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9th PAN-ARAB HEMATOLOGY & 18th SAUDI SOCIETY OF HEMATOLOGY CONGRESS

Toward improving survival & quality of life for hematological disorders Hormuz Grand Muscat, A Radisson Collection Hotel

27- 29 February 2020, Muscat- Oman Thursday 27th February 2020 17:00-17:30 Registration

17:30-19.30 Parallel Workshops 1. Transfusion workshop for technologists Organizer: Arwa Al- Riyami 2. Nursing Workshop, Organizer: Iman Dawiyani 3. Flowcytometry Workshop, Organizer: Athraa Al-Mawali, Speaker: Marie Bene, France

Friday 28th February 2020 8.00-8:45 Registration

8:45-9.15 Opening Ceremony Dr. Abdulhakim Al-Rawas, President of Omani Society of Hematology ,Prof. Soad Al Jaouni President of Saudi Society of Hematolog , KSA, & Prof. Mohamed Qari, President of Pan-Arab Hematology

Chairperson Prof. Mohamed Qari & Dr. Muhana Al-Muslehi Session 1 9:15-10:15

Keynote Lectures Speaker : Shaker A. Mousa, PhD, MBA, FACC, FACB,USA 1-Impact of Nanobiotechnology on the Future of Medicine: The Road from Nanomedicine to Precision Medicine emphasis on Hematological diseases

2-Antithrombotic Efficacy without any systemic Anticoagulation

Chairperson Prof. Soad Al Jaouni & Prof. Miguel Aboud

Session 2 10.15-12.15

Plenary Session: Sickle Cell Disease 1. Transition care in SCD, Salam al Kindi, Oman 2.Together we will stop sickle cell cycle” A unique and a successful story by the sickle cell community care in Maternity Hospital, Najat Rouh Al-Deen, Kuwait 3.Therapeutic advances and Optimization of Hydroxyurea use in SCD, Hatoon Ezzat, KSA 4. Gene therapy in SCD: Where we are?, Miguel Aboud, Lebanon

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12:15-13.00 Friday Prayers and Lunch Group Photo 12:15

Chairperson Prof. Mohsen Elalfy & Prof. Amal Elbeshlawy

Session 3 13.00-13.30

Industrial symposia-I (2 in parallel) Thalassemia/ Blood components 1-Speaker : Eissa Agour, PhD - Medis Medical Imaging System and ESNA Healthcare, Netherlands Update on iron overload assessment with MRI T2* 2-Speaker: Octapharma Co. Blood Components

Chairperson Prof. Salwa Hindawi & Dr. Arwa Al Riyami

Session 4 13.:30-15:00

Plenary Session Session 4: Transfusion Medicine (4 speakers, 20 minutes each+ 10 min discussion) 1. The challenge of screening blood donors for malaria, UAE experience, May Raouf, UAE 2. Genotyping as a milestone in blood transfusion support, Reem Redwan, Kuwait 3. Blood banking in clinical practice, Salwa Al Hindawi, KSA 4. TACO, TRALI and beyond, Arwa Al Riyami, Oman

15:00-15:30 Coffee break

Chairperson Dr. Murtadha Alkhabori & Dr. Mohammad Al Shahrani Dr. Abdulhakim Al-Rawas & Dr. Naima Al Mullah Session 5 15:30-17:00

Session: (Oncology) Leukemia/ Lymphoma and Bone Marrow Transplantation (5 speakers, 15 minutes each+ 10 min discussion) 1. Mixed phenotype of acute leukemia's differentiates from

normal diagnosis guidelines, Marie Bene, France

2. Novel thyrointegrin avB3 antagonist for the treatment of acute myeloid leukemia, Shaker A. Mousa, USA

3. Updates on non-Hodgkin’s lymphoma, Khalil Al Farsi, Oman

4. Bone marrow transplant: an update, Asma Sultan Al Ulama, UAE

5. Use of maintenance therapy post-BMT to decrease disease relapse, Murtadha AlKhabori, Oman

Parallel Session: (Hematology): Rare blood disorders, quality and transfusion update: (5 speakers, 15 minutes each+ 10 min discussion) 1. Molecular genetics of Bernard Soulier Syndrome (BSS), Nouf

Alnumair, KSA 2. Paroxysmal nocturnal hemoglobinuria, Hanan Hamed, Egypt 3. Gaucher’s Disease, Amal Elbeshlawy, Egypt 4. Association of Familial Hodgkin Lymphoma with Deficiency of

Adenosine Deaminase 2 (DADA2), Ghaleb Elyamany, KSA 5. Issues related to antiphospholipid management, Bader Al Rawahi ,

Oman

19:00-22:00 GALA Dinner, Distribution of Awards Rozna Restaurant (Castle), Muscat

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Saturday 29th February 2020 Chairperson Prof. Layla Bashawri & Dr. Najat Ali Roohaldeen Prof. Salam Al Kindi & Dr. Karima Al Hinaii

Session 1 8:00-10:00

Session: (Hematology) Thrombosis & Hemostasis-I (5 speakers, 15 minutes each+ 10 min discussion) 1. Evidence based management of pediatric thrombophilia,

Azzah Tantawi, Egypt 2. Molecular genetics of a rare inherited bleeding disorder,

Nouf Alnumair, KSA 3. Bleeding in a girl, what is behind it? Galila Mokhtar, Egypt 4. Highlights on diagnostic algorithm of DIC and sepsis induced coagulopathy , Galila Zaher, KSA 5.Reducing risk of DVT in pregnancy, Najat Ali Roohaldeen, Kuwait

Parallel Session: (Hematology): Thalassemia & Iron metabolism (5 speakers, 15 minutes each+ 10 min discussion) 1. Management of Endocrinopathies in thalassemia, recent advances, Mohsen Elalfy, Egypt 2.Effect of genetic insult on presentation of thalassemia, Azza Mustafa, Kuwait 3. Thalassemia in the new Era towards better survival and Quality of life, Amal El Beshlawy, Egypt 4. Case studies in thalassemia, Yasser Wali, Oman 5. Genetic manipulation of iron metabolism, Hanan Hamed, Egypt

9.00-10.30 Coffee Break

Chairperson Prof. Abdulkareem Al Momen & Dr. Ibrahim AlGhaithi Prof. Mervat Mattar & Dr. Hatem Alahwal

Session 2 10.30-12:00

Session: (Hematology) Thrombosis & Hemostasis-II speakers, 15 minutes each+ 10 min discussion)

1. Sheep mucosal heparin and enoxaparin are biosimilar to porcine mucosal heparin and enoxaparin, Yiming Yao, China

2. Routine preoperative coagulation tests: are they necessary? Azza Zahrani, KSA

3. Updates of DOAC management in Venous thrombosis, Ali Al Mohaymani, Kuwait

4. Improving quality of care of Hemophilia in Saudi Arabia: real life challenges, Essam Alghamdi, KSA

5. Impact of iron deficiency anemia on the function of the immune system in children, Marwa Zakaria, Egypt.

Session: (Oncology) Leukemia & MPN (5 speakers, 15 minutes each+ 10 min discussion) 1. History of Leukemia Management in Oman, Zakia Al Lamki, Oman 2. Integrated diagnosis of acute leukemia , MC Bene, France 3. Myeloproliferative Neoplasms in the Arab World,

Mervat Mattar, Egypt. 4. Eosinophilia and mastocytosis: Another shade of MPN,

Hanan Hamed, Egypt. 5. Diagnostic challenges in MDS: Is there a role of Flow Cytometry?

Azza Kamel , Egypt

Session 3 12:00-13.30

Lunch break Including 2 Parallel Industrial symposia- Chairman Prof. Yasser Wali

1. Hemophilia Roche

Updates on management of Hemophilia, Hazza Alzahrani, Saudi Arabia 2.SCD

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Chairperson Dr. Ahmed Barefah & Dr. Sulayma Al-lamki Dr. Mona Al-Riyami & Dr. Azza Al Zahrani

Session 4 13:30-15:00

Plenary Session: (Hematology) Hematological disorders and Bone marrow failure (5 speakers, 15 minutes each+ 10 min discussion)

1. Extracorporeal photo-pheresis, application update, Hind Humaidan, KSA

2. Minimal residual disease Evolution of technology and

clinical impact, Azza M Kamel, Egypt 3. Bone Marrow failure congenital and acquired, Syed Osman,

KSA 4. Next generation sequencing in the diagnosis of

hematological disorders, Samah Nabeel Saharti, KSA 5. Impact of sickle cell disease (SCD) symptoms on patients

daily lives and management strategies in the middle east : results from the international sickle cell world assessment survey (SWAY), Michelle Wallwin, UK

Oral abstract presentations Parallel session (10 minutes)

1. Effect of hydroxyurea use on development of AVN among young Omani sickle cell disease patients, Iman Al Fadhli, Ped. resident, Oman

2. Clinical and MRI decision making rules in differentiating VOCs from osteomyelitis in Pediatric Sickle Cell population. Ahmed Al Shukaili, Ped. Resident, Oman

3. Impact of Mutations in Epigenetic Modifiers in Acute Myeloid Leukemia: a Systematic Review and Meta-analysis, Fatma Al-Bulushi, Oman

4. Alterations of gut microbiome in Untreated Chronic Lymphocytic Leukemia (CLL); Future Therapeutic Potentials. Mohammed Kawari , KSA

5. Soluble Carcinoembryonic Antigen Cell Adhesion Molecules

1, 6 and 8 in Acute Myeloid Leukemia: their relation to

survival and prognosis, Dr Nahla A. Abd Alltif, KSA

6. Expression of tolerogenic HLA-G & immunoglobulin-like transcript (CD85) confer worse outcome in CLL, Magda Assem, Egypt

7. Impact of Mutations in Epigenetic Modifiers in Acute Myeloid Leukemia : a Systematic Review and Meta-analysis, Fatma Albulushi, Oman

8. The Clinicopathological impact of Granulocyte-Macrophage

Colony-Stimulating Factor gene expression and different

molecular prognostic biomarkers in Egyptian acute myeloid

leukemia patients , Neemat Kassem, Egypt

15:00-15:30 Coffee break

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Chairperson Dr. Salem Bahashwan & Dr. Mohamed Al-Hinaii Dr. Ibrahim Khidir Ibrahim & Dr. Khalil Al-Farsi

Session 5 15.30—16:30

Oral abstract presentations Parallel session (10 minutes) 9. Spectrum clinical characteristics and outcomes of VWD in

Oman, Shamsa Al Kaabi, Ped. resident, Oman 10. Stable Mixed Chimerism after hematopoietic stem cell

transplantation in patients with sickle cell disease, Musleh AL Muselhi, Oman

11. Impact of iron deficiency anemia on the function of the immune system in children, Marwa Zakaria, Egypt

12. Clinical and Magnetic Resonance Imaging (MRI) Decision Making Rules in Differentiating Vaso-Occlusive Crises (VOCs) from Osteomyelitis in Paediatric Sickle Cell Population: Is MRI Pathognomonic? Ahmed Al Shukaili , Oman

Oral abstract presentations Parallel session (10 minutes) 13. Mutation analysis of CALR gene using conformational

sensitive gel electrophoresis (CSGE) in BCR-ABL negative myeloproliferative neoplasm patients, Ibrahim Khidir Ibrahim, Sudan

14. Early pre-microscopic differentiation of Acute Promyelocytic

Leukemia: the convergence of Cell Population Data and

Artificial Intelligence, Rana Haider, Pakistan

15. The impact of the new policy of deferring HBV core anti- body reactive donors on blood stock, single center experience in

Saudi Arabia, Mohammad Al Mohammadi, KSA

16. Spectrum Clinical Characteristics and Outcome of von Willebrand disease in Oman , Shamsa Alkaabi, Oman

16:30 Closing remarks Dr. Abdulhakim Al-Rawas, President of Omani Society of Hematology Group Photo

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Friday& Saturday 8:00 – 16:00

Poster Session

Chairperson Dr. Salwa Al Najjar & Dr. Nawal Al-Meshaikhi 1 Honey is a Good Nutrition and Improves the Quality of Life Outcomes and Decreased the Painful Crisis in Sickle Cell

Disease, Shahd Naghi, KSA 2 Primary Gastric Lymphoma Types and Pathological Pattern : A Tertiary Hospital Experience, Saeed Alshieban , King

Abdulaziz Medical City, Riyadh 3 Double Hematological and solid Malignancy Diagnosed from Bone Marrow Studies : Case Report, Laboratory View,

Manar Ismail, KSA 4 Pre-Transfusion Antibodies testing : Experience of a blood bank at Madinah Saudi Arabia, Dr. Maher AlJohani, KSA 5 Deferral for malaria risk : An increasing concern on blood availability in Oman , Khalid Alhabshi, Oman 6 Evaluation of reflex high- performance liquid chromatography as screening modality for hemoglobinopathy in sultan

Qaboos University Hospital : A Quality Project , Ammar Al Sheriyani, Oman 7 Correlation between one-stage clot-based and chromogenic factor VIII activity assay results,

Radhiya Al Buraidi, Oman 8 Preoperative transfusion in pediatric patient with sickle cell disease, Mohamed Al Darwish, KSA 9 Quality indicator in a hematology laboratory: performance of the notification system of critical results,

Maher Al Johani , KSA 10 Prognostic significance of interleukin 27 serum level in children with immune thrombocytopenia,

Dr. Tamer Hassan, Egypt 11 Leukemia diagnosis in Yemen, Saleh Abuhadi. Yemen