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FIVE transformational themes for 2025

APAC

Spatiality

Longevity

Bell curveto barbellCapital super-abundance

Economically centered around a much less stablecore than the Euro-Atlantic of post-Cold War era.

The diminishing cost of distance and the movementtowards post-urbanization.

Redefining the ages of the stages of life.

Growing businesses bigger and smaller.

An increasingly demand-constrained growth world.

Source: Bain Macro Trends Group Analysis, 2015

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By 2025, Asia Pacific is expected to encompass more than

30% of global GDP

Source: IMF, 2011; UN Population Division, 2012; Energy Information Administration, 2013; Bain MTG Analysis

Note: Projections are from third party sources

40% of global GDP

~1 billion people

30% of global energy consumption

2025 – N. America & Europe

+30% of global GDP

~4 billion people

45% of global energy consumption

2025 – Asia Pacific

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Will changes in technology, business and society make it

possible to have low costs despite low density?

Virtual

connectivity

Shrinking

scale-points

Moving information

and ideas rather than

people and goods

Making and serving

efficiently with

smaller footprints

Transportation efficiency

Reducing the cost per mile,

especially for the last mile.• Increasing ability to

deliver urban goods

and services to

smaller decentralized

clusters of population

• Decreasing

importance of work

location as a driver of

residential location

Changing spatialeconomics

Source: Bain Macro Trends Group analysis, 2015

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Longevity is increasing for advanced economies by about

5 years every 20 years

Source: World Bank; Bain Macro Trends Group analysis

Note: Composed of 34 advanced economies as defined by the OECD, based on five-year rolling average

+5

+5

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Employees Customers EBIT per employee

1/25th

the people

4x the

customers

2x profit

per employee

New “smaller” businesses rent mass-scale from others

(e.g., Amazon) to create greater impact at higher profits

Source: Company financials; Bain Macro Trends Group Analysis, 2015

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Rapid growth of financial assets has shaped the global

economy since the 1990s

Source: International Monetary Fund; OECD; national statistics; Bain Macro Trends Group analysis

Note: All figures are in real 2010 US dollars at 2010 exchange rates

Total world financial assets

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Transformation of science

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Transformation of life sciences industry

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Drivers transforming life science ecosystem

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Score card of biotech / academia

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Evolving medical ecosystem towards 2025

Note: P4 Medicine Institute. Lee Hood, MD, PhD

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Healthcare in 2025

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Life Sciences R&D in 2025

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Partnership / Collaboration

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Partnership / Collaboration