Finzelberg GmbH & Co. KGKoblenzer Straße 48–5656626 AndernachGermanyTel: +49 2632 92400Fax: +49 2632 924 040welcome@finzelberg.com www.martin-bauer-group.com M

BG-F

BPL-

E6-0

7.20

15

Finzelberg product list Active Phytopharmaceutical Ingredients

3

Solutions from a single source

Extract philosophyWe offer a wide range of extracts from more than 100 plants – in each one you will find the concentrated force of nature and you can be sure that it corresponds to the highest quality criteria. The extracts meet both the requirements for high-quality active ingredients and raw materi-als for pharmaceutical products and the increasing statutory requirements for use in modern nutritional supplements.

Quality management systems Good Manufacturing Practices (GMP) DIN EN ISO 50001 energy management Hazard analysis and critical control

points (HACCP) Good agricultural collection practice for

most of all starting materials of herbal origin (GACP)

Service and competenceTo provide our customers with an optimal service, we are in tune with their market requirements: for the pharmaceutical market and the food sector, we have developed two different service lines as a point of departure for modern, plant-based products – phytopharmaceutical solutions and phytonutraceutical solutions. Irrespective of the sector in which you operate, we always offer you custom-made, commercially viable solutions that naturally meet statutory requirements.

tailor-made solutions

Extracts, concepts and regulatory support

Pharma documentation Our worldwide network with renowned partners from the health industry offers the ideal conditions for providing our business partners with innovative extracts exactly matched to their needs as well as modern health concepts as complete solutions.

Our products and services in details: Plant extract as active phytopharmaceu-

tical ingredient (API) Documentation for the extracts matched

to the regulations of the market regions Dossiers for herbal medicinal products Product concepts, including pharma

dossiers in CTD-format or documentation Medicinal premixes, including pharma

dossiers in CTD format or documentation Certificate of suitability to the monographs

of the European Pharmacopoeia (CEP)

There is always more

Heart & Veins

Extract Application Form Example for possible Indication

Crataegi folium cum floreDry extract from Hawthorn leaf and flower, DER: 4-7:1, methanol 70 % (V/V)

Coated Tablet Relief of symptoms of nervous cardiac complaints such as palpitations

Crataegi folium cum floreDry extract from Hawthorn leaf and flower, DER: 4-7:1, ethanol 45 % (V/V)

Coated Tablet Relief of symptoms of nervous cardiac complaints such as palpitations

Crataegi folium cum floreDry extract from Hawthorn leaf and flower,DER: 4-7:1, ethanol 45 % (V/V)

Coated Tablet Relief of symptoms of nervous cardiac complaints such as palpitations

Crataegi folium cum flore (plus Mg-Aspartate, K-Aspartate) Dry extract of Hawthorn leaf with flower, DER: 4-7:1, methanol 70 % (V/V)

Coated Tablet Relief of mild cardiac injuries (senile heart)

Vitis viniferae foliumDry extract from Red vine leafDER: 4-6:1, water

Coated Tablet Treatment of chronic venous insufficiency, which is characterised by swollen legs, varicose veins, a feeling of heaviness, pain, tiredness, itching, tension and cramps in the calves

Digestion

Extract Application Form Example for possible Indication

Cynarae folium Dry extract from Artichoke leaf, DER 4-6:1, water

Capsule Relief of digestive disorders such as dyspepsia with a sensation of fullness, bloating and flatulence

Dossier list

Your success is our goal, which is why Finzelberg focuses on “tailor-made solutions”, referring to the accurate implementation of your customer specific requirements.

the nature network® - partnership and international competenceIntegrated within Martin Bauer Group and the nature network®, Finzelberg’s custom-ers also benefit from the synergies offered by a global group of companies.

Worldwide, about 30 companies and over 3000 employees are closely networked together in the nature network®. Thus we can guarantee the secure supply of raw material and offer our customers a multi-plication of performance in many areas.

Cough & Cold

Extract Application Form Example for possible Indication

Hederae foliumDry extract from Ivy leaf,4-8:1, ethanol 30 % (m/m)

Syrup Used as an expectorant in case of productive cough

Hederae foliumDry extract from Ivy leaf,DER: 4-8:1, ethanol 30 % (m/m)

Thin Film Used as an expectorant in case of productive cough

Pelargonii radixLiquid extract from Pelargonium root, DER: 8-10:1, ethanol 15 % (V/V)

Oral Liquid Symptomatic treatment of common cold

Plantaginis lanceolatae foliumDry extract from Plantain leaf, DER: 4-6:1, ethanol 20 % (m/m)

Effervescent Tablet Demulcent for the symptomatic treatment of oral or pharyngeal irritations and associated dry cough

Plantaginis lanceolatae foliumLiquid extract from Plantain leaf,DER: 1-1, ethanol 25 % (V/V)

Syrup For the symptomatic treatment of oral or pharyngeal irritations and associated dry cough

from your herbal expert

Prof

essional guidance

5

Urology

Extract Application Form Example for possible Indication

Betulae foliumDry extract from Birch leaf DER: 4-8:1, water

Coated Tablet Treatment to increase flushing of the urinary tract

CNS (Stress, Mood, Sleep)

Extract Application Form Example for possible Indication

Eleutherococci radixDry extract from Siberian ginseng root, DER: 16-25:1, ethanol 30 % (V/V)

Capsule For symptoms of asthenia such as fatigue and weakness

Hyperici herbaDry extract from St. John’s wort, DER: 3.5-6:1, ethanol 60 % (m/m)

Coated Tablet Short term treatment of symptoms in mild depressive disorders

Hyperici herba / Valerianae radixDry extract from St. John’s wort, DER: 3.5-6:1, ethanol 60 % (m/m) / Dry extract from Valerian root, DER: 3-6:1, ethanol 70 % (V/V)

Coated Tablet Relief of slightly low mood, mild anxiety and sleep disturbances due to symptoms of mild anxiety

Passiflorae herbaDry extract from Passion flower, DER: 5-7:1, ethanol 50 % (V/V)

Coated Tablet Relief of mild symptoms of mental stress and to aid sleep

Passiflorae herba / Valerianae radixDry extract from Passion flower,DER: 5-7:1; ethanol 50 % (V/V)Dry extract from Valerian root,DER: 3-6:1, ethanol 70 % (V/V)

Coated Tablet Relief of sleep disturbances due to symptoms of mild anxiety

Rhodiolae roseae rhizoma et radixDry extract from Rhodiola rosea rhizome and root,DER: 1,5-5:1, ethanol 70 % (V/V)

Coated Tablet Relief of symptoms of stress, such as fatigue and sensation of weakness

Valerianae radix

Dry extract from Valerian root, DER: 3-6:1, ethanol 70 % (V/V)

Coated Tablet Relief of mild nervous tension and sleep disorders

Valerianae radixDry extract from Valerian root, DER: 3-6:1, ethanol 70 % (V/V)

Coated Tablet Relief of mild nervous tension and sleep disorders

Valerianae radix / Melissae folium / Passiflorae herbaDry extract from Valerian root,DER: 3-6:1, ethanol 70 % (V/V)Dry extract from Melissa leaf, DER: 4-6:1, methanol 30 % (V/V)Dry extract from Passion flower, DER: 5-7:1, ethanol 50 % (V/V)

Coated Tablet Temporary relief of symptoms of mild anxiety, to aid sleep and for mild digestive complaints, such as bloating and flatulence

Joint Health

Extract Application Form Example for possible Indication

Harpagophyti radix Dry extract from Devil’s claw root, DER: 1.5-2.5:1, water

Coated Tablet Relief of minor articular pain

Sexuality

Extract Application Form Example for possible Indication

Damianae folium Dry extract from Damiana leaf DER: 5-7:1, ethanol 90 % (V/V)

Coated Tablet Used as an aphrodisiac for waning sexual desire (men & women)

Women’s Health

Extract Application Form Example for possible Indication

Agni casti fructus Dry extract from Chaste tree fruit, DER: 7-13:1, ethanol 60 % (m/m)

Coated Tablet Relief of minor symptoms in the days before menstruation

Cimicifugae rhizomaDry extract from Black cohosh, DER: 4.5-8.5:1, ethanol 60 % (V/V)

Coated Tablet Relief of symptoms of the menopause, such as hot flashes, night sweats and temporary changes in mood

Hyperici herba / Cimicifugae rhizomaDry extract from St. John’s wortDER: 3.5-6:1, ethanol 60 % (m/m)Dry extract from Black cohoshDER: 4.5-8.5:1, ethanol 60 % (V/V)

Coated Tablet Relief of symptoms of the menopause, including hot flushes, night sweats, slightly low mood and mild anxiety

Millefolii herba Dry extract from Yarrow, DER: 5-10:1, water

Coated Tablet Symptomatic treatment of minor spasm associated with menstrual periods

Men’s Health

Extract Application Form Example for possible Indication

Sabalis serrulatae fructus Soft extract from Saw palmetto fruit,DER: 9-11:1, ethanol 96 % (V/V)

Softgel Capsule Relief of lower urinary tract symptoms related to benign prostatic hyperplasia

Urticae radix Dry extract from Nettle root, DER: 7-14:1, methanol 20 % (V/V)

Coated Tablet Relief the symptoms of urinary tract discomfort for men who have an enlarged prostate

7

Skin

Extract Possible wording for claims

Cisti ECCe20Cisti

Protects body and skin against oxidative damages

Cisti ECCe60Cisti

Protects body and skin against oxidative damages

Sports

Extract Possible wording for claims

FB300 Golden RootRhodiolae roseae rhizoma et radix

For a better physical and mental recovery

FB9463 ofixPrickly Pears(Opuntia ficus indica)

Helps physical recovery after sport exercises Increases total muscle creatine content

Joint health

Extract Possible wording for claims

motion plus FB9440 Meditterranean rose hip + collagen hydrolysate + vitamin C

Maintenance of normal function during and after extreme physical exercise Protection of normal collagen formation

FB9440 Rose Hip Extract from Mediterranean rose hip skins

Maintenance of normal function during and after extreme physical exercise

Sexuality

Extract Possible wording for claims

FB320 damianaDamina (Turnera)

Positive influence on sexual performance for men & women

Women’s Health

Extract Possible wording for claims

FB1521 Green Hops Humuli Lupuli

Helps women to maintain a calm and comfortable menopause (hot flushes, sweating, restlessness, irritation)

CNS (Stress, Mood, Sleep)

Extract Possible wording for claims

FB2323 Greek Montain TeaSideritis

Positive influence on neurodegenerative diseases as mild cognitive impairment

FB6285 Green TeaTheae sinensis

Protects against oxidative damages Improves attention and cognition

FB300 Golden RootRhodiola roseae rhizoma et radix

Better cognitive and mental performance

phytonutraceutical solutions Functional ingredients and concepts

Remark: This brochure is available in various countries. Hence it may contain statements not applicable to a region and its regulations. The marketer of any ingredient or finished product has to ensure that the product category and the claims made are legal and comply with the other regulations in the sales region.

Extracts with 3.2.S quality part on request.

FB4443 Ginkgo dry extract, refined and quantified Ph. Eur.

FB1993 Valerian dry hydroalcoholic extract Ph. Eur.

FB2852 Saw palmetto extract Ph. Eur.

phytopharmaceutical solutionsExtracts with certificates of suitability (CEP)

9

Extract list

Remark: This list is not exhaustive – please contact your partner at Finzelberg for any requirement or detailed information.

Cough & Cold

Herbal Raw Material Botanical Name Common Name Plant part Use

Althaeae radix Althaea officinalis L. Marshmallow Root Dry cough

Cisti herba Cistus creticus L. ssp. eriocephalus (VIV.) Pink Rock-Rose (Cisti) Herb Immune stimulant

Echinaceae herba Echinacea purpurea (L.) Moench Purple Coneflower Herb Immune stimulant

Hederae folium Hedera helix L. Ivy Leaf Expectorant

Liquiritiae radix Glycyrrhiza glabra L. / inflata Bat. / uralensis Fisch. Liquorice Root Expectorant

Pelargonii radix Pelargonium sidoides DC / reniforme Curt. Pelargonium Root Common cold

Plantaginis lanceolatae folium Plantago lanceolata L. s.l. Ribwort Plantain Leaf Dry cough

Primulae radix Primula veris L. / elatior Hill. Primrose Rhizome & root Expectorant

Salviae officinalis folium Salvia officinalis L. Sage Leaf Mouth / Sore Throat

Thymi herba Thymus vulgaris L. / zygis L. Thyme Herb Expectorant

Digestion

Herbal Raw Material Botanical Name Common Name Plant part UseAloe capensis Aloe ferox Mill. Aloe Juice Laxative

Belladonnae folium Atropa belladonna L. Belladonna Leaf Spasmolytic

Cynarae folium Cynara cardunculus L. Artichoke Leaf Bile flow

Frangulae cortex Rhamnus frangula L. (Frangula alnus Miller) Alder Buckthorn Bark Laxative

Fumariae herba Fumaria officinalis L. Fumitory Herb Bile flow

Fucus vesiculosus, thallus Fucus vesiculosus L. / serratus L. / Ascophyllum nodosum

Bladderwrack/ Kelp Thallus Diuretic

Rhamni purshianae cortex Rhamnus purshiana DC Cascara Bark Laxative

Rhei radix Rheum palmatum L. / officinale Baill. Rhubarb Root Laxative

Sennae fructus Cassia senna L. Senna Fruit Laxative

Silybi mariani fructus Silybum marianum L. Gaertner Milk Thistle Fruit Liver

Taraxaci officinalis herba cum radice Taraxacum officinale F.H. Wigg. Dandelion Herb with root Bile flow

Taraxaci officinalis radix Taraxacum officinale F.H.Wigg. Dandelion Root Bile flow

Xysmalobii radix Xysmalobium undulatum (L.) R. Br. Uzara Root Diarrhoea

Heart & Veins

Herbal Raw Material Botanical Name Common Name Plant part Use

Allii sativi bulbus Allium sativum L. Garlic Bulb Cardiovascular health

Cinnamomi cortex Cinnamomum verum J.Presl. Cinnamon Bark Blood glycose management

Crataegi folium cum flore Crataegus species Hawthorn Leaf and flower Cardiac stimulant

Crataegi fructus Crataegus species Hawthorn Fruit Cardiac stimulant

Hippocastani semen Aesculus hippocastanum L. Horse Chestnut Seed Varicose veins

Meliloti herba Melilotus officinalis (L.) Lam Sweet clover Herb Varicose veins

Oleae folium Olea europaea L. Olive Leaf Hypertension

Rusci rhizoma Ruscus aculeatus L. Butcher‘s Broom Rhizome Haemorrhoids care

Vitis viniferae semen Vitis vinifera L. Grape Seed Seed Vasoprotection

Vitis viniferae folium Vitis vinifera L. Red vine Leaf Leaf Varicose veins

CNS (Stress, Mood, Sleep)

Herbal Raw Material Botanical Name Common Name Plant part Use

Eleutherococci radix Eleutherococcus senticosus (Rupr. et Maxim.) Maxim Siberian Ginseng Root Adaptogen

Ginkgonis Ginkgo biloba L. Ginkgo Leaf Dementia

Ginseng radix Panax ginseng C.A. Meyer Ginseng Root Adaptogen

Hyperici herba Hypericum perforatum L. St. John‘s Wort Herb Anti depression

Lupuli flos Humulus lupulus L. Hop Strobile Female inflorescence

Sedative

Melissae folium Melissa officinalis L. Lemon Balm Leaf Sedative

Rhodiolae roseae rhizoma et radix Rhodiola rosea L. Arctic Root (in US) Golden Root

Rhizome & root Adaptogen

Passiflorae herba Passiflora incarnata L. Passion Flower Herb Sedative

Kava-Kava rhizoma Piper methysticum G. Forster Kava-Kava Rhizom Anti-anxiety

Sideritis herba Sideritis spec. L. Greek Mountain Tea Herb Cognition / Memory

Theae viridis folium Camellia sinensis (L.) Kuntze Green Tea Leaf Sleeping behavior

Valerianae radix Valeriana officinalis L. s.l. Valerian Root Sedative

11

Remark: This list is not exhaustive – please contact your partner at Finzelberg for any requirement or detailed information.

Women’s Health

Herbal Raw Material Botanical Name Common Name Plant part Use

Agni casti fructus Vitex agnus-castus L. Chaste Tree Fruit Menopausal symptoms

Cimicifugae rhizoma Actaea racemosa L. (Cimicifuga racemosa (L.) Nutt.) Black Cohosh Rhizome Menopausal symptoms

Sports

Herbal Raw Material Botanical Name Common Name Plant part Use

Opuntiae ficus cladodia / pericarpium Opuntia ficus indica (L.) Mill. Prickly Pears Pads (cladodes) / Fruit skins

Physcial sports recovery

Skin

Herbal Raw Material Botanical Name Common Name Plant part Use

Centellae asiaticae herba Centella asiatica (L.) Urban Centella, Gotu Kola Herb Wound healing

Pandani fructus Pandanus conoideus Lam. Pandanus Fruit Inflammatory disorders Sexuality

Herbal Raw Material Botanical Name Common Name Plant part Use

Damianae folium Turnera diffusa Willd. Damiana Leaf / Stem Aphrodisiac

Muscle pain

Herbal Raw Material Botanical Name Common Name Plant part Use

Capsici fructus Capsicum frutescens L. Cayenne Pepper Fruit Antirheumatic

Joint Healt

Herbal Raw Material Botanical Name Common Name Plant part Use

Harpagophyti radix Harpagophytum procumbens DC / zeyheri Decne. Devil‘s Claw Root Antirheumatic

Rosae pseudo fructus Cynosbati fructus Rose hip Fruit Arthrosis

Salicis cortex Salix-species Willow Bark Pain Relief

Urticae folium Urtica dioica / urens L. Nettle Leaf Antirheumatic / Diuretic

Zingiberis rhizoma Zingiber officinale Roscoe Ginger Rhizome Antirheumatic / Motion sickness

Urology

Herbal Raw Material Botanical Name Common Name Plant part Use

Asparagus radix Asparagus officinalis L. Common Asparagus Shoot Diuretic

Betulae folium Betula pendula Roth / Pubescens Ehrh Birch Leaf Diuretic

Cucurbitae semen Cucurbita pepo L. Pumpkin Seed Prostata

Equiseti herba Equisetum arvense L. Horsetail Stem Diuretic

Fucus vel Ascophyllum Fucus vesiculosus L. / serratus L. / Ascophyllum nodosum

Bladderwrack / Kelp Thallus Diuretic

Ononidis radix Ononis spinosa L. Restharrow Root Diuretic

Orthosiphonis folium Orthosiphon stamineus Benth. Java tea Leaf Diuretic

Uvae ursi folium Arctostaphylos uva-ursi (L.) Spreng. Bearberry Leaf Infection

Men’s Health

Herbal Raw Material Botanical Name Common Name Plant part Use

Sabalis serrulatae fructus Serenoa repens (Bartram) Small. Saw Palmetto Fruit Prostata

Urticae radix Urtica dioica / urens L. Nettle Root Prostata