Fig.47 Effect of Alcoholic extracts of Barleria prionities - Shodhganga
129
Barleria prionities - Results Institute of Pharmaceutical Technology, SPMVV, Tirupati. Fig.47 Effect of Alcoholic extracts of Barleria prionities root on the Spontaneous motor activity scores in MPTP treated mice. 1st day 3rd day 6th day 0 100 200 300 400 500 Control MPTP 100mg/kg BPE+MPTP 200mg/kg BPE+MPTP 300mg/kg BPE+MPTP 300mg/kg BPE *** *** *** *** *** *** *** *** *** *** *** *** *** +++ +++ +++ +++ +++ +++ +++ +++ +++ Values are expressed as Mean±SEM(n=6); ***(P<0.001) Vs Control group; +++(P0.001) Vs MPTP group. GROUPS Spontaneous motor activity scores
Transcript of Fig.47 Effect of Alcoholic extracts of Barleria prionities - Shodhganga
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.47 Effect of Alcoholic extracts of Barleria prionities root on
the Spontaneous motor activity scores in MPTP treated mice.
1st day 3rd day 6th day0
100
200
300
400
500
Control MPTP 100mg/kg BPE+MPTP 200mg/kg BPE+MPTP
300mg/kg BPE+MPTP 300mg/kg BPE
*** *** *** *** ***
***
*** ****** ***
***
******
++++++
++++++
+++
++++++
++++++
Values are expressed as Mean±SEM(n=6);
***(P<0.001) Vs Control group;
+++(P0.001) Vs MPTP group.
GROUPS
Sp
on
tan
eo
us m
oto
r acti
vit
y s
co
res
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.48 Effect of Alcoholic extract of Barleria prionities root on
Gripstrength (Rota Rod test) in MPTP treated mice.
0
50
100
150
Control MPTP 100mg/kg BPE+MPTP 200mg/kg BPE+MPTP
300mg/kg BPE+MPTP 300mg/kg BPE
****** *** *** ***
***
******
***
****** *****
**+++
++++++
+++++++++++++++
+++++++++
Values are expressed as Mean±SEM(n=6);
** (P<0.01), ***(P<0.001) Vs Control group;
+++(P<0.001) Vs MPTP group.
GROUPS
Rete
nti
on
tim
e in
seco
nd
s
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.49 Effect of Alcoholic extract of Barleria prionities root on
Alertness (Hole Board test) in MPTP treated mice.
1st day 3rd day 6th day0
20
40
60
Control MPTP 100mg/kg BPE+MPTP 200mg/kg BPE+MPTP
300mg/kg BPE+MPTP 300mg/kg BPE
*** ***
*** ***
***
******
***
***
****** ***
+++
+++++++++
+++
++++++
++++++
++++
Values are expressed as Mean±SEM(n=6);
***(P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
GROUPS
Nu
mb
er o
f h
ead
dip
pin
gs
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.9 Effect of Alcoholic extract of Canavalia gladiata seedon the Spontaneous motor activity (score).
1st day 3rd day 6th day0
100
200
300
400
500
Control MPTP 100mg/kgCGE+MPTP 200mg/kg CGE+MPTP
300mg/kgCGE+MPTP 300mg/kgCGE
*** *** *** *** ***
***
******
*** ***
***
******
*** ***
+ ++ +++
++++++
+++ ++++++
+++
++++++
Values are expressed as mean±SEM (n=6);
***(P<0.001) Vs Control group;
+ (P<0.05), ++ (P<0.01), +++ (P<0.001) Vs MPTP group.
GROUPS
Sp
on
tan
eo
us m
oto
r acti
vit
y s
co
res
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.10 Effect of Alcoholic extract of Canavalia gladiata on
Gripstrength (Rota Rod test) in MPTP treated mice.
1st day 2nd day 3rd day0
50
100
150
Control MPTP 100mg/kg CGE+MPTP 200mg/kg CGE+MPTP
300mg/kg CGE+MPTP 300mg/kg CGE
******
******
Values are expressed as Mean±SEM (n=6);
* (P<0.01), *** (P<0.001) Vs Control group;
+ (P<0.05), ++ (P<0.01),+++ (P<0.001) Vs MPTP group.
***
***
***
****** *
+++++++++
+++
+++++++++
+++
+++
*+++
GROUPS
Rete
nti
on
tim
e in
seco
nd
s
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.11 Effect of Alcoholic extract of Canavalia gladiata seed on
Alertness (Hole board test) in MPTP treated mice.
1st day 3rd day 6th day
0
20
40
60
Control MPTP 100mg/kg CGE+MPTP 200mg/kg CGE+MPTP
300mg/kg CGE+MPTP 300mg/kg CGE
Values are expressed as Mean±SEM(n=6);
* (P<0.01), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
***
***
*** ***
***
***
***
***
**+++
++++++
++++++
+++
+++
++++++
+++
+++
++
GROUPS
Nu
mb
er
of
head
dip
pin
gs
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.84 Effect of Alcoholic extracts of Prosopis chilensis seeds on
the Spontaneous motor activity scores in MPTP treated mice.
1st day 3rd day 6th day0
100
200
300
400
500
Control MPTP 100mg/kg PCE+MPTP 200mg/kg PCE+MPTP
300mg/kg PCE+MPTP 300mg/kg PCE
Values are expressed as Mean±SEM(n=6);
***(P<0.001) Vs Control group;
+++(P<0.001) Vs MPTP group.
*** *** *** ******
***
*** ****** ***
***
******
++++++
++++++
+++++++++
++++++
GROUPS
Sp
on
tan
eo
us
mo
tor a
cti
vit
y s
co
res
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.85 Effect of Alcoholic extracts of Prosopis chilensis seeds on
the Gripstrength (Rota rod test) in MPTP treated mice.
1st day 3rd day 6th day0
50
100
150
Control MPTP 100mg/kg PCE+MPTP
200mg/kg PCE+MPTP 300mg/kg PCE+MPTP 300mg/kg PCE
*** ****** *** ***
***
****** ***
***
*** ******
***+++
+++++++++
++++++
++++++
+++++++ *
Values are expressed as Mean±SEM(n=6);
* (P<0.05), ***(P<0.001) Vs Control group;
+ (P<0.05), +++(P<0.001) Vs MPTP group.
GROUPS
Rete
nti
on
tim
e i
n s
eco
nd
s
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.86 Effect of Alcoholic extracts of Prosopis chilensis seeds on
the Alertness (Hole board test) in MPTP treated mice.
1st day 3rd day 6th day0
20
40
60
Control MPTP 100mg/kg PCE+MPTP
200mg/kg PCE+MPTP 300mg/kg PCE+MPTP 300mg/kg PCE
Values are expressed as Mean±SEM(n=6);
***(P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
******
******
***
****** ***
***
*** ******
+++
+++++++++
++++++
++++++
++++
+
GROUPS
Nu
mb
er o
f h
ead
dip
pin
gs
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.40 Effect of Alcoholic extract of roots of Barleria prionities
on spontaneous motor activity
0
200
400
600
Control 100mg/kg AEBP 200mgkg AEBP 300mg/kg AEBP
**
***
GROUPS
Sp
on
tan
eo
us m
oto
r acti
vit
y s
co
re
Values are expressed as Mean ±SEM (n=6);
*(P<0.05), **(P<0.01,) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.41 Effect of Alcoholic extract of Roots of Barleria prionities on
Analgesia (Eddys hot plate).
0
2
4
6
Control 100mg/kg AEBP 200mg/kg AEBP 300mg/kg AEBP
GROUPS
Reacti
on
tim
e in
seco
nd
s
Values are expressed as Mean ±SEM (n=6);
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.42 Effect of Alcoholic extract of roots of Barleria prionities on
motor co-ordination (Rota Rod test)
0
50
100
150
200
250
Control 100mg/kg AEBP 200mg/kg AEBP 300mg/kg AEBP
**
**
GROUPS
Rete
nti
on
tim
e in
seco
nd
s
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.43 Effect of Alcoholic extract of roots of Barleria prionities on
immobility time in Tail suspension test.
0
50
100
150
200
250
Control 100mg/kg AEBP 200mgkg AEBP 300mg AEBP
**
**
GROUPS
Du
rati
on
of
imm
ob
ilit
y t
ime in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.44 Effect of Alcoholic extract of roots of Barleria prionities
on immobility time in Forced swimming test.
0
20
40
60
80
Control 100mg/kg AEBP 200mg/kg AEBP 300mg/kg AEBP
** **
**
GROUPS
Du
rati
on
of
imm
ob
ilit
y t
ime in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.45 Effect of Alcoholic extract of roots of Barleria prionities on
swimming time in Forced swimming test.
0
50
100
150
200
250
Control 100mg/kg AEBP 200mg/kg AEBP 300mg/kg AEBP
**** **
GROUPS
Du
rati
on
of
sw
mm
ing
tim
e in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.46 Effect of Alcoholic extract of roots of Barleria prionities on
Alertness (Hole Board test).
0
20
40
60
80
100
Control 100mg/kg AEBP 200mg/kg AEBP 300mg/kg AEBP
**
*
GROUPS
Nu
mb
er o
f h
ead
dip
pin
gs
Values are expressed as Mean ±SEM (n=6);
*(P<0.05), **(P<0.01) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig 2.Effect of Alcoholic extract of seeds of Canavalia gladiata on
the spontaneous motor activity.
0
100
200
300
400
500
Control 100mg AECG 200mg AECG 300mg AECG
GROUPS
**
**
Sp
on
tan
eo
us m
oto
r acti
vit
y s
co
res
Values are expressed as M± SEM (n=6);
** (P<0.01) Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.3 Effect of Alcoholic extract of seeds of Canavalia gladiata on
analgesia (Eddys hot plate test).
0
1
2
3
4
control 100mg AECG 200mg AECG 300mg AECG
GROUPS
Reacti
on
tim
e in
seco
nd
s
Values are expressed as Mean ±SEM (n=6);
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.4 Effect of Alcoholic extract of seeds of Canavalia gladiata on
motor co-ordination ( Rota Rod test)
0
50
100
150
200
250
control 100mg AECG 200mg AECG 300mg AECG
**
*
GROUPS
Rete
nti
on
tim
e in
seco
nd
s
Values are expressed as Mean ±SEM (n=6);
* (P<0.05), **(P<0.01,) Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.5 Effect of Alcoholic extract of seeds of Canavalia gladiata on
immobility time in forced swimming test
0
20
40
60
80
control 100mg AECG 200mg AECG 300mg AECG
****
**
GROUPS
Du
rati
on
of
imm
ob
ilit
y t
ime in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs Control group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.6 Effect of Alcoholic extract of seeds of Canavalia gladiata on Swimming
time in forced swimming test.
0
100
200
300
control100mg AECG 200mg AECG 300mg AECG
** ** **
GROUPS
Du
rati
on
of
sw
mm
ing
tim
e in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs Control group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.7 Effect of Alcoholic extract of seeds of Canavalia gladiata on
immobility time in Tail suspension test
0
50
100
150
200
250
control 100mg AECG 200mg AECG 300mg AECG
**
**
**
GROUPSDu
rati
on
of
imm
ob
ilit
y t
ime in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs Control group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.8 Effect of Alcoholic extract of seeds of Canavalia gladiata
on alertness( Hole Board test).
0
20
40
60
control 100mg AECG 200mg AECG 300mg AECG
**
**
GROUPS
Nu
mb
er o
f h
ead
dip
pin
gs
Values are expressed as Mean ±SEM (n=6);
** (P<0.01) Vs Control group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 127 Effect of Alcoholic extract of root bark of Capparis zeylanica
on the spontaneous motor activity.
0
100
200
300
Control 100 mg/kg AECZ 200 mg/kg AECZ 300 mg/kg AECZ
*
****
Groups
Sp
on
tan
eo
us
mo
tor a
cti
vit
y s
co
re
Values are expressed as mean ±SEM of 6 animals
*(P<0.05), **(P<0.01) Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 128 Effect of Alcoholic extract of root bark of Capparis zeylanica
on analgesia (Eddys Hot plate test).
0.0
0.5
1.0
1.5
2.0
2.5
Control 100 mg/kg AECZ 200 mg/kg AECZ 300 mg/kg AECZ
Groups
Tim
e i
n s
eco
nd
s
Values are expressed as mean ±SEM of 6 animals
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 129 Effect of alcoholic extract of root bark of Capparis zeylanica
on motor co-ordination (Rota Rod test)
0
50
100
150
Control 100 mg/kg AECZ 200 mg/kg AECZ 300 mg/kg AECZ
** ** **
Groups
Tim
e i
n s
eco
nd
s
Values are expressed as mean ± SEM of 6 animals;
**P<0.01 Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 130 Effect of Alcoholic extract of root bark of Capparis zeylanica
on immobility time in forced swimming test.
0
50
100
150
Control 100 mg/kg AECZ 200 mg/kg AECZ300 mg/kg AECZ
**
** **
Groups
Du
rati
on
of
imm
ob
ilit
y t
ime i
n s
ec
Values are expressed as mean ± SEM of 6 animals,
**P<0.01 Vs Control group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 131 Effect of Alcoholic extract of root bark of Capparis zeylanica
on swimming time in forced swimming test.
0
50
100
150
Control 100 mg/kg AECZ 200 mg/kg AECZ 300 mg/kg AECZ
** **
**
Groups
Du
rati
on
of
sw
imm
ing
in
sec
Values are expressed as Mean ± SEM of 6 animals;
**P<0.01 Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 134 Effect of Alcoholic extract of root bark of Capparis zeylanica
on alertness (Hole Board test).
0
5
10
15
20
25
Control 100 mg/kg AECZ 200 mg/kg AECZ 300mg/kg AECZ
**
** **
Groups
Nu
mb
er
of
head
dip
pin
gs
Values are expressed as mean ±SEM of 6 animals,
**P<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.132 Effect of Alcoholic extract of root bark of Capparis zeylanica
on climbing time in forced swimming test.
0
50
100
150
Control 100 mg/kg AECZ 200 mg/kg AECZ 300 mg/kg AECZ
** ** **
Groups
Du
rati
on
of
cli
mb
ing
in
seco
nd
s
Values are expressed as mean ±SEM of 6 animals;
**P<0.01 Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.133 Effect of Alcoholic extract of root bark of Capparis zeylanica
on immobility time in tail suspention test.
0
50
100
150
200
250
Control 100 mg/kg AECZ 200 mg/kg AECZ 300 mg/kg AECZ
** ** **
Groups
Du
rati
on
of
imm
ob
ilit
y t
ime i
n s
ec
Values are expressed as mean ±SEM of 6 animals;
**P<0.01 Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 115 Effect of Alcoholic extract of root of Dichrostachys cinerea
on the spontaneous motor activity.
0
100
200
300
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
**** **
Groups
sp
on
tan
eo
us m
oto
r acti
vit
y s
co
re
Values are expressed as mean ±SEM of 6 animals,
**p<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.116 Effect of Alcoholic extract of root of Dichrostachys cinerea
on analgesia (Eddys Hot plate test)
0
1
2
3
4
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
Groups
Tim
e i
n s
eco
nd
s
Values are expressed as mean ±SEM of 6 animals
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 117 Effect of alcoholic extract of root of Dichrostachys cinerea
on the motor co-ordination (Rota Rod test)
0
50
100
150
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
****
**
Groups
Tim
e i
n s
eco
nd
s
Values are expressed as mean ±SEM of 6 animals,
**p<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.118 Effect of Alcoholic extract of root of Dichrostachys cinerea
on immobility time in forced swimming test.
0
50
100
150
200
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
** ** **
Groups
Tim
e i
n s
eco
nd
s
Values are expressed as mean ±SEM of 6 animals,
**P<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 119 Effect of Alcoholic extract of root of Dichrostachys cinerea
on swimming time in forced swimming test
0
50
100
150
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
**** **
Groups
Tim
e i
n s
eco
nd
s
Values are expressed as mean ±SEM of 6 animals,
**p<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.120 Effect of Alcoholic extract of root of Dichrostachys cinerea
on climbing time in forced swimming test.
0
10
20
30
40
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
**** **
Groups
Tim
e i
n s
eco
nd
s
Values are expressed as mean ±SEM of 6 animals,
**P<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 121 Effect of Alcoholic extract of root of Dichrostachys cinerea
on immobility time in tail suspension test.
0
50
100
150
200
250
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
**
****
Groups
Du
rati
on
of
imm
ob
ilit
y t
ime in
sec
Values are expressed as mean ±SEM of 6 animals,
**p<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.122 Effect of Alcoholic extract of root of Dichrostachys cinerea
on alertness (Hole Board test).
0
5
10
15
20
25
Control 100 mg/kg AEDC 200 mg/kg AEDC 300 mg/kg AEDC
****
**
Groups
Nu
mb
er
of
head
dip
pin
gs
Values are expressed as mean ±SEM of 6 animals,
**p<0.01 Vs Control Group
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.78 Effect of Alcoholic extract of roots of Prosopis chilensis on
spontaneous motor activity
0
100
200
300
400
Control 100mg/kg AEPC 200mg/kg AEPC 300mg/kg AEPC
**
*
GROUPS
Sp
on
tan
eo
us m
oto
r acti
vit
y s
co
re
Values are expressed as Mean ±SEM (n=6);
*(P<0.05), **(P<0.01) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.79 Effect of Alcoholic extract of roots of Prosopis chilensis on
Alertness(Hole Board test).
0
20
40
60
80
Control 100mg/kg AEPC 200mg/kg AEPC 300mg/kg AEPC
*
**
GROUPS
Nu
mb
er
of
head
dip
pin
gs
Values are expressed as Mean ±SEM (n=6);
*(P<0.05), **(P<0.01) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.80 Effect of Alcoholic extract of seeds of Prosopis chilensis on
motor co-ordination (Rota Rod test).
0
50
100
150
200
250
Control 100mg/kg AEPC 200mg/kg AEPC 300mg/kg AEPC
**
**
GROUPS
Rete
nti
on
tim
e in
seco
nd
s
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.81 Effect of Alcoholic extract of seeds of Prosopis chilensis on
immobility time in Tail suspension test.
0
50
100
150
200
Control 100mg/kg AEPC 200mg/kgAEPC 300mg/kgAEPC
**** **
GROUPS
Du
rati
on
of
imm
ob
ilit
y t
ime in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.82 Effect of Alcoholic extract of seeds of Prosopis chilensis on
immobility time in Forced swimming test
0
20
40
60
80
Control 100mg/kg AEPC 200mg/kg AEPC 300mg/kg AEPC
*
****
GROUPS
Du
rati
on
of
imm
ob
ilit
y t
ime in
sec
Values are expressed as Mean ±SEM (n=6);
*(P<0.05), **(P<0.01) Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.83 Effect of Alcoholic extract of seeds of Prosopis chilensis on
swimming time in Forced swimming test
0
50
100
150
200
250
Control 100mg/kg AEPC 200mg/kgAEPC 300mg/kgAEPC
****
**
GROUPS
Du
rati
on
of
sw
imm
ing
tim
e in
sec
Values are expressed as Mean ±SEM (n=6);
**(P<0.01) Vs Control group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.66 Effect of Alcoholic extract of Barleria prionities on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
***
**+++
++++++
+++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.67 Effect of Petroleum ether extract of Barleria prionities on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
******
***
*
++
+++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.68 Effect of Ethyl acetate extract of Barleria prionities on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
***
***
**+++
++++++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.69 Effect of Water extract of Barleria prionities
on lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
***
***
**
+++
++++++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.70 Effect of Alcoholic extract of Barleria prionities on reduced
glutathione in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
******
*+ ++
+++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), *** (P<0.001) Vs Control group;
+ (P<0.05), ++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.71 Effect of Petroleum ether extract of Barleria prionities
on reduced glutathione in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
********
++++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.72 Effect of Ethylacetate extract of Barleria prionities
on reduced glutathione in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** ******
*++ +++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.73 Effect of Water extract of Barleria prionities on
reduced glutathione in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
******
**+ +++ +++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig 28. Effect of Alcoholic extract of Canavalia gladiata on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
***
+++
++++++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.29 Effect of Petroleum ether extract of Canavalia gladiata on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
***
***
+++
+++++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), ** (P<0.01), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.30 Effect of Ethyl acetate extract of Canavalia gladiata on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
***
*
++++++
+
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.31 Effect of Water extract of Canavalia gladiata
on lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
***
*++
++++++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.32 Effect of Alcohol of Canavalia gladiata on reduced
glutathione level in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
*****+ +++ +++ +++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
**(P<0.01), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001)Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Values are expressed as Mean ± SEM (n=6);
**(P<0.01), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Fig.33 Effect of Petroleum ether extract of Canavalia gladiata on
reduced glutathione level in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
*** *** *****++ +++
GROUPS
m
ol/
mg
pro
tein
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.34 Effect of Ehyl acetate extract of Canavalia gladiata on
reduced glutathione level in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
*** *****
+++ ++++++
+
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
** (p<0.01), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.35 Effect of Water extract of Canavalia gladiata on
reduced glutathione level in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
******
**+ +++ +++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
**(P<0.01), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.103 Effect of Alcoholic extract of Prosopis chilensis on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kgPCE
***
***
**
++
+++
+++
+++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.104 Effect of Petroleum ether extract of Prosopis chilensis
on lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
***
******++
+++
+++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.105 Effect of Ethyl acetate extract of Prosopis chilensis
on lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
***
******
+++
+++
++
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.106 Effect of Water extract of Prosopis chilensis on
lipid peroxidation in MPTP treated mice.
0
20
40
60
80
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kgPCE+MPTP 300 mg/kgPCG
***
******
*+++
+++
+
GROUPS
nm
ol/m
g p
rote
in/h
r
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), *** (p<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.107 Effect of Alcoholic extract of Prosopis chilensis on
reduced glutathion level in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kgPCE
*** ***
**+ +++ +++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (p<0.001) Vs Control;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.108 Effect of Petroleum ether extract of Prosopis chilensis
on reduced glutathion level in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kgPCE
*** *** ******
+++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.109 Effect of Ethyl acetate extract of Prosopis chilensis on Reduced
glutathion level in MPTP treated mice
0
200
400
600
800
1000
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kgPCE+MPTP300 mg/kg PCE
*** ***** *
++++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), ** (P<0.01), *** (P<0.001) Vs Control;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.110 Effect of Water extract of Prosopis chilensis on
reduced glutathion level in MPTP treated mice.
0
200
400
600
800
1000
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kgPCE
*** ******
**
++++
GROUPS
m
ol/
mg
pro
tein
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.50 Effect of Alcoholic extract of Barleria prionities on
brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
******
******
***
++++++
++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.51 Effect of Petroleum ether extract of Barleria prionities on
brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** ******
*** ***++++++
++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.52 Effect of Ethyl acetate extract of Barleria prionities
on brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** ***
***
*** ***++++++
+++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.53 Effect of Water extract of Barleria prionities on
brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** ******
*** ***++++++
+++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.54 Effect of Alcoholic extract of Barleria prionities on
brain epinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** ******
++++++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001)Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.55 Effect of Petroleum ether extract of Barleria prionities on
brain epinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** *** ***
+++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.56 Effect of Ethyl acetate extract of Barleria prionities
on brain epinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** ***
***
++++++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6)
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.57 Effect of Water extract of Barleria prionities on
brain epinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** ***
***
+++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.58 Effect of Alcoholic extract of Barleria prionities on
brain norepinephrine level in MPTP treated mice
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** ***
***
++++++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6)
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.59 Effect of Petroleum ether extract of Barleria prionities on
brain norepinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** *** ***
**
+++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6)
**(P<0.01), *** (P<0.001) Vs Control group.
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.60 Effect of Ethyl acetate extract of Barleria prionities on
brain norepinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** ***
***
++++++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.61 Effect of Water extract of Barleria prionities on brain
norepinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** ***
***
++++++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.62 Effect of Alcoholic extract of Barleria prionities on
brain serotonin level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
****** ** **
+++
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
**(P<0.01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.63 Effect of Petroleum ether extract of Barleria prionities on
brain serotonin level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** *** *** ***
**+++
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
**(P<0.01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.64 Effect of Ethyl acetate extract of Barleria prionities on
brain serotonin level in MPTP treated mice
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
****** *** ***
*+++
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.65 Effect of Water extract of Barleria prionities on
brain serotonin level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg BPE+MPTP
200 mg/kg BPE+MPTP 300 mg/kg BPE+MPTP 300 mg/kg BPE
*** ****** ***
++++++
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+ (P<0.05), ++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig .12 Effect of Alcoholic extract of Canavalia gladiata
on brain dopamine in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
******
***
+++ ++++++
+
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.13 Effect of Petroleum ether extract of Canavalia gladiata on
brain dopamine level in MPTP treated mice
0
1
2
3
4
5
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
*** ******
******
++
++++++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
++ (P<0.01) , +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.14. Effect of Ethyl acetate extract of Canavalia gladiata
on brain dopamine level in MPTP treated mice
0
1
2
3
4
5
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
******
***
*** ***
+++
+++ +++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.15 Effect of Water extract of Canavalia gladiata on
brain dopamine level in MPTP pretreated mice
0
1
2
3
4
5
ControlMPTP 100mg/kg CGE+MPTP
200mg/kg CGE+MPTP 300mg/kg CGE+MPTP 300mg/kg CGE
******
***
*** ***
+++
+++ +++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group.
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.16 Effect of Alcoholic extract Canavalia gladiata on
brain epinephrine level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100mg/kg CGE+MPTP
200mg/kg CGE+MPTP 300mg/kg CGE+MPTP 300mg/kg CGE
***
** *+++ +++++++++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
* (P<0.005) , ** (P<0.01), ***(P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.17 Effect of Petroleum ether extract of Canavalia gladiata on
brain epinephrine level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
***** **
+++ +++ +++++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.18 Effect of Ethyl acetate extract of Canavalia gladiata on
brain epinephrine level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
*** *++++++++++++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig .19 Effect of water extract of Canavalia gladiata on brain epinephrine in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
** *
++++++++++++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), ** (P<0,01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.20 Effect of Alcoholic extract of Canavalia gladiata on
brain Norepinephrine level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
***
******
++++++++++++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.21 Effect of Petroleum ether extract of Canavalia gladiata on
brain Norepinephrine level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
*** ******
***
**+++
+++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group.
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.22 Effect of Ethyl acetate extract of Canavalia gladiata on
brain Norepinephrine level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
*** ***
***
+++ ++++++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group.
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig .23 Effect of Water extract of Canavalia gladiata on
brain norepinephrine in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
******
***
+++ ++++++
+
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group.
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.24 Effect of Alcoholic extract of Canavalia gladiata on
brain Serotonin level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
******
******
+++++++++
+++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.25 Effect of Petroleum ether extract of Canavalia gladiata on
brain Serotonin level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
*** *** ******
**+++
+++
GROUPS
sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
**(P<0.01), ***(P<0.001) Vs Control group.
+++(P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.26 Effect of Ethyl acetate extract of Canavalia gladiata on
brain Serotonin level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
****** ***
*** **++++++
+++
GROUPS
sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
+ (P<0.05), ++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 27 Effect of water extract of Canavalia gladiata on
brain Serotonin level in MPTP pretreated mice.
0
1
2
3
4
Control MPTP 100 mg/kg CGE+MPTP
200 mg/kg CGE+MPTP 300 mg/kg CGE+MPTP 300 mg/kg CGE
******
*** *++++++
++++
***
GROUPS
sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.87 Effect of Alcoholic extract of Prosopis chilensis on
brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP300 mg/kg PCE
*** *** ******
***+++
+++++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
++ (P<0.01), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.88 Effect of Petroleum ether extract of Prosopis chilensis on
brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** *** ******+++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.89 Effect of Ethyl acetate extract of Prosopis chilensis on
brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100mg/kg PCE+MPTP
200mg/kgPCE+MPTP 300mg/kg PCE+MPTP 300mg/kg PCE
*** *** ******
***+++
+++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.90 Effect of Water extract of Prosopis chilensis on
brain dopamine level in MPTP treated mice.
0
1
2
3
4
5
Control MPTP 100mg/kg PCE+MPTP
200mg kg PCE+MPTP 300mg/kg PCE+MPTP 300mg/kg PCE
*** *** ******
***+++
+++
GROUPS
Do
pam
ine(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.91 Effect of Alcoholic extract of Prosopis chilensis on
brain epinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100mg/kg PCE+MPTP
200mg/kg PCE+MPTP 300mg/kg PCE+MPTP 300mg/kg PCE
*** ******
**
+++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
** (P<0.01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.92 Effect of Petroleum ether extract of Prosopis chilensis
on brain epinephrine level in MPTP treated mice
0
1
2
3
4
Control MPTP 100mg/kg PCE+MPTP
200mg/kg PCE+MPTP 300mg/kg PCE+MPTP 300mg/kg PCE
*** *** ******
*+++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e
Values are expressed as Mean ± SEM (n=6);
*(P<0.05), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.93 Effect of Ethyl acetate extract of Prosopis chilensis on
brain epinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** ******
+++ +
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.94 Effect of Water extract of Prosopis chilensis on
brain epinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
****** *** ***
+++
GROUPS
Ep
inep
hri
ne(u
g/g
tis
su
e
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.95 Effect of Alcoholic extract of Prosopis chilensis on
brain norepinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** *** ***
++++++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.96 Effect of Petroleum ether extract of Prosopis chilensis on
brain norepinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** *** ***
+++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.97 Effect of Ethyl acetate extract of Prosopis chilensis on brain
norepinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** ******
**+++
++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
**(P<0.01), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.98 Effect of Water extract of Prosopis chilensis on
brain norepinephrine level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** ******
++++++
GROUPS
No
rep
inep
hri
ne(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.99 Effect of Alcoholic extract of Prosopis chilensis on brain
serotonin level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
****** ***
****
++++++
+
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), *** (P<0.001) Vs Control group;
+ (P<0.05), +++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.100 Effect of Petroleum ether extract of Prosopis chilensis
on brain serotonin level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** *** ***
***+++
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.101 Effect of Ethyl acetate extract of Prosopis chilensis on
brain serotonin level in MPTP treated mice.
0
1
2
3
4
Control MPTP100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** *** *** ***
+++
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
*** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.102 Effect of Water extract of Prosopis chilensis on
brain Serotonin level in MPTP treated mice.
0
1
2
3
4
Control MPTP 100 mg/kg PCE+MPTP
200 mg/kg PCE+MPTP 300 mg/kg PCE+MPTP 300 mg/kg PCE
*** ****** ***
*+++
+++++
GROUPS
Sero
ton
in(u
g/g
tis
su
e)
Values are expressed as Mean ± SEM (n=6);
* (P<0.05), *** (P<0.001) Vs Control group;
+++ (P<0.001) Vs MPTP group.
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.74 Effect of alcoholic extract of Barleria prionities on
DPPH
0
10
20
30
40
50
60
70
80
90
100
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
DPPH
IC50 360μg/ml ---- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.75 Effect of alcoholic extract of Barleria prionities on
Lipid peroxidation
0
10
20
30
40
50
60
70
80
90
100
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
LPO
Fig.76 Effect of alcoholic extract of Barleria prionities on
Nitric Oxide
0
10
20
30
40
50
60
70
80
90
100
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
NO
IC 50 380μg/ml
IC50 390μg/ml
----- Linear
----- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.77 Effect of alcoholic extract of Barleria prionities on
Superoxide Dismutase
0
10
20
30
40
50
60
70
80
90
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
SOD
IC50 400μg/ml ----- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.36 Effect of alcoholic extract of Canavalia gladiata
on DPPH
0
10
20
30
40
50
60
70
80
90
100
0 200 400 600 800 1000
Concentration (ug/ml)
% In
hib
itio
n
DPPH
Fig.37 Effect of alcoholic extract of Canavalia gladiata on
Lipid peroxidation
0
10
20
30
40
50
60
70
80
90
100
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
LP
O
--- Linear
IC50 300 μg/ml
IC 50 340μg/ml ---- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig. 38 Effect of alcoholic extract of Canavalia gladiata
on Nitric oxide
0
20
40
60
80
100
0 200 400 600 800 1000
Concentration (ug/ml)
% In
hib
itio
n
NO
IC50 320μg/ml ---- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.39 Effect of alcoholi extract of Canavalia gladiata on
Superoxide Dismutase
0
10
20
30
40
50
60
70
80
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
SOD
IC 50 510μg/ml
5105105555510510
510510μg/ml
---- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.135 Effect of alcoholic extract of Capparis zeylanica
on DPPH
0
10
20
30
40
50
60
70
80
90
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
DPPH
---- Linear IC50 410µg/ml
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.136 Effect of alcoholic extract of Capparis zeylanica
on Lipid peroxidation
0
10
20
30
40
50
60
70
80
90
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
LPO
--- Linear IC50 340µg/ml
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.137 Effect of alcoholic extract of Capparis zeylanica
on Nitric Oxide Scavenging
0
10
20
30
40
50
60
70
80
90
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
NO
Fig.138 Effect of alcoholic extract of Capparis zeylanica
on Superoxide Dismutase
0
10
20
30
40
50
60
70
80
90
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
SOD
---- Linear IC50 430µg/ml
---- Linear IC50 400µg/ml
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
‘
Fig.123 Effect of alcoholic extract of Dichrostachys
cinerea on DPPH
0
10
20
30
40
50
60
70
80
90
100
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
DPPH
IC50 340μg/ml ---- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.124 Effect of alcoholic extract of Dichrostachys
cinerea on Lipid peroxidation
0
10
20
30
40
50
60
70
80
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
LPO
Fig. 125 Effect of alcoholic extract of Dichrostacys
cinerea on Nitric Oxide Scavenging
0
10
20
30
40
50
60
70
80
90
0 200 400 600 800 1000
Concentration (ug/ml)
% I
nh
ibit
ion
NO
IC50 410μg/ml
IC50 420μg/ml ---- Linear
Barleria prionities - Results
Institute of Pharmaceutical Technology, SPMVV, Tirupati.
Fig.126 Effect of alcoholic extract of Dichrostachys
cinerea on Superoxide Dismutase
0
10
20
30
40
50
60
70
80
90
100
0 200 400 600 800 1000
Concentration(ug/ml)
% I
nh
ibit
ion
SOD
IC50 380μg/ml ---- Linear
