Figure 1
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Figure 1 Man 6P receptors -44 34 K 1 348 Asp Man6P Man6P 231 Asp 33 14 K pro 4 K catalytic site NH2 COOH Asn70 Asn199
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Man 6P receptors. Man6P. Man6P. Asn70. Asn199. pro 4 K. NH2. COOH. 14 K. 34 K. Asp. Asp. 1. - 44. 348. 33. 231. catalytic site. Figure 1. Tumor micro-environment. Activation at acidic pH. Secretion. Endocytosis. 52K. 52K. 52K. 52K. 48K. M6P receptors - PowerPoint PPT Presentation
Transcript of Figure 1
Figure 1
Man 6P receptors
-44
34 K
1 348Asp
Man6P Man6P
231Asp33
14 Kpro4 K
catalytic site
NH2 COOHAsn70 Asn199
ERGolgi
Endosomes Lysosomes
Cytosolic cath-D
Transcription ?
Nucleus
M6P receptors and other proteins
Apoptosis
Endocytosis
Degradation
Secretion
Activation at acidic pH
Tumor micro-environment
52K52K
52K 52K
48K
34K
14
K
34K
14
K
Figure 2