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G H U L A M A B B A S HEC APPROVED SUPERVISOR OF PHARMACOLOGY

PERSONAL INFORMATION

Date of Birth February 20, 1982

Gender Male

CNIC No. 42501-5189908-5

Passport No. HG1019081

Religion Islam

Marital Status Married

Mobile +92 333 34 76 182

E-mail ghulam.abbas@hotmail.com

Work Address Lab-313, H.E.J. Research Institute of Chemistry

ICCBS, University of Karachi

Karachi-75270, Pakistan

Tel: (92-21) 99261737 or 111-222-292 Ext: 137

ghulam.abbas@iccs.edu

Home Address B-88, Shah Faisal Town, Jinnah Avenue,

Karachi-75100, Pakistan

Tel: (92-21) 34590269

EDUCATION

M.Phil. / Ph.D. in Pharmacology

[2012] [CGPR: 3.77] [Supervisor: Prof. Dr. Ahsana Dar Farooq]

[Title: Behavioral, biochemical and immunohistochemical

effects of Areca catechu on depressive models of rodents]

[Pharmacology Section, H.E.J. Research Institute of Chemistry,

International Center for Chemical and Biological Sciences,

University of Karachi, Karachi, Pakistan]

Bachelor of Pharmacy

[2001-2004] [CGPR: 3.41] [University of Karachi, Pakistan]

Intermediate (Pre-Medical)

[1997-2000] [Grade A] [D.J. Sindh Govt. Science College,

Karachi, Pakistan]

Matriculation

[1995-1997] [Grade A-1] [C.A.A Model School No. 1 (K.B.V),

Karachi, Pakistan]

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WORK EXPERIENCE

Assistant Professor (Tenure Track System)

H.E.J. Research Institute of Chemistry

International Center for Chemical & Biological Sciences (ICCBS)

University of Karachi

Sep. 2015 – Onwards

Description:

Supervising research students in the field of pharmacology.

In-charge Patch clamp facility

Assistant Professor (Tenure Track System)

Department of Pharmacy

COMSATS Institute of Information Technology (Abbottabad)

Aug. 2012 – Aug. 2015

Description:

Teaching Pharm.D., MS and Ph.D. students of pharmacy.

Supervising research students in the field of pharmacology.

Member of Center for Advance Drug Research (CADR).

In-charge animal house facility.

Executive R&D / Head Pharmacology Section

Herbion Pakistan Pvt. Ltd.

Dec. 2010 – Aug. 2012

Description:

Conduct / facilitate pharmacological studies of phyto

pharmaceuticals as per regulatory requirements.

Development of animal house facility.

Research Fellow

Pharmacology Section, H.E.J. Research Institute of Chemistry,

ICCBS, University of Karachi, Karachi, Pakistan.

Jan. 2006 – Aug. 2012

Description:

Conducting research as part of my M.Phil. / Ph.D. work

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Quality Control Analyst

Glaxosmithkline Pakistan Ltd.

Feb. – Sep. 2005

Description:

Ensure the quality of Augmentin, Amoxil, Ampiclox, Macleans

and ENO using equipments such as HPLC, FT-NIR, Karl Fisher,

U.V, Disintegration & Dissolution assemblies

RESEARCH SUPERVISION

S. No. Name Title Degree Year

1 Wahid Zada

Anti-depressant Evaluation of the

Methanolic Extracts of Traditionally

Used Plants Using Behavioral Paradigms

in Rodents

MS 2014

2 Sara Zeeshan

Preclinical Evaluation of the Methanolic

Extracts of Traditionally Used Plants for

Antidepressant Activity Using

Behavioral Assays

MS 2014

3 Ali Haider Evaluating Cholinergic Modulator in

Scopolamine Induced Cognitive

Impairment in Rodents

MS 2015

4 Shahab Ali

Khan

Preclinical Evaluation of the Selected

Glycation Modulator Against Cognitive

Impairment

MS 2015

5 Saniya

Hashim

Evaluating Glucocorticoid Modulator in

Stress Associated Memory Impairment

in Rodents.

MS 2015

RESEARCH CO-SUPERVISION

06 MS students (Completed)

03 PhD students (under progress)

RESEARCH INTERESTS

Pharmacology of Stress, learning & memory

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RESEARCH GRANTS AWARDED

S. No. Title Amount

(Million)

Funding

Source Year

1

Preclinical evaluation of natural

substances for antidepressant potential

using behavioral assays.

0.5 HEC 2013

2

Evaluating nootropic claim of herbal

products using behavioral paradigms:

Targeting amyloid and cholinergic

hypotheses of Alzheimer’s disease

0.15 CIIT 2015

BOOK CHAPTER

Chapter 73 - General Aspects of Areca Nut Addiction

Book: Neuropathology of Drug Addiction & Substance Misuse

Editor: Victor R. Preedy (Kings College London, London, UK)

Publisher: Elsevier, 2016 (Vol. 3)

ISBN: 978-0-12-800634-4

AWARDS & HONORS

Research Productivity Award 2015 (COMSATS)

Editorial Board Member (Hamdard Medicus)

REVIEWER

Acta Pharmacologica Sinica (Journal – Nature Publishing Group)

Journal of Ethnopharmacology (Journal - Elsevier)

Molecular Therapy (Journal – Nature Publishing Group)

Natural Product Research (Journal – Taylor & Francis)

Pharmacology Biochemistry & Behavior (Journal – Elsevier)

Pharmaceutical Biology (Journal – Informa Health Care)

Phytotherapy Research (Journal – Wiley)

CONFERENCES / WORKSHOPS

2017: 4th International Conference on Unani Medicine, Hamdard

University, Karachi, Pakistan

2016: 14th Euroasia conference on Chemical Sciences, ICCBS,

Karachi, Pakistan

2015: 4th Pak-France Bi-national Workshop on Drug Development

and Molecular Medicine, Karachi, Pakistan

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2015: Intellectual Property Rights and Entrepreneurship in

Pakistan, ICCBS, Karachi, Pakistan

2015: Drug development – Natural & Synthetic, COMSATS

Institute of Information Technology, Abbottabad, Pakistan

2013: Drug development – Natural & Synthetic, COMSATS

Institute of Information Technology, Abbottabad, Pakistan

2013: Faculty Development Workshop, COMSATS Institute of

Information Technology, Abbottabad, Pakistan

2010: 12th International Symposium on Natural Product Chemistry

(ISNPC), Karachi, Pakistan

2009: 2nd International Symposium and Workshop-cum-Training

Course on Molecular Medicine and Drug Research (MMDR),

Karachi, Pakistan

2008: 11th (ISNPC), Karachi, Pakistan.

2007: 1st IBRO Associate School of Neuroscience, Karachi,

Pakistan.

2007: 1st Nation-wide Patch Clamp Workshop, Karachi, Pakistan

ORAL PRESENTATIONS

1. “Natural Neuro-modulators: Examples from our Research & Future Prospect” at

4th International Conference on Unani Medicine, Hamdard University, Karachi,

Pakistan (Jan 10, 2017)

2. Invited lecture entitled “The challenges in research for beginners” at 2nd Annual

Research Day, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana,

Pakistan (April 21, 2016)

3. Invited lecture entitled “Depression & its Treatment: Past, Present & Future” at

Academic Research Session, Dow University of Health Sciences, Karachi,

Pakistan (April 18, 2016)

4. “β – glucan attenuated scopolamine induced impairment in learning & memory

via hippocampal acetylcholinesterase inhibition in rats” at 4th Pak-France Bi-

national Workshop on Drug Development and Molecular Medicine, ICCBS,

University of Karachi, Karachi, Pakistan (Oct 14, 2015)

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5. “β – glucan ameliorated scopolamine induced cognitive impairment via

acetylcholinesterase inhibition in the hippocampus of rats” at workshop on Drug

development: Natural & Synthetic, Centre for Advanced Drug Research,

COMSATS Institute of Information Technology, Abbottabad, KPK, Pakistan

(Aug, 2015)

PUBLICATIONS (CITATIONS = 47; H-INDEX = 4; I10-INDEX = 1)

Shahab Ali Khan, Ali Haider, Wajahat Mahmood, Talat Roome and Ghulam Abbas*.

Gamma linolenic acid ameliorated glycation induced memory impairment in rats.

Pharmaceutical Biology 2017 (Accepted)

Neelam Zaman, Hammad Ahmad, Mobasher Ali Abid, Nisar-ur-Rahman, Talat Roome and

Ghulam Abbas*. Acetaminophen (Paracetamol) facilitated extinction learning in contextual

fear conditioned rats. Letters in Drug Design & Discovery 2017;

DOI: 10.2174/1570180814666170203162557

Mobasher Ali Abid, Muhammad Ashfaq, Muhammad Junaid Hassan Sharif, Khalid Rauf,

Wajahat Mahmood, Ikarmullah Khan and Ghulam Abbas*. Total antioxidant capacity of

commonly used fruits, vegetables, herbs and spices of Pakistan. Pakistan Journal of

Pharmaceutical Sciences 2017 (Accepted)

Ali Haider, Wali Inam, Shahab Ali Khan, Hifza, Wajahat Mahmood and Ghulam Abbas*. β

– glucan attenuated scopolamine induced cognitive impairment via hippocampal

acetylcholinesterase inhibition in rats. Brain Research 2016; 1644: 141-148

Sara Zeeshan, Wahid Zada, Huma Aslam Bhatti, Ghulam Abbas*. Cuscuta reflexa: an

implication of quercetin mediated monoamine oxidase inhibition in preclinical models of

depression. Hamdard Medicus 2016; 59(1): 17-23.

Mohamad Khairul Azali Sahak, Nurul Kabir, Ghulam Abbas, Suhaimi Draman, and

Durriyyah Sharifah Hasan Adli. The role of Nigella sativa and its active constituents in

learning and memory. Evidence Based Complementary and Alternative Medicine 2016

(Article ID 6075679).

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Ghulam Abbas*, Wajahat Mahmood and Nurul Kabir. Recent progress on the role of

GABAergic neurotransmission in the pathogenesis of Alzheimer’s disease. Reviews in the

Neurosciences 2016; 27(4): 449-455

Wahid Zada, Sara Zeeshan, Huma Aslam Bhatti, Wajahat Mahmood, Khalid Rauf and

Ghulam Abbas*. Cinnamomum cassia: an implication of serotonin reuptake inhibition in

animal models of depression. Natural Product Research 2016; 30(10): 1212-1214

Muhammad Sona Khan, Aneela Gohar, Ghulam Abbas, Wajahat Mahmood, Khalid Rauf

and Robert D. E. Sewell. Thymoquinone inhibition of acquisition and expression of alcohol-

induced behavioral sensitization. Phytotherapy Research 2015; 29: 1610-1615.

Sohail Mohammad, Usman Arshad, Nasir Abbass, Irfan Parvez, Ghulam Abbas, Wajahat

Mahmood. Bioequivalence Study of Atorvastatin Tablets in Healthy Pakistani Volunteers.

Therapie 2015; 70: 329-335

Ghulam Abbas*, Khalid Rauf, Wajahat Mahmood. Saponins: The phytochemical with an

emerging potential for curing clinical depression. Natural Product Research 2015; 29: 302-

307

Usman Arshad, Mobasher Ali Abid, Muhammad Ashfaq, Muhammad Junaid Hassan Sharif,

Ghulam Abbas, Wajahat Mahmood, Robert D. E. Sewell and Khalid Rauf. Is there a

negative correlation between a phenelzine sub-acutely induced antidepressant-like behaviour

and hippocampal 5-HT? Pharmacology Online 2014; 2: 54-60

Gowhar Ali, Fazal Subhan, Nazar Ul Islam, Nasir Ullah, Muhammad Shahid, Samiullah,

Ihsanullah, Rehmat Shah, Ikhtiar Khan, Robert D. E. Sewell and Ghulam Abbas.

Comparative evaluation of gastroulcerogenic potential of nitrogen isoforms of salicyl alcohol

and aspirin in rats: biochemical and histological study. Archives of Pharmacal Research 2014;

37: 916-926

Khalid Rauf, Fazal Subhan, Muzaffar Abbas, Syed Mobasher Ali, Gowhar Ali, Muhammad

Ashfaq and Ghulam Abbas*. Inhibitory effect of Bacopasides on spontaneous morphine

withdrawal induced depression in mice. Phytotherapy Research 2014; 28: 937-939

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Shagufta Khan, Ghulam Abbas, Fahad Shabbir Ahmed, Atta-ur-Rahman and Ahsana Dar.

Effect of dichloromethane fraction of areca catechu nut on monoamines associated behaviors

and tyramine pressor sensitivity in rats. Pakistan Journal of Pharmaceutical Sciences 2014;

27: 303-307

Ghulam Abbas, Sabira Naqvi, Shaista Erum, Shakil Ahmed, Atta-ur-Rahman and Ahsana

Dar. Potential antidepressant activity of Areca catechu nut via elevation of serotonin and

noradrenaline in the hippocampus of rats. Phytotherapy Research 2013; 27: 39-45

Khalid Rauf, Fazal Subhan, Ghulam Abbas, Gowhar Ali, Syed Mobasher Ali Abid, Usman

Arshad and Muhammad Junaid Hassan Sharif. Bacopa monnieri inhibits locomotor

hyperactivity induced by morphine without altering noradrenaline. Pharmacology Online

2013; 1: 172-181

Ghulam Abbas, Sabira Naqvi and Ahsana Dar. Comparison of monoamine reuptake

inhibitors for immobility time and serotonin levels in the hippocampus and plasma of sub-

chronically forced swim stressed rats. Pakistan Journal of Pharmaceutical Sciences 2012; 25:

441-445

Ghulam Abbas, Sabira Naqvi, Shahab Mehmood, Nurul Kabir and Ahsana Dar. Forced

swim stress does not affect monoamine levels and neurodegeneration in rats. Neuroscience

Bulletin 2011; 27: 319-324