Future of Biotech, Innovation in Healthcare - Conference Keynote Speaker
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Transcript of Future of Biotech, Innovation in Healthcare - Conference Keynote Speaker
Dr Patrick Dixon Chairman Global Change LtdFellow, Centre for Management Development, London Business School
What Future for Biotech ?
Patrick Dixon is Chairman of Global Change Ltd, Author of 15 books and has been ranked one of the 20 most influential business thinkers alive today (Thinkers 50)
Future of Biotech, Innovation in Healthcare for Novo Nordisk (2012)
500 videos of keynoteswww.youtube.com/pjvdixon
over 4 million views
www.globalchange.com14 million unique visitors
Wild Cards: Risk Management
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Web - SMS
Global Brand Growth
Indonesia: Islamic radicalisation88% of 200 million
Expect struggle for political power by radical groups in Indonesia, Malaysia
1 billion children cities
Demographics - Future World and future Novo Nordisk
Middle Class --> food --> diabetes: 300m India - 100m Africa
18 million children in Turkey will be adults in next 15 years
Europe Dying
4 couples needed to produce just one
great-grandchild
75% of all US and UK wealth owned by those over 65
1 million voters over 90 years old in Italy by 2026
Growing global gap - rich and poor 100 own equivalent 25% of GDP in India
Future Health = emotion
Future in developed markets is about performance not wellness
“Yesterday’s drugs were about need: tomorrow’s will be about living faster and staying young”
People Want to Look Better•51% growth in botox treatment•31% growth laser hair removal•31% growth in cosmetic surgery enquiries•(UK 2007 2008)
Sexual Performance
Brain Faster – and better?
may be
Remote diagnostics and image reporting Your own personal tech may be better than in hospital
Genetic Prophecy – Are We Ready?
Read Human Genome in an Hour•Fluidics•Biochemistry•Genetics•Mathematics•Immunology•Robotics
Genes for speech, memory, criminality, depression, obesity and stable relationships
Innovation in Ageing
Permanent Hair Colour•Adenovirus • Infected mouse hair cells•Permanent colour change
Worn out Mitochondria – Energy Boost
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KB-141 Thyroxine Analogue Boosts Metabolism
•$100 billion / year cost to US economy of OBESITY / DIABETES•1 in 3 babies born in New York --> Type 2 Diabetes
•Synthetic form of thryroxine increases metabolic rate•Obese monkeys lost up to 7% of body mass in 7 days•Heart rates were unchanged•Karo Bio made KB-141 - tested by Bristol-Myers Squib
Treatment which restores and maintains the youthful elasticity of hardened arteries – and
helps wrinkled skin. Global sales?
Caloric Restricted Mice Live LongerStephen Spindler Biomarker Pharmaceuticals
These animals also develop fewer cancers – but prone to infection / other problems
Monkeys on diet live longer•After 20 years - 80% alive v 50% on normal calories•Less cancer, diabetes, heart disease, strokes, brain decay
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•Age-onset diabetes Rx for many years •Extends lifespan of non-diabetic mice by 20% if started in late middle age
•Few side effects or toxicity when given to non-diabetic humans
•Rapid growth in self-medicated people hoping to extend healthy living
•Cost 20 cents a day•70% of age-related gene changes in mice are reversed in 2-4 weeks with caloric restriction
•Similar changes are found when using metformin
Near-perfect repair of heart or brain damage following
coronary / strokeusing adult stem cells
Your Brain Can Repair
ItselfDaily
We can transform cells in a laboratory – but far better would be to transform them where they
are in the body, using pharma products
Diabetes – New Approaches•Direct transformation of liver to healthy pancreatic cells using simple injections every three months…
•Achieved in tadpoles and in human liver culture
Slow or no ageing is a reality
•Rockfish, Turtles, some Whales
•No signs of getting old
Impact on Budgets and Health Rations
Making a Difference - a Better World
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•Share your vision
•Show people why it really matters
•Show people how we will get there
•Give each person an important part to play
•Celebrate each success along the way
Creating a Better FutureLiving the strategy in your own team
Dr Patrick Dixon Chairman Global Change Ltd
Slides and Videos: globalchange.com
14 million visitors - 4 million videos
Patrick Dixon is Chairman of Global Change Ltd, Author of 15 books and has been ranked one of the 20 most influential business thinkers alive today (Thinkers 50)
Future of Biotech, Innovation in Healthcare for Novo Nordisk (2012)
500 videos of keynoteswww.youtube.com/pjvdixon
over 4 million views
www.globalchange.com14 million unique visitors