Figure 2

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a c Figure 2 IL-22 IL-17A + FICZ AhR -/- B6 FICZ ctrl mRNA level to HPRT (x10 -3 ) IL-17A IL-17F IL-22 CYP1A1 AHR ROR IL-17F IL-17A + FICZ b 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 2.0 38 35.7 24.3 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 3.5 60.2 20.3 16 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 3.6 25.1 32.1 39.2 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 2.6 21.5 33.1 42.7 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 65.1 17.7 0.8 16.4 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 32 0.2 0.3 67.4 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 58.2 0.5 0.1 41.1 10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4 34.2 0.1 0.1 65.6 0 5000 10000 15000 20000 25000 0 5000 10000 15000 20000 25000 Th0 Th1 Th2 iTreg Th17 Th0 Th1 Th2 iTreg Th17 0 100 200 300 400 500 600 Th0 Th1 Th2 iTreg Th17 0 100 200 300 400 500 600 Th0 Th1 Th2 iTreg Th17 0 20 40 60 80 Th0 Th1 Th2 iTreg Th17 0 20 40 60 80 100 120 Th0 Th1 Th2 iTr e g Th17

description

4. 4. 10. 10. 4. 10. 4. 65.1. 17.7. 10. 32. 0.2. 3. 3. 10. 10. 3. 10. 600. 3. 10. 500. 80. 2. 400. 10. 2. 2. 10. 10. 2. 10. 60. 300. 200. 1. 10. 40. 1. 10. 1. 1. 100. 10. 10. 120. 16.4. 0.8. 20. 0. 67.4. 0.3. 100. 0. 10. 0. 10. 80. 3. 0. - PowerPoint PPT Presentation

Transcript of Figure 2

Page 1: Figure 2

a

c

Figure 2

IL-22

IL-1

7A

+ FICZ

Ah

R-/

-B

6

FICZctrl

mR

NA

lev

el t

o H

PR

T (

x10-3

)

IL-17A IL-17F IL-22

CYP1A1AHRROR

IL-17F

IL-1

7A

+ FICZb

100 101 102 103 104100

101

102

103

104

2.0 38

35.724.3100 101 102 103 104

100

101

102

103

104

3.5 60.2

20.316

100 101 102 103 104100

101

102

103

104

3.6 25.1

32.139.2100 101 102 103 104

100

101

102

103

104

2.6 21.5

33.142.7

10 0 10 1 10 2 10 3 10 410 0

10 1

10 2

10 3

10 4

65.1 17.7

0.816.4

10 0 10 1 10 2 10 3 10 410 0

10 1

10 2

10 3

10 4

32 0.2

0.367.4

10 0 10 1 10 2 10 3 10 410 0

10 1

10 2

10 3

10 4

58.2 0.5

0.141.1

10 0 10 1 10 2 10 3 10 410 0

10 1

10 2

10 3

10 4

34.2 0.1

0.165.6

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020406080

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100120

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