Food as Medicinebb4751b3-726b-4eaf... · After 2 years: 65-75% of the participants are stil...
Transcript of Food as Medicinebb4751b3-726b-4eaf... · After 2 years: 65-75% of the participants are stil...
Food as Medicine:How to reverse Type 2 Diabetes through diet change
Dr. Peter J VosholIntegrative Physiologist
Senior Scientist Nutrition and Health Louis Bolk Institute
Co-founder of Stichting Voeding Leeft
Expert Forum on Diabetes: Genetics, Nutrition and the Future of
Diabetes Management
Swiss Re Institute 09 - 10 Oct 2017
In short my CV:
Food as Medicine:
The Challenge……..
The average age of diagnosis in the 80-90’s was
60-67 years:
What is it now?
48-55 years
Diabetes Mellitus: Short historic perspective
1500 BC
Egypt/India
Honey Urine
250 BC
“Diabetes”
300-500 CE India
Type 1 = Young
Type 2 = Overweight
1675-1776 CE
Dr. Thomas Willis
Dr. John Rollo
“Diabetes Mellitus”
1921 CE Banting & Best
Canada: Discovery of Insulin
Diabetes = Absence of INSULIN
1959 CE
Yalow & Berson
Insulin Assays
1962-1967 CE
Type 1 = Absence of insulin
Type 2 = Ineffectivity of insulin
1971-present
Treatment of Diabetes:
Through diet: reduction of
sweet foods and starch;
adding more veggies,
protein and fat
Treatment of Diabetes:
Insulin and other
medication
Diabetes Mellitus: Short historic perspective
Multiple factors contribute……….
Many nutritional factors:
The biggest one: Ultra-processed foods, 24/7!
The reality is something we don’t (or cannot) understand:
Type 2
Diabetes
Fasting glucose >7mM
No diagnosis?
Reality - Insulin resistance starts 8-10 years before Type 2
Diabetes is diagnosed:
Insulin resistance
Glucose concentration
Insulin concentration
The Insulin Issue: Continious Hyperinsulinemia = Continious
Anabolic state!
Adapted from Dr. D Ludwig
The Aim:
Balanced state = Anabolic and catabolic state.
Losing weight = More blue and less green (more fat burning)
KeerDiabetes2Om Program:Treating the person in front of the systems disease:
Started in 2014 with n = 9, increasing to n = >1900 in 2019
www.keerdiabetes2om.nl
Type 2 Diabetes = A systemic disease!
Knowledge
Keer Diabetes 2 Om.nl; The program:
DoExperience
KeerDiabetes2Om Program:Treating the person in front off the systems
disease:
www.keerdiabetes2om.nl
Fresh, unprocessed and satiating
Most recent insights from nutritional “practise-based’ research:
Lowering total carbohydrate load!
Not only for type 2 diabetes but also for CVD risk.
In short the nutritional program:
More fresh, unprocessed and satiating foods.
Higher nutritional value.
Natural fats are okay.
Maximal 3 meals a day.
Overal reduction in insulin-stimulation foods, like no-fat milk.
Reducing fast and processed carbohydrates.
No focus on caloric restriction.
A Calorie = a calorie:
Sure……..?????
Fresh, unprocessed and satiatingProcessing increases glucose and insulin load and lowers satiety!
Challenge: Nutrition with no reductionistic concept:
The nutrional matrix/balance?
Wipe cream Real butter
Doubling of
medication-free
T2DM
Reversability of Type 2 diabetes : www.keerdiabetes2om.nl> 10 years of practise-based experience:
p < 0.05
Reversability of Type 2 diabetes : www.keerdiabetes2om.nlOur results so fare: HbA1c
Reversability of Type 2 diabetes : www.keerdiabetes2om.nlMedication
p < 0.05
1. ~100% of the participants use Diabetic Medication.
2. Within 1 month 60-75% of these participants use less
medication.
3. With in 1 month 25% of the participants stopped using insulin;
55% within 3 months.
4. After 2 years: 65-75% of the participants are stil reducing or
have stopped diabetic medication completely
Reversability of Type 2 diabetes : www.keerdiabetes2om.nlMedication change:
The overall comparison to “Care as Usual”:
Synchroon database Aantal Start 6 maanden Verschil Significantie
HbA1c 3720 51,6 53,5 1,9 0,000
Nuchtere glucose 5320 7,7 7,8 0,1 ns
Gewicht 5798 85,3 85,5 0,2 0,000
Taille 59 105,5 105,2 -0,3 ns
HDL 2360 1,2 1,2 0 ns
LDL 2325 2,3 2,5 0,2 0,000
Triglyceriden 2361 1,8 1,8 0 ns
KeerDiabetes2Om Aantal Start 6 maanden Verschil Significantie
HbA1c-waarde 72 58,3 53,2 -5,2 0,000
Nuchtere glucose 57 8,9 7,7 -1,2 0,001
Gewicht 65 93,2 88,3 -4,9 0,000
Taille 60 107,7 98,9 -8,8 0,000
HDL 34 1,2 1,2 0,1 ns
LDL 41 3 2,9 -0,1 ns
Triglyceriden 38 1,9 1,5 -0,4 0,016
Wat eet jij?What do you eat?
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