Topics for Micro160 Exam 1 WED 10/7 Bartlett 9:05 AM

Note: This list of topics, is meant as a guide to keep in mind while reviewing the lecture slides.

Material covered in the Kleinsmith text includes chapters 1-3 and the first part of chapter 4

Life expectancy and its effects on Cancer rates

Nature of disease

Germ theory of Disease VS Spontaneous Generation

Pasteurs experiment

Kochs postulates

Griffths experiment

DNA as an information storage molecule

Parts of a cell

Molecular Dogma: DNA - RNA protein

Replication, Transcription, Translation

Cancer cell profile

telomerase

Triplet code: 1 tRNA- 3 nucleotides = 1 Amino acid

Types of genes commonly mutated in cancer

Growth factor signaling

Experiments leading to isolation of VEGF and Avastin

Personalized medicine, biomarkers

Immune recognition: Self VS tumor antigen

Evidence for Immune system attacking tumors

T cells, B cells, Antigen presenting cells

Epidemiology methods

Risk

Mitotic index

Ames test for promutagens

Incidence, Prevalence, Mortality

Cohort studies, control groups