1 %
-5 %-5 %
-1 %
3 %
7 %
L o w (< 4 8 % ) M e d iu m
( 4 8 - 8 8 % )
H ig h (> 8 8
D e g r e e o f L i fe s ty le C h a n g e a nC h a n g e s in P S A
Ornish D et al. Journal of Urology. 2005;174:1065
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Change in Prostate Tumor Gr
(LNCaP)
-9%
-70%
-70%
-55%
-40%
-25%
-10%
%FBS
Co
Ex
Ornish D et al. Journal of Urology. 2005;174:1065
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-7 .9
-3 8 . 7
-7 1 . 9
-8 0
-6 0
-4 0
-2 00
L o w( < 4 8 % ) M e d i u m( 4 8 - 8 8 % ) H i g h( > 8 8 % )
D e g r e e o f L i fe s ty le C h a n g e a n d
In h ib i tio n o f L N C a P T u m o r G r o w
B a s e lin e -1 2 m c h a n g e in L N C A P c e ll g rOrnish D et al. Journal of Urology. 2005;174:1065
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1 year latePSA - 4.5 ng
BaselinePSA - 6.4 ng/ml
Changes in MRI spectroscopy
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Change your lifestyle, Changegenes
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Gene expression in over genes was beneficially
affected.
Gene expression in over genes was beneficially
affected.
Ornish D et al, Proc Nat Acad Sci 2008; 10
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Genes controlling tumo
formation, oxidative stress
inflammation were
downregulated.
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We found a set of RAS fa
oncogenes
(RAN, RAB14, RAB8A) todownregulated.
Downregulation of Oncogenes by Lifestyle Changes
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Ornish et al. Proc Nat Acad Sci USA 2008; 105: 8369.
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p <
Increase in telomerase activity from baseline to 3 month
Ornish D et al. Lancet Oncol. 2008; 9: 104857.
Worldwide Life Expectancy GroWorldwide Life Expectancy Gro
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18201820 19001900 19501950 22
26Years
31
Years
49Years
Y
Source: United Nations Development Program
+5+5
+18+18
+35+35
Worldwide Life Expectancy GroWorldwide Life Expectancy Gro
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Lifestyle Affects Quality of LifeU.S. vs. Japan
Lifestyle Affects Quality of LifeU.S. vs. Japan
Life ExpectancyLife Expectancy
67.6 9
73.6
Healthy yearsHealthy years
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U.S. Economy
$13.84 trillion
U.S. Economy
$13.84 trillion
Lifestyle Makes a DifferencLifestyle Makes a Differenc
16% = health care spe
$2.2 tr
16% = health care spe
$2.2 tr
Date: September 22, 2008
f l k ff
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U.S. Economy
$13.84 trillion
U.S. Economy
$13.84 trillion
70% of health-care s
about $1.5 trillion on lifestyle-related d
70% of health-care s
about $1.5 trillion on lifestyle-related d
Lifestyle Makes a DifferencLifestyle Makes a Differenc
Date: September 22, 2008
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Wh t ld t k ?Wh t ld t k ?
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Who told you to smoke?Who told you to smoke?
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Wh t ld t k ?Who told you to smoke?
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Ann SheridanAnn Sheridan BarbaBarbaJoan CrawfordJoan Crawford
Famous actressesFamous actresses
Who told you to smoke?Who told you to smoke?
Who told o to smoke?Who told you to smoke?
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Your dentist Your dentist
Who told you to smoke?Who told you to smoke?
Who told you to smoke?Who told you to smoke?
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and your doctors and your doctors
Who told you to smoke?Who told you to smoke?
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Scientific researchers!Scientific researchers!
Who told you to smoke?Who told you to smoke?
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Soldiers and sailorsSoldiers and sailors
Who told you to smoke?Who told you to smoke?
Who has NOT been used in cigareWho has NOT been used in cigare
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Who has NOT
been used in cigare
advertisements to get you to smo
Who has NOT
been used in cigare
advertisements to get you to smo
a.
Babies
b.
Santa Clausc.
Supreme court justices
d. U.S. Presidents
a.
Babies
b.
Santa Clausc.
Supreme court justices
d. U.S. Presidents
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BabiesBabies
d
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U.S. PresidentsU.S. Presidents
lS Cl !!
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Santa Claus!!Santa Claus!!
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There is a
staggeringcost for fail
to contain t
containable
There is a
staggeringcost for fail
to contain t
containable
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Failure to address chronic disease
adequately costs the
U.S. economy more than
$1 trillion annually.
Failure to address chronic disease
adequately costs the
U.S. economy more than
$1 trillion annually.
Chronic Disease StudyChronic Disease Study
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Diabetes
Heart disease
Hypertension Stroke
Diabetes
Heart disease
Hypertension Stroke
Cancers
Pulmonary co
Mental disord
Cancers
Pulmonary co
Mental disord
Chronic Disease StudyChronic Disease Study
Obesity Prevalence Among U.S.Obesity Prevalence Among U.S.
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y g
1991
y g
1991 > 15%> 15%< 15%< 15%
Obesity Prevalence Among U.S.Obesity Prevalence Among U.S.
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y g
2001
y g
2001 > > < <
Obesity Prevalence Among U.S.Obesity Prevalence Among U.S.
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y g
2002
2002 > > < <
Obesity Rates: U.S. vs. WorObesity Rates: U.S. vs. Wor
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yy
20022005
1.5%1.5%
1.9%1.9%
6.6%6.6%
20.4%20.4%
24.2%24.2%
1.8%1.8%
1.6%1.6%
7.8%
20.9%
21.6%
36.5%
JapanJapan
ChinaChina
FranceFrance
GermanyGermany
U.K.U.K.
U.S.U.S.MENWOMENWOMEN
34.3%34.3%24.0%MexicoMexico
Physical InactivityPhysical Inactivity
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39% of U.S. childrenages 9-13 take part inorganized exerciseeach week.
39% of U.S. childrenages 9-13 take part inorganized exerciseeach week.
29% of U.S.school studentsparticipate in peducation class
29% of U.S.school studentsparticipate in peducation class
Physical InactivityPhysical Inactivity
Treatment Costs Are a Small PortioTreatment Costs Are a Small Portio
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eat e t Costs e a S all o t o
Economic Costs
Economic Costs
CancerCancer
$400$400$300$300$200$200$100$100
HeartHeart
HypertensionHypertensionMentalMental
DiabetesDiabetes
PulmonaryPulmonary
StrokeStroke
Direct C
Indirect
Source: Milken Institute 2007
QUIZ:QUIZ:
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How much larger is the average
in the U.S. compared to Fran
How much larger is the average
in the U.S. compared to Fran1.
5%2.
18%3.
33%4.
52%5. 74%
1.
5%2.
18%3.
33%
4.
52%5. 74%
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U.S. soft drink portions are 52% larger
in France.
U.S. soft drink portions are 52% larger
in France.Source: University of Miami School of Medicine/Sheah Rarback, R.D.
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Candy bars sold in Philadelphia are 4
larger than those in Paris.
Candy bars sold in Philadelphia are 4
larger than those in Paris.Source: University of Miami School of Medicine/Sheah Rarback, R.D.
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A carton of yogurt in the U.S. is 82% la
than in France.
A carton of yogurt in the U.S. is 82% la
than in France.Source: University of Miami School of Medicine/Sheah Rarback, R.D.
Fewer carcinogens are detected if you flFewer carcinogens are detected if you fl
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Source: William Nelson, M.D., Johns Hopkins Hospital
burgers multiple times.
burgers multiple times.
What You Eat MattWhat You Eat Matt
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15-20% decrease in
progression of proscancer by increasin
consumption of fiscooked-tomato protwo servings per w
after diagnosis.
15-20% decrease in
progression of proscancer by increasin
consumption of fiscooked-tomato protwo servings per w
after diagnosis.
What You Eat MattWhat You Eat Matt
Source: June Chan, ScD, UCSF