Free Classroom Resources from HHMI for Teaching Evolution, Part 2 Megan Stine [email protected] June...
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Transcript of Free Classroom Resources from HHMI for Teaching Evolution, Part 2 Megan Stine [email protected] June...
- Slide 1
- Free Classroom Resources from HHMI for Teaching Evolution, Part 2 Megan Stine [email protected] June 19, 2014
- Slide 2
- Evolution: Behind the Scenes
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- Evolving Switches, Evolving Bodies Film guides Virtual lab Classroom activities: Using Genetic Crosses to Analyze a Stickleback Trait Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish
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- Evolving Switches, Evolving Bodies Film http://www.hhmi.org/biointeractive/making- fittest-evolving-switches-evolving-bodies http://www.hhmi.org/biointeractive/making- fittest-evolving-switches-evolving-bodies
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- Which phenotype is dominant? Assumption: single-gene trait, 2 alleles, normal dominance Cross between a marine stickleback and one from Bear Paw Lake Parents are homozygous F is dominant, f is recessive
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- Predict the results of the crosses FF f f Ff Pelvic spines present:absent = 0:1 1:0 Ff F f FF Ff ff Pelvic spines present:absent = 3:11:3 1 st generation2 nd generation
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- Sorting by Phenotype With pelvic spinesWithout pelvic spines
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- Do the data support your hypothesis? Sort the F 1 cards: Fish with pelvic spines Fish without pelvic spines Sort the F 2 cards Ratio of fish with:without pelvic spines in F 1 ? Ratio of fish with:without pelvic spines in F 2 ? 1:0 3.4:1 Was our initial assumption correct? Is this a single-gene trait? Was your hypothesis correct? Which phenotype is dominant?
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- Virtual Lab
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- Natural Selection in Humans Film guides Classroom resources: Nature of Science Mendelian Genetics, Pedigrees, and Chi- square Analysis How Fibers Form Population Genetics
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- Natural Selection in Humans Film http://www.hhmi.org/biointeractive/making- fittest-natural-selection-humans http://www.hhmi.org/biointeractive/making- fittest-natural-selection-humans
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- Mendelian Genetics Activity Punnett squares Pedigree analysis Pedigree creation Chi-square analysis Data prediction Important notes: A is normal allele S is sickle cell allele AA has normal RBC phenotype AS has sickle cell trait SS has sickle cell disease
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- Question #1: Intro Punnett AS A S Chance of normal RBC in high and low oxygen? Chance of SCD? Chance of 3 children with SCD? Chance of 2 children with sickle cell trait and 1 with SCD? Child without SCD, what chance he/she has trait? AA AS SS 1/4 1/64 1/16 2/3
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- Question #6: Intro Pedigree Genotype of: 1 st gen male? 2 nd gen daughter? Individual #3? If family moves to lowlands of E. Africa, 4/5 males will have two genetic advantages. What are they? AS SS AS
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- Human Evolution Click & Learn
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- Teacher Guides
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- Holiday Lecture Series
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- BioInteractive.org
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- Coming in Fall 2014
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- Thank you for your time and attention! [email protected] Sign up for our newsletter at biointeractive.org Like us on Facebook!